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EPICRO - Prisma - Unidad de Bibliometría

EPIGENÉTICA Y CROMATINA EN EUCARIOTAS - BIO-321 (EPICRO)

Tipo de colectivo: Grupo de investigación
Estado: Grupo definitivo
Ámbito: Andalucía
Instituciones: Consejo Superior de Investigaciones Científicas. Centro Andaluz de Biología Molecular y Medicina Regenerativa (CSIC)
Fecha de creación: 17/10/2007

Investiga en

Palabras clave
Líneas de investigación
Resumen
Nombre Rol
González Arzola, Katiuska Miembro
Gonzalez Prieto, Roman Miembro
Tipo Año Título Fuente
Published Erratum2024 Author Correction: dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe. NATURE COMMUNICATIONS
Artículo2024 BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis NATURE COMMUNICATIONS
Corrección2024 dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe (vol 15, 5251 , 2024) NATURE COMMUNICATIONS
Artículo2024 dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe. NATURE COMMUNICATIONS
Artículo2024 Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability. PLOS GENETICS
Artículo2024 RNF212B E3 ligase is essential for crossover designation and maturation during male and female meiosis in the mouse PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2024 Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy NATURE COMMUNICATIONS
Revisión2024 The nucleolus: Coordinating stress response and genomic stability BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Artículo2024 UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168 NATURE COMMUNICATIONS
Artículo2023 A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Corrección2023 Author correction: Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells. NATURE COMMUNICATIONS
Artículo2023 CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2023 Mitochondrial Factors in the Cell Nucleus. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2023 SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome SCIENCE ADVANCES
Artículo2023 The lncRNA LETS1 promotes TGF-beta-induced EMT and cancer cell migration by transcriptionally activating a TbetaR1-stabilizing mechanism. SCIENCE SIGNALING
Artículo2023 Ubiquitinome profiling reveals inVivo UBE2D3 targets and implicates UBE2D3 in protein quality control. MOLECULAR & CELLULAR PROTEOMICS
Artículo2022 Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells. NATURE COMMUNICATIONS
Artículo2022 Insights in Post-Translational Modifications: Ubiquitin and SUMO INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Resumen congreso2022 NPM1 phase transition modulation via post-translational modifications and heterotypic interactions FEBS OPEN BIO
Artículo2022 Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation. NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo2022 PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ Computational and Structural Biotechnology Journal
Artículo2022 Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model GUT
Artículo2022 THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1 NUCLEIC ACIDS RESEARCH
Artículo2022 XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair NATURE COMMUNICATIONS
Artículo2021 A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair NATURE COMMUNICATIONS
Artículo2021 A proteomics study identifying interactors of the FSHD2 gene product SMCHD1 reveals RUVBL1-dependent DUX4 repression Scientific reports
Artículo2021 ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation NATURE CELL BIOLOGY
Artículo2021 ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients JOURNAL OF EXPERIMENTAL MEDICINE
Artículo2021 Global non-covalent SUMO interaction networks reveal SUMO-dependent stabilization of the non-homologous end joining complex CELL REPORTS
Capítulo2021 In Vivo Binding of Recombination Proteins to Non-DSB DNA Lesions and to Replication Forks Homologous recombination: methods and protocols
Artículo2021 Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome C REDOX BIOLOGY
Artículo2021 Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus. FEBS OPEN BIO
Resumen congreso2021 Molecular basis for the DNA damage-induced interaction between cytochrome c and the histone chaperone SET/TAF-I beta FEBS OPEN BIO
Artículo2021 Non-recombinogenic roles for Rad52 in translesion synthesis during DNA damage tolerance EMBO REPORTS
Artículo2021 Physical interactions between MCM and Rad51 facilitate replication fork lesion bypass and ssDNA gap filling by non-recombinogenic functions CELL REPORTS
Artículo2021 Proposed mechanism for regulation of H2O2-induced programmed cell death in plants by binding of cytochrome c to 14-3-3 proteins PLANT JOURNAL
Artículo2021 Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Artículo2021 Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining NATURE COMMUNICATIONS
Artículo2020 Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGF beta-Induced Breast Cancer Metastasis CLINICAL CANCER RESEARCH
Artículo2020 Exploring protein phosphorylation by combining computational approaches and biochemical methods Computational and Structural Biotechnology Journal
Artículo2020 The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II NATURE COMMUNICATIONS
Corrección2020 The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II (vol 11, 2104, 2020) NATURE COMMUNICATIONS
Resumen congreso2019 DNA damage triggers the interaction of cytochrome c with the disordered region of ANP32B FEBS OPEN BIO
Artículo2019 Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies JOURNAL OF BIOLOGICAL CHEMISTRY
Resumen congreso2019 Molecular basis for acute hypoxia-related diseases: Understanding the cross-talk between cytochrome c and hypoxia-induced protein HIGD1A in the mitochondria FEBS OPEN BIO
