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Simón Méndez Ferrer

Atrae
smendez@us.es
Área de conocimiento: Fisiología
Departamento: Fisiología Médica y Biofísica
Grupo: Sin grupo
Centro mixto: Instituto de Biomedicina de Sevilla (IBIS)

Investiga en

Tipo Año Título Fuente
Artículo2025 Bone marrow mesenchymal stromal cells support translation in refractory acute myeloid leukemia CELL REPORTS
Nota2025 NO-immune privilege for hematopoietic stem cells CELL RESEARCH
Resumen congreso2024 A descriptive study on the prescription of monoclonal antibodies against the calcitonin generelated peptide pathway for refractory migraine in a tertiary hospital BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Resumen congreso2024 Analysis of new medicine approvals in the European Union: A 5-year review of the CHMP BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Resumen congreso2024 Descriptive study of drugs of abuse in psychiatric admissions to a tertiary hospital BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Resumen congreso2024 Detection of psychoactive substances in a tertiary hospital from 2019 to 2022: A descriptive study BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Resumen congreso2024 Extended use of N-acetylcysteine perfusion in acute acetaminophen intoxication: A case report BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2024 IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells Blood Advances
Resumen congreso2024 Serum valproic acid levels in patients with psychiatric disorders in a tertiary care hospital: A descriptive study BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2023 Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms NATURE CANCER
Artículo2023 Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis NATURE COMMUNICATIONS
Editorial2023 The Inflamed Niche : A Double-Edged Sword in AML? BLOOD CANCER DISCOVERY
Artículo2022 A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise. Cell Stem Cell
Artículo2022 Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis NATURE COMMUNICATIONS
Artículo2022 Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm NATURE COMMUNICATIONS
Artículo2022 Megakaryocyte Diversity in Ontogeny, Functions and Cell-Cell Interactions FRONTIERS IN ONCOLOGY
Artículo2022 Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta NATURE CELL BIOLOGY
Capítulo2022 Myeloproliferative Neoplasms Encyclopedia of Cell Biology: Volume 1-6, Second Edition
Editorial2022 RIG-Ing out BMSCs for hematopoietic recovery after transplantation BLOOD
Artículo2022 Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression JOURNAL OF CLINICAL INVESTIGATION
Editorial2022 Stem cells "aclymatise" to regenerate the blood system EMBO JOURNAL
Artículo2022 The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells LEUKEMIA
Editorial2022 The EHA Research Roadmap: Hematopoietic Stem Cells and Allotransplantation HemaSphere
Revisión2021 Cellular Heterogeneity of Mesenchymal Stem/Stromal Cells in the Bone Marrow FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Corrección2021 Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (vol 10, 1225, 2020) FRONTIERS IN ONCOLOGY
Capítulo2021 Haematopoietic Stem Cell Niches in the Bone Marrow Stem Cell Biology and Regenerative Medicine, Second Edition
Artículo2021 Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages CELL DEATH & DISEASE
Artículo2021 Multicolor Immunofluorescence Staining of Paraffin-Embedded Human Bone Marrow Sections BONE MARROW ENVIRONMENT
Artículo2021 Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1 NATURE COMMUNICATIONS
Editorial2021 The EHA Research Roadmap: Normal Hematopoiesis HemaSphere
Resumen congreso2020 Bitter taste receptors system is expressed and functional in both HSCs and leukemic cells CANCER RESEARCH
Artículo2020 Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy CELL METABOLISM
Revisión2020 Bone marrow niches in haematological malignancies Nature Reviews. Cancer
