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Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial

Olivotto, Iacopo ; Oreziak, Artur; Barriales-Villa, Roberto; Abraham, Theodore P.; Masri, Ahmad; Garcia-Pavia, Pablo; Saberi, Sara; Lakdawala, Neal K.; Wheeler, Matthew T.; Owens, Anjali; Kubanek, Milos; Wojakowski, Wojciech; Jensen, Morten K.; Gimeno-Blanes, Juan; Afshar, Kia; Myers, Jonathan; Hegde, Sheila M.; Solomon, Scott D.; Sehnert, Amy J.; Zhang, David; Li, Wanying; Bhattacharya, Mondira; Edelberg, Jay M.; Waldman, Cynthia Burstein; Lester, Steven J.; Wang, Andrew; Ho, Carolyn Y.

Autoría grupal: Jacoby, Daniel (EXPLORER-HCM study investigators); Bartunek, Jozef (EXPLORER-HCM study investigators); Bondue, Antoine (EXPLORER-HCM study investigators); Van Craenenbroeck, Emeline (EXPLORER-HCM study investigators); Zemanek, David (EXPLORER-HCM study investigators); Jensen, Morten (EXPLORER-HCM study investigators); Mogensen, Jens (EXPLORER-HCM study investigators); Thune, Jens Jakob (EXPLORER-HCM study investigators); Charron, Philippe (EXPLORER-HCM study investigators); Hagege, Albert (EXPLORER-HCM study investigators); Lairez, Olivier (EXPLORER-HCM study investigators); Trochu, Jean Noël (EXPLORER-HCM study investigators); Axthelm, Christoph (EXPLORER-HCM study investigators); Duengen, Hans Dirk (EXPLORER-HCM study investigators); Frey, Norbert (EXPLORER-HCM study investigators); Mitrovic, Veselin (EXPLORER-HCM study investigators); Preusch, Michael (EXPLORER-HCM study investigators); Schulz-Menger, Jeanette (EXPLORER-HCM study investigators); Seidler, Tim (EXPLORER-HCM study investigators); Arad, Michael (EXPLORER-HCM study investigators); Halabi, Majdi (EXPLORER-HCM study investigators); Katz, Amos (EXPLORER-HCM study investigators); Monakier, Daniel (EXPLORER-HCM study investigators); Paz, Offir (EXPLORER-HCM study investigators); Viskin, Samuel (EXPLORER-HCM study investigators); Zwas, Donna (EXPLORER-HCM study investigators); Brunner-La Rocca, Hans Peter (EXPLORER-HCM study investigators); Michels, Michelle (EXPLORER-HCM study investigators); Dudek, Dariusz (EXPLORER-HCM study investigators); Oko-Sarnowska, Zofia (EXPLORER-HCM study investigators); Cardim, Nuno (EXPLORER-HCM study investigators); Pereira, Helder (EXPLORER-HCM study investigators); García Pavia, Pablo (EXPLORER-HCM study investigators); Hidalgo Urbano, Rafael (EXPLORER-HCM study investigators); Rincón Diaz, Luis Miguel (EXPLORER-HCM study investigators); Elliott, Perry (EXPLORER-HCM study investigators); Yousef, Zaheer (EXPLORER-HCM study investigators); Abraham, Theodore (EXPLORER-HCM study investigators); Alvarez, Paulino (EXPLORER-HCM study investigators); Bach, Richard (EXPLORER-HCM study investigators); Becker, Richard (EXPLORER-HCM study investigators); Choudhury, Lubna (EXPLORER-HCM study investigators); Fermin, David (EXPLORER-HCM study investigators); Jefferies, John (EXPLORER-HCM study investigators); Kramer, Christopher (EXPLORER-HCM study investigators); Lakdawala, Neal (EXPLORER-HCM study investigators); Lester, Steven (EXPLORER-HCM study investigators); Marian, Ali (EXPLORER-HCM study investigators); Maurer, Mathew (EXPLORER-HCM study investigators); Nagueh, Sherif (EXPLORER-HCM study investigators); Owens, David (EXPLORER-HCM study investigators); Rader, Florian (EXPLORER-HCM study investigators); Sherrid, Mark (EXPLORER-HCM study investigators); Shirani, Jamshid (EXPLORER-HCM study investigators); Symanski, John (EXPLORER-HCM study investigators); Turer, Aslan (EXPLORER-HCM study investigators); Wever-Pinzon, Omar (EXPLORER-HCM study investigators); Wheeler, Matthew (EXPLORER-HCM study investigators); Wong, Timothy (EXPLORER-HCM study investigators); Yamani, Mohamad (EXPLORER-HCM study investigators)

