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Antonio Perez Perez

Profesor Titular de Universidad (Pza. V)
aperez14@us.es
Área de conocimiento: Bioquímica y Biología Molecular
Departamento: Bioquímica Médica y Biología Molecular e Inmunología
Grupo: BIOQUIMICA MEDICA - CTS-151 (Universidad de Sevilla)
Prog. doctorado: BIOLOGÍA MOLECULAR, BIOMEDICINA E INVESTIGACIÓN CLÍNICA

Investiga en

Tipo Año Título Fuente
Revisión2024 Impact of obesity‑associated myeloid‑derived suppressor cells on cancer risk and progression (Review) INTERNATIONAL JOURNAL OF ONCOLOGY
Revisión2024 Increasing the complexity of lipoprotein characterization for cardiovascular risk in type 2 diabetes EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
Artículo2024 Influence of the Surface Topography of Titanium Dental Implants on the Behavior of Human Amniotic Stem Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2024 Influencia de la presencia y tipo de enfermedad cardiovascular sobre el riesgo de mortalidad de los pacientes con diabetes tipo 2: estudio DIABET-IC Endocrinología, diabetes y nutrición
Artículo2024 Lipid-lowering drug therapy for reducing cardiovascular risk in diabetes. A clinical view of the Cardiovascular Disease Working Group of the Spanish Diabetes Society Endocrinología, diabetes y nutrición
Artículo2024 Placental apoptosis increased by hypoxia inducible factor-1 stabilization is counteracted by leptin† BIOLOGY OF REPRODUCTION
Artículo2024 Role of leptin in obesity, cardiovascular disease, and type 2 diabetes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Capítulo2024 Simplified acid extraction and quantification of histones in human tumor cells Methods in Cell Biology
Capítulo2024 Simplified acid extraction and quantification of histones in human tumor cells Methods in Cell Biology
Artículo2024 Study of the diagnostic efficiency of anti-ZnT8 autoantibodies for type 1 diabetes in pediatric patients LABORATORY MEDICINE
Artículo2024 Terapia farmacológica hipolipemiante para la reducción del riesgo cardiovascular en la diabetes. Visión clínica del Grupo de Trabajo de Enfermedad Cardiovascular de la Sociedad Española de Diabetes Endocrinología, diabetes y nutrición
Artículo2024 Tissue‐specific early and late activated lymphocytes immunophenotype in chronic rhinosinusitis with nasal polyps International Forum of Allergy and Rhinology
Artículo2023 Circulating myeloid-derived suppressor cells may be a useful biomarker in the follow-up of unvaccinated COVID-19 patients after hospitalization FRONTIERS IN IMMUNOLOGY
Artículo2023 Consensus document for lipid profile testing and reporting in Spanish clinical laboratories: what parameters should a basic lipid profile include? Advances in Laboratory Medicine
Artículo2023 Documento de consenso para la determinación e informe del perfil lipídico en laboratorios clínicos españoles Advances in Laboratory Medicine
Artículo2023 Documento de consenso para la determinación e informe del perfil lipídico en laboratorios clínicos españoles ¿Qué parámetros debe incluir un perfil lipídico básico? REVISTA CLINICA ESPANOLA
Artículo2023 Expression of nutrient transporters in placentas affected by gestational diabetes: role of leptin Frontiers in Endocrinology
Artículo2023 Human amniotic epithelial stem cells: Hepatic differentiation and regenerative properties in liver disease treatment. PLACENTA
Artículo2023 Statement of the Spanish Interdisciplinary Vascular Prevention Committee on the updated European Guidelines on Cardiovascular Disease Prevention NEFROLOGIA
Artículo2023 The HLA-DQA1*05 genotype does not influence the clinical response to ustekinumab and vedolizumab. Revista Española de Enfermedades Digestivas
Artículo2022 Decreased expression of Sam68 is associated with insulin resistance in granulosa cells from PCOS patients Cells
Resumen congreso2022 Human amniotic epithelial stem cells: involvement of WNT/ΒETA-catenin signalling during their hepatic differentiation PLACENTA
Revisión2022 Leptin in dental pulp and periapical tissues: a narrative review INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2022 Low levels of granulocytic myeloid-derived suppressor cells may be a good marker of survival in the follow-up of patients with severe COVID-19 FRONTIERS IN IMMUNOLOGY