Artículo2020 Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells FRONTIERS IN ONCOLOGY
Resumen congreso2020 Effects of Tamoxifen on the Mutant Allele Burden and Disease Course in Patients with Myeloproliferative Neoplasms - Results of the Tamarin Study BLOOD
Editorial2020 HSCs revive their niche after transplantation BLOOD
Artículo2020 Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis ANNALS OF THE RHEUMATIC DISEASES
Revisión2020 Microenvironmental contributions to hematopoietic stem cell aging HAEMATOLOGICA
Revisión2020 Neuronal regulation of bone marrow stem cell niches F1000Research
Artículo2020 Sox17 Controls Emergence and Remodeling of Nestin-Expressing Coronary Vessels CIRCULATION RESEARCH
Artículo2020 The Autonomic Nervous System Pulls the Strings to Coordinate Circadian HSC Functions FRONTIERS IN IMMUNOLOGY
Resumen congreso2019 CHANGING NEIGHBOURS: BONE MARROW REMODELLING DURING AGING AND AGE-RELATED MYELOPROLIFERATIVE DISORDERS EXPERIMENTAL HEMATOLOGY
Artículo2019 Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes BLOOD
Artículo2019 Haematopoietic stem cells in perisinusoidal niches are protected from ageing NATURE CELL BIOLOGY
Editorial2019 Molecular interactome between HSCs and their niches BLOOD
Artículo2019 Remodeling of bone marrow hematopoietic stem cell niches promotes myeloid cell expansion during premature or physiological aging Cell Stem Cell
Artículo2019 The sympathomimetic agonist mirabegron did not lower JAK2-V617F allele burden, but restored nestin-positive cells and reduced reticulin fibrosis in patients with myeloproliferative neoplasms: results of phase II study SAKK 33/14 HAEMATOLOGICA
Revisión2019 Updates on the hematologic tumor microenvironment and its therapeutic targeting HAEMATOLOGICA
Artículo2019 Vascular Interstitial Cells in Retinal Arteriolar Annuli Are Altered During Hypertension INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Resumen congreso2018 Aging of bone marrow microenvironment promotes myeloid bias of hematopoietic progenitors and is a target in age-related myeloproliferative neoplasms BLOOD
Resumen congreso2018 Bitter Taste Receptors System Is Expressed and Functional in Both HSCs and Leukemic Cells BLOOD
Artículo2018 Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance Cell Stem Cell
Resumen congreso2018 Feasibility of recruitment of patients with Myeloproliferative Neoplasms into the TAP funded TAMARIN study BRITISH JOURNAL OF HAEMATOLOGY
Resumen congreso2018 HEMATOPOIETIC STEM CELLS IN PERISINUSOIDAL NICHES ARE PROTECTED FROM AGING EXPERIMENTAL HEMATOLOGY
Resumen congreso2018 Niche Heterogeneity Impacts Evolution of Myeloproliferative Neoplasms Driven By the Same Oncogenic Pathway BLOOD
Artículo2018 Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia NATURE COMMUNICATIONS
Editorial2018 The microenvironment in myeloproliferative neoplasm HemaSphere
Editorial2017 Dynamic T-ALL-niche cell interactions T-ALL: several homes rather than homeless? IMMUNOLOGY AND CELL BIOLOGY
Editorial2017 Human and mouse leukocytes: different clockwork BLOOD
Resumen congreso2017 Leukemic Stem Cells Co-Opt Normal Bone Marrow Niches As a Source of Energy and Antioxidant Defence BLOOD
Artículo2017 Myeloid malignancies and the microenvironment BLOOD
Artículo2017 Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate ONCOTARGET
Artículo2017 The evolving view of the hematopoietic stem cell niche EXPERIMENTAL HEMATOLOGY
Revisión2017 The hematopoietic stem-cell niche in health and leukemia CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2016 A Novel Systems-Biology Algorithm for the Analysis of Coordinated Protein Responses Using Quantitative Proteomics MOLECULAR & CELLULAR PROTEOMICS
Resumen congreso2016 Effects of the Sympathicomimetic Agonist Mirabegron on Disease Course, Mutant Allele Burden, Marrow Fibrosis, and Nestin Positive Stem Cell Niche in Patients with JAK2-Mutated Myeloproliferative Neoplasms. a Prospective Multicenter Phase II Trial SAKK 33/14 BLOOD