Revisión2019 New moonlighting functions of mitochondrial cytochrome c in the cytoplasm and nucleus FEBS LETTERS
Capítulo2019 TULIP: Targets of Ubiquitin Ligases Identified by Proteomics SUMOylation and Ubiquitination: Current and Emerging Concepts
Artículo2019 TULIP2: An Improved Method for the Identification of Ubiquitin E3-Specific Targets FRONTIERS IN CHEMISTRY
Artículo2019 USP7: combining tools towards selectivity CHEMICAL COMMUNICATIONS
Resumen congreso2018 Cytochrome c is revealed as a double activator of apoptosis through its interaction with 14-3-3 epsilon FEBS OPEN BIO
Artículo2018 Cytochrome c speeds up caspase cascade activation by blocking 14-3-3 epsilon-dependent Apaf-1 inhibition CELL DEATH & DISEASE
Artículo2018 Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Ponencia2017 Expanding the mitochondrial links to the DNA damage response FEBS JOURNAL
Artículo2017 Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c NUCLEIC ACIDS RESEARCH
Ponencia2017 Human SET/TAF-I beta and plant NRP1 are similarly inhibited by cytochrome c in the cell nucleus EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Ponencia2017 Phosphorylation of cytochrome c: Structure, dynamics and functions EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Ponencia2017 Post-translation tyrosine phosphorylation switches cytochrome c dynamics. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
Ponencia2017 Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Artículo2017 Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2017 The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery NATURE COMMUNICATIONS
Capítulo2016 Cytochrome c-Based Signalosome REDOX PROTEINS IN SUPERCOMPLEXES AND SIGNALOSOMES
Ponencia2015 A Common Cytochrome c-centred Signalosome for Programmed Cell Death in Humans and Plants FASEB JOURNAL
Ponencia2015 A Common Role for Cytochrome c in Programmed Cell Death in Humans and Plants PROTEIN SCIENCE
Ponencia2015 Additional binding sites for cytochrome c on its redox membrane partners facilitate its turnover and sliding mechanisms within respiratory supercomplexes PROTEIN SCIENCE
Artículo2015 c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4 CELL CYCLE
Ponencia2015 Phosphorylation of cytochrome c at positions 28 and 47 could affect its double role in the cell PROTEIN SCIENCE
Artículo2015 Respiratory complexes III and IV can each bind two molecules of cytochrome c at low ionic strength FEBS LETTERS
Artículo2015 Structural basis for inhibition of the histone chaperone activity of SET/TAF-I beta by cytochrome c PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2015 SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites EMBO REPORTS
Ponencia2014 A 'Floating Boat Bridge' of cytochrome c molecules in plant respirasome FEBS JOURNAL
Letter2014 A common signalosome for programmed cell death in humans and plants CELL DEATH & DISEASE
Resumen congreso2014 Cdc7, Rad53 and Asf1 stabilize Rad52 binding to replicative DNA damage FEBS JOURNAL
Artículo2014 Cytochrome c(1) exhibits two binding sites for cytochrome c in plants BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Ponencia2014 New role of cytochrome c in programmed cell death FEBS JOURNAL
Artículo2014 Structural and Functional Analysis of Novel Human Cytochrome c Targets in Apoptosis MOLECULAR & CELLULAR PROTEOMICS
Ponencia2013 Biointeractomics of cytochrome c under programmed cell death in plants and humans FEBS JOURNAL
Ponencia2013 How redox proteins form transient complexes in photosynthesis and respiration EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Artículo2013 New Arabidopsis thaliana Cytochrome c Partners: A Look Into the Elusive Role of Cytochrome c in Programmed Cell Death in Plants MOLECULAR & CELLULAR PROTEOMICS
Artículo2013 Rad51 replication fork recruitment is required for DNA damage tolerance EMBO JOURNAL
Revisión2013 Recent Methodological Advances in the Analysis of Protein Tyrosine Nitration CHEMPHYSCHEM
Artículo2012 Adsorption of a Laccase from Fusarium Proliferatum on Au(111) and HOPG Electrodes: a Scanning Probe Microscopy and Electrochemical Approach INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
Ponencia2012 Cytochrome c(1)-cytochrome c: an atypical transient complex FEBS JOURNAL
Ponencia2012 Cytochrome c(1): an old protein with novel functions FEBS JOURNAL
Artículo2011 Application of Flow Focusing to the Break-Up of a Magnetite Suspension Jet for the Production of Paramagnetic Microparticles JOURNAL OF NANOMATERIALS
Artículo2011 Histone H3K56 Acetylation, CAF1, and Rtt106 Coordinate Nucleosome Assembly and Stability of Advancing Replication Forks PLOS GENETICS
Artículo2010 Electrochemical and AFM characterization on gold and carbon electrodes of a high redox potential laccase from Fusarium proliferatum BIOELECTROCHEMISTRY
Artículo2009 Catalytic efficiency of natural and synthetic compounds used as laccase-mediators in oxidising veratryl alcohol and a kraft lignin, estimated by electrochemical analysis ELECTROCHIMICA ACTA
Artículo2007 Focusing capillary jets close to the continuum limit NATURE PHYSICS
Artículo2006 Early attack and subsequent changes produced in an industrial lignin by a fungal laccase and a laccase-mediator system: an analytical approach APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Artículo2006 Production, partial characterization and mass spectrometric studies of the extracellular laccase activity from Fusarium proliferatum APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Artículo2006 Straightforward production of encoded microbeads by Flow Focusing: Potential applications for biomolecule detection INTERNATIONAL JOURNAL OF PHARMACEUTICS

