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Fernando Docobo Perez

Profesor Titular de Universidad
fdocobo1@us.es
Área de conocimiento: Microbiología
Departamento: Microbiología
Grupo: RESISTENCIA A ANTIMICROBIANOS - CTS-210 (Universidad de Sevilla)
Centro mixto: Instituto de Biomedicina de Sevilla (IBIS)

Investiga en

Tipo Año Título Fuente
Artículo2024 Evaluation of temocillin efficacy against KPC-2-producing Klebsiella pneumoniae isolates in a hollow-fibre infection model. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2024 Fosfomycin in bacteraemic urinary tract infection due to multidrug-resistant Escherichia coli: insights of post hoc DOOR analysis of the FOREST trial INFECTIOUS DISEASES
Artículo2024 Heterogeneity of SOS response expression in clinical isolates of Escherichia coli influences adaptation to antimicrobial stress DRUG RESISTANCE UPDATES
Artículo2024 Impact of suppression of the SOS response on protein expression in clinical isolates of Escherichia coli under antimicrobial pressure of ciprofloxacin FRONTIERS IN MICROBIOLOGY
Artículo2024 Implications of two-component systems EnvZ/OmpR and BaeS/BaeR in in vitro temocillin resistance in Escherichia coli. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2023 Effectiveness of fosfomycin trometamol as oral step-down therapy for bacteraemic urinary tract infections due to MDR Escherichia coli: a post hoc analysis of the FOREST randomized trial JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2023 Penicillin-binding protein occupancy dataset for 18 β-lactams and 4 β-lactamase inhibitors in neisseria gonorrhoeae MICROBIOLOGY SPECTRUM
Artículo2023 RecA inactivation as a strategy to reverse the heteroresistance phenomenon in clinical isolates of Escherichia coli. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2023 Recomendaciones del Comité Español del Antibiograma (COESANT) para la realización de los Informes de Sensibilidad Antibiótica Acumulada Enfermedades infecciosas y microbiología clínica
Revisión2023 Recommendations of the Spanish Antibiogram Committee (COESANT) for in vitro susceptibility testing of antimicrobial agents by disk diffusion Enfermedades infecciosas y microbiología clínica
Artículo2023 Synergistic effect of SOS response and GATC methylome suppression on antibiotic stress survival in Escherichia coli ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2022 Effect of Glycerol on Fosfomycin Activity against Escherichia coli Antibiotics
Artículo2022 Effect of RecA inactivation and detoxification systems on the evolution of ciprofloxacin resistance in Escherichia coli. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2022 Role of inorganic phosphate concentrations in in vitro activity of fosfomycin CLINICAL MICROBIOLOGY AND INFECTION
Artículo2022 Spanish Antibiogram Committee (COESANT) recommendations for cumulative antibiogram reports. Enfermedades infecciosas y microbiología clínica
Artículo2021 Activity of fosfomycin and amikacin against fosfomycin-heteroresistant Escherichia coli strains in a hollow-fiber infection model ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2021 Amikacin combined with fosfomycin for treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2021 Disbalancing Envelope Stress Responses as a Strategy for Sensitization of Escherichia coli to Antimicrobial Agents FRONTIERS IN MICROBIOLOGY
Artículo2021 Effect of RecA inactivation on quinolone susceptibility and the evolution of resistance in clinical isolates of Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2021 Interplay among different fosfomycin resistance mechanisms in klebsiella pneumoniae ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2021 Population Pharmacokinetics of Piperacillin in Non-Critically Ill Patients with Bacteremia Caused by Enterobacteriaceae. Antibiotics
Artículo2021 Synergistic quinolone sensitization by targeting the recA SOS response gene and oxidative stress ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2020 Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Nota2020 Detection of low-level fosfomycin-resistant variants by decreasing glucose-6-phosphate concentration in fosfomycin susceptibility determination Antibiotics
