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Publicaciones en la fuente INTERNATIONAL JOURNAL OF PHARMACEUTICS

Tipo Año Título Fuente
Artículo20243D-printed implants loaded with acriflavine for glioblastoma treatmentINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2024Amorphous solid dispersion of a binary formulation with felodipine and HPMC for 3D printed floating tablets.INTERNATIONAL JOURNAL OF PHARMACEUTICS
Corrección2024Corrigendum to “Aloe vera and copaiba oleoresin-loaded chitosan films for wound dressings: Microbial permeation, cytotoxicity, and in vivo proof of concept” [Int. J. Pharm. 634 (2023) 122648] (International Journal of Pharmaceutics (2023) 634, (S0378517323000686), (10.1016/j.ijpharm.2023.122648))INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2024Current trends in 3D printed gastroretentive floating drug delivery systems: A comprehensive review.INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2024Enhancement of skin localization of β-carotene from red fruit (Pandanus conoideus Lam.) using solid dispersion-thermoresponsive gel delivered via polymeric solid microneedlesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2024Ophthalmic wild olive (acebuche) oil nanoemulsions exert oculoprotective effects against oxidative stress induced by arterial hypertensionINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2024Optimising 3D printed medications for rare diseases: In-line mass uniformity testing in direct powder extrusion 3D printing.INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2024Synergistic antifungal activity against Candida albicans between voriconazole and cyclosporine a loaded in polymeric nanoparticlesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2023Aloe vera and copaiba oleoresin-loaded chitosan films for wound dressings: microbial permeation, cytotoxicity, and in vivo proof of conceptINTERNATIONAL JOURNAL OF PHARMACEUTICS
Corrección2023Corrigendum to “Development of intranasal implantable devices for schizophrenia treatment” [Int. J. Pharm. 624 (2021) 122061] (International Journal of Pharmaceutics (2022) 624, (S0378517322006159), (10.1016/j.ijpharm.2022.122061))INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2023Development of 3D-printed subcutaneous implants using concentrated polymer/drug solutionsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2023Fabrication and characterisation of poly(sulfonated) and poly(sulfonic acid) dissolving microneedles for delivery of antibiotic and antifungal agentsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2023Liposome-loaded polymeric microneedles for enhanced skin deposition of rifampicin.INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2022Development of intranasal implantable devices for schizophrenia treatmentINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2022pH-temperature dual-sensitive nucleolipid-containing stealth liposomes anchored with PEGylated AuNPs for triggering delivery of doxorubicin.INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2022Potential use for chronic pain: Poly(Ethylene Glycol)-Poly(Lactic-Co-Glycolic Acid) nanoparticles enhance the effects of Cannabis-Based terpenes on calcium influx in TRPV1-Expressing cellsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo20213D printed estradiol-eluting urogynecological mesh implants: Influence of material and mesh geometry on their mechanical propertiesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2021Enhancing intradermal delivery of tofacitinib citrate: Comparison between powder-loaded hollow microneedle arrays and dissolving microneedle arraysINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2021Fused deposition modelling for the development of drug loaded cardiovascular prosthesisINTERNATIONAL JOURNAL OF PHARMACEUTICS
Revisión2021Hollow microneedles: A perspective in biomedical applicationsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2021Oral administration of tipranavir with long-chain triglyceride results in moderate intestinal lymph targeting but no efficient delivery to HIV-1 reservoir in mesenteric lymph nodesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2021Poly(caprolactone)-based subcutaneous implant for sustained delivery of levothyroxineINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2020Development and characterisation of novel poly (vinyl alcohol)/poly (vinyl pyrrolidone)-based hydrogel-forming microneedle arrays for enhanced and sustained transdermal delivery of methotrexateINTERNATIONAL JOURNAL OF PHARMACEUTICS
Revisión2020Soil bioremediation by cyclodextrins. A reviewINTERNATIONAL JOURNAL OF PHARMACEUTICS
Revisión2020Urogynecological surgical mesh implants: New trends in materials, manufacturing and therapeutic approachesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2018Loading studies of the anticancer drug camptothecin into dual stimuli-sensitive nanoparticles. Stability scrutinyINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2017Calcium alginate microspheres containing metformin hydrochloride niosomes and chitosomes aimed for oral therapy of type 2 diabetes mellitusINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2017Folic acid-decorated and PEGylated PLGA nanoparticles for improving the antitumour activity of 5-fluorouracilINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2015A new biodegradable polythiourethane as controlled release matrix polymerINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2015In vitro and in vivo evaluation of Delta(9)-tetrahidrocannabinol/PLGA nanoparticles for cancer chemotherapyINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2015In vivo absorption behaviour of theophylline from