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QBA - Prisma - Unidad de Bibliometría

QUÍMICA DE BIOMOLÉCULAS Y ANÁLOGOS - FQM-345 (QBA)

Tipo de colectivo: Grupo de investigación
Estado: Grupo definitivo
Ámbito: Andalucía
Instituciones: Universidad de Sevilla
Fecha de creación: 08/07/2004

Investiga en

Palabras clave
Líneas de investigación
Resumen
Nombre Rol
Carmona Asenjo, Ana Teresa Investigadora principal
Carranza Cesar, Marina Miembro
Martinez Bailen, Macarena Miembro
Moreno Vargas, Antonio José Miembro
Robina Ramírez, Inmaculada Miembro
Tipo Año Título Fuente
Artículo2023 Experimental and Theoretical Analysis of the Thiol-Promoted Fragmentation of 2-Halo-3-tosyl-oxanorbornadienes. ORGANIC LETTERS
Artículo2023 Molecular response of cocoa (Theobroma cacao) to water deficit conditions JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS
Revisión2023 Multivalent glycosystems for human lectins CHEMICAL SOCIETY REVIEWS
Artículo2023 Stereoselective Synthesis of Heavily Hydroxylated Azepane Iminosugars via Osmium-Catalyzed Tethered Aminohydroxylation ORGANIC LETTERS
Artículo2023 Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2023 Transferring Substituents from Alkynes to Furans and Pyrroles through Heteronorbornadienes as Intermediates: Synthesis of β-Substituted Pyrroles/Furans JOURNAL OF ORGANIC CHEMISTRY
Artículo2022 Antimicrobial activity of phenolics isolated from the pruning wood residue of European plum (Prunus domestica L.) INDUSTRIAL CROPS AND PRODUCTS
Artículo2022 Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease BIOORGANIC CHEMISTRY
Artículo2022 Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars BIOORGANIC CHEMISTRY
Revisión2022 GCase Enhancers: A Potential Therapeutic Option for Gaucher Disease and Other Neurological Disorders PHARMACEUTICALS
Artículo2022 Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2022 Iminosugar-phosphines as organocatalysts in the [3 + 2] cycloaddition of allenoates and N-tosylimines CATALYSTS
Artículo2022 Inter-Ligand STD NMR: an efficient 1D NMR approach to probe relative orientation of ligands in a multi-subsite protein binding pocket PHARMACEUTICALS
Artículo2022 Structure-based identification and biological characterization of new NAPRT inhibitors PHARMACEUTICALS
Artículo2022 Studies on the regioselective rearrangement of azanorbornanic aminyl radicals into 2,8-diazabicyclo[3.2.1]oct-2-ene systems. JOURNAL OF ORGANIC CHEMISTRY
Artículo2022 Synthesis of a New beta-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis MOLECULES
Artículo2021 Piperidine Azasugars Bearing Lipophilic Chains: Stereoselective Synthesis and Biological Activity as Inhibitors of Glucocerebrosidase (GCase) JOURNAL OF ORGANIC CHEMISTRY
Otros2021 Técnicas básicas en un laboratorio de química orgánica: calentamiento a reflujo. Síntesis de acetanilida Portal de Vídeo Didáctico de la Universidad de Sevilla
Otros2021 Técnicas básicas en un laboratorio de química orgánica: cromatografía en capa fina. Portal de Vídeo Didáctico de la Universidad de Sevilla
Otros2021 Técnicas básicas en un laboratorio de química orgánica: cromatografía en columna de gel de sílice. Portal de Vídeo Didáctico de la Universidad de Sevilla
Otros2021 Técnicas básicas en un laboratorio de química orgánica: destilación simple. Portal de Vídeo Didáctico de la Universidad de Sevilla
Otros2021 Técnicas básicas en un laboratorio de química orgánica: recristalización Portal de Vídeo Didáctico de la Universidad de Sevilla
Otros2021 Técnicas básicas en un laboratorio de química orgánica: separación por extracción Portal de Vídeo Didáctico de la Universidad de Sevilla
Artículo2020 Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules MOLECULAR DIVERSITY
Artículo2020 Exploring Multi-Subsite Binding Pockets in Proteins: DEEP-STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B CHEMISTRY-A EUROPEAN JOURNAL
Artículo2020 Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning BIOORGANIC CHEMISTRY
Artículo2020 Influence of the surfactant degree of oligomerization on the formation of cyclodextrin: surfactant inclusion complexes Arabian Journal of Chemistry
Artículo2020 Regioselectivity of the 1,3-Dipolar Cycloaddition of Organic Azides to 7-Heteronorbornadienes. Synthesis of beta-Substituted Furans/Pyrroles JOURNAL OF ORGANIC CHEMISTRY
Artículo2020 Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Artículo2020 Synthesis of "all-cis" trihydroxypiperidines from a carbohydrate-derived ketone: Hints for the design of new β-gal and gcase inhibitors MOLECULES
Artículo2020 Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry disease EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2019 Azabicyclic vinyl sulfones for residue-specific dual protein labelling Electronic supplementary information (ESI) available: Detailed methods and additional characterisation. See DOI: 10.1039/c9sc00125e CHEMICAL SCIENCE
Artículo2019 Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes BIOORGANIC CHEMISTRY
Artículo2019 Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of beta-glucocerebrosidase inhibition BIOORGANIC CHEMISTRY
Artículo2019 Preparation of water-soluble glycopolymers derived from five-membered iminosugars EUROPEAN POLYMER JOURNAL
Artículo2019 Structural basis of the inhibition of GH1 β-glucosidases by multivalent pyrrolidine iminosugars BIOORGANIC CHEMISTRY
Artículo2018 Amino-P Ligands from Iminosugars: New Readily Available and Modular Ligands for Enantioselective Pd-Catalyzed Allylic Substitutions ORGANOMETALLICS
Artículo2018 Discovery of a Potent alpha-Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine-(Thio)urea Hybrid Molecules Generated via Click Chemistry JOURNAL OF ORGANIC CHEMISTRY
Artículo2018 Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2018 Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2018 Pyrrolidine-Based P,O Ligands from Carbohydrates: Easily Accessible and Modular Ligands for the Ir-Catalyzed Asymmetric Hydrogenation of Minimally Functionalized Olefins CHEMCATCHEM
Artículo2017 Epididymal alpha-L-fucosidase and its possible role in remodelling the surface of bull spermatozoa THERIOGENOLOGY
Artículo2017 Host-guest interactions between cyclodextrins and surfactants with functional groups at the end of the hydrophobic tail JOURNAL OF COLLOID AND INTERFACE SCIENCE
Artículo2017 Mechanistic Insight into the Binding of Multivalent Pyrrolidines to alpha-Mannosidases CHEMISTRY-A EUROPEAN JOURNAL
Artículo2017 Tuning of beta-glucosidase and alpha-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2016 Cycloadditions of Sugar-Derived Nitrones Targeting Polyhydroxylated Indolizidines EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Revisión2016 Diels-Alder Approaches for the Synthesis of Bridged Bicyclic Systems: Synthetic Applications of (7-hetero)norbornadienes CURRENT ORGANIC CHEMISTRY
Artículo2016 Expanding the library of divalent fucosidase inhibitors with polyamino and triazole-benzyl bridged bispyrrolidines ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2016 Exploring the divalent effect in fucosidase inhibition with stereoisomeric pyrrolidine dimers ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2015 Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Artículo2015 Gold nanoparticles are suitable cores for building tunable iminosugar multivalency RSC ADVANCES
Editorial2015 Meet Our Editorial Board Member Current Organic Synthesis