Resumen congreso2022 Mechanisms involved in leptin antiapoptotic effect after HIF-1 alpha stabilization PLACENTA
Artículo2022 Obesity and risk for lymphoma: possible role of leptin. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Revisión2022 Obesity as a risk factor for dementia and Alzheimer’s disease: the role of leptin INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Resumen congreso2022 Pro-apoptotic effect of amniotic membrane conditioned medium in hepatocarcinoma cells PLACENTA
Artículo2021 Comparison of the analytical and clinical performances of two different routine testing protocols for antinuclear antibody screening JOURNAL OF CLINICAL LABORATORY ANALYSIS
Revisión2021 Leptin, both bad and good actor in cancer BIOMOLECULES
Revisión2021 Nutritional modulation of leptin expression and leptin action in obesity and obesity-associated complications JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Revisión2021 Stem cells and COVID-19: are the human amniotic cells a new hope for therapies against the SARS-CoV-2 virus? Stem cell research & therapy
Capítulo2020 Aquaporins and placenta Aquaporin regulation
Artículo2020 Crosstalk between estradiol and NFκB signaling pathways on placental leptin expression REPRODUCTION
Artículo2020 Leptin and nutrition in gestational diabetes NUTRIENTS
Revisión2020 Role of leptin in inflammation and vice versa INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2020 Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS ENDOCRINE CONNECTIONS
Artículo2019 Circulating regulatory T cells from breast cancer patients in response to neoadjuvant chemotherapy TRANSLATIONAL CANCER RESEARCH
Artículo2019 Human amniotic membrane conditioned medium inhibits proliferation and modulates related microRNAs expression in hepatocarcinoma cells Scientific reports
Artículo2019 Leptin protects placental cells from apoptosis induced by acidic stress CELL AND TISSUE RESEARCH
Artículo2019 Leptin stimulates DMP-1 and DSPP expression in human dental pulp via MAPK 1/3 and PI3K signaling pathways ARCHIVES OF ORAL BIOLOGY
Revisión2019 Obesity and Breast Cancer: Role of Leptin FRONTIERS IN ONCOLOGY
Ponencia2019 Role of leptin on the apoptosis of trophoblast explants triggered by acidosis PLACENTA
Revisión2018 Involvement of leptin in the molecular physiology of the placenta REPRODUCTION
Revisión2018 Leptin action in normal and pathological pregnancies JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Artículo2018 Leptin upregulates aquaporin 9 expression in human placenta in vitro GYNECOLOGICAL ENDOCRINOLOGY
Artículo2018 Placental leptin expression is mediated by NFκB signaling PLACENTA
Artículo2018 Proliferation and survival of human amniotic epithelial cells during their hepatic differentiation PLOS ONE
Capítulo2017 Action and Mechanisms of Action of the Chromogranin A Derived Peptide Pancreastatin Chromogranins: from Cell Biology to Physiology and Biomedicine
Resumen congreso2017 HUMAN AMNIOTIC EPITHELIAL CELLS: EVALUATION OF SURVIVAL DURING THEIR HEPATIC DIFFERENTIATION PLACENTA
Revisión2017 Role of leptin as a link between metabolism and the immune system CYTOKINE & GROWTH FACTOR REVIEWS
Resumen congreso2017 ROLE OF LEPTIN IN THE MOLECULAR PHYSIOLOGY OF THE PLACENTA PLACENTA
Artículo2017 Sp1 transcription factor is a modulator of estradiol leptin induction in placental cells PLACENTA
Resumen congreso2017 TRANSCRIPTION FACTORS INVOLVED IN ESTRADIOL LEPTIN INDUCTION IN PLACENTA PLACENTA
Artículo2016 Increased Expression of Aquaporin 9 in Trophoblast From Gestational Diabetic Patients HORMONE AND METABOLIC RESEARCH
Artículo2016 Insulin and Leptin Signaling in Placenta from Gestational Diabetic Subjects HORMONE AND METABOLIC RESEARCH
Artículo2016 Leptin reduces apoptosis triggered by high temperature in human placental villous explants: The role of the p53 pathway PLACENTA
Capítulo2016 Pancreastatin signaling. mechanisms of action The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Capítulo2016 Pancreastatin, a regulatory peptide derived from chromogranin A The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Artículo2016 Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells PLOS ONE
Ponencia2015 Antiapoptotic effects of leptin on trophoblasts PLACENTA