Tipo: Artículo
Año de Publicación: 2020
Volumen: 396
Número: 10253
Páginas: 759 - 769
Acceso abierto: Vía verde
Fuente Nº Citas Fecha Actualización
scopus61513-11-2024
wos53529-10-2024
Dimensions
PlumX
Altmetric

Año: 2020

Journal Impact Factor (JIF): 79.3230

CategoríaEdiciónPosiciónCuartilTercilDecil
MEDICINE, GENERAL & INTERNALSCIE2/167Q1T1D1

Año: 2020

Journal Citation Indicator (JCI): 20,050

CategoríaPosiciónCuartilTercilDecilPercentil
MEDICINE, GENERAL & INTERNAL2/315Q1T1D199,52

Año:

2020

CiteScore:

91,500

CategoríaPosiciónCuartilTercilDecil
Medicine (all)1/793Q1T1D1

SJR año:

2020

Factor de Impacto:

13,103

CategoríaPosiciónCuartilTercilDecil
Medicine (miscellaneous)6/2531Q1T1D1
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No exiten datos para esta publicación
# Autor Afiliación
1Olivotto, Iacopo Università degli Studi di Firenze; Azienda Ospedaliera Careggi (Italy)
2Oreziak, ArturInstytut Kardiologii im. Prymasa Tysiaclecia Stefana Kardynała Wyszynskiego (Poland)
3Barriales-Villa, RobertoUniversidade da Coruña; Centro de Investigación Biomédica en Red; Instituto de Investigación Biomédica de A Coruña; SERGAS (Servizo Galego de Saude) (Spain)
4Abraham, Theodore P.David Geffen School of Medicine at UCLA (United States)
5Masri, AhmadOHSU School of Medicine (United States)
6Garcia-Pavia, PabloHospital Universitario Puerta de Hierro; Universidad Francisco de Vitoria; Centro de Investigación Biomédica en Red (Spain)
7Saberi, SaraUniversity of Michigan, Ann Arbor (United States)
8Lakdawala, Neal K.Brigham and Women's Hospital (United States)
9Wheeler, Matthew T.Stanford University School of Medicine (United States)
10Owens, AnjaliUniversity of Pennsylvania Perelman School of Medicine (United States)
11Kubanek, MilosInstitutu Klinické a Experimentální Medicíny (Czech Republic)
12Wojakowski, WojciechSlaski Uniwersytet Medyczny w Katowicach (Poland)
13Jensen, Morten K.Aarhus Universitetshospital (Denmark)
14Gimeno-Blanes, JuanHospital Virgen de la Arrixaca (Spain)
15Afshar, KiaIntermountain Medical Center (United States)
16Myers, JonathanStanford University; VA Palo Alto Health Care System (United States)
17Hegde, Sheila M.Brigham and Women's Hospital (United States)
18Solomon, Scott D.Brigham and Women's Hospital (United States)
19Sehnert, Amy J.MyoKardia (United States)
20Zhang, DavidMyoKardia (United States)
21Li, WanyingMyoKardia (United States)
22Bhattacharya, MondiraMyoKardia (United States)
23Edelberg, Jay M.MyoKardia (United States)
24Waldman, Cynthia BursteinHCMBeat (United States)
25Lester, Steven J.Mayo Clinic Scottsdale-Phoenix, Arizona (United States)
26Wang, AndrewDuke University School of Medicine (United States)
27Ho, Carolyn Y.Brigham and Women's Hospital (United States)
# Autoría grupal Afiliación
1Jacoby, Daniel (EXPLORER-HCM study investigators)Yale University (United States)
2Bartunek, Jozef (EXPLORER-HCM study investigators)Sin datos ()
3Bondue, Antoine (EXPLORER-HCM study investigators)Sin datos ()
4Van Craenenbroeck, Emeline (EXPLORER-HCM study investigators)Sin datos ()
5Zemanek, David (EXPLORER-HCM study investigators)Sin datos ()
6Jensen, Morten (EXPLORER-HCM study investigators)Sin datos ()
7Mogensen, Jens (EXPLORER-HCM study investigators)Sin datos ()
8Thune, Jens Jakob (EXPLORER-HCM study investigators)Sin datos ()
9Charron, Philippe (EXPLORER-HCM study investigators)Sin datos ()
