Artículo | 2025 |
β-Cyclodextrin-based geometrically frustrated amphiphiles as one-component, cell-specific and organ-specific nucleic acid delivery systems
|
CARBOHYDRATE POLYMERS |
Artículo | 2024 |
High-Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC-SIGN and Langerin
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2024 |
sp2-Iminosugar azobenzene O-glycosides: light-sensitive glycosidase inhibitors with unprecedented tunability and switching factors
|
BIOORGANIC CHEMISTRY |
Artículo | 2024 |
Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
|
ANALYTICAL CHEMISTRY |
Artículo | 2024 |
Trehalose-polyamine/DNA nanocomplexes: impact of vector architecture on cell and organ transfection selectivity.
|
JOURNAL OF MATERIALS CHEMISTRY B |
Artículo | 2023 |
Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2023 |
Potent and selective cell-active iminosugar inhibitors of human α-N-acetylgalactosaminidase (α-NAGAL)
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2023 |
Reversible light-induced dimerization of secondary face azobenzene-functionalized β-cyclodextrin derivatives
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2023 |
Serine-/Cysteine-based sp2-Iminoglycolipids as novel TLR4 agonists: evaluation of their adjuvancy and immunotherapeutic properties in a murine model of asthma
|
JOURNAL OF MEDICINAL CHEMISTRY |
Ponencia | 2023 |
Sistemas de transporte de genes basados en ciclooligosacáridos policatiónicos con capacidad de respuesta al pH y al potencial redox
|
XVI Congreso SEFIG ( 16. 2023. Madrid): Libro de comunicaciones |
Artículo | 2023 |
Synthesis, biological evaluation, and docking studies of open-chain carbohydrate amides as acetylcholinesterase inhibitors.
|
MEDICINAL CHEMISTRY |
Artículo | 2022 |
A beta-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells.
|
PHARMACEUTICS |
Artículo | 2022 |
Bicyclic picomolar OGA inhibitors enable chemoproteomic mapping of its endogenous post-translational modifications
|
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Artículo | 2022 |
Enhanced gene delivery triggered by dual pH/Redox responsive host-guest dimerization of cyclooligosaccharide star polycations.
|
Macromolecular rapid communications |
Artículo | 2022 |
Mannobioside biomimetics that trigger DC-SIGN binding selectivity.
|
CHEMICAL COMMUNICATIONS |
Artículo | 2022 |
sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease
|
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
Artículo | 2022 |
Stereoselective Synthesis of Nojirimycin α-C-Glycosides from a Bicyclic Acyliminium Intermediate: A Convenient Entry to N,C-Biantennary Glycomimetics
|
ACS OMEGA |
Artículo | 2022 |
Unravelling the Inflammatory Processes in the Early Stages of Diabetic Nephropathy and the Potential Effect of (S-s)-DS-ONJ
|
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Artículo | 2021 |
A versatile stereocontrolled synthesis of 2-deoxyiminosugarC-glycosides and their evaluation as glycosidase inhibitors
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2021 |
Anti-inflammatory (M2) response is induced by a sp(2)-iminosugar glycolipid sulfoxide in diabetic retinopathy
|
FRONTIERS IN IMMUNOLOGY |
Artículo | 2021 |
Rational design of cell active C2-modified DGJ analogues for the inhibition of human alpha-galactosidase A (GALA)
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2021 |
Synthesis of sp(2)-iminosugar selenoglycolipids as multitarget drug candidates with antiproliferative, leishmanicidal and anti-inflammatory properties
|
MOLECULES |
Artículo | 2021 |
Synthesis, self-assembly and anticancer drug encapsulation and delivery properties of cyclodextrin-based giant amphiphiles
|
CARBOHYDRATE POLYMERS |
Artículo | 2021 |
Trifaceted mickey mouse amphiphiles for programmable self-assembly, DNA complexation and organ-selective gene delivery.
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2020 |
Amplified Detection of Breast Cancer Autoantibodies Using MUC1-Based Tn Antigen Mimics
|
JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2020 |
Carbohydrate supramolecular chemistry: beyond the multivalent effect
|
CHEMICAL COMMUNICATIONS |
Artículo | 2020 |
Click synthesis of size- and shape-tunable star polymers with functional macrocyclic cores for synergistic DNA complexation and delivery
|
BIOMACROMOLECULES |
Revisión | 2020 |
Cyclodextrin-based functional glyconanomaterials
|
NANOMATERIALS |
Artículo | 2020 |
Cyclodextrin-Based Nanostructure Efficiently Delivers siRNA to Glioblastoma Cells Preferentially via Macropinocytosis
|
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Capítulo | 2020 |
sp2-Iminosugars as chemical mimics for glycodrug design
|
Small molecule drug discovery: methods, molecules and applications |
Artículo | 2020 |
Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Bronsted Acid-Type Organocatalysis
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2020 |
Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
|
CHEMICAL SCIENCE |
Artículo | 2020 |
Tuning the Topological Landscape of DNA–Cyclodextrin Nanocomplexes by Molecular Design
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2019 |
Dynamic Control of the Self-Assembling Properties of Cyclodextrins by the Interplay of Aromatic and Host-Guest Interactions
|
FRONTIERS IN CHEMISTRY |
Artículo | 2019 |
Multiply-linked cyclodextrin-aromatic hybrids: Caps, hinges and clips
|
JOURNAL OF CARBOHYDRATE CHEMISTRY |
Artículo | 2019 |
Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators
|
CHEMICAL COMMUNICATIONS |
Editorial | 2019 |
Novel Therapies for Orphan Diseases
|
ACS MEDICINAL CHEMISTRY LETTERS |
Artículo | 2019 |
Pharmacological Chaperones for the Treatment of alpha-Mannosidosis
|
JOURNAL OF MEDICINAL CHEMISTRY |
Resumen congreso | 2019 |
Screening sp(2)-iminosugar N-glycosides as pharmacological chaperone candidates for a mannosidosis: the effect of aglycone nature and valency
|
MOLECULAR GENETICS AND METABOLISM |
Artículo | 2019 |
sp(2)-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2019 |
Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2019 |
Tailoring the inhibitory versus chaperoning behavior of amphiphilic sp(2)-iminosugar glycomimetics targeting beta-glucocerebrosidase: From micromolar to picomolar chaperones for Gaucher disease
|
MOLECULAR GENETICS AND METABOLISM |
Artículo | 2019 |
Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp(2)-Iminosugar Glycolipids
|
MOLECULES |
Artículo | 2019 |
Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties
|
CHEMICAL COMMUNICATIONS |
Artículo | 2018 |
Catalyst-Free Synthesis of Alkylpolyglycosides Induced by High-Frequency Ultrasound
|
CHEMSUSCHEM |
Artículo | 2018 |
Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2018 |
Plasmid-Templated Control of DNA-Cyclodextrin Nanoparticle Morphology through Molecular Vector Design for Effective Gene Delivery
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2018 |
Probing the Inhibitor versus Chaperone Properties of sp(2)-Iminosugars towards Human beta-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease
|
MOLECULES |
Artículo | 2018 |
Revealing cooperative binding of polycationic cyclodextrins with DNA oligomers by capillary electrophoresis coupled to mass spectrometry
|
ANALYTICA CHIMICA ACTA |
Artículo | 2018 |
The sp(2)-iminosugar glycolipid 1-dodecylsulfony1-5N,6O-oxomethylidenenojirimycin (DSO2-ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explants
|
FOOD AND CHEMICAL TOXICOLOGY |
Artículo | 2018 |
Xylylene Clips for the Topology-Guided Control of the Inclusion and Self-Assembling Properties of Cyclodextrins
|
JOURNAL OF ORGANIC CHEMISTRY |
Resumen congreso | 2017 |
Inhibitors and effectors of the glycosidases as therapeutic tools
|
Biosaia |
Artículo | 2017 |
A novel potential nanophototherapeutic based on the assembly of an amphiphilic cationic beta-cyclodextrin and an anionic porphyrin
|
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES |
Artículo | 2017 |
Biophysics and protein corona analysis of Janus cyclodextrin-DNA nanocomplexes. Efficient cellular transfection on cancer cells
|
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS |
Artículo | 2017 |
Carbon Dioxide as a Traceless Caramelization Promotor: Preparation of Prebiotic Difructose Dianhydrides (DFAs)-Enriched Caramels from D-Fructose
|
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY |
Artículo | 2017 |
Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers
|
JOURNAL OF MATERIALS CHEMISTRY B |
Artículo | 2017 |
Development of polycationic amphiphilic cyclodextrin nanoparticles for anticancer drug delivery
|
BEILSTEIN JOURNAL OF NANOTECHNOLOGY |
Artículo | 2017 |
Docetaxel-Loaded Nanoparticles Assembled from beta-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells
|
FRONTIERS IN PHARMACOLOGY |
Artículo | 2017 |
Fluorinated Chaperone-beta-Cyclodextrin Formulations for beta-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease
|
JOURNAL OF MEDICINAL CHEMISTRY |
Ponencia | 2017 |
Fluorinated chaperone-beta-cyclodextrin formulations for neuronopathic Gaucher disease
|
MOLECULAR GENETICS AND METABOLISM |
Artículo | 2017 |
Molecular determinants for cyclooligosaccharide-based nanoparticle-mediated effective siRNA transfection
|
NANOMEDICINE |
Revisión | 2017 |
Molecular nanoparticle-based gene delivery systems
|
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY |
Artículo | 2017 |
Multivalency as an action principle in multimodal lectin recognition and glycosidase inhibition: a paradigm shift driven by carbon-based glyconanomaterials
|
JOURNAL OF MATERIALS CHEMISTRY B |
Artículo | 2017 |
sp(2)-Iminosugar -glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, 1-integrin, and FAK signaling pathways
|
JOURNAL OF CELLULAR PHYSIOLOGY |
Artículo | 2017 |
The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2016 |
Cholesterol-Targeted Anticancer and Apoptotic Effects of Anionic and Polycationic Amphiphilic Cyclodextrin Nanoparticles
|
JOURNAL OF PHARMACEUTICAL SCIENCES |
Artículo | 2016 |
Conformationally-locked C-glycosides: tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2016 |
Cyclodextrin-based facial amphiphiles: assessing the impact of the hydrophilic-lipophilic balance in the self-assembly, DNA complexation and gene delivery capabilities
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2016 |
Deciphering of polycationic carbohydrate based non-viral gene delivery agents by ESI-LTQ-Orbitrap using CID/HCD pairwise tandem mass spectrometry
|
RSC ADVANCES |
Artículo | 2016 |
Efficient stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc) and sp(2)-iminosugar conjugates: Novel hexosaminidase inhibitors with discrimination capabilities between the mature and precursor forms of the enzyme
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Corrección | 2016 |
Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of alpha-N-Linked Disaccharide Mimics (vol 11, pg 3306, 2009)
|
ORGANIC LETTERS |
Artículo | 2016 |
Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, G(M1)-gangliosidosis and Fabry diseases
|
CHEMICAL COMMUNICATIONS |
Artículo | 2016 |
Impact of Nonthermal Atmospheric Plasma on the Structure of Cellulose: Access to Soluble Branched Glucans
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2016 |
Influence of the configurational pattern of sp(2)-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties
|
CARBOHYDRATE RESEARCH |
Artículo | 2016 |
Inhibitor versus chaperone behaviour of D-fagomine, DAB and LAB sp2-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2016 |
Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice
|
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE |
Ponencia | 2016 |
pH-responsive pharmacological chaperones for lysosomal disease
|
MOLECULAR GENETICS AND METABOLISM |
Artículo | 2016 |
Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2016 |
Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody
|
ORGANIC LETTERS |
Artículo | 2016 |
Toward a suitable structural analysis of gene delivery carrier based on polycationic carbohydrates by electron transfer dissociation tandem mass spectrometry
|
ANALYTICA CHIMICA ACTA |
Artículo | 2016 |
Trehalose-based Janus cyclooligosaccharides: the "Click" synthesis and DNA-directed assembly into pH-sensitive transfectious nanoparticles
|
CHEMICAL COMMUNICATIONS |
Artículo | 2016 |
Understanding multivalent effects in glycosidase inhibition using C-glycoside click clusters as molecular probes
|
NEW JOURNAL OF CHEMISTRY |
Artículo | 2015 |
Antileishmanial activity of sp(2)-iminosugar derivatives
|
RSC ADVANCES |
Artículo | 2015 |
Cell uptake mechanisms of glycosylated cationic pDNA-cyclodextrin nanoparticles
|
RSC ADVANCES |
Artículo | 2015 |
Conformationally-locked N-glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2015 |
Correlations between changes in intestinal microbiota composition and performance parameters in broiler chickens
|
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION |
Artículo | 2015 |
Cyclodextrin- and calixarene-based polycationic amphiphiles as gene delivery systems: a structure-activity relationship study
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2015 |
Effects of feed additives on ileal mucosa-associated microbiota composition of broiler chickens
|
JOURNAL OF ANIMAL SCIENCE |
Artículo | 2015 |
Fluorinated hydroxypiperidines as selective beta-glucosidase inhibitors
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2015 |
Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery
|
RSC ADVANCES |
Artículo | 2015 |
Host-Guest-Mediated DNA Templation of Polycationic Supramolecules for Hierarchical Nanocondensation and the Delivery of Gene Material
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2015 |
Inhibition of type 1 fimbriae-mediated Escherichia coli adhesion and biofilm formation by trimeric cluster thiomannosides conjugated to diamond nanoparticles
|
NANOSCALE |
Artículo | 2015 |
pH-Responsive Pharmacological Chaperones for Rescuing Mutant Glycosidases
|
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION |
Artículo | 2015 |
Pharmacological Chaperones and Coenzyme Q(10) Treatment Improves Mutant beta-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
|
Scientific reports |
Artículo | 2015 |
Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2015 |
Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins?