Artículo2015 Reversibility of the interactions between a novel surfactant derived from lysine and biomolecules COLLOIDS AND SURFACES B-BIOINTERFACES
Artículo2015 Synthesis of 1,2,3-triazole-linked glycohybrids in the gluco-, gulo-, and allopyranose series CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Artículo2014 6-Azido hyacinthacine A(2) gives a straightforward access to the first multivalent pyrrolizidine architectures ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2014 Polyhydroxyamino-Piperidine-Type Iminosugars and Pipecolic Acid Analogues from a D-Mannose-Derived Aldehyde EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2014 Rapid discovery of potent alpha-fucosidase inhibitors by in situ screening of a library of (pyrrolidin-2-yl)triazoles ORGANIC & BIOMOLECULAR CHEMISTRY
Ponencia2014 Rapid discovery of potent α-L-fucosidase inhibitors by "in situ" screening of (pyrrolidin-2-yl)triazoles XI Carbohydrate Symposium
Ponencia2014 Synthesis and biological evaluation of furyl galactosides and non-carbohydrate multivalent ligands with affinity towards enterotoxins XI Carbohydrate Symposium
Artículo2014 Synthesis and cancer growth inhibitory activities of 2-fatty-alkylated pyrrolidine-3,4-diol derivatives ARKIVOC
Artículo2014 Synthesis of 7-Oxabicyclo[2.2.1]heptane and Derivatives SYNTHESIS OF SATURATED OXYGENATED HETEROCYCLES I: 5- AND 6- MEMBERED RINGS
Artículo2014 Synthesis of pyrrolidine 3,4-diol derivatives with anticancer activity on pancreatic tumor cells HETEROCYCLES
Artículo2013 Exploring a Multivalent Approach to alpha-L-Fucosidase Inhibition EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Capítulo2013 Glycosylation Methods in Oligosaccharide Synthesis Advances in Organic Synthesis (Volumen 6)
Artículo2013 Strain-promoted retro-Dieckmann-type condensation on [2.2.2]- and [2.2.1]bicyclic systems: a fragmentation reaction for the preparation of functionalized heterocycles and carbocycles ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2013 Synthesis and Glycosidase Inhibition Studies of 5-Methyl-Substituted Tetrahydroxyindolizidines and -pyrrolizidines Related to Natural Hyacinthacines B EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2013 Synthesis, Biological Evaluation, WAC and NMR Studies of S-Galactosides and Non-Carbohydrate Ligands of Cholera Toxin Based on Polyhydroxyalkylfuroate Moieties CHEMISTRY-A EUROPEAN JOURNAL
Artículo2013 Three dimensional structure of a bacterial alpha-L-fucosidase with a 5-membered iminocyclitol inhibitor BIOORGANIC & MEDICINAL CHEMISTRY
Artículo2012 Synthesis and physicochemical characterization of alkanedyil-alpha-omega-bis (dimethyldodecylammonium) bromide, 12-s-12,2Br(-), surfactants with s=7, 9, 11 in aqueous medium JOURNAL OF COLLOID AND INTERFACE SCIENCE
Artículo2012 Synthesis of novel 3-deoxy-3-C-triazolylmethyl-allose derivatives and evaluation of their biological activity CENTRAL EUROPEAN JOURNAL OF CHEMISTRY
Artículo2011 Amine-linked diglycosides: Synthesis facilitated by the enhanced reactivity of allylic electrophiles, and glycosidase inhibition assays BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Artículo2011 Diversity-oriented syntheses of 7-substituted lentiginosines TETRAHEDRON
Artículo2011 Exploiting the Ring Strain in Bicyclo[2.2.1]heptane Systems for the Stereoselective Preparation of Highly Functionalized Cyclopentene, Dihydrofuran, Pyrroline, and Pyrrolidine Scaffolds ORGANIC LETTERS
Artículo2011 Monosaccharides and Analogues from Simple Achiral Unsaturated Compounds CHIMIA
Artículo2011 Physicochemical characterization of bromide mono- and dimeric surfactants with phenyl and cyclohexyl rings in the head group JOURNAL OF COLLOID AND INTERFACE SCIENCE
Artículo2011 Syntheses and Biological Activities of 1,4-Iminoalditol Derivatives as alpha-L-Fucosidase Inhibitors CHIMIA
Artículo2011 Syntheses and Biological Activities of Iminosugars as alpha-L-Fucosidase Inhibitors Current Organic Synthesis
Artículo2011 Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers SYNTHESIS-STUTTGART
Artículo2011 Total Asymmetric Synthesis of Monosaccharides and Analogues CHIMIA
Artículo2011 Total Synthesis of (+)-Hyacinthacine A1, (+)-7a-epi-Hyacinthacine A1, (6R)-6-Hydroxyhyacinthacine A1 and (6S)-6-Hydroxy-7a-epi-hyacinthacine A1 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2010 New Methodology for the Stereoselective Synthesis of alpha-Furfurylamines from Sugars: Application to the Synthesis of Furyl Amino Acids and 3-Furylisoserines EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2010 Study of the Micellization and Micellar Growth in Pure Alkanediyl-alpha-omega-Bis(dodecyldimethylammonium) Bromide and MEGA10 Surfactant Solutions and Their Mixtures. Influence of the Spacer on the Enthalpy Change Accompanying Sphere-to-Rod Transitions JOURNAL OF PHYSICAL CHEMISTRY B
Artículo2010 Synthesis and inhibitory activities of novel C-3 substituted azafagomines: A new type of selective inhibitors of alpha-L-fucosidases BIOORGANIC & MEDICINAL CHEMISTRY
Artículo2010 Synthesis of a C-3-Symmetric Furyl-Cyclopeptide Platform with Anion Recognition Properties EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2010 Synthesis of Novel 3-Amino(Hydroxy)methyl-L-fuco-Azafagomines as Leads for Selective Inhibitors of alpha-L-Fucosidases SYNLETT
Artículo2010 The regioselectivity of the addition of benzeneselenyl chloride to 7-azanorborn-5-ene-2-yl derivatives is controlled by the 2-substituent: new entry into 3-and 4-hydroxy-5-substituted prolines TETRAHEDRON
Artículo2009 Allenyl Sulfones and Allenyl Sulfides in the Synthesis of 3-Pyrrolines. A Novel Nucleophilic [3+2] Cycloaddition on Allenyl Sulfones Giving Rearranged Cycloadducts ORGANIC LETTERS
Artículo2009 Stereoselective synthesis of 1,2-cis-glycosylic linkages CARBOHYDRATE CHEMISTRY: CHEMICAL AND BIOLOGICAL APPROACHES, VOL 35
Artículo2009 Synthesis of novel pyrrolidine 3,4-diol derivatives as inhibitors of alpha-L-fucosidases ORGANIC & BIOMOLECULAR CHEMISTRY
Revisión2008 Glycosylation methods in oligosaccharide synthesis. Part 1 Current Organic Synthesis
Revisión2008 Glycosylation methods in oligosaccharide synthesis. Part 2 Current Organic Synthesis
Artículo2008 Mixtures of monomeric and dimeric surfactants: Hydrophobic chain length and spacer group length effects on non ideality JOURNAL OF PHYSICAL CHEMISTRY B
Artículo2008 Synthesis and biological evaluation of S-neofucopeptides as E- and P-selectin inhibitors EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Ponencia2007 CARB 67-Approaches to novel sialyl Lewis X mimetics: S-Linked fucoside derivatives ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
Ponencia2007 Conformational analysis of HIV gp41 inhibitors ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
Artículo2007 Micellar kinetic effects in gemini micellar solutions: Influence of sphere-to-rod transitions on kinetics JOURNAL OF COLLOID AND INTERFACE SCIENCE
Artículo2007 Stereoselective synthesis of novel five-membered homoazasugars. A convenient route to all-cis tetrasubstituted pyrrolidines TETRAHEDRON LETTERS
Artículo2007 Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins BIOORGANIC & MEDICINAL CHEMISTRY
Artículo2007 Synthesis and conformational analysis of novel trimeric maleimide cross-linking reagents JOURNAL OF ORGANIC CHEMISTRY
Capítulo2007 Synthesis of Monosaccharides and Analogs Comprehensive Glycoscience: From Chemistry to Systems Biology