Artículo2020 Role of low-level quinolone resistance in generating tolerance in Escherichia coli under therapeutic concentrations of ciprofloxacin JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2019 Suppression of the SOS response modifies spatiotemporal evolution, post-antibiotic effect, bacterial fitness and biofilm formation in quinolone-resistant Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2018 Population pharmacokinetics and pharmacodynamics of fosfomycin in non-critically ill patients with bacteremic urinary infection caused by multidrug-resistant Escherichia coli CLINICAL MICROBIOLOGY AND INFECTION
Artículo2018 Urinary Tract Conditions Affect Fosfomycin Activity against Escherichia coli Strains Harboring Chromosomal Mutations Involved in Fosfomycin Uptake ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2017 Molecular insights into fosfomycin resistance in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2017 Quinolone Resistance Reversion by Targeting the SOS Response MBIO
Artículo2017 Role of inoculum and mutant frequency on fosfomycin MIC discrepancies by agar dilution and broth microdilution methods in Enterobacteriaceae CLINICAL MICROBIOLOGY AND INFECTION
Artículo2016 Impact of AAC(6 ')-Ib-cr in combination with chromosomal-mediated mechanisms on clinical quinolone resistance in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2016 Pharmacodynamics of vancomycin for CoNS infection: experimental basis for optimal use of vancomycin in neonates JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2016 Pharmacodynamics of Voriconazole in Children: Further Steps along the Path to True Individualized Therapy ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2015 Pharmacodynamics of Fosfomycin: Insights into Clinical Use for Antimicrobial Resistance ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Letter2014 Emergence of OXA-72-producing Acinetobacter pittii clinical isolates INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2014 Interplay between plasmid-mediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2014 Population Pharmacokinetics of Teicoplanin in Children ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2013 Impact of qnrA1, qnrB1 and qnrS1 on the efficacy of ciprofloxacin and levofloxacin in an experimental pneumonia model caused by Escherichia coli with or without the GyrA mutation Ser83Leu JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2013 Inoculum Effect on the Efficacies of Amoxicillin-Clavulanate, Piperacillin-Tazobactam, and Imipenem against Extended-Spectrum beta-Lactamase (ESBL)-Producing and Non-ESBL-Producing Escherichia coli in an Experimental Murine Sepsis Model ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Resumen congreso2013 PHARMACOKINETICS OF COLISTIN AFTER THE ADMINISTRATION OF A LOADING DOSE OF 4.5 MU OF COLISTIN METHANESULFONATE (CMS) IN OBESE CRITICALLY ILL PATIENTS VERSUS REGULAR WEIGHT CRITICALLY ILL PATIENTS INTENSIVE CARE MEDICINE
Artículo2012 Efficacies of colistin and tigecycline in mice with experimental pneumonia due to NDM-1-producing strains of Klebsiella pneumoniae and Escherichia coli INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2012 Efficacy of Daptomycin versus Vancomycin in an Experimental Model of Foreign-Body and Systemic Infection Caused by Biofilm Producers and Methicillin-Resistant Staphylococcus epidermidis ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2012 Efficacy of linezolid versus a pharmacodynamically optimized vancomycin therapy in an experimental pneumonia model caused by methicillin-resistant Staphylococcus aureus JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2012 In vitro and in vivo reduced fitness and virulence in ciprofloxacin-resistant Acinetobacter baumannii CLINICAL MICROBIOLOGY AND INFECTION
Artículo2012 Platelet-activating Factor Receptor Initiates Contact of Acinetobacter baumannii Expressing Phosphorylcholine with Host Cells JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2011 Acinetobacter baumannii-induced lung cell death: Role of inflammation, oxidative stress and cytosolic calcium MICROBIAL PATHOGENESIS
Letter2011 Attenuated virulence of a slow-growing pandrug-resistant Acinetobacter baumannii is associated with decreased expression of genes encoding the porins CarO and OprD-like INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2011 Efficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Artículo2011 Efficacy of rifampin, in monotherapy and in combinations, in an experimental murine pneumonia model caused by panresistant Acinetobacter baumannii strains EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Artículo2011 Impaired Virulence and In Vivo Fitness of Colistin-Resistant Acinetobacter baumannii JOURNAL OF INFECTIOUS DISEASES