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2015 |
Unprecedented inhibition of glycosidase-catalyzed substrate hydrolysis by nanodiamond-grafted Oglycosides
|
RSC ADVANCES |
Artículo | 2014 |
A Di-D-Fructose Dianhydride-Enriched Caramel Modulates Pig Fecal Microbiota Composition
|
ADVANCES IN MICROBIOLOGY |
Ponencia | 2014 |
A double diastereoselective Michael-type addition as an entry to Tn antigen mimics and analogs of Thiamet-G
|
XI Carbohydrate Symposium |
Ponencia | 2014 |
Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease
|
MOLECULAR GENETICS AND METABOLISM |
Artículo | 2014 |
Cyclodextrin-scaffolded amphiphilic aminoglucoside clusters: self-assembling and gene delivery capabilities
|
NEW JOURNAL OF CHEMISTRY |
Ponencia | 2014 |
Design of cationic amphiphilic carbohydrates as modulators of innate inmunity
|
XI Carbohydrate Symposium |
Artículo | 2014 |
Dynamic Self-Assembly of Polycationic Clusters Based on Cyclodextrins for pH-Sensitive DNA Nanocondensation and Delivery by Component Design
|
CHEMISTRY-A EUROPEAN JOURNAL |
Ponencia | 2014 |
Exploring the structural basis for glycosidase inhibition by multivalent glycomimetics: the "inhibitory multivalent effect"
|
XI Carbohydrate Symposium |
Artículo | 2014 |
Glycoligand-targeted core-shell nanospheres with tunable drug release profiles from calixarene-cyclodextrin heterodimers
|
CHEMICAL COMMUNICATIONS |
Ponencia | 2014 |
Glycosidase inhibitors and effectors as therapeutic tools
|
XI Carbohydrate Symposium |
Ponencia | 2014 |
Glycotargeted self-assembled nanocarriers from calixarene-cyclodextrin heterodimers for site-specific delivery of docetaxel
|
XI Carbohydrate Symposium |
Artículo | 2014 |
Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies
|
CHEMICAL COMMUNICATIONS |
Artículo | 2014 |
Molecular Basis of 1-Deoxygalactonojirimycin Arylthiourea Binding to Human alpha-Galactosidase A: Pharmacological Chaperoning Efficacy on Fabry Disease Mutants
|
ACS CHEMICAL BIOLOGY |
Corrección | 2014 |
Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds (vol 22, pg 633, 2013)
|
HUMAN MOLECULAR GENETICS |
Artículo | 2014 |
Structural Basis of Pharmacological Chaperoning for Human beta-Galactosidase
|
JOURNAL OF BIOLOGICAL CHEMISTRY |
Artículo | 2014 |
Synthesis of Multibranched Australine Derivatives from Reducing Castanospermine Analogues through the Amadori Rearrangement of gem-Diamine Intermediates: Selective Inhibitors of beta-Glucosidase
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2014 |
Synthesis of substituted exo-glucals via a modified Julia olefination and identification as selective beta-glucosidase inhibitors
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Ponencia | 2014 |
Tailoring self-assembling and targeting capabilities of CD-based nanoparticles for gene delivery
|
XI Carbohydrate Symposium |
Artículo | 2014 |
Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Corrección | 2014 |
Topological Effects and Binding Modes Operating with Multivalent Iminosugar-Based Glycoclusters and Mannosidases (vol 135, pg 18427, 2013)
|
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Artículo | 2014 |
Trehalose- and Glucose-Derived Glycoamphiphiles: Small-Molecule and Nanoparticle Toll-Like Receptor 4 (TLR4) Modulators
|
JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2013 |
A Bicyclic 1-Deoxygalactonojirimycin Derivative as a Novel Pharmacological Chaperone for GM(1) Gangliosidosis
|
MOLECULAR THERAPY |
Artículo | 2013 |
Amphiphilic Oligoethyleneimine-beta-Cyclodextrin "Click" Clusters for Enhanced DNA Delivery
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2013 |
Bicyclic Derivatives of L-Idonojirimycin as Pharmacological Chaperones for Neuronopathic Forms of Gaucher Disease
|
CHEMBIOCHEM |
Capítulo | 2013 |
Click Multivalent Glycomaterials: Glycoclusters, Glycodendrimers, Glycopolymers, Hybrid Glycomaterials, and Glycosurfaces
|
Click Chemistry in Glycoscience: New Developments and Strategies |
Artículo | 2013 |
Competitive processes of a chromophore modified alpha-cyclodextrin in the presence of a fluorescence polarity sensitive probe
|
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY |
Revisión | 2013 |
Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate-protein interactions
|
CHEMICAL SOCIETY REVIEWS |
Artículo | 2013 |
Cyclodextrin-scaffolded glycotransporters for gene delivery
|
PURE AND APPLIED CHEMISTRY |
Capítulo | 2013 |
Cyclodextrins for pharmaceutical and biomedical applications
|
SUPRAMOLECULAR SYSTEMS IN BIOMEDICAL FIELDS |
Artículo | 2013 |
Effects of inulin and di-D-fructose dianhydride-enriched caramels on intestinal microbiota composition and performance of broiler chickens
|
ANIMAL |
Ponencia | 2013 |
Folate-polycationic amphiphilic cyclodextrin-DNAnanocomplexes for gene delivery in vitro and in vivo
|
HUMAN GENE THERAPY |
Artículo | 2013 |
Fullerene-sp(2)-Iminosugar Balls as Multimodal Ligands for Lectins and Glycosidases: A Mechanistic Hypothesis for the Inhibitory Multivalent Effect
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2013 |
Influence of the Macroring Size on the Self-Association Thermodynamics of Cyclodextrins with a Double-Linked Naphthalene at the Secondary Face
|
JOURNAL OF PHYSICAL CHEMISTRY B |
Revisión | 2013 |
Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters, -glycopolymers and -glycoassemblies
|
CHEMICAL SOCIETY REVIEWS |
Artículo | 2013 |
N-Thiocarbonyl Iminosugars: Synthesis and Evaluation of Castanospermine Analogues Bearing Oxazole-2(3H)-thione Moieties