Artículo2007 Synthesis of monosaccharides and analogues - Part one: applications of chemo-enzymatic methods and organocatalysis CHIMICA OGGI-CHEMISTRY TODAY
Artículo2007 Synthesis of monosaccharides and analogues - Part three: Monosaccharides from simple achiral unsaturated compounds CHIMICA OGGI-CHEMISTRY TODAY
Artículo2007 Synthesis of monosaccharides and analogues Part two: Chain elongation of aldehydes CHIMICA OGGI-CHEMISTRY TODAY
Artículo2006 Asymmetric synthesis of the polyol subunit of the polyene macrolide antibiotic RK-397 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2006 Cyanodeoxy-glycosyl derivatives as substrates for enzymatic reactions EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Corrección2006 Cyanodeoxy-glycosyl derivatives as substrates for enzymatic reactions (April, pg 1876, 2006) EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2006 Effects of ethylene glycol addition on the aggregation and micellar growth of gemini surfactants LANGMUIR
Artículo2006 Stereoselective synthesis of chiral furan amino acid analogues of D- and L-serine from D-sugars SYNLETT
Artículo2005 Glycosyl azide - a novel substrate for enzymatic transglycosylations TETRAHEDRON LETTERS
Artículo2005 Noniterative approach to the total asymmetric synthesis of 15-carbon polyketides and analogs with high stereodiversity PURE AND APPLIED CHEMISTRY
Capítulo2005 Programa de equipos docentes para la formación de profesores noveles La formación del profesorado universitario: programa de equipos docentes de la Universidad de Sevilla, curso 2003-2004
Artículo2005 Stereoselective synthesis of (2S,3S,4R,5S)-5-methylpyrrolidine-3,4-diol derivatives that are highly selective alpha-L-fucosidase inhibitors CHEMICAL COMMUNICATIONS
Revisión2005 Synthesis of aza-C-disaccharides (dideoxyimino-alditols C-linked to monosaccharides) and analogues SYNTHESIS-STUTTGART
Artículo2004 Fluorination of 2-hydroxy-hexopyranosides by DAST: towards formyl C-glycofuranosides from equatorial-2-OH methyl hexopyranosides TETRAHEDRON-ASYMMETRY
Revisión2004 Glycosidase inhibitors as potential HIV entry inhibitors? CURRENT DRUG METABOLISM
Artículo2004 Stereoselective synthesis of novel tetrahydroxypyrrolizidines TETRAHEDRON-ASYMMETRY
Artículo2004 Synthesis of D- and L-2,3-trans-3,4-cis-4,5-trans-3,4-dihydroxy-5-hydroxymethylproline and tripeptides containing them JOURNAL OF ORGANIC CHEMISTRY
Artículo2003 Efficient resolution of N-Boc-7-azabicyclo[2.2.1]hept-5-en-2-one: formal syntheses of natural epibatidine and its enantiomer TETRAHEDRON-ASYMMETRY
Artículo2003 Hetaryleneaminopolyols and hetarylenecarbopeptoids: a new type of glyco- and peptidomimetics. Syntheses and studies on solution conformation and dynamics JOURNAL OF ORGANIC CHEMISTRY
Artículo2003 Regioselective rearrangement of 7-azabicyclo[2.2.1]hept-2-aminyl radicals: first synthesis of 2,8-diazabicyclo[3.2.1]oct-2-enes and their conversion into 5-(2-aminoethyl)-2,3,4-trihydroxypyrrolidines, new inhibitors of alpha-mannosidases TETRAHEDRON LETTERS
Artículo2003 Specific activation of ERK pathways by chitin oligosaccharides in embryonic zebrafish cell lines GLYCOBIOLOGY
Artículo2003 Stereoselective syntheses of 1,4-dideoxy-1,4-imino-octitols and novel tetrahydroxyindolizidines JOURNAL OF ORGANIC CHEMISTRY
Artículo2003 Synthesis and glycosidase inhibitory activities of 2-(aminoalkyl)pyrrolidine-3,4-diol derivatives BIOORGANIC & MEDICINAL CHEMISTRY
Artículo2003 Synthesis and glycosidase inhibitory activities of 5-(1 ',4 '-dideoxy-1 ',4 '-imino-D-erythrosyl)-2-methyl-3-furoic acid (=5-[3S, 4R)-3,4-dihydroxypyrrolidin-2-yl]-2-methylfuran-3-carboxylic acid) derivitives: New leads as selective alpha-L-fucosidase and beta-galactosidase inhibitors HELVETICA CHIMICA ACTA