Editorial2011 Local imipenem activity against Pseudomonas aeruginosa decreases in vivo in the presence of siliconized latex EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Artículo2011 Pre-clinical studies of a new quinolone (UB-8902) against Acinetobacter baumannii resistant to ciprofloxacin INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Resumen congreso2011 Preparation and design of a collaborative project for the proposal of the European Commission 7th Framework Programme 2010: Magicbullet project, a multidisciplinary experience BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2011 Vaccination with Outer Membrane Complexes Elicits Rapid Protective Immunity to Multidrug-Resistant Acinetobacter baumannii INFECTION AND IMMUNITY
Artículo2010 Comparative assessment of inoculum effects on the antimicrobial activity of amoxycillin-clavulanate and piperacillin-tazobactam with extended-spectrum beta-lactamase-producing and extended-spectrum beta-lactamase-non-producing Escherichia coli isolates CLINICAL MICROBIOLOGY AND INFECTION
Ponencia2010 EFECTO DE QNRA, QNRB Y QNRS EN LA ACTIVIDAD IN VIVO DE FLUOROQUINOLONAS EN CEPAS DE ESCHERICHIA COLI CON MUTACIÓN EN GYRA Enfermedades infecciosas y microbiología clínica
Póster2010 EFFECT OF QNRA, QNRB AND QNRS ON THE IN VIVO ACTIVITY OF FLUOROQUINOLONES CLINICAL MICROBIOLOGY AND INFECTION
Artículo2010 Efficacy of Rifampin and Its Combinations with Imipenem, Sulbactam, and Colistin in Experimental Models of Infection Caused by Imipenem-Resistant Acinetobacter baumannii ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2010 Efficacy of tigecycline vs. imipenem in the treatment of experimental Acinetobacter baumannii murine pneumonia EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Artículo2009 In Vitro Activity and In Vivo Efficacy of Clavulanic Acid against Acinetobacter baumannii ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2008 Activity of ciprofloxacin and levofloxacin in experimental pneumonia caused by Klebsiella pneumoniae deficient in porins, expressing active efflux and producing QnrA1 CLINICAL MICROBIOLOGY AND INFECTION
Artículo2008 Clinical Relevance and Prevalence of Polymorphisms in CYP3A5 and MDR1 Genes That Encode Tacrolimus Biotransformation Enzymes in Liver Transplant Recipients TRANSPLANTATION PROCEEDINGS
Artículo2008 Efficacy of amoxycillin-clavulanate in an experimental model of murine pneumonia caused by AmpC-non-hyperproducing clinical isolates of Escherichia coli resistant to cefoxitin CLINICAL MICROBIOLOGY AND INFECTION
Artículo2008 Molecular epidemiology of HIV type 1 in newly diagnosed patients in southern Spain AIDS RESEARCH AND HUMAN RETROVIRUSES
Artículo2008 Molecular Screening of Bartonella Species in Rodents from South Western Spain VECTOR-BORNE AND ZOONOTIC DISEASES
Artículo2007 Genotypic diversity of imipenem resistant isolates of Acinetobacter baumannii in Spain JOURNAL OF INFECTION
Artículo2007 Prevencion de la infeccion quirurgica utilizando sutura reabsorbible antibacteriana (vicryl plus) en lugar de la sutura reabsorbible convencional en hernioplastias. estudio experimental en animales. Cirugía española
Ponencia2006 ACTIVIDAD DE IMIPENEM EN LA PERITONITIS EXPERIMENTAL POR CUERPO EXTRAÑO (LÁTEX SILICONIZADO VS. SILICONA) CAUSADA POR PSEUDOMONAS AERUGINOSA. Enfermedades infecciosas y microbiología clínica
Artículo2006 Prevention of rifampicin resistance in Acinetobacter baumannii in an experimental pneumonia murine model, using rifampicin associated with imipenem or sulbactam JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Resumen congreso2006 Rifampin induction of resistance in Acinetobacter baumannii, in vitro and in an experimental pneumonia murine model CLINICAL MICROBIOLOGY AND INFECTION
Artículo2006 Studies on the antimicrobial activity of cecropin A-melittin hybrid peptides in colistin-resistant clinical isolates of Acinetobacter baumannii JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2005 Efficacy of beta-lactams against experimental pneumococcal endocarditis caused by strains with different susceptibilities to penicillin JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
05/10/2021 31/03/2023 Investigador/a Caracterización y optimización de la actividad de temocilina frente a enterobacterias resistentes a cefalosporinas de tercera generación (P20_00985) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
El investigador no tiene ningún resultado de investigación asociado