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Ver Investigador - - Prisma - Unidad de Bibliometría

Emilio Fernández Espejo

Catedrático de Universidad
efespejo@us.es

Investiga en

Palabras clave
Líneas de investigación
Resumen
Tipo Año Título Fuente
Artículo2022 Myeloperoxidase and Advanced Oxidation Protein Products in the Cerebrospinal Fluid in Women and Men with Parkinson’s Disease ANTIOXIDANTS
Artículo2022 Salivary ATP13A2 is a potential marker of therapy-induced motor complications and is expressed by inclusions in submandibulary glands in Parkinson's disease Clinical Parkinsonism & Related Disorders
Artículo2021 A cross-sectional study of foot growth and its correlation with anthropometric parameters in a representative cohort of schoolchildren from Southern Spain. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
Artículo2021 Cerebrospinal fluid lactoperoxidase level is enhanced in idiopathic Parkinson's disease, and correlates with levodopa equivalent daily dose BRAIN RESEARCH
Artículo2020 A rare paronychia with superinfection with prevotella bivia and staphylococcus haemolyticus: the importance of early microbiological diagnosis Pathogens
Revisión2019 Endocannabinoid-mediated synaptic plasticity and substance use disorders NEUROLOGIA
Revisión2019 Is there a halo-enzymopathy in Parkinson's disease? NEUROLOGIA
Artículo2018 Analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly EXPERIMENTAL GERONTOLOGY
Artículo2018 Excess amounts of 3-iodo-L-tyrosine induce Parkinson-like features in heck tor experimental approaches of Parkinsonism NEUROTOXICOLOGY
Artículo2018 Oleoylethanolamide and Palmitoylethanolamide Protect Cultured Cortical Neurons Against Hypoxia Cannabis and Cannabinoid Research
Artículo2018 Palmitoylethanolamide prevents neuroinflammation, reduces astrogliosis and preserves recognition and spatial memory following induction of neonatal anoxia-ischemia PSYCHOPHARMACOLOGY
Artículo2015 Does the Cerebrospinal Fluid Reflect Altered Redox State But Not Neurotrophic Support Loss in Parkinson's Disease? ANTIOXIDANTS & REDOX SIGNALING
Artículo2015 Effects of acute and repeated cocaine on markers for neural plasticity within the mesolimbic system in rats PSYCHOPHARMACOLOGY
Artículo2015 The transient receptor potential vanilloid-1 is localized at excitatory synapses in the mouse dentate gyrus BRAIN STRUCTURE & FUNCTION
Artículo2014 May the Thyroid Gland and Thyroperoxidase Participate in Nitrosylation of Serum Proteins and Sporadic Parkinson's Disease? ANTIOXIDANTS & REDOX SIGNALING
Artículo2014 The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
Ponencia2013 Cerebrospinal fluid and serum from Parkinsonian patients are cytotoxic for dopamine neurons and serum nitro-alpha-synuclein could participate in Parkinsonian damage JOURNAL OF NEUROLOGY
Artículo2013 May Serum Levels of Advanced Oxidized Protein Products Serve as a Prognostic Marker of Disease Duration in Patients with Idiopathic Parkinson's Disease? ANTIOXIDANTS & REDOX SIGNALING
Artículo2013 May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum -Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease? ANTIOXIDANTS & REDOX SIGNALING
Artículo2013 Oleoylethanolamide dose-dependently attenuates cocaine-induced behaviours through a PPARa receptor-independent mechanism ADDICTION BIOLOGY
Artículo2012 Alteration of neuropathic and visceral pain in female C57BL/6J mice lacking the PPAR-alpha gene PSYCHOPHARMACOLOGY
Ponencia2012 Neuroprotective Role For Acylethanolamides On Brain Injury, Neuroinflammation And Neurodegeneration BRAIN INJURY