starch-methyl methacrylate matrix tablets in beagle dogsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2015Towards a rational basis for selection of excipients: Excipient Efficiency for controlled releaseINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2014In vitro release testing of matrices based on starch methyl methacrylate copolymers: Effect of tablet crushing force, dissolution medium pH and stirring rateINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2013Biocompatible gemcitabine-based nanomedicine engineered by Flow Focusing (R) for efficient antitumor activityINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2012Compaction properties, drug release kinetics and fronts movement studies of matrices combining mixtures of swellable and inert polymers. III: Effect of polymer substitution typeINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2011Release behaviour of clozapine matrix pellets based on percolation theoryINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2010Compaction properties, drug release kinetics and fronts movement studies from matrices combining mixtures of swellable and inert polymers. II. Effect of HPMC with different degrees of methoxy/hydroxypropyl substitutionINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2010New "drug-in cyclodextrin-in deformable liposomes" formulations to improve the therapeutic efficacy of local anaestheticsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2010Role of the electrokinetic properties on the stability of mebendazole suspensions for veterinary applicationsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2010Study of critical points of drugs with different solubilities in hydrophilic matricesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2010Study of the critical points of experimental HPMC-NaCMC hydrophilic matricesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2009Protein-loaded PLGA microparticles engineered by flow focusing: Physicochemical characterization and protein detection by reversed-phase HPLCINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2008Application of percolation theory in the study of an extended release Verapamil hydrochloride formulationINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2008Compaction properties, drug release kinetics and fronts movement studies from matrices combining mixtures of swellable and inert polymers: Effect of HPMC of different viscosity gradesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2008Surface tension and rheology of aqueous dispersed systems containing a new hydrophobically modified polymer and surfactantsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2008Synthesis of lidocaine-loaded PLGA microparticles by flow focusing - Effects on drug loading and release propertiesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2007Application of statistical experimental design to study the formulation variables influencing the coating process of lidocaine liposomesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2006A bilogarithmic method for the spectrophotometric evaluation of stability constants of 1 : 1 weak complexes from mole ratio dataINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2006Effect of drug particle size in ultrasound compacted tablets - Continuum percolation model approachINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2006Effect of preparation technique on the properties of liposomes encapsulating ketoprofen-cyclodextrin complexes aimed for transdermal deliveryINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2006Spectrophotometric evaluation of stability constants of 1 : 1 weak complexes from continuous variation dataINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2006Straightforward production of encoded microbeads by Flow Focusing: Potential applications for biomolecule detectionINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2006Study of the critical points of HPMC hydrophilic matrices for controlled drug deliveryINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2005Continuous variation data: 1 : 1 or 2 : 2 weak complexes?INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2005Effect of cholesterol and ethanol on dermal delivery from DPPC liposomesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2005Preparation and characterisation of liposomes encapsulating ketoprofen-cyclodextrin complexes for transdermal drug deliveryINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2005Xanthan and galactomannan (from M-scabrella) matrix tablets for oral controlled delivery of theophyllineINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2002Alginate/chitosan particulate systems for sodium diclofenac releaseINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2002Development of sustained release matrix tablets of didanosine containing methacrylic and ethylcellulose polymersINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2002Didanosine extended-release matrix tablets: optimization of formulation variables using statistical experimental designINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2002Preparation and characterization by morphological analysis of diclofenac/PEG 4000 granules obtained using three different techniquesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2002The influence of carbohydrate nature and drying methods on the compaction properties and pore structure of new methyl methacrylate copolymersINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2000Fronts movement as a useful tool for hydrophilic matrix release mechanism elucidationINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1999Complexation of ursodeoxycholic acid with beta-cyclodextrin-choline dichloride coprecipitateINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1999Dehydration and rehydration of a hydrate diclofenac salt at room temperatureINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1999Design of controlled release inert matrices of naltrexone hydrochloride based on percolation conceptsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1999Effect of the temperature on a hydrate diclofenac saltINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1999Formation of ion-pairs in aqueous solutions of diclofenac saltsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1998Fractal and reactive dimensions of some ursodeoxycholic acid saltsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1998In vitro evaluation of alginate beads of a diclofenac saltINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1998Influence of two different types of excipient on drug percolation thresholdINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1998Physical characteristics of inclusion compounds of 5-ASA in alpha and beta cyclodextrinsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1998Study of morphine hydrochloride percolation threshold in Eudragit (R) RS-PM matricesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1998Thermal analysis of the dehydrated form of a diclofenac saltINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Contribution to the study of new graft copolymer matrices for drug delivery systems. Technological studyINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Design and evaluation of a new central core matrix tabletINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Disintegrating efficiency of croscarmellose sodium in a direct compression formulationINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Drug release from a new family of graft copolymers of methyl methacrylate .1.INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Force-displacement parameters of maltodextrins after the addition of lubricantsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Investigation of the triamterene-ß-cyclodextrin system prepared by co-grindingINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Particle and powder properties of cyclodextrinsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Solid-state characterization and dissolution characteristics of gliclazide-beta-cyclodextrin inclusion complexesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Solubility prediction of caffeine in aqueous N,N-dimethylformamide mixtures using the Extended Hildebrand Solubility ApproachINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Study of a complexation process between naltrexone and Eudragit(R) L as an oral controlled release systemINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Study of post-compressional parameters in the friction properties of maltodextrinsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1997Study of the complexation behaviour of gliclazide with partially methylated beta-cyclodextrin in solution and solid stateINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Characterization of modified paracetamol by means of SEM and fractal analysisINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Constant compression-decompression stress rate profiles to obtain rate dependence of maltodextrins for direct compressionINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Degradation kinetics of alpha-tocopherol in hydrophilic gelsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Fractal and reactive dimension in inert matrix systemsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Fractal and reactive dimension of a diclofenac salt: Effect of the experimental conditionsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996In vitro evaluation of sustained-release matrix tablets prepared with new modified polymeric carbohydratesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996On the buffer index of a single weak monoprotic acid systemINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Preclinical study of a controlled release oral morphine system in ratsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Preliminary study of different omeprazole-gamma-CD co-grinded systemsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Study of percolation thresholds in ternary tabletsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Therapeutic efficacy of hydrophilic gels of alpha-tocopherol and tretinoin in skin ulcers induced by adriamycin hydrochlorideINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996Thermal investigation of crystallization of polyethylene glycols in solid dispersions containing oxazepamINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1996X-ray tablet and raw diffraction as a method to study compression parameters in a direct compression excipient, Compril(R)INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995A rheological study of semisolid preparations of eudragit(r)INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Characterization study of a diclofenac salt by means of sem and fractal analysisINTERNATIONAL JOURNAL OF PHARMACEUTICS
