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POLYMER NANOPARTICLE AGGREGATE, METHOD FOR PRODUCING SAME AND USE THEREOF FOR THE TREATMENT OF VENOUS THROMBOSIS

Tipo: Patente
Solicitantes:
Universidad de Sevilla (50%)
Servicio Andaluz de Salud (50%)
Solicitud
PCT/ES2024/070660
25-10-2024
Familia
WO2025088242A1; ES3015077A1
A first aspect of the present invention relates to a nanoparticle aggregate for the treatment of venous thrombosis characterised in that it comprises a combination of negatively charged nanoparticles comprising rtPA and positively charged nanoparticles comprising DNase per nanoparticle. A second aspect of the present invention relates to a method for producing the nanoparticle aggregate. A third aspect of the invention relates to a pharmaceutical composition comprising the nanoparticle aggregate according to the first aspect of the invention. Lastly, the present invention discloses the nanoparticle aggregate for use as a drug and for the treatment of thromboembolic diseases.
Materia: Necesidades corrientes de la vida / Técnicas industriales Diversas; Transportes
CIP: A61K38/46 (2025.05); A61K47/32 (2025.05); A61K9/52 (2025.05); A61P7/02 (2025.05); B82Y5/00 (2025.05)