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2013 |
Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds
|
HUMAN MOLECULAR GENETICS |
Artículo | 2013 |
New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells
|
PLOS ONE |
Artículo | 2013 |
o-Xylylene Protecting Group in Carbohydrate Chemistry: Application to the Regioselective Protection of a Single vic-Diol Segment in Cyclodextrins
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2013 |
Probing the Nature of the Cluster Effect Observed with Synthetic Multivalent Galactosides and Peanut Agglutinin Lectin
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2013 |
Stereoselective Synthesis of 2-Acetamido-1,2-dideoxyallonojirimycin (DAJNAc), a New Potent Hexosaminidase Inhibitor
|
ORGANIC LETTERS |
Artículo | 2013 |
Targeted gene delivery by new folate-polycationic amphiphilic cyclodextrin-DNA nanocomplexes in vitro and in vivo
|
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS |
Artículo | 2013 |
The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Valency, Peripheral Ligand Structure, and Topology with Cyclodextrin-Based Iminosugar Click Clusters
|
CHEMBIOCHEM |
Artículo | 2013 |
Topological Effects and Binding Modes Operating with Multivalent Iminosugar-Based Glycoclusters and Mannosidases
|
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Ponencia | 2013 |
Use of the L-idonojirimycin derivatives as pharmacological chaperones for the treatment of Gaucher disease
|
MOLECULAR GENETICS AND METABOLISM |
Artículo | 2012 |
Conformationally-Locked N-Glycosides with Selective beta-Glucosidase Inhibitory Activity: Identification of a New Non-Iminosugar-Type Pharmacological Chaperone for Gaucher Disease
|
JOURNAL OF MEDICINAL CHEMISTRY |
Capítulo | 2012 |
Glycotransporters for gene delivery
|
CARBOHYDRATE CHEMISTRY: CHEMICAL AND BIOLOGICAL APPROACHES, VOL 38 |
Artículo | 2012 |
Improving inclusion capabilities of permethylated cyclodextrins by appending a cap-like aromatic moiety
|
TETRAHEDRON |
Artículo | 2012 |
Monodisperse Nanoparticles from Self-Assembling Amphiphilic Cyclodextrins: Modulable Tools for the Encapsulation and Controlled Release of Pharmaceuticals
|
MEDICINAL CHEMISTRY |
Artículo | 2012 |
Polycationic amphiphilic cyclodextrins as gene vectors: effect of the macrocyclic ring size on the DNA complexing and delivery properties
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2012 |
Probing Carbohydrate-Lectin Recognition in Heterogeneous Environments with Monodisperse Cyclodextrin-Based Glycoclusters
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2012 |
Scalable Syntheses of Both Enantiomers of DNJNAc and DGJNAc from Glucuronolactone: The Effect of N-Alkylation on Hexosaminidase Inhibition
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2012 |
sp2-Iminosugar O-, S-, and N-Glycosides as Conformational Mimics of a-Linked Disaccharides; Implications for Glycosidase Inhibition
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2012 |
Synthesis and glycosidase inhibitory activity of isourea-type bicyclic sp(2)-iminosugars related to galactonojirimycin and allonojirimycin
|
TETRAHEDRON |
Artículo | 2012 |
Tuning glycosidase inhibition through aglycone interactions: pharmacological chaperones for Fabry disease and GM(1) gangliosidosis
|
CHEMICAL COMMUNICATIONS |
Artículo | 2011 |
Amphiphilic 1-Deoxynojirimycin Derivatives through Click Strategies for Chemical Chaperoning in N370S Gaucher Cells
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2011 |
beta-Cyclodextrin-Based Polycationic Amphiphilic "Click" Clusters: Effect of Structural Modifications in Their DNA Complexing and Delivery Properties
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2011 |
Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards beta-glucocerebrosidase
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Revisión | 2011 |
Cyclodextrin-based gene delivery systems
|
CHEMICAL SOCIETY REVIEWS |
Artículo | 2011 |
Cyclodextrin-mediated crystallization of acid beta-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2011 |
Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery
|
BIOMATERIALS |
Revisión | 2011 |
Pharmacological chaperone therapy for Gaucher disease: a patent review
|
EXPERT OPINION ON THERAPEUTIC PATENTS |
Artículo | 2011 |
Polycationic amphiphilic cyclodextrin-based nanoparticles for therapeutic gene delivery
|
NANOMEDICINE |
Artículo | 2011 |
Stereoselective Synthesis of Difructose Dianhydrides by Use of the Xylylene Group as Stereodirecting Element in Spiroketalisation Reactions
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2011 |
Symmetry Complementarity-Guided Design of Anthrax Toxin Inhibitors Based on beta-Cyclodextrin: Synthesis and Relative Activities of Face-Selective Functionalized Polycationic Clusters
|
CHEMMEDCHEM |
Artículo | 2011 |
The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters with Cyclodextrin-based Iminosugar Click Clusters
|
CHEMISTRY-A EUROPEAN JOURNAL |
Revisión | 2010 |
(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties
|
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2010 |
A Fluorescent sp(2)-Iminosugar With Pharmacological Chaperone Activity for Gaucher Disease: Synthesis and Intracellular Distribution Studies
|
CHEMBIOCHEM |
Artículo | 2010 |
Comparative studies on lectin-carbohydrate interactions in low and high density homo- and heteroglycoclusters
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2010 |
Di-D-fructose Dianhydride-Enriched Caramels: Effect on Colon Microbiota, Inflammation, and Tissue Damage in Trinitrobenzenesulfonic Acid-Induced Colitic Rats
|
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY |
Artículo | 2010 |
Di-D-fructose Dianhydride-Enriched Products by Acid Ion-Exchange Resin-Promoted Caramelization of D-Fructose: Chemical Analyses
|
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY |
Revisión | 2010 |
Difructose Dianhydrides (DFAs) and DFA-Enriched Products as Functional Foods
|
CARBOHYDRATES IN SUSTAINABLE DEVELOPMENT I: RENEWABLE RESOURCES FOR CHEMISTRY AND BIOTECHNOLOGY |
Artículo | 2010 |
Fluorescent-tagged sp(2)-iminosugars with potent beta-glucosidase inhibitory activity
|
BIOORGANIC & MEDICINAL CHEMISTRY |
Artículo | 2010 |
Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect
|
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION |
Artículo | 2010 |
Insights in cellular uptake mechanisms of pDNA-polycationic amphiphilic cyclodextrin nanoparticles (CDplexes)
|
JOURNAL OF CONTROLLED RELEASE |
Artículo | 2010 |
Preorganized, Macromolecular, Gene-Delivery Systems
|
CHEMISTRY-A EUROPEAN JOURNAL |
Corrección | 2010 |
Preorganized, Macromolecular, GeneDelivery Systems (vol 16, pg 4907, 2010)
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2010 |
Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents
|
CHEMICAL COMMUNICATIONS |
Artículo | 2009 |
6-Amino-6-deoxy-5,6-di-N-(N '-octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid beta-Glucosidase
|
CHEMBIOCHEM |
Artículo | 2009 |
Chaperone Activity of Bicyclic Nojirimycin Analogues for Gaucher Mutations in Comparison with N-(n-nonyl)-Deoxynojirimycin
|
CHEMBIOCHEM |
Artículo | 2009 |
Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of alpha-N-Linked Disaccharide Mimics
|
ORGANIC LETTERS |
Artículo | 2009 |
Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2009 |
Multivalent iminosugars to modulate affinity and selectivity for glycosidases
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2009 |
Polycationic Amphiphilic Cyclodextrins for Gene Delivery: Synthesis and Effect of Structural Modifications on Plasmid DNA Complex Stability, Cytotoxicity, and Gene Expression
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2009 |
Preorganized macromolecular gene delivery systems: amphiphilic beta-cyclodextrin "click clusters"
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2009 |
Regioselective synthesis and biological evaluation of spiro-sulfamidate glycosides from exo-glycals
|
TETRAHEDRON-ASYMMETRY |
Artículo | 2009 |
Size-Tunable Trehalose-Based Nanocavities: Synthesis, Structure, and Inclusion Properties of Large-Ring Cyclotrehalans
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2009 |
Synthesis of Thiohydantoin-Castanospermine Glycomimetics as Glycosidase Inhibitors
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2009 |
Thermodynamics of the Dimer Formation of 2(I),3(I)-O-(o-Xylylene)-per-O-Me-gamma-cyclodextrin: Fluorescence, Molecular Mechanics and Molecular Dynamics
|
JOURNAL OF FLUORESCENCE |
Revisión | 2008 |
Chemical and enzymatic approaches to carbohydrate-derived spiroketals: Di-D-fructose dianhydrides (DFAs)
|
MOLECULES |
Artículo | 2008 |
Molecular Basis for beta-Glucosidase Inhibition by Ring-Modified Calystegine Analogues
|
CHEMBIOCHEM |
Artículo | 2008 |
Rational design of cationic cyclooligosaccharides as efficient gene delivery systems
|
CHEMICAL COMMUNICATIONS |
Artículo | 2008 |
Stereoselective synthesis of nonsymmetrical difructose dianhydrides from xylylene-tethered D-fructose precursors
|
TETRAHEDRON |
Artículo | 2008 |
Study of the Conformational and Self-Aggregation Properties of 2(I),3(I)-O-(o-Xylylene)-per-O-Me-alpha- and beta-cyclodextrins by Fluorescence and Molecular Modeling
|
JOURNAL OF PHYSICAL CHEMISTRY B |
Artículo | 2008 |
Synthesis and biological evaluation of guanidine-type iminosugars
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2008 |
Synthesis and evaluation of sulfamide-type indolizidines as glycosidase inhibitors
|
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS |
Artículo | 2008 |
Synthesis, structure, and inclusion capabilities of trehalose-based cyclodextrin analogues (Cyclotrehalans)
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2008 |
Tailoring beta-Cyclodextrin for DNA Complexation and Delivery by Homogeneous Functionalization at the Secondary Face
|
ORGANIC LETTERS |
Ponencia | 2008 |
Targeted beta-cyclodextrine-based gene delivery systems: Physicochemical and transfection studies
|
HUMAN GENE THERAPY |
Artículo | 2007 |
Efficient use of Ellman safety-catch linker for solid-phase assisted synthesis of multivalent glycoconjugates
|
JOURNAL OF COMBINATORIAL CHEMISTRY |
Artículo | 2007 |
Les cyclodextrines en pharmacie: Perspectives pour le ciblage d actifs thérapeutiques et le contrôle d interactions membranaires || Pharmaceutical use of cyclodextrines: Perspectives for drug targeting and control of membrane interactions
|
Annales Pharmaceutiques Françaises |
Artículo | 2007 |
Multi-mannosides based on a carbohydrate scaffold: Synthesis, force field development, molecular dynamics studies, and binding affinities for lectin Con A
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2007 |
One-pot regioselective synthesis of 2(I),3(I)-O-(o-xylylene)-capped cyclomaltooligosaccharides: tailoring the topology and supramolecular properties of cyclodextrins
|
CHEMICAL COMMUNICATIONS |
Artículo | 2007 |
Promoting helicity in carbohydrate-containing foldamers through long-range hydrogen bonds
|
CHEMICAL COMMUNICATIONS |
Artículo | 2007 |
Spacer-mediated synthesis of bis-spiroketal disaccharides: Nonsymmetrical furanose-pyranose difructose dianhydrides
|
SYNLETT |
Artículo | 2007 |
Synthesis and biological evaluation of 6-oxa-nor-tropane glycomimetics as glycosidase inhibitors
|
TETRAHEDRON |
Artículo | 2007 |
Synthesis of alpha- and beta-glycosyl isothiocyanates via oxazoline intermediates
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2007 |
Synthesis of thiourea-linked glycooligomers that mimic the branching patterns of natural oligosaccharides
|
SYNTHESIS-STUTTGART |
Artículo | 2007 |
Trehalose-based cyclodextrin analogs: cyclotrehalans (CTs)
|
Journal of Inclusion Phenomena and Macrocyclic Chemistry |
Artículo | 2006 |
Glyconanocavities: Cyclodextrins and beyond
|
Journal of Inclusion Phenomena and Macrocyclic Chemistry |
Artículo | 2006 |
Intramolecular benzyl protection delivery: A practical synthesis of DMDP and DGDP from D-fructose
|
ORGANIC LETTERS |
Artículo | 2006 |
Spacer-mediated synthesis of contra-thermodynamic spiroacetals: Stereoselective synthesis of C-2-symmetric difructose dianhydrides
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2006 |
The o-xylylene protecting group as an element of conformational control of remote stereochemistry in the synthesis of spiroketals
|
CHEMICAL COMMUNICATIONS |
Artículo | 2006 |
The synthesis and structure of linear and dendritic thiourea-linked glycooligomers
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2006 |
Urea-, thiourea-, and guanidine-linked glycooligomers as phosphate binders in water
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2005 |
1,2,3-Triazoles and related glycoconjugates as new glycosidase inhibitors
|
TETRAHEDRON |
Capítulo | 2005 |
Identificación y cuantificación de azúcares resultantes de la dimerización de la sacarosa y de la d-fructosa (dianhídricos de fructosa) formados en la raíz de remolacha o durante su procesado industrial
|
Aspectos fisiológicos de la remolacha azucarera de siembra otoñal |
Artículo | 2005 |
Probing secondary carbohydrate-protein interactions with highly dense cyclodextrin-centered heteroglycoclusters: The heterocluster effect
|
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Artículo | 2005 |
Rigid spacer-mediated synthesis of bis-spiroketal ring systems: stereoselective synthesis nonsymmetrical spiro of disaccharides
|
ORGANIC LETTERS |
Artículo | 2005 |
Synthesis and comparative glycosidase inhibitory properties of reducing castanospermine analogues
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2004 |
A general entry to linear, dendritic and branched thiourea-linked glycooligomers as new motifs for phosphate ester recognition in water
|
CHEMICAL COMMUNICATIONS |
Artículo | 2004 |
Carbohydrate-derived spiroketals: stereoselective synthesis of di-D-fructose dianhydrides
|
TETRAHEDRON |
Artículo | 2004 |
Functional evaluation of carbohydrate-centred glycoclusters by enzyme-linked lectin assay: Ligands for concanavalin A
|
CHEMBIOCHEM |
Artículo | 2004 |
Optimizing saccharide-directed molecular delivery to biological receptors: Design, synthesis, and biological evaluation of glycodendrimer - Cyclodextrin conjugates
|
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Artículo | 2004 |
Pseudoamide-type pyrrolidine and pyrrolizidine glycomimetics and their inhibitory activities against glycosidases
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2004 |
Synthesis of calystegine B-2, B-3, and B-4 analogues: Mapping the structure-glycosidase inhibitory activity relationships in the 1-deoxy-6-oxacalystegine series
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2004 |
Synthesis of sugar oxazolines by intramolecular Ritter-like reaction of D-fructose precursors
|
SYNLETT |
Artículo | 2003 |
Carbohydrate-derived spiroketals: Stereoselective synthesis of di-D-fructose dianhydrides via intramolecular aglycon delivery
|
ORGANIC LETTERS |
Artículo | 2003 |
Synthesis and evaluation of isourea-type glycomimetics related to the indolizidine and trehazolin glycosidase inhibitor families
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2003 |
Synthesis of (1S,2S,3R,8S,8aR)-1,2,3,8-tetrahydroxy-6-oxa-5-thioxoindolizidine: A stable reducing swainsonine analog with controlled anomeric configuration
|
SYNLETT |
Artículo | 2002 |
Carbohydrate microarrays
|
CHEMBIOCHEM |
Artículo | 2002 |
Castanospermine-trehazolin hybrids: a new family of glycomimetics with tuneable glycosidase inhibitory properties
|
CHEMICAL COMMUNICATIONS |
Artículo | 2002 |
Cyclotrehalins: Cyclooligosaccharide receptors featuring a hydrophobic cavity
|
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION |
Corrección | 2002 |
Erratum: (Angewandte Chemie - International Edition (2002) 19 (3674-3676))
|
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION |
Artículo | 2002 |
Multivalent cyclooligosaccharides: Versatile carbohydrate clusters with dual role as molecular receptors and lectin ligands
|
CHEMISTRY-A EUROPEAN JOURNAL |
Artículo | 2002 |
One-step synthesis of non-anomeric sugar isothiocyanates from sugar azides
|
CARBOHYDRATE RESEARCH |
Artículo | 2001 |
Carbohydrate-based receptors with multiple thiourea binding sites. Multipoint hydrogen bond recognition of dicarboxylates and monosaccharides
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2001 |
