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Publicaciones en la fuente EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Tipo Año Título Fuente
Artículo2024Biological evaluation of carbohydrate-based aprepitant analogs for neuroblastoma treatmentEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2023Fluoro-labelled sp2-iminoglycolipids with immunomodulatory propertiesEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2023Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancerEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2022Enantioselective synthesis of 4-amino-3,4-dihydrocoumarins and their non-cyclic hydroxyester precursors: Biological evaluation for the treatment of glioblastoma multiformeEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2022Identification of new FK866 analogues with potent anticancer activity against pancreatic cancerEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2022Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agentsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Revisión20202-substituted benzothiazoles as antiproliferative agents: novel insights on structure-activity relationshipsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2020Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agentsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2020Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry diseaseEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2019New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phasesEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2019Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculationsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2019sp(2)-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivoEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2019Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapiesEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2019Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitorsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2018Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitorsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2018Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cellsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2018Synthesis of unprecedented steroidal Spiro heterocycles as potential antiproliferative drugsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modificationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017Molecular topology: A new strategy for antimicrobial resistance controlEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agentsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017Tuning of beta-glucosidase and alpha-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid moleculesEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2016Asp32 and Asp228 determine the selective inhibition of BACE1 as shown by docking and molecular dynamics simulationsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2016Efficient stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc) and sp(2)-iminosugar conjugates: Novel hexosaminidase inhibitors with discrimination capabilities between the mature and precursor forms of the enzymeEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2016Inhibitor versus chaperone behaviour of D-fagomine, DAB and LAB sp2-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblastsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2016Selenoureido-iminosugars: A new family of multitarget drugsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2016Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agentsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015Conformationally-locked N-glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher diseaseEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profileEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015Phenolic thio- and selenosemicarbazones as multi-target drugsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015Sequence-activity relationship, and mechanism of action of mastoparan analogues against extended-drug resistant Acinetobacter baumanniiEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2014Anti-proliferative activity of 2,6-dichloro-9-or 7-(ethoxycarbonylmethyl)-9H- or 7H-purines against several human solid tumour cell linesEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2014Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activityEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2013Aziridines from alkenyl-beta-D-galactopyranoside derivatives: Stereoselective synthesis and in vitro selective anticancer activityEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2012Isoprenyl-thiourea and urea derivatives as new farnesyl diphosphate analogues: Synthesis and in vitro antimicrobial and cytotoxic activitiesEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY