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Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

Green, AC; Marttila, P; Kiweler, N; Chalkiadaki, C; Wiita, E; Cookson, V; Lesur, A; Eiden, K; Bernardin, F; Vallin, KSA; Borhade, S; Long, M; Ghahe, EK; Jimenez-Alonso, JJ; Jemth, AS; Loseva, O; Mortusewicz, O; Meyers, M; Viry, E; Johansson, AI; Hodek, O; Homan, E; Bonagas, N; Ramos, L; Sandberg, L; Frodin, M; Moussay, E; Slipicevic, A; Letellier, E; Paggetti, J; Sorensen, CS; Helleday, T ; Henriksson, M ; Meiser, J 

Tipo: Artículo
Año de Publicación: 2023
Volumen: 5
Número: 4
Páginas: 642 - +
Acceso abierto: Vía híbrida
Fuente Nº Citas Fecha Actualización
scopus806-05-2024
wos806-05-2024
Dimensions
PlumX
Altmetric

Año: 2022

Journal Impact Factor (JIF): 20,8

CategoríaEdiciónPosiciónCuartilTercilDecil
ENDOCRINOLOGY & METABOLISMSCIE4/145Q1T1D1

Año: 2022

Journal Citation Indicator (JCI): 4,190

CategoríaPosiciónCuartilTercilDecilPercentil
ENDOCRINOLOGY & METABOLISM4/184Q1T1D198,10

Año:

2022

CiteScore:

23,800

CategoríaPosiciónCuartilTercilDecil
Cell Biology15/274Q1T1D1
Endocrinology, Diabetes and Metabolism5/232Q1T1D1
Internal Medicine4/140Q1T1D1
Physiology (medical)3/102Q1T1D1

SJR año:

2023

Factor de Impacto:

7,192

CategoríaPosiciónCuartilTercilDecil
Cell Biology12/295Q1T1D1
Endocrinology, Diabetes and Metabolism4/243Q1T1D1
Internal Medicine2/161Q1T1D1
Physiology (medical)3/112Q1T1D1
No existen datos para la revista de esta publicación.
Agencia Código de Proyecto
Cancer Metabolism Group at the Luxembourg Institute of Health-
DFG fellowshipKI 2508/1-1
FNR-ATTRACT programmeA18/BM/11809970
FNR-COREC21/BM/15718879
FNR-PRIDE i2TronPRIDE19/14254520
FNRS-Televie7.4509.20; 7.4572.22
Fondation CancerC20/BM/14582635; C20/BM/14592342
Helleday Foundation-
Karolinska Institute's KID-
Luxembourg National Research Fund (FNR)-
Mobility programme for the FPU predoctoral fellowship from Ministerio de Universidades of the Spanish GovernmentFPU17/02185
Novo Nordisk Foundation17OC0029972
Swedish Cancer Society2018/600; 2021/1490
Swedish Children's Cancer Foundation2021-0030; 2018-0095
Swedish Research Council2015-00162; 2017-06095; 2017-06095
University of Sheffield-
Vinnova2018-00257; 2021-04817; 2018-00257
Weston Park Cancer Centre-
Nota: los datos sobre financiación provienen de la WOS
# Autor Afiliación
1Green, ACUniversity of Sheffield; The University of Sheffield Medical School (England)
2Marttila, PKarolinska Institute Department of Oncology-Pathology (Sweden)
3Kiweler, NLuxembourg Institute of Health (Luxembourg)
4Chalkiadaki, CKarolinska Institute Department of Oncology-Pathology (Sweden)
5Wiita, EKarolinska Institute Department of Oncology-Pathology (Sweden)
6Cookson, VUniversity of Sheffield; The University of Sheffield Medical School (England)
7Lesur, ALuxembourg Institute of Health (Luxembourg)
8Eiden, KLuxembourg Institute of Health (Luxembourg)
9Bernardin, FLuxembourg Institute of Health (Luxembourg)
10Vallin, KSAKarolinska Institute Department of Oncology-Pathology; RISE Research Institutes of Sweden (Sweden)
11Borhade, SKarolinska Institute Department of Oncology-Pathology; RedGlead Discover (Sweden)
12Long, MKarolinska Institute Department of Oncology-Pathology (Sweden)
13Ghahe, EKUniversity of Copenhagen Biotech Research & Innovation Centre (Denmark)
14Jimenez-Alonso, JJUniversity of Seville Faculty of Pharmacy; Karolinska Institute Department of Oncology-Pathology (Sweden)
15Jemth, ASKarolinska Institute Department of Oncology-Pathology (Sweden)
16Loseva, OKarolinska Institute Department of Oncology-Pathology (Sweden)
17Mortusewicz, OKarolinska Institute Department of Oncology-Pathology (Sweden)
18Meyers, MUniversity of Luxembourg Faculty of Science Technology and Medicine (Luxembourg)
19Viry, ELuxembourg Institute of Health (Luxembourg)
20Johansson, AIUmea University (Sweden)
21Hodek, OSwedish University of Agricultural Sciences (Sweden)
22Homan, EKarolinska Institute Department of Oncology-Pathology (Sweden)
23Bonagas, NKarolinska Institute Department of Oncology-Pathology (Sweden)
24Ramos, LUniversity of Sheffield; The University of Sheffield Medical School (England)
25Sandberg, LStockholm University (Sweden)
26Frodin, MUniversity of Copenhagen Biotech Research & Innovation Centre (Denmark)
27Moussay, ELuxembourg Institute of Health (Luxembourg)
28Slipicevic, AKarolinska Institute Department of Oncology-Pathology; One Carbon Therapeut AB (Sweden)
29Letellier, EUniversity of Luxembourg Faculty of Science Technology and Medicine (Luxembourg)
30Paggetti, JLuxembourg Institute of Health (Luxembourg)
31Sorensen, CSUniversity of Copenhagen Biotech Research & Innovation Centre (Denmark)
32Helleday, T University of Sheffield; Karolinska Institute Department of Oncology-Pathology; The University of Sheffield Medical School (Sweden)
33Henriksson, M Karolinska Institute Department of Oncology-Pathology (Sweden)
34Meiser, J Luxembourg Institute of Health (Luxembourg)