Carbohydrate-derived spiroketals. stereoselective synthesis of di-D-fructose dianhydrides by boron trifluoride promoted glycosylation-spiroketalization of acetal precursors
|
ORGANIC LETTERS |
Artículo | 2001 |
Dependence of concanavalin A binding on anomeric configuration, linkage type, and ligand multiplicity for thiourea-bridged mannopyranosyl-beta-cyclodextrin conjugates
|
CHEMBIOCHEM |
Artículo | 2001 |
Synthesis and evaluation of calystegine B-2 analogues as glycosidase inhibitors
|
JOURNAL OF ORGANIC CHEMISTRY |
Revisión | 2000 |
Chemistry and developments of N-thiocarbonyl carbohydrate derivatives: Sugar isothiocyanates, thioamides, thioureas, thiocarbamates, and their conjugates
|
ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL 55 |
Artículo | 2000 |
Generalized anomeric effect in action: Synthesis and evaluation of stable reducing indolizidine glycomimetics as glycosidase inhibitors
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2000 |
Nitrogen versus sulfur acylation in sugar thioureas: regioselectivity and conformational consequences
|
TETRAHEDRON-ASYMMETRY |
Artículo | 2000 |
Synthesis and comparative lectin-binding affinity of mannosyl-coated beta-cyclodextrin-dendrimer constructs
|
CHEMICAL COMMUNICATIONS |
Artículo | 2000 |
Synthesis of glycosyl(thio)ureido sugars via carbodiimides and their conformational behaviour in water
|
CARBOHYDRATE RESEARCH |
Artículo | 1999 |
A practical amine-free synthesis of symmetric ureas and thioureas by self-condensation of iso(thio)cyanates
|
SYNTHESIS-STUTTGART |
Ponencia | 1999 |
Investigation of the inclusion complex and stoichiometry of omeprazole with beta-CD by H-1 NMR spectroscopy
|
PROCEEDINGS OF THE 9TH INTERNATIONAL SYMPOSIUM ON CYCLODEXTRINS |
Artículo | 1999 |
Polyhydroxylated N-(thio)carbamoyl piperidines: nojirimycin-type glycomimetics with controlled anomeric configuration
|
TETRAHEDRON-ASYMMETRY |
Artículo | 1999 |
S-linked thiomimetics of phytoalexin-elicitor-active, branched oligosaccharides, their synthesis, protein-binding ability and phytoalexin-inducing activity
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 1999 |
Sugar thioureas as anion receptors. Effect of intramolecular hydrogen bonding in the carboxylate binding properties of symmetric sugar thioureas
|
ORGANIC LETTERS |
Artículo | 1999 |
Synthesis and anomeric stability of (1 -> 6)-thiourea-linked pseudooligosaccharides
|
CARBOHYDRATE RESEARCH |
Artículo | 1999 |
Synthesis of 6,7-dideoxy-7-isothiocyanatoheptoses: Stable fully unprotected monosaccharide isothiocyanates
|
CARBOHYDRATE RESEARCH |
Ponencia | 1999 |
Thiourea-bridged beta-cyclodextrin conjugates
|
PROCEEDINGS OF THE 9TH INTERNATIONAL SYMPOSIUM ON CYCLODEXTRINS |
Artículo | 1998 |
Cyclodextrin-scaffolded glycoclusters
|
CHEMISTRY-A EUROPEAN JOURNAL |
Ponencia | 1998 |
Macrocyclic sugar thioureas: Cyclooligosaccharides mimicking cyclopeptides
|
MOLECULAR RECOGNITION AND INCLUSION |
Artículo | 1998 |
Sulfur atom participation in thiooligosaccharide chemistry: Synthesis of 1 '-thiotrehalulose and 1 '-epi-thiotrehalulose and comparative reactivity with the O-linked disaccharide analogue, trehalulose
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 1998 |
Synthesis and stereoelectronic properties of sugar-shaped polyhydroxylated hexahydropyrimidine-2-thiones
|
TETRAHEDRON |
Artículo | 1998 |
Synthesis of calystegine B2 analogs by tandem tautomerization-intramolecular glycosylation of thioureidosugars
|
SYNLETT |
Ponencia | 1998 |
Thioureido beta-cyclodextrins as molecular carriers for the anticancer drug Taxotere (R)
|
MOLECULAR RECOGNITION AND INCLUSION |
Artículo | 1997 |
Aza-Wittig reaction of sugar isothiocyanates and sugar iminophosphoranes: An easy entry to unsymmetrical sugar carbodiimides
|
TETRAHEDRON LETTERS |
Artículo | 1997 |
N-thiocarbonyl azasugars: a new family of carbohydrate mimics with controlled anomeric configuration
|
CHEMICAL COMMUNICATIONS |
Artículo | 1997 |
Synthesis of (1 → 6)-carbodiimide-tethered pseudooligosaccharides via aza-Wittig reaction
|
CARBOHYDRATE RESEARCH |
Artículo | 1996 |
Conformational energetics of sugar thioureas and synthesis of glycosyl thioureido sugars
|
TETRAHEDRON |
Artículo | 1996 |
Influence of intramolecular hydrogen-bonding on the conformation of 3-deoxy-3-thioureido sugars
|
CARBOHYDRATE RESEARCH |
Artículo | 1996 |
Stereocontrolled synthesis of sulfur-linked analogues of the branched tetrasaccharide repeating-unit of the immunostimulant polysaccharide schizophyllan and of its beta-(1->3)-branched, beta-(1->6)-linked isomer
|
CARBOHYDRATE RESEARCH |
Artículo | 1996 |
Synthesis of sulfur-linked analogues of nigerose, laminarabiose, laminaratriose, gentiobiose, gentiotriose, and laminaran trisaccharide Y
|
CARBOHYDRATE RESEARCH |
Artículo | 1996 |
Tautomeric rearrangement of 3-deoxy-3-thioureidoaldoses: A novel synthetic route to carbohydrate mimics having a cyclic thiourea structure
|
CHEMICAL COMMUNICATIONS |
Artículo | 1996 |
Thioureido-beta-cyclodextrins as molecular carriers
|
CHEMICAL COMMUNICATIONS |
Nota | 1995 |
A mild and efficient procedure to remove acetal and dithioacetal protecting groups in carbohydrate-derivatives using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone
|
CARBOHYDRATE RESEARCH |
Artículo | 1995 |
Isothiocyanoates and cyclic thiocarbamates of alpha,alpha'-trehalose sucrose, and cyclomaltooligosaccharides
|
CARBOHYDRATE RESEARCH |
Artículo | 1995 |
O-acetyl protection of 6-aminoaldopyranosides and 1-aminoalditols
|
JOURNAL OF CARBOHYDRATE CHEMISTRY |