Corrección2012 Sensitization to cocaine is inhibited after intra-accumbal GR103691 or rimonabant, but it is enhanced after co-infusion indicating functional interaction between accumbens D-3 and CB1 receptors (vol 214, pg 949, 2011) PSYCHOPHARMACOLOGY
Artículo2011 MICE LACKING THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA GENE PRESENT REDUCED NUMBER OF DOPAMINE NEURONS IN THE SUBSTANTIA NIGRA WITHOUT ALTERING MOTOR BEHAVIOR OR DOPAMINE NEURON DECLINE OVER LIFE NEUROSCIENCE
Revisión2011 Psychostimulant Drugs and Neuroplasticity PHARMACEUTICALS
Artículo2011 Sensitization to cocaine is inhibited after intra-accumbal GR103691 or rimonabant, but it is enhanced after co-infusion indicating functional interaction between accumbens D-3 and CB1 receptors PSYCHOPHARMACOLOGY
Artículo2010 Antiparkinsonian trophic action of glial cell line-derived neurotrophic factor and transforming growth factor beta 1 is enhanced after co-infusion in rats EXPERIMENTAL NEUROLOGY
Artículo2010 Effects of the Endogenous PPAR-alpha Agonist, Oleoylethanolamide on MDMA-Induced Cognitive Deficits in Mice SYNAPSE
Artículo2010 Exposure to Cry protoxins induces oxidative stress, dopamine neuron death, and intraneuronal a-synuclein-positive inclusions in the substantia nigra of rats Journal Of Neurodegeneration & Regeneration
Artículo2010 FIBROBLAST GROWTH FACTOR-1 WITHIN THE VENTRAL TEGMENTAL AREA PARTICIPATES IN MOTOR SENSITIZING EFFECTS OF MORPHINE NEUROSCIENCE
Artículo2010 INTRA-ACCUMBENS RIMONABANT IS REWARDING BUT INDUCES AVERSION TO COCAINE IN COCAINE-TREATED RATS, AS DOES IN VIVO ACCUMBAL CANNABINOID CB1 RECEPTOR SILENCING: CRITICAL ROLE FOR GLUTAMATE RECEPTORS NEUROSCIENCE
Artículo2010 Morphophysiology of the Zuckerkandl's paraganglion: Effects of dexamethasone and aging NEUROBIOLOGY OF AGING
Artículo2010 Response to methadone maintenance treatment is associated with the MYOCD and GRM6 genes MOLECULAR DIAGNOSIS & THERAPY
Ponencia2009 Effects of Aging in Extra-adrenal Paraganglia, and in Extra-adrenal Chromaffin Cell Transplants in Parkinsonian Rats HUMAN GENE THERAPY
Ponencia2009 Improved trophic efficacy of glial cell-derived neurotropic factor (GDNF) after combination with TGF-beta 1 both in vitro and in vivo models of parkinsonism EUROPEAN NEUROPSYCHOPHARMACOLOGY
Artículo2009 Oleoylethanolamide exerts partial and dose-dependent neuroprotection of substantia nigra dopamine neurons NEUROPHARMACOLOGY
Ponencia2009 Presence of Progenitor Cells in Extraadrenal Chromaffin Tissue Belonging to the Sympathoadrenal Lineage HUMAN GENE THERAPY
Revisión2009 Role of cannabis and endocannabinoids in the genesis of schizophrenia PSYCHOPHARMACOLOGY
Artículo2009 THE ABSENCE OF A FUNCTIONAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA GENE IN MICE ENHANCES MOTOR SENSITIZING EFFECTS OF MORPHINE, BUT NOT COCAINE NEUROSCIENCE
Artículo2008 Expression and function of CB1 receptor in the rat striatum: Localization and effects on D-1 and D-2 dopamine receptor-mediated motor behaviors NEUROPSYCHOPHARMACOLOGY
Artículo2008 Grafts of extra-adrenal chromaffin cells as aggregates show better survival rate and regenerative effects on parkinsonian rats than dispersed cell grafts NEUROBIOLOGY OF DISEASE
Artículo2008 Role for D-Serine within the ventral tegmental area in the development of cocaine's sensitization NEUROPSYCHOPHARMACOLOGY
Artículo2007 Cannabinoid CB1 receptor antagonism markedly increases dopamine receptor-mediated stereotypies EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2006 QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine NEUROPHARMACOLOGY