Artículo2003 Synthesis and glycosidase inhibitory activity of 7-deoxycasuarine HELVETICA CHIMICA ACTA
Artículo2003 Synthesis of enantiomerically pure 1,2-diamine derivatives of 7-azabicyclo[2.2.1]heptane. New leads as glycosidase inhibitors and rigid scaffolds for the preparation of peptide analogues JOURNAL OF ORGANIC CHEMISTRY
Artículo2002 A convenient stereoselective route to novel tetrahydroxyindolizidines TETRAHEDRON LETTERS
Artículo2002 An efficient combinatorial method for the discovery of glycosidase inhibitors CHEMBIOCHEM
Artículo2002 Expeditious synthesis of cyclic isourea derivatives of beta-D-glucopyranosylamine TETRAHEDRON LETTERS
Artículo2002 Synthesis and biological evaluation of oligosaccharides related to the molecule signals in plant defence and the Rhizobium-legume symbiosis TETRAHEDRON
Artículo2002 Synthesis of (1→3)-C and homo(1→3)-C-linked imino-disaccharides starting from levoglucosenone and isolevoglucosenone HETEROCYCLES
Artículo2002 Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: New leads as selective beta-galactosidase inhibitors BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Artículo2002 Synthesis of tri-and tetramines containing two 2,3-dihydroxypyrrolidine moieties and their inhibitory activity toward alpha-mannosidases ARKIVOC
Revisión2002 The synthesis of disaccharides, oligosaccharides and analogues containing thiosugars CURRENT ORGANIC CHEMISTRY
Artículo2001 A practical one-pot synthesis of O-unprotected glycosyl thioureas TETRAHEDRON LETTERS
Artículo2001 Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Artículo2001 New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Artículo2001 Reactivity of polyhydroxyalkyl-heterocycles towards Lewis acids TETRAHEDRON-ASYMMETRY
Artículo2001 Solution and solid phase synthesis of hetarylene-carbopeptoids. A new type of peptidomimetics TETRAHEDRON LETTERS
Revisión2001 Synthesis and biological properties of monothiosaccharides CURRENT ORGANIC CHEMISTRY
Artículo2000 Glycosidase inhibition by phenylsulfinyl 2-deoxy-2-tetrachloro-phthalimido-beta-d-glucopyranoside and derivatives. Carbohydrate letters (Print)
Artículo2000 Rearrangement reactions in the fluorination of 3-deoxy-3-C-methyl-3-nitro-hexopyranosides (and hexo-1-thiopyranosides) of the D- and L-series by the DAST reagent TETRAHEDRON-ASYMMETRY
Artículo2000 Synthesis of (Z)-3-deoxy-3-(1,2,3,6-tetradeoxy-3,6-imino-L-arabino-hexitol-1-C-ylidene)-D-xylo-hexose derivatives. First examples of homo-(1 -> 3)-C-linked iminodisaccharides JOURNAL OF CARBOHYDRATE CHEMISTRY
Artículo1999 Branched-chain fluoro nitro D- and L-sugars from glucose TETRAHEDRON-ASYMMETRY
Artículo1999 Stereoselective synthesis of imidazolidine, imidazoline and imidazole C- and N-pseudonucleosides TETRAHEDRON-ASYMMETRY
Artículo1999 Sugar isothiocyanate-sugar thiocarbamate equilibrium. synthesis of thiourea derivatives of methyl 2-amino-2-deoxy-a-d-glucopyranoside Carbohydrate letters (Print)
Artículo1999 Synthesis of 2-acylamino-2-deoxy-D-glucofuranoses and their transformation into hex-2-enofuranoses CARBOHYDRATE RESEARCH
Artículo1999 Synthesis of five-membered homothiosugars derived from L-erythrose and D-mannose TETRAHEDRON-ASYMMETRY
Artículo1998 Introduction of C-sulfonate groups into disaccharide derivatives SYNTHETIC COMMUNICATIONS
Artículo1998 Oxidation of polyhydroxyalkyl-heterocycles by cerium - (IV). A convenient route to pyrrole-2,5-dicarbaldehydes. TETRAHEDRON LETTERS
Corrección1997 Erratum: Synthesis and conformational analysis of a lipotetrasaccharide related to the nodulation factor of Rhizobium bacteria (Tetrahedron: Asymmetry (1997) 8 (1207-1224) PII: S0957416697001080) TETRAHEDRON-ASYMMETRY