Resumen congreso2016 Leukemia development and the microenvironment CANCER RESEARCH
Resumen congreso2016 Mesensphere cultures but not adherent culture conditions conserve the stem cell properties of human primary bone marrow lin-/CD45-/CD271+/CD140a-stroma cells BONE MARROW TRANSPLANTATION
Artículo2016 Nestin(+) cells direct inflammatory cell migration in atherosclerosis NATURE COMMUNICATIONS
Artículo2016 Regulation of hematopoietic progenitors by estrogens as a basis for new antileukemic strategies MOLECULAR & CELLULAR ONCOLOGY
Artículo2016 The European Hematology Association Roadmap for European Hematology Research: a consensus document HAEMATOLOGICA
Editorial2016 Under Pressure: When a Transformed Environment Pushes Cells to Malignancy Cell Stem Cell
Artículo2015 BMSCs and hematopoiesis IMMUNOLOGY LETTERS
Revisión2015 Bone marrow stem cells: current and emerging concepts MARROW
Editorial2015 Convert and Conquer: The Strategy of Chronic Myelogenous Leukemic Cells CANCER CELL
Resumen congreso2015 Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells BLOOD
Resumen congreso2015 Noncellular Niche Influences: Nervous System Mediators, Metabolic Mediators, and Hypoxia/Oxidative Stress BLOOD
Resumen congreso2015 Spatiotemporal Regulation of Hematopoietic Stem Cell Niches By Dual Cholinergic Signaling BLOOD
Artículo2015 Traumatic brain injury caused by "balconing" BRITISH JOURNAL OF NEUROSURGERY
Resumen congreso2014 Are MSCs Stem Cells? Demonstration of in Vitro and in Vivo Stem Cell Properties of Highly Enriched linneg/CD45neg/CD271pos/CD140alow/Neg Mesenchymal Stromal Cells from Adult Human Bone Marrow BLOOD
Resumen congreso2014 DISTINCT MOLECULAR SIGNATURE AND POTENT HEMATOPOIESIS-SUPPORTING FUNCTION OF HIGHLY ENRICHED PRIMARY HUMAN BONE MARROW LINEAGE NEG/CD45 NEG/CD271 POS/PDGFR-ALPHA LOW/NEG STROMA STEM CELLS BONE MARROW TRANSPLANTATION
Artículo2014 Estrogen Signaling Selectively Induces Apoptosis of Hematopoietic Progenitors and Myeloid Neoplasms without Harming Steady-State Hematopoiesis Cell Stem Cell
Artículo2014 Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning BLOOD
Artículo2014 Low/Negative Expression of PDGFR-α Identifies the Candidate Primary Mesenchymal Stromal Cells in Adult Human Bone Marrow STEM CELL REPORTS
Artículo2014 Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms NATURE
Resumen congreso2014 NOVEL NEUROENDOCRINE REGULATION OF BONE MARROW STEM CELLS PROVIDES POTENTIAL COMBINED THERAPEUTIC TARGETING OF LEUKAEMIC STEM CELLS AND THEIR MICROENVIRONMENT EXPERIMENTAL HEMATOLOGY
Artículo2014 The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem-cell-niche function eLife
Editorial2013 Autonomic regulation of hematopoiesis and cancer HAEMATOLOGICA
Capítulo2013 Carotid body transplants as a therapy for Parkinson's disease EMERGING DRUGS AND TARGETS FOR PARKINSON'S DISEASE
Editorial2013 CELL BIOLOGY Tumour stem cells in bone NATURE
Resumen congreso2013 CIRCADIAN PARASYMPATHETIC REGULATION OF HEMATOPOIETIC STEM CELL TRAFFIC EXPERIMENTAL HEMATOLOGY
Editorial2013 Intracardiac Migration of a Ventriculoperitoneal Shunt Canadian Journal of Neurological Sciences
Editorial2013 Mitochondria underlie different metabolism of hematopoietic stem and progenitor cells HAEMATOLOGICA
Resumen congreso2013 Neural crest contributions to the haematopoietic stem-cell niche HUMAN GENE THERAPY
Editorial2013 Pathologic cervical fracture in a patient with secondary hyperparathyroidism KIDNEY INTERNATIONAL
Resumen congreso2013 Primary Linneg/CD45neg/CD271pos/PDGFRαlow/Neg Stroma Stem Cells In Adult Huan Bone Marrow Show a Distinct Molecular Signature and Potent Hematopoiesis-Supporting Function BLOOD
Resumen congreso2013 REGULATION OF NORMAL AND LEUKEMIC ADULT HEMATOPOIETIC STEM CELLS BY ESTROGEN SIGNALING HAEMATOLOGICA
Resumen congreso2013 Selective regulation of hematopoietic progenitors by estrogens as a basis for anti-leukemic strategies HUMAN GENE THERAPY