Artículo2006 Role for dopamine neurons of the rostral linear nucleus and periaqueductal gray in the rewarding and sensitizing properties of heroin NEUROPSYCHOPHARMACOLOGY
Artículo2006 The neurobiology of psychostimulant addiction REVISTA DE NEUROLOGIA
Artículo2005 Acute Delta(9)-tetrahydrocannabinol exposure facilitates quinpirole-induced hyperlocomotion PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Artículo2005 Cannabinoid CB1 antagonists possess antiparkinsonian efficacy only in rats with very severe nigral lesion in experimental parkinsonism NEUROBIOLOGY OF DISEASE
Artículo2005 Cells of the sympathoadrenal lineage: Biological properties as donor tissue for cell-replacement therapies for Parkinson's disease BRAIN RESEARCH REVIEWS
Artículo2004 Effects on turning of microinjections into basal ganglia of D-1 and D-2 dopamine receptors agonists and the cannabinoid CB1 antagonist SR141716A in a rat Parkinson's model NEUROBIOLOGY OF DISEASE
Artículo2004 Experimental Parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: A modulator of endocannabinoid function NEUROPSYCHOPHARMACOLOGY
Artículo2004 Opiate anti-nociception is attenuated following lesion of large dopamine neurons of the periaqueductal grey: critical role for D-1 (not D-2) dopamine receptors PAIN
Artículo2004 Pathogenesis of Parkinson's disease - prospects of neuroprotective and restorative therapies MOLECULAR NEUROBIOLOGY
Artículo2004 Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor PSYCHOPHARMACOLOGY
Artículo2003 Changes in dopaminergic neurotransmission do not alter somatic or motivational opiate withdrawal-induced symptoms in rats BEHAVIORAL NEUROSCIENCE
Artículo2003 Inhibition of 5-HT neurotransmission increases clonidine protective effects on naloxone-induced conditioned place aversion in morphine-dependent rats NEUROPSYCHOPHARMACOLOGY
Artículo2003 Natural 'dopaminotrophic' cell transplant: A new concept in antiparkinsonian therapy REVISTA DE NEUROLOGIA
Artículo2003 Prefrontocortical dopamine loss in rats delays long-term extinction of contextual conditioned fear, and reduces social interaction without affecting short-term social interaction memory NEUROPSYCHOPHARMACOLOGY
Artículo2002 Dorsal and median raphe serotonergic system lesion does not alter the opiate withdrawal syndrome PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Artículo2002 Neurobiological basis of drug addiction REVISTA DE NEUROLOGIA
Artículo2001 Adrenergic hyperactivity and metanephrine excess in the nucleus accumbens after prefrontocortical dopamine depletion JOURNAL OF NEUROPHYSIOLOGY
Artículo2001 Behavioral expression of opiate withdrawal is altered after prefrontocortical dopamine depletion in rats: Monoaminergic correlates NEUROPSYCHOPHARMACOLOGY
Artículo2001 Functional regeneration in a rat Parkinson's model after intrastriatal grafts of glial cell line-derived neurotrophic factor and transforming growth factor β1-expressing extra-adrenal chromaffin cells of the Zuckerkandl's organ JOURNAL OF NEUROSCIENCE
Revisión2000 How does the nucleus accumbens tick? REVISTA DE NEUROLOGIA
Artículo2000 Is the fundus striati a new limbic-motor interphase? REVISTA DE NEUROLOGIA
Artículo2000 Naloxone-induced opiate withdrawal produces long-lasting and context-independent changes in aggressive and social behaviors of postdependent male mice BEHAVIORAL NEUROSCIENCE
Artículo1999 Behavioral sensitization to cocaine after a brief social defeat stress: c-fos expression in the PAG PSYCHOPHARMACOLOGY
Artículo1999 Prefrontocortical dopamine depletion induces antidepressant-like effects in rats and alters the profile of desipramine during Porsolt's test NEUROSCIENCE