Artículo1997 Synthesis and conformational analysis of a lipotetrasaccharide related to the nodulation factor of Rhizobium bacteria TETRAHEDRON-ASYMMETRY
Corrección1997 Synthesis and conformational analysis of a lipotetrasaccharide related to the nodulation factor of Rhizobium bacteria (vol 8, pg 1207, 1997) TETRAHEDRON-ASYMMETRY
Artículo1996 Fatty acylamino-trisaccharides. Synthesis and some stereochemical properties. TETRAHEDRON
Artículo1996 Synthesis of glycosyl acceptors by regioselective benzylations of a 2-deoxy-2-phthalimido-D-glucoside. SYNTHETIC COMMUNICATIONS
Artículo1995 Regioselective glycosylation of n-protected l-rhamno(fuco) pyranosylamines - preparation and spectroscopic characterization of building-blocks for neoglycoconjugate syntheses JOURNAL OF CARBOHYDRATE CHEMISTRY
Nota1994 A d-ribofuranosylenamine as glycosyl acceptor CARBOHYDRATE RESEARCH
Artículo1993 Tri-o-benzoyl-beta-l-rhamnopyranosyl and beta-l-fucopyranosyl isothiocyanates - partially protected beta-l-rhamnopyranosylenamines CARBOHYDRATE RESEARCH
Artículo1992 Glucosylenamines as glycosyl acceptors - synthesis of gentiobiosylenamines CARBOHYDRATE RESEARCH
Nota1992 Omega-chlorination of derivatives of some 3-(pentitol-1-yl)-pyrazoles Journal of Chemical Research
Artículo1992 Partially protected d-glucopyranosyl isothiocyanates - synthesis and transformations into thiourea and heterocyclic-derivatives TETRAHEDRON
Artículo1991 Preparation and properties of 2-deoxyglycosyl isothiocyanates TETRAHEDRON
Artículo1990 Cyclodehydration of 3-(d-manno-pentitol-l-yl)pyrazoles - synthesis of 3-(d-arabinofuranosyl)pyrazoles CARBOHYDRATE RESEARCH
Nota1990 Diastereoselective conjugate addition of ammonia in the synthesis of chiral pyrrolidines JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Artículo1990 New synthesis of 1-alkyl(aryl)-2,3-dihydro-2-thioxo-1h-imidazole-4-carboxaldehydes JOURNAL OF ORGANIC CHEMISTRY
Libro1988 Problemas de mecanismos de reacción en química orgánica Problemas de mecanismos de reacción en química orgánica
Artículo1986 C-glycosides of imidazoles .10. 1-alkyl(aryl h)-3-alkyl-4-(beta-d-erythofuranosyl)-1,3-dihydro-2h-imidazol-2-thiones ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1985 Derivados del pirrol XXVII. Polihidroxialquilnitropirroles ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1985 Derivados del pirrol. XXVII. Polihidroxialquilnitropirroles Anales de la Real Sociedad Española de Química
Artículo1984 Derivados del pirrol. XXVI. 4- [ ∝ y β-D-eritro(D-treo) furanosil]-3-etoxicarbonil-1,2-dimetilpirroles ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1984 Pyrrol derivatives .26. 4-[alpha-d-erythere(d-threo)furanosyl]-3-ethoxy-carbonyl-1,2-dimethylpyrrole and beta-d-erythere(d-threo)furanosyl]-3-ethoxy-carbonyl-1,2-dimethylpyrroles ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1983 Derivados del pirrol. XXV. Reacción de metilaminohexosas con compuestos β-dicarbonílicos ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA

Proyectos de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
05/10/2021 30/06/2023 Sistemas (hetero) norbornadiénicos como conectores en conjugados fármaco-anticuerpo (ADCs) (P20_00532) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 90.000,00 €
01/09/2021 28/02/2025 Sistemas químicos para la vectorización y liberación selectiva de nuevos inhibidores enzimáticos citotóxicos (PID2020-116460RB-I00) Ministerio de Ciencia e Innovación (Nacional) 84.700,00 €
01/11/2018 30/04/2023 Integrating chemical and biological approaches to target NAD production and signaling in cancerIntegrating chemical and biological approaches to target NAD productión and signaling in cáncer - INTEGRATA (H2020-813284) Comisión Europea (Europeo) 232.349,32 €