Proyectos de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/09/2024 15/11/2029 WOMEN AND MENOPAUSE: UNDERSTANDING HOW LIPIDS AND HORMONES ALTER THEIR CARDIOVASCULAR RISK” (2023 AXA CHAIR) AXA SA – AXA Research Fund (CERFA No. 11580*03) (Internacional) 1.000.000,00 €
01/09/2023 31/08/2025 Identificación de determinantes genéticos de la Sumoylación de Histonas (CNS2022-135216) Ministerio de Ciencia e Innovación (Nacional) 199.625,90 €
01/09/2022 31/08/2025 Consecuencias de la modificación del genoma con ubiquitina similares (PID2021-122361NA-I00) Ministerio de Ciencia e Innovación (Nacional) 163.350,00 €
01/01/2022 30/06/2025 Análisis Estructural y Funcional de la Red de Interacciones del Citocromo c en la Comunicación Mitocondria-Núcleo (PID2021-126663NB-I00) Ministerio de Ciencia e Innovación (Nacional) 242.000,00 €
01/09/2021 28/02/2025 Understanding how formation of stress granules can impact in plant stress resistance (PID2020-119737GA-I00) Ministerio de Ciencia e Innovación (Nacional) 108.900,00 €
12/05/2021 12/05/2024 Biointeractomica de la Reparacion del Daño en DNA en Condicines Homeostaticas y Patologicas DNA Damage (F. ARECES 21) Fundación Ramón Areces (Nacional) 112.000,00 €
01/02/2020 30/04/2022 Molecular Basis for Acute Hypoxia-Related Diseases: Understanding the Role of Cytochrome c in Respirasome Assembly and Functioning (US-1257019) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 80.000,00 €
01/01/2020 30/06/2023 Fuzzy Interactions between RNA Binding Proteins in Neurodegenerative Disorders (Fuzzy Disorders) (P18-FR-3487) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 125.500,00 €
01/01/2019 31/12/2021 Aproximaciones Estructurales y Funcionales a los Mecanismos Moleculares Dependientes de Citocromo C que Regulan la Actividad de las Chaperonas de Histonas Bajo Daño en el ADN (PGC2018-096049-B-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 190.575,00 €
01/01/2016 30/06/2019 Bases Estructurales de la Regulación Celular Mediada por Hur y Citocromo C (BFU2015-71017-P) Ministerio de Economía y Competitividad (Nacional) 213.444,00 €
07/04/2015 06/03/2017 Bases Moleculares de la Enfermedad: Biointeractómica de la Muerte Celular Programada (SUBPIVFRA/2015/015) Fundación Ramón Areces (Nacional) 117.200,00 €
01/01/2013 31/12/2015 Desvelando Nuevas Redes de Proteínas que Interaccionan con el Citocromo C: Análisis Comparativo Estructural y Funcional (BFU2012-31670) Ministerio de Economía y Competitividad (Nacional) 219.960,00 €
01/01/2010 31/12/2012 Bases estructurales, reconocimiento molecular y análisis evolutivo del citocromo C, una proteína bifuncional modificada post- tradiccionalmente (BFU2009-07190) Ministerio de Ciencia e Innovación (Nacional) 363.000,00 €
13/01/2009 31/12/2013 Búsqueda Estructural de Metaloproteínas Vegetales Capaces de Inhibir la Invasión Celular y Posterior Desarrollo del Parásito de la Malaria (P08-CVI-03876) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 259.923,68 €
31/01/2008 31/12/2012 Regulación Post-Transcripcional de la Muerte Celular Programada (P07-CVI-02896) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 170.000,00 €
01/10/2007 30/09/2010 Estudio y desarrollo de aplicaciones, métodos, física y diseño de dispositivos para la generación de chorros capilares y producción de partículas, aerosoles y espumas micro y nanométricos (DPI2007-63559) Ministerio de Educación y Ciencia (Nacional) 435.358,00 €
15/10/2004 14/10/2006 Novel Flow Focusing technology to produce microencapsulated probiotic bacteria for the food sector (FLOCAP) (COOP-CT-2004-513144) Commission of the European Communities (Research Directorate-General) (Europeo) 139.277,60 €

Contratos

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
27/10/2023 26/10/2026 Metabolómica de Enfermedades Neurodegenerativas con Acumulación Cerebral de Hierro mediante Resonancia Magnética Nuclear (ENACH Metabolomics) (4977/2038) ENACH Asociación (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/10/2015 30/09/2016 Taller FEBS sobre Biointeractómica: De las interacciones bimoleculares a las redes (BFU2015-63206-CIN) Ministerio de Economía y Competitividad (Nacional) 10.000,00 €
El colectivo no tiene ningún resultado de investigación asociado