Artículo1999 Total neurochemical lesion of noradrenergic neurons of the locus ceruleus does not alter either naloxone-precipitated or spontaneous opiate withdrawal nor does it influence ability of clonidine to reverse opiate withdrawal JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Artículo1998 Antagonism of peripheral 5-HT4 receptors reduces visceral and cutaneous pain in mice, and induces visceral analgesia after simultaneous inactivation of 5-HT3 receptors BRAIN RESEARCH
Ponencia1998 Anxiety is enhanced after selective dopamine depletion within the medial prefrontal cortex of rats EUROPEAN JOURNAL OF NEUROSCIENCE
Artículo1998 Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantation of carotid body cell aggregates NEURON
Ponencia1998 Neuroprotective effect of salicylic acid in the MPTP model of Parkinson's disease in mice EUROPEAN JOURNAL OF NEUROSCIENCE
Artículo1997 Effects of weekly or daily exposure to the elevated plus-maze in male mice BEHAVIOURAL BRAIN RESEARCH
Artículo1997 Selective dopamine depletion within the medial prefrontal cortex induces anxiogenic-like effects in rats placed on the elevated plus maze BRAIN RESEARCH
Artículo1997 Single restraint stress sensitizes acute chewing movements induced by haloperidol, but not if the 5-HT1A agonist 8-OH-DPAT is given prior to stress BRAIN RESEARCH
Artículo1997 Structure of the mouse behaviour on the elevated plus-maze test of anxiety BEHAVIOURAL BRAIN RESEARCH
Artículo1995 ETHOPHARMACOLOGICAL ANALYSIS OF NALOXONE-PRECIPITATED MORPHINE-WITHDRAWAL SYNDROME IN RATS - A NEWLY DEVELOPED ETHO-SCORE PSYCHOPHARMACOLOGY
Nota1994 DIFFERENTIAL-EFFECTS OF WEEKLY AND DAILY EXPOSURE TO THE HOT PLATE ON THE RATS BEHAVIOR PHYSIOLOGY & BEHAVIOR
Artículo1994 EFFECTS OF MORPHINE AND NALOXONE ON BEHAVIOR IN THE HOT PLATE TEST - AN ETHOPHARMACOLOGICAL STUDY IN THE RAT PSYCHOPHARMACOLOGY
Artículo1993 STRUCTURE OF THE RATS BEHAVIOR IN THE HOT PLATE TEST BEHAVIOURAL BRAIN RESEARCH
Ponencia1992 MORPHINE AND NALOXONE-INDUCED BEHAVIORAL-CHANGES IN RATS PLACED ON THE HOT PLATE EUROPEAN JOURNAL OF NEUROSCIENCE
Artículo1990 BEHAVIORAL-STUDY IN RATS OF PAIRED ACCUMBENS-LESIONED RESIDENTS AND INTACT INTRUDERS PHYSIOLOGY & BEHAVIOR
Artículo1990 ETHOLOGICAL ANALYSIS OF THE MALE-RATS SOCIOAGONISTIC BEHAVIOR IN A RESIDENT-INTRUDER PARADIGM AGGRESSIVE BEHAVIOR
Letter1988 HEMODYNAMIC ARTERIOVENOUS FISTULA MONITORING, USING THE FRANCESCHI-LUIZY DOPPLER-METHOD NEFROLOGIA
Tesis dirigidas/tutorizadas:9
Fecha lectura Título Rol
16/05/2019 FACTORES NEUROTRÓFICOS Y ANTIOXIDANTES EN LÍQUIDO CEFALORRAQUÍDEO DURANTE EL ENVEJECIMIENTO NORMAL O CON DETERIORO COGNITIVO LEVE Y EN LA ENFERMEDAD DE PARKINSON Director/a
15/06/2012 ESTUDIOS DE EFECTOS NEUROBIOLÓGICOS DEL DELTA-9-TETRAHIDROCANNABIOL EN MODELOS ANIMALES Director/a
13/07/2011 ESTUDIO MORFOFUNCIONAL DEL ÓRGANO DE ZUCKERKANDL EN LA RATA (RATTUS NORVEGICUS) Director/a
18/03/2011 NEUROPROTECCIÓN EN MODELOS DE PARKINSONISMO: EFECTOS DEL ANÁLOGO CANNABINOIDE OLEILETANOLAMIDA (OEA) Y DE LOS FACTORES TRÓFICOS DERIVADOS DE LA GLÍA (GDNF) Y TRANSFORMANTE BETA-1(TGF-B1) Director/a
03/12/2010 PAPEL DE LOS RECEPTORES CB1 Y D3 MESOLÍMBICOS Y CAMBIOS NEUROPLÁSTICOS EN LA ADICCIÓN A COCAÍNA EN RATAS Director/a
02/10/2007 Terapia experimental en modelos animales de disfunción dopaminérgica Director/a
09/11/2005 ESTUDIOS SOBRE EL PAPEL DEL ÁREA TEGMENTAL VENTRAL Y DE LAS REGIONES DOPAMINÉRGICAS ROSTRAL LINEAL Y PERIACUEDUCTAL DEL MESENCÉFALO EN LA ADICCIÓN Y ANALGESIA OPIÁCEAS EN RATAS Director/a
21/06/2004 EVALUACIÓN DE NUEVAS TERAPIAS BASADAS EN TRASPLANTE EXTRAADRENAL Y FÁRMACOS CANNABINOIDES EN UN MODELO ANIMAL DE LA ENFERMEDAD DE PARKINSON Director/a
15/03/2004 EFICACIA ANTIPARKINSONIANA DE LIGANDOS CANNABINOIDES DEL RECEPTOR CB1 EN UN MODELO ANIMAL DE LA ENFERMEDAD DE PARKINSON Director/a

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/12/2002 01/12/2005 Responsable Estudio de la eficacia antiparkinsoniana del trasplante celular del paraganglio de zuckerkandl y de las características electrofisiológicas de las células paraganglionares (SAF2002-01689) Ministerio de Ciencia y Tecnología (Nacional)
13/04/2007 12/04/2010 Responsable Estudio de la eficacia neurotrófica y regenerativa de trasplantes de células cromafines extraadrenales en parkinsonismo animal (P06-CTS-01716) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico)
01/01/2009 31/12/2011 Responsable Terapia neurotrófica antiparkinsoniana con células cromafines extraadrenales y búsqueda de células progenitoras (BFU2008-01060) Ministerio de Ciencia e Innovación (Nacional)
26/10/2009 25/10/2012 Responsable Estudio sobre la D-serina como nuevo mediador de psicosis cocaínica, y de los cambios plásticos neuronales inducidos por la cocaína crónica (PND2009-001) Ministerio de Sanidad y Política Social (Nacional)
28/12/2004 30/12/2007 Responsable Estudio de papel de los factores neurotróficos FGF-1 y ALFA del área tegmental ventral en la adicción a drogas (PI040155) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional)
01/01/2003 21/06/2006 Responsable Investigación sobre las bases biológicas de la adicción, su terapéutica y su repercución sobre la salud pública (G03/005) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional)
23/12/2005 23/12/2006 Responsable Red de trastornos adictivos: Neurobiología de opiáceos y aminas biógenas (PI051493) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional)
15/01/2007 15/07/2010 Responsable Estudio de nuevas dianas terapéuticas para el desarrollo de fármacos neuroprotectores (CONVFM2007-001) La Fundació La Marató de TV3 (Nacional)
27/10/2005 27/10/2008 Responsable Estudio sobre el potencial psicótico del cannabis (PNSD05/002) Ministerio de Sanidad y Consumo (Nacional)
01/02/2012 31/01/2015 Investigador/a Evaluación de neuroprotectores basados en aciletanolamidas en modelos animales de hipóxia cerebral perinatal y adulta (CNPMA/MAT/055) La Fundació La Marató de TV3 (Nacional)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/04/2001 01/04/2004 Responsable Estudio de la eficacia antiparkinsoniana de ligandos cannabinoides (SI-029/01) Laboratorios del Dr. Esteve, S.A. (Desconocido)
01/05/2015 30/04/2020 Responsable COPPADIS-2015 (Cohort of Patients with Parkinsons´s DIsease in Spain, 2015). (2506/0770) Fundación Fuertes (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
11/11/2011 11/11/2011 Responsable III Encuentro de Neurociencia y Neurología sobre Enfermedades Neurodegenerativas (PP2011-01-047) Universidad de Sevilla (Local)
18/10/2015 17/10/2016 Responsable Estudios sobre PARK9 (ATP13A2) en enfermos de Parkinson Idiopático (SUBAIA2015/006) Sociedad Andaluza de Neurología (Autonómico)

Redes de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2007 31/12/2013 Responsable Ayuda para la financiación de investigación en el área de biomedicina y ciencia de la salud (RD06/0001/0002) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional)
16/02/2008 31/12/2014 Responsable Red de terapia celular. (RD06/0010/1007) Ministerio de Ciencia e Innovación (Nacional)
El investigador no tiene ningún resultado de investigación asociado