Artículo2015 Evaluation of a HbA1c point-of-care analyzer CLINICAL BIOCHEMISTRY
Artículo2015 Expression and immunohistochemical localization of leptin in human periapical granulomas Medicina oral, patología oral y cirugía bucal
Artículo2015 Expression and immunohistochemical localization of leptin receptor in human periapical granuloma INTERNATIONAL ENDODONTIC JOURNAL
Ponencia2015 Human amniotic epithelial cells: Proliferation and apoptosis during their hepatic differentiation PLACENTA
Ponencia2015 Leptin is involved in human trophoblast migration and invasion PLACENTA
Artículo2015 Leptin Promotes Dentin Sialophosphoprotein Expression in Human Dental Pulp JOURNAL OF ENDODONTICS
Artículo2015 Mechanisms involved in p53 downregulation by leptin in trophoblastic cells PLACENTA
Revisión2015 Role of leptin in female reproduction CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Corrección2014 Correction: Leptin Is an Anti-Apoptotic Effector in Placental Cells Involving p53 Downregulation (vol 9, e99187, 2014) PLOS ONE
Artículo2014 Leptin Is an anti-apoptotic effector in placental cells involving p53 downregulation PLOS ONE
Artículo2013 Activated Translation Signaling in Placenta from Pregnant Women with Gestational Diabetes Mellitus: Possible Role of Leptin HORMONE AND METABOLIC RESEARCH
Artículo2013 Effective treatment of pulmonary tuberculosis restores plasma leptin levels EUROPEAN CYTOKINE NETWORK
Artículo2013 Insulin enhances leptin expression in human trophoblastic cells BIOLOGY OF REPRODUCTION
Capítulo2013 Leptin action and leptin receptor signaling in human trophoblasts The Placenta: Development, Function and Diseases
Artículo2013 Leptin expression in healthy and inflamed human dental pulp INTERNATIONAL ENDODONTIC JOURNAL
Artículo2013 Leptin Receptor Is Up-regulated in Inflamed Human Dental Pulp JOURNAL OF ENDODONTICS
Artículo2012 Elsevier Trophoblast Research Award Lecture: Molecular mechanisms underlying estrogen functions in trophoblastic cells - Focus on leptin expression PLACENTA
Artículo2012 Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo2012 The Alternative Epac/cAMP Pathway and the MAPK Pathway Mediate hCG Induction of Leptin in Placental Cells PLOS ONE
Artículo2011 Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells MOLECULAR AND CELLULAR ENDOCRINOLOGY
Artículo2011 Review: Leptin gene expression in the placenta - Regulation of a key hormone in trophoblast proliferation and survival PLACENTA
Capítulo2011 Role of leptin in the activation of the immune system Leptin: Hormonal Functions, Dysfunctions and Clinical Uses
Artículo2011 Sam68 mediates leptin-stimulated growth by modulating leptin receptor signaling in human trophoblastic JEG-3 cells HUMAN REPRODUCTION
Artículo2010 17Beta-Estradiol Enhances Leptin Expression in Human Placental Cells Through Genomic and Nongenomic Actions BIOLOGY OF REPRODUCTION
Artículo2010 MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Revisión2010 Role of Leptin in the Activation of Immune Cells MEDIATORS OF INFLAMMATION
Artículo2009 Leptin Stimulates Protein Synthesis-Activating Translation Machinery in Human Trophoblastic Cells BIOLOGY OF REPRODUCTION
Artículo2009 Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Artículo2008 Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
05/10/2021 31/03/2023 Investigador/a Regulación Inmunometabólica por la Leptina del eje Células Dendríticas-Células iNKT, y su posible Papel en la Diabetes Gestacional (P20_01253) Junta de Andalucía (Consejería de Economía, Conocimiento, Empresas y Universidad) (Autonómico)
01/02/2020 30/04/2022 Investigador/a Descifrando el papel de los ácidos grasos de la dieta sobre la funcionalidad de las HDL (US-1263458) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)
05/05/2011 31/12/2014 Contratado Investigación sobre nuevos marcadores de valoración embrionaria (IPT-2011-1488-900000) Ministerio de Ciencia e Innovación (Nacional)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
25/09/2024 24/09/2025 Investigador/a La Valoración del Comportamiento y Desarrollo de Las Células Madre Humanas en distintos Materiales Dentales (5249/2086) Nueva Galimplant SLU (Desconocido)
El investigador no tiene ningún resultado de investigación asociado