Nota1995Determination of beta-adrenoceptor blocking-agents in tablets using reversed-phase high-performance liquid-chromatographyINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Determination of percolation thresholds in matrix-type controlled-release systems - application of a resistance analysis techniqueINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Elaboration and thermal study of interactions between cinnarizine and gelucire(R) 53/10 physical mixtures and solid dispersionsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Hydrophobicity of beta-adrenoceptor blocking-agents - study of correlations between retention in reversed-phase hplc systems and octanol-water partition constantsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Influence of crystallization solvent and dissolution behavior for a diclofenac saltINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Influence of diluents and manufacturing method on the in-vitro dissolution of carteolol hydrochloride matrix tabletsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Influence of the preparation method of solid dispersions on their dissolution rate: Study of triamterene-d-mannitol systemINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Physical characterization of carteolol - eudragit(r) l-binding interactionINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Study of the dissolution characteristics of oxazepam via complexation with β-cyclodextrinINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1995Use of fractal dimensions in the study of excipients - application to the characterization of modified lactosesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994A study of shear and compression deformations on hydrophilic gels of alpha-tocopherolINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994A study of shear and compression deformations on hydrophilic gels of tretinoinINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994Analysis of the physical characterization and the tabletability of calcium phosphate-based materialsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994DESIGN AND TESTING IN-VITRO OF A BIOADHESIVE AND FLOATING DRUG-DELIVERY SYSTEM FOR ORAL APPLICATIONINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994Evaluation of an adequate method of estimating flowability according to powder characteristicsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994Protection by alpha-tocopherol against skin ulcers induced by ionizing-radiationsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994Solubility of theophylline in aqueous n,n-dimethylformamide mixturesINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994Stability of hydrophilic gels of tretinoinINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994Study of the release mechanism of carteolol inert matrix tablets on the basis of percolation theoryINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1994Use of fractal geometry on the characterization of particles morphology - application to the diclofenac hydroxyethylpirrolidine saltINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Application of the extended hildebrand solubility parameter treatment for optimizing reversed-phase high-performance liquid-chromatography determination of pharmaceuticalsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993ASSESSMENT OF AN INVITRO METHOD FOR MEASURING THE BIOADHESIVENESS OF TABLETSINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Effects of different fillers and wetting liquids on the dissolution behavior of carteolol hydrochloride controlled-release inert matrix tabletsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Evaluation of acidity constants of dibasic acids and diacid bases from liquid-liquid distribution measurementsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Optimization of pharmaceutical formulations based on response-surface experimental-designsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Percolation theory - application to the study of the release behavior from inert matrix systemsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Practical digest for the evaluation of acidity constants of drugs by reversed-phase high performance liquid chromatographyINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Rheology and compression characteristics of lactose based direct compression excipientsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1993Study of thimerosal degradation mechanismINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1992An hyperbolic cosine method for the spectrophotometric evaluation of acidity constants of two-step overlapping equilibriaINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1992Buffer index in the titration of a monoprotic acid with a strong baseINTERNATIONAL JOURNAL OF PHARMACEUTICS
Nota1992Evaluation of ionization-constants of drugs in aqueous organic mixtures from reversed phase high-performance liquid-chromatographyINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1991Dissolution rate of diazepam from polyethylene-glycol 6000 solid dispersionsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Nota1991Drug solubility prediction by using solvatochromic parametersINTERNATIONAL JOURNAL OF PHARMACEUTICS
Nota1991Evaluation of acidity constants for sparingly soluble compounds from fluorescence measurementsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1991Spectrophotometric determination of acidity constants of compounds with unsuitable absorption featuresINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1989A bilogarithmic method for the evaluation of acidity constants of amphoteric substances from solubility measurementsINTERNATIONAL JOURNAL OF PHARMACEUTICS
Nota1988Evaluation of partition-coefficient and acidity constants of amphoteric substances by graphic differentiation of the distribution ratio against ph curveINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1987Spectrophotometric determination of cobalt in multivitaminic preparations with dipyridylglyoxal mono(2-pyridyl)hydrazoneINTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo1986Spectrophotometric evaluation of acidity constants of isonicotinic-acidINTERNATIONAL JOURNAL OF PHARMACEUTICS