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Miguel Fernandez Tenorio

María Zambrano (Investigador Distinguido)
mfernandez17@us.es
Área de conocimiento: Fisiología
Departamento: Fisiología Médica y Biofísica
Grupo: FISIOPATOLOGIA MOLECULAR DEL SISTEMA CARDIOVASCULAR - CTS-591 (Universidad de Sevilla)
Tipo Año Título Fuente
Artículo2024 Dual mode of action of IP3-dependent SR-Ca2+ release on local and global SR-Ca2+ release in ventricular cardiomyocytes JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Artículo2023 Detection and classification of Ca²⁺ release events in cardiomyocytes using 3D-UNet neural network BIOPHYSICAL JOURNAL
Resumen congreso2022 Ca2+ waves and the arrhythmogenicity paradigm: role of SERCA stimulation in a CPVT mouse model BIOPHYSICAL JOURNAL
Resumen congreso2022 Modulation of global Ca2+ handling by SR-Ca2+ release depending on IP3 BIOPHYSICAL JOURNAL
Artículo2022 Uptake-leak balance of SR Ca 2+ determines arrhythmogenic potential of Ry(R420Q+/- ) cardiomyocytes JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Artículo2021 Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation CIRCULATION RESEARCH
Artículo2020 Activation of endogenous protein phosphatase 1 enhances the calcium sensitivity of the ryanodine receptor type 2 in murine ventricular cardiomyocytes JOURNAL OF PHYSIOLOGY-LONDON
Resumen congreso2020 SERCA Stimulation Triggers Arrhythmogenic Ca2+ Events in Mouse Cardiomyocytes Harboring the RyR2(R42Q+/-) Mutation BIOPHYSICAL JOURNAL
Artículo2019 Automatic Detection and Classification of Ca2+ Release Events in Line- and Frame-Scan Images BIOPHYSICAL JOURNAL
Artículo2019 Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete beta-adrenergic response JOURNAL OF GENERAL PHYSIOLOGY
Capítulo2019 Simultaneous recording of subcellular Ca 2+ signals from the cytosol and sarco/endoplasmic reticulum: compartmentalized dye loading, imaging, and analysis Calcium-binding proteins of the EF-hand superfamily: from basics to medical applications
Resumen congreso2018 Dual Ablation of the RYR2-S2808 and RYR2-S2814 Sites Increases Propensity for Pro-arrhythmic Spontaneous Calcium Releases BIOPHYSICAL JOURNAL
Artículo2018 Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2 BIOCHEMISTRY
Artículo2018 Stabilization of Ca2+ signaling in cardiac muscle by stimulation of SERCA JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Resumen congreso2018 The RyR2(R420Q) Mutation Triggers Catecholaminergic Polymorphic Ventricular Tachycardia in Mouse Cardiomyocytes via SR Calcium Loading BIOPHYSICAL JOURNAL
Resumen congreso2017 Ablation of the RyR2-Ser2030 Phosphorylation Site Limits Changes in RyR2 Sensitivity during beta-Adrenergic Stimulation BIOPHYSICAL JOURNAL
Resumen congreso2017 Functional Effects of the RyR(2)(R420Q) Catecholaminergic Ventricular Polymorphic Tachycardia in Mouse Cardiomyocytes BIOPHYSICAL JOURNAL
Artículo2016 Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression. JACC: Basic to Translational Science
Resumen congreso2016 Protein Phosphatase-1 Increases Calcium Spark Frequency in Murine Cardiomyocytes via Modulation of RyR2 Phosphorylation BIOPHYSICAL JOURNAL
Artículo2016 Real-time intra-store confocal Ca2+ imaging in isolated mouse cardiomyocytes CELL CALCIUM
Corrección2015 Erratum: Oxidative Stress and Ca2D Release Events in Mouse Cardiomyocytes (Biophysical Journal (2014) 107 (2815-2827)) BIOPHYSICAL JOURNAL
Resumen congreso2015 Opposite Changes of Ca2+ Wave Threshold and Fractional SR Ca2+ Release during SERCA Stimulation in Cardiomyocytes BIOPHYSICAL JOURNAL
Resumen congreso2014 Extracting Detailed Ca2+ Signaling Information from Noisy Confocal Images BIOPHYSICAL JOURNAL
Artículo2014 Oxidative stress and Ca2+ release events in mouse cardiomyocytes BIOPHYSICAL JOURNAL
Resumen congreso2014 Serca Stimulation Increases Intra-Sr Ca(2+)Threshold for Ca2+ Waves in Cadiomyocytes BIOPHYSICAL JOURNAL
Revisión2013 A new metabotropic role for L-type Ca2+ channels in vascular smooth muscle contraction CURRENT VASCULAR PHARMACOLOGY
Resumen congreso2013 Direct CaMKII Activation by Endogenous Nitric Oxide Modulates Calcium Spark Frequency in Cardiomyocytes BIOPHYSICAL JOURNAL
Resumen congreso2013 Improved Protocol to Record Sarcoplasmic Reticulum Calcium Concentrations in Mouse Cardiomyocytes BIOPHYSICAL JOURNAL
Artículo2013 NO-dependent CaMKII activation during beta-adrenergic stimulation of cardiac muscle CARDIOVASCULAR RESEARCH
Artículo2012 Tonic arterial contraction mediated by L-type Ca2+ channels requires sustained Ca2+ influx, G protein-associated Ca2+ release, and RhoA/ROCK activation EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2011 Metabotropic Regulation of RhoA/Rho-Associated Kinase by L-type Ca2+ Channels New Mechanism for Depolarization-Evoked Mammalian Arterial Contraction CIRCULATION RESEARCH
Resumen congreso2011 Voltage-dependent regulation of intracellular calcium release in vascular smooth muscle JOURNAL OF VASCULAR RESEARCH
Artículo2010 Genetic Ablation of L-Type Ca2+ Channels Abolishes Depolarization-Induced Ca2+ Release in Arterial Smooth Muscle CIRCULATION RESEARCH
Artículo2009 Hypoxia inhibits vasoconstriction induced by metabotropic Ca2+ channel-induced Ca2+ release in mammalian coronary arteries CARDIOVASCULAR RESEARCH
Este investigador no ha dirigido/tutorizado tesis

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
02/12/2022 31/12/2025 Investigador/a AKAP9 como modificador genético en el Síndrome de QT largo Tipo 1 (PROYEXCEL_00597) Junta de Andalucía (Consejería de Transformación Económica, Industria, Conocimiento y Universidades) (Autonómico)
01/04/2009 31/03/2014 Investigador/a Nuevo Papel de los Canales de Ca2+ en el Control del Tono Vascular y su Relación con Mecanismos de Sensibilización a Ca2+ de la Contracción (P08-CTS-03530) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/04/2009 31/03/2014 Contratado Nuevo Papel de los Canales de Ca2+ en el Control del Tono Vascular y su Relación con Mecanismos de Sensibilización a Ca2+ de la Contracción (P08-CTS-03530) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/01/2007 31/12/2012 Investigador/a Sensibilidad al oxígeno y neurodegeneración (CONFMB-001/2006) Fundación Marcelino Botín (Nacional)
El investigador no tiene ningún resultado de investigación asociado