Artículo | 1995 |
Synthesis, conformational flexibility and preliminary complexation behavior of alpha,alpha'-trehalose-based macrocycles containing thiourea spacers
|
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS |
Nota | 1994 |
1-deoxy-1-isothiocyanato-d-fructose as intermediate in syntheses of 1,3-o(s),n-heterocycles
|
CARBOHYDRATE RESEARCH |
Nota | 1994 |
A d-ribofuranosylenamine as glycosyl acceptor
|
CARBOHYDRATE RESEARCH |
Artículo | 1994 |
Enantiopure 2-thioxotetrahydro-1,3-o,n-heterocycles from carbohydrates .3. enantiopure c-4 chiral oxazine-2-thiones and oxazolidine-2-thiones from 3-deoxy-3-isothiocyanato sugars
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 1994 |
Influence of intramolecular hydrogen-bonding on the conformational properties of sugar thioureas
|
TETRAHEDRON-ASYMMETRY |
Artículo | 1994 |
Synthesis and conformational properties of sugar amides and thioamides
|
TETRAHEDRON-ASYMMETRY |
Artículo | 1993 |
A cyclization-trapping route to carbocyclic and heterocyclic benzylic sulfones
|
TETRAHEDRON LETTERS |
Artículo | 1993 |
Building-blocks for glycopeptide synthesis - disaccharide glycosyl isothiocyanates
|
JOURNAL OF CARBOHYDRATE CHEMISTRY |
Artículo | 1993 |
Chiral 2-Thioxotetrahydro-1,3-O,N-heterocycles from Carbohydrates. 2. Stereocontrolled Synthesis of Oxazolidine Pseudo-C-nucleosides and Bicyclic Oxazine-2-thiones
|
JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 1992 |
Chiral 2-thioxotetrahydro-1,3-o,n-heterocycles from carbohydrates
|
TETRAHEDRON LETTERS |
Artículo | 1992 |
Glucosylenamines as glycosyl acceptors - synthesis of gentiobiosylenamines
|
CARBOHYDRATE RESEARCH |
Artículo | 1992 |
Partially protected d-glucopyranosyl isothiocyanates - synthesis and transformations into thiourea and heterocyclic-derivatives
|
TETRAHEDRON |
Artículo | 1992 |
Syntheses of β-iodourea derivatives of carbohydrates and glycosylamino-oxazolines
|
CARBOHYDRATE RESEARCH |
Artículo | 1991 |
Syntheses and spectral properties of beta-iodoureas and 2-amino-4,4-diphenyl-2-oxazolines
|
JOURNAL OF HETEROCYCLIC CHEMISTRY |
Artículo | 1991 |
Syntheses of beta-iodourea derivatives of carbohydrates and glycosylamino-oxazolines
|
CARBOHYDRATE RESEARCH |
Artículo | 1990 |
N-glycosyl-N'-carbonylmethylthioureas
|
Anales de Química |
Artículo | 1990 |
Regioselective benzoylations of d-xylopyranosylenamines and d-ribopyranosylenamines
|
Journal of Chemical Research |
Artículo | 1990 |
Synthesis of n-hetarylthiourea derivatives of carbohydrates
|
JOURNAL OF CARBOHYDRATE CHEMISTRY |
Artículo | 1989 |
Regioselective benzoylations of glycopyranosylamines: synthesis of partially protected glycopyranosyl isothiocyanates
|
CARBOHYDRATE RESEARCH |
Nota | 1989 |
Thiourea derivatives of carbohydrates .13. Syntheses of partially protected d-galactopyranosylthioureas - new d-galactopyranosylimidazoline-2-thiones and d-galactopyranosylaminothiazoles
|
CARBOHYDRATE RESEARCH |
Artículo | 1988 |
Syntheses of d-ribosylamines, d-ribopyranosyl isothiocyanates, and d-ribopyranosylthioureas, and their transformations into heterocyclic compounds
|
CARBOHYDRATE RESEARCH |
Artículo | 1988 |
Thiourea derivatives of carbohydrates .12. Syntheses of d-ribosylamines, d-ribopyranosyl isothiocyanates, and d-ribopyranosylthioureas, and their transformations into heterocyclic-compounds
|
CARBOHYDRATE RESEARCH |
Nota | 1987 |
Glycosil aminothiazole derivatives of d-glucosamina and d-galactose
|
ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA |
Artículo | 1987 |
Phenacylthiourea and N-thiazolyl derivatives of 2-amino-2-deoxy-d-glucose
|
CARBOHYDRATE RESEARCH |
Nota | 1987 |
Thiourea derivatives of carbohydrates .10. Phenacylthiourea and n-thiazolyl derivatives of 2-amino-2-deoxy-d-glucose
|
CARBOHYDRATE RESEARCH |
Artículo | 1986 |
Synthesis of 1,3,4,6-tetra-O-acetyl-2-[3-alkyl-(aryl)-thioreido]-2-deoxy-α-d-glucopyranoses and their transformation into 2-alkyl(aryl)amino-(1,2-dideoxy-α-d-glucopyrano)[2,1-d]-2-thiazolines
|
CARBOHYDRATE RESEARCH |
Artículo | 1986 |
Thiourea derivatives of carbohydrates .6. Synthesis of 1,3,4,6-tetra-o-acetyl-2-[3-alkyl(aryl)-thioureido]-2-deoxy-alpha-d-glucopyranoses and their transformation into 2-alkyl(aryl)amino-(1,2-dideoxy-alpha-d-glucopyrano)[2,1-d]-2-thiazolines
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CARBOHYDRATE RESEARCH |
Nota | 1986 |
Thiourea derivatives of carbohydrates .7. Synthesis of glycosylaminothiazoles
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CARBOHYDRATE RESEARCH |
Artículo | 1984 |
Thioureas derivatives of carbohydrates .4. Reaction of glycosylisothiothyanates and alpha-aminoketones hydrochlorides
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ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA |
Artículo | 1984 |
Tioureas derivadas de carbohidratos. IV. Reacción de glicosilisotiocianatos con ∝-aminocetonas hidrocloruros
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ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA |
Artículo | 1983 |
Thioureas derivatives of carbohydrates .3. Synthesis of glucosylthioureas and thioureas derivatives of d-glucosamine
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ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA |
Artículo | 1983 |
Tioureas derivadas de carbohidratos III. Síntesis de glucosiltioureas y de nuevas tioureas derivadas de la D-glucosamina
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Anales de la Real Sociedad Española de Química |