Artículo2013 Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion CELL REPORTS
Resumen congreso2013 Sympathetic Neuropathy Of The Hematopoietic Stem Cell Niche Is Essential For Myeloproliferative Neoplasms BLOOD
Artículo2013 Traumatic epidural retroclival hematoma with odontoid fracture and cardiorespiratory arrest SPINAL CORD
Artículo2013 Uncal decompression in gliomatosis cerebri Neurochirurgie
Resumen congreso2012 DIFFERENTIAL CONTRIBUTION OF EMBRYONIC MURINE BONE MARROW MESENCHYMAL PROGENITOR CELLS TO SKELETAL AND HEMATOPOIETIC DEVELOPMENT EXPERIMENTAL HEMATOLOGY
Artículo2012 Intercapillary bridging cells: Immunocytochemical characteristics of cells that connect blood vessels in the retina EXPERIMENTAL EYE RESEARCH
Artículo2012 Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields BLOOD
Artículo2011 Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche JOURNAL OF EXPERIMENTAL MEDICINE
Artículo2011 Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands IMMUNITY
Artículo2011 Diabetes impairs hematopoietic stem cell mobilization by altering niche function Science Translational Medicine
Artículo2011 Stem cell interactions in a bone marrow niche Current Osteoporosis Reports
Revisión2011 Stem cell self-renewal: Lessons from bone marrow, gut and iPS toward clinical applications LEUKEMIA
Ponencia2010 Cooperation of β2- and β3-adrenergic receptors in hematopoietic progenitor cell mobilization ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Artículo2010 Mesenchymal and haematopoietic stem cells form a unique bone marrow niche NATURE
Revisión2009 Circadian rhythms influence hematopoietic stem cells Current Opinion in Hematology
Artículo2009 Gαs Uncouples Hematopoietic Stem Cell Homing and Mobilization Cell Stem Cell
Artículo2008 Haematopoietic stem cell release is regulated by circadian oscillations NATURE
Artículo2007 Carotid body autotransplantation in Parkinson disease: a clinical and positron emission tomography study JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Ponencia2007 Hematopoietic stem cell trafficking: Regulated adhesion and attraction to bone marrow microenvironment ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Capítulo2006 Cardiac stem cells for myocardial regeneration Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair: From Basic Research to Clinical Applications
Artículo2006 Resident human cardiac stem cells: Role in cardiac cellular homeostasis and potential for myocardial regeneration Nature Clinical Practice Cardiovascular Medicine
Artículo2006 Resident progenitors and bone marrow stem cells in myocardial renewal and repair Nature Clinical Practice Cardiovascular Medicine
Artículo2005 Selective glial cell line-derived neurotrophic factor production in adult dopaminergic carotid body cells in situ and after intrastriatal transplantation JOURNAL OF NEUROSCIENCE
Artículo2003 Autotransplantation of human carotid body cell aggregates for treatment of Parkinson's disease Neurosurgery
Artículo2003 Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats JOURNAL OF NEUROSCIENCE
Artículo2002 Dopaminergic cells of the carotid body: Physiological significance and possible therapeutic applications in Parkinson's disease BRAIN RESEARCH BULLETIN
Artículo2001 Identification of a new water channel (Rg-MIP) in the Malpighian tubules of the insect Rhodnius prolixus PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Este investigador no ha dirigido/tutorizado tesis

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2022 31/05/2023 Investigador/a Caracterización del papel de las células nestina+ en el miocardio infartado. Implicación en inflamación y fibrosis (US-1381135) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
01/12/2024 30/11/2028 Investigador/a Integrated multi-angle research and training network to eradicate leukemia minimal residual disease (MIRACLE) (GA-101167512) European Commission (Europeo)
El investigador no tiene ningún resultado de investigación asociado