10Hagege, Albert (EXPLORER-HCM study investigators)Sin datos ()
11Lairez, Olivier (EXPLORER-HCM study investigators)Sin datos ()
12Trochu, Jean Noël (EXPLORER-HCM study investigators)Sin datos ()
13Axthelm, Christoph (EXPLORER-HCM study investigators)Sin datos ()
14Duengen, Hans Dirk (EXPLORER-HCM study investigators)Sin datos ()
15Frey, Norbert (EXPLORER-HCM study investigators)Sin datos ()
16Mitrovic, Veselin (EXPLORER-HCM study investigators)Sin datos ()
17Preusch, Michael (EXPLORER-HCM study investigators)Sin datos ()
18Schulz-Menger, Jeanette (EXPLORER-HCM study investigators)Sin datos ()
19Seidler, Tim (EXPLORER-HCM study investigators)Sin datos ()
20Arad, Michael (EXPLORER-HCM study investigators)Sin datos ()
21Halabi, Majdi (EXPLORER-HCM study investigators)Sin datos ()
22Katz, Amos (EXPLORER-HCM study investigators)Sin datos ()
23Monakier, Daniel (EXPLORER-HCM study investigators)Sin datos ()
24Paz, Offir (EXPLORER-HCM study investigators)Sin datos ()
25Viskin, Samuel (EXPLORER-HCM study investigators)Sin datos ()
26Zwas, Donna (EXPLORER-HCM study investigators)Sin datos ()
27Brunner-La Rocca, Hans Peter (EXPLORER-HCM study investigators)Sin datos ()
28Michels, Michelle (EXPLORER-HCM study investigators)Sin datos ()
29Dudek, Dariusz (EXPLORER-HCM study investigators)Sin datos ()
30Oko-Sarnowska, Zofia (EXPLORER-HCM study investigators)Sin datos ()
31Cardim, Nuno (EXPLORER-HCM study investigators)Sin datos ()
32Pereira, Helder (EXPLORER-HCM study investigators)Sin datos ()
33García Pavia, Pablo (EXPLORER-HCM study investigators)Sin datos ()
34Hidalgo Urbano, Rafael (EXPLORER-HCM study investigators)Sin datos ()
35Rincón Diaz, Luis Miguel (EXPLORER-HCM study investigators)Sin datos ()
36Elliott, Perry (EXPLORER-HCM study investigators)Sin datos ()
37Yousef, Zaheer (EXPLORER-HCM study investigators)Sin datos ()
38Abraham, Theodore (EXPLORER-HCM study investigators)Sin datos ()
39Alvarez, Paulino (EXPLORER-HCM study investigators)Sin datos ()
40Bach, Richard (EXPLORER-HCM study investigators)Sin datos ()
41Becker, Richard (EXPLORER-HCM study investigators)Sin datos ()
42Choudhury, Lubna (EXPLORER-HCM study investigators)Sin datos ()
43Fermin, David (EXPLORER-HCM study investigators)Sin datos ()
44Jefferies, John (EXPLORER-HCM study investigators)Sin datos ()
45Kramer, Christopher (EXPLORER-HCM study investigators)Sin datos ()
46Lakdawala, Neal (EXPLORER-HCM study investigators)Sin datos ()
47Lester, Steven (EXPLORER-HCM study investigators)Sin datos ()
48Marian, Ali (EXPLORER-HCM study investigators)Sin datos ()
49Maurer, Mathew (EXPLORER-HCM study investigators)Sin datos ()
50Nagueh, Sherif (EXPLORER-HCM study investigators)Sin datos ()
51Owens, David (EXPLORER-HCM study investigators)Sin datos ()
52Rader, Florian (EXPLORER-HCM study investigators)Sin datos ()
53Sherrid, Mark (EXPLORER-HCM study investigators)Sin datos ()
54Shirani, Jamshid (EXPLORER-HCM study investigators)Sin datos ()
55Symanski, John (EXPLORER-HCM study investigators)Sin datos ()
56Turer, Aslan (EXPLORER-HCM study investigators)Sin datos ()
57Wever-Pinzon, Omar (EXPLORER-HCM study investigators)Sin datos ()
58Wheeler, Matthew (EXPLORER-HCM study investigators)Sin datos ()
59Wong, Timothy (EXPLORER-HCM study investigators)Sin datos ()
60Yamani, Mohamad (EXPLORER-HCM study investigators)Sin datos ()