Internal student in 1993 in the Department of Physical Chemistry of the Faculty of Chemistry at the University of
Seville. Collaboration grant to carry out research tasks, 1994. In 1995 I got the Extraordinary Degree Award from
the 90/95 class. I obtained a Camara Scholarship (homologated scholarship awarded to the best record of each
faculty) to carry out the Doctoral Thesis (1996-1999) and various awards from the Excellency of Seville City
Council and the Real Maestranza de Caballeria. Doctor in Chemistry, 1999, 'Electron transfer reactions in micellar
systems', published in journals such as Langmuir, PCCP, New J. Chem or Coordination Chemistry Reviews. At
the same time, I started my Pharmacy degree, obtaining an Honors Degree in Parasitology and obtaining my first
contract as Associate Professor of the Department of Physical Chemistry in 1999. After being invited to give a
conference in France on electronic transfers, to apply for a contract postdoctoral, I did a two-year stay (2000 and
2001), hired by the CNRS and the U.E. in Montpellier (France), at the Center of Biochemie Structurale and at the
Institut für Mikrobiologieund Genetik, Vienna (Austria). My research work focused on the synthesis of fluorescent
DNA and RNA and the application of pulse NMR to the conformational study of proteins and DNA. As a result
of this stay, I published in first quartile journals, Phytomedicine or J. Ethnopharmacology, highlighting the
publication in Nature Biotechnology (first in IF in this field, 39) of a conformational study, by means of pulse
NMR, of a protein that inhibits entry of the HIV virus. I rejoined the U. Sevilla where I currently carry out my
teaching and research work. The latter, initially, were directed to the study of reactivity changes in restricted
geometry systems (DNA; polypeptides;) taking advantage of the learning of my postdoctoral stay. As of 2003 and
after working at the New Center for Scientific Research of La Isla de la Cartuja (CICIC), my research continues
to focus on the interaction of biomolecules with systems of restricted geometry, but already with nanoparticles. As
a result of this, I directed a Doctoral Thesis during this period, giving rise to various publications in first quartile
journals where the interaction of DNA with gold nanoparticles, AuNPs, was analyzed in detail. Likewise, the
analysis of aluminum or gold nanoparticles with small ligands has been published in PCCP or J. Phys. Chem. C. I
have recently published both reviews and book chapters focused on the surface recognition of DNA by AuNPs.
Currently my research deals with the interactions of proteins and DNA with AuNPs, optimizing these from a
kinetic and thermodynamic point of view. On the other hand, the obtaining in 2011 and 2013 of two invention
patents in the field of bionanomedicine and a third in 2016 for the detection in urine by AuNPs of a protein such
as lysozyme, linked to leukemia, allows me to collaborate with staff of the Virgen Macarena Hospital in Seville
to continue studying the potential use of AuNPs as biopolymer biosensors. At the age of 51, more than 101
publications, including books, book chapters, articles and patents and more than 54 participations in congresses
certify my research work, being the PI responsible for the FQM 386 Group “Synthesis and Physicochemistry of
Nanoparticles”. I reached the category of full professor (Catedrático) at the physical chemistry department of the
University of Sevilla in 2023.
Internal student in 1993 in the Department of Physical Chemistry of the Faculty of Chemistry at the University of
Seville. Collaboration grant to carry out research tasks, 1994. In 1995 I got the Extraordinary Degree Award from
the 90/95 class. I obtained a Camara Scholarship (homologated scholarship awarded to the best record of each
faculty) to carry out the Doctoral Thesis (1996-1999) and various awards from the Excellency of Seville City
Council and the Real Maestranza de Caballeria. Doctor in Chemistry, 1999, 'Electron transfer reactions in micellar
systems', published in journals such as Langmuir, PCCP, New J. Chem or Coordination Chemistry Reviews. At
the same time, I started my Pharmacy degree, obtaining an Honors Degree in Parasitology and obtaining my first
contract as Associate Professor of the Department of Physical Chemistry in 1999. After being invited to give a
conference in France on electronic transfers, to apply for a contract postdoctoral, I did a two-year stay (2000 and
2001), hired by the CNRS and the U.E. in Montpellier (France), at the Center of Biochemie Structurale and at the
Institut für Mikrobiologieund Genetik, Vienna (Austria). My research work focused on the synthesis of fluorescent
DNA and RNA and the application of pulse NMR to the conformational study of proteins and DNA. As a result
of this stay, I published in first quartile journals, Phytomedicine or J. Ethnopharmacology, highlighting the
publication in Nature Biotechnology (first in IF in this field, 39) of a conformational study, by means of pulse
NMR, of a protein that inhibits entry of the HIV virus. I rejoined the U. Sevilla where I currently carry out my
teaching and research work. The latter, initially, were directed to the study of reactivity changes in restricted
geometry systems (DNA; polypeptides;) taking advantage of the learning of my postdoctoral stay. As of 2003 and
after working at the New Center for Scientific Research of La Isla de la Cartuja (CICIC), my research continues
to focus on the interaction of biomolecules with systems of restricted geometry, but already with nanoparticles. As
a result of this, I directed a Doctoral Thesis during this period, giving rise to various publications in first quartile
journals where the interaction of DNA with gold nanoparticles, AuNPs, was analyzed in detail. Likewise, the
analysis of aluminum or gold nanoparticles with small ligands has been published in PCCP or J. Phys. Chem. C. I
have recently published both reviews and book chapters focused on the surface recognition of DNA by AuNPs.
Currently my research deals with the interactions of proteins and DNA with AuNPs, optimizing these from a
kinetic and thermodynamic point of view. On the other hand, the obtaining in 2011 and 2013 of two invention
patents in the field of bionanomedicine and a third in 2016 for the detection in urine by AuNPs of a protein such
as lysozyme, linked to leukemia, allows me to collaborate with staff of the Virgen Macarena Hospital in Seville
to continue studying the potential use of AuNPs as biopolymer biosensors. At the age of 51, more than 101
publications, including books, book chapters, articles and patents and more than 54 participations in congresses
certify my research work, being the PI responsible for the FQM 386 Group “Synthesis and Physicochemistry of
Nanoparticles”. I reached the category of full professor (Catedrático) at the physical chemistry department of the
University of Sevilla in 2023.