30/12/2016 31/12/2020 Diseño y Síntesis de Moléculas de Interés Biológico Mediante el Desarrollo de Metodologías Sintéticas (CTQ2016-77270-R) Ministerio de Economía y Competitividad (Nacional) 68.970,00 €
30/01/2014 16/06/2019 Nuevos Tensioactivos Biodegradables. Estudio de sus Propiedades Fisicoquímicas y Biológicas y de sus Interacciones con Especies de Potencial Interés Aplicado (P12-FQM-1105) Consejería de Economía, Innovación y Ciencia (Autonómico) 176.361,25 €
01/01/2013 31/12/2015 Nuevas Aproximaciones Sintéticas para la Preparación de Moléculas Bioactivas (CTQ2012-31247) Ministerio de Economía y Competitividad (Nacional) 51.480,00 €
01/03/2011 28/02/2016 Integrating chemical approaches to treat pancreatic cancer: making new leads for a cure - (Nº 256986) PANACREAS (256986) Comisión Europea (Europeo) 155.896,00 €
01/01/2009 31/12/2012 Nuevas metodologías sintéticas para la preparación de moléculas bioactivas y de sus análogos (CTQ2008-01565) Ministerio de Educación y Ciencia (Nacional) 90.750,00 €
31/01/2008 31/12/2012 Preparación y Estudio de Nuevos Surfactantes Multicatenarios de Alto Valor Añadido a partir de Materias Primas Renovables (P07-FQM-03056) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 90.585,00 €
01/12/2007 30/11/2008 Diseño y síntesis de nuevos inhibidores enzimáticos, de análogos del sialil lewis X y de antibióticos aminoglicosídicos. Evaluación biológica (CTQ2007-61254) Ministerio de Educación y Ciencia (Nacional) 7.260,00 €
13/12/2004 13/12/2007 Nuevas metodologías para la síntesis de inhibidores enzimáticos específicos, prolinas polifuncionales y peptidomiméticos (CTQ2004-00649) Ministerio de Ciencia y Tecnología (Nacional) 58.650,00 €
01/01/2004 30/06/2007 Targeting Replication and Integration of HIV (TRIoH) (LSHB-CT-2003-503480) Commission of the European Communities (Europeo) 251.500,00 €
28/12/2001 27/09/2005 Síntesis estereocontroladas de iminociclitoles, de N- y C-glicósidos y de (tio, seleno) carbomoil azúcares de interés biológico a partir de aminoazúcares y de sulfatos cíclicos (BQU2001-3740) Ministerio de Ciencia y Tecnología (Nacional) 117.167,28 €
28/12/2001 27/12/2004 Miméticos de biomoléculas. Nuevas síntesis, nuevas metodologías, nuevos fármacos (BQU2001-3779) Ministerio de Ciencia y Tecnología (Nacional) 34.558,18 €

Contratos

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
21/10/2010 20/10/2012 Estrategias de utilización de ingredientes (minerales y de nueva síntesis) para mejorar la salud intestinal de los lechones al destete. (0903/0400) Universidad Autónoma de Barcelona (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/05/2010 30/10/2011 Integrating chemical approaches to treat pancreatic cancer (CTQ2010-10812-E) Ministerio de Ciencia e Innovación (Nacional) 1.900,00 €
01/01/2006 01/01/2007 Targeting replication and integration of hiv (SAF2004-22949-E) Ministerio de Educación y Ciencia (Nacional) 5.500,00 €
30/12/2003 30/12/2004 Targeting replication and integration of HIV (BQU2002-11790-E) Ministerio de Ciencia y Tecnología (Nacional) 6.000,00 €

Infraestructura

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/01/2013 31/12/2015 Nuevo equipamiento de laboratorio para la síntesis, purificación y análisis de compuesto orgánico (UNSE13-1E-2032) Ministerio de Economía y Competitividad (Europeo) 112.012,41 €

Patentes

Nº Solicitud Fecha Solicitud Fecha Concesión Nombre
P200703050 14/11/2007 25/01/2010 Tiofucosidos conteniendo polihidroxialquil-furanos. Síntesis y usos de los mismos
P200703049 14/11/2007 25/01/2010 Tiofucosidos conteniendo prolinas hidroxiladas. Síntesis y usos de los mismos.