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Ver Investigador - - Prisma - Unidad de Bibliometría

Gonzalo De Gonzalo Calvo

Profesor Titular de Universidad
gdegonzalo@us.es
Área de conocimiento: Química Orgánica
Departamento: Química Orgánica
Grupo: SINTESIS ESTEREOSELECTIVA - FQM-263 (Universidad de Sevilla)
Prog. doctorado: QUÍMICA

Investiga en

Palabras clave
Líneas de investigación
Resumen
Tipo Año Título Fuente
Artículo2024 Asymmetric Sulfoxidations Catalyzed by Bacterial Flavin-Containing Monooxygenases MOLECULES
Artículo2024 Atroposelective Synthesis of 2-(Quinolin-8-yl)benzyl Alcohols by Biocatalytic Dynamic Kinetic Resolutions ADVANCED SYNTHESIS & CATALYSIS
Revisión2024 Deep eutectic solvents as catalysts in the synthesis of active pharmaceutical ingredients and precursors CATALYSTS
Artículo2024 Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases CELL REPORTS
Artículo2024 Sulphoxidation reactions catalysed by the Baeyer-Villiger monooxygenase OTEMO from Pseudomonas putida ATCC 17453 Biocatalysis and Biotransformation
Artículo2023 Biocatalytic Atroposelective Synthesis of Axially Chiral N-Arylindoles via Dynamic Kinetic Resolution ACS CATALYSIS
Revisión2023 Green oxidative catalytic processes for the preparation of APIs and precursors CATALYSTS
Artículo2023 Kinetic resolution of racemic benzofused alcohols catalysed by HMFO variants in presence of natural deep eutectic solvents Biocatalysis and Biotransformation
Revisión2022 Application of biobased solvents in asymmetric catalysis MOLECULES
Artículo2022 Biocatalysed reductions of α-ketoesters employing CyreneTM as cosolvent Biocatalysis and Biotransformation
Artículo2022 Biocatalysis for the asymmetric synthesis of Active Pharmaceutical Ingredients (APIs): this time is for real Expert Opinion on Drug Discovery
Capítulo2022 Enzyme-catalyzed asymmetric synthesis Catalytic Asymmetric Synthesis
Editorial2021 25th anniversary of molecules-recent advances in green chemistry MOLECULES
Libro2021 Biocatalysis for Practitioners: Techniques, Reactions and Applications Biocatalysis for Practitioners: Techniques, Reactions and Applications
Capítulo2021 Enzymatic Commercial Sources Biocatalysis for Practitioners: Techniques, Reactions and Applications
Revisión2021 Multienzymatic processes involving baeyer–villiger monooxygenases CATALYSTS
Revisión2021 Recent developments in the synthesis of β-diketones PHARMACEUTICALS
Revisión2021 Recent trends in synthetic enzymatic cascades promoted by alcohol dehydrogenases Current Opinion in Green and Sustainable Chemistry
Artículo2021 Room temperature ionic liquids in asymmetric hetero-ene type reactions: improving organocatalyst performance at lower temperatures MOLECULES
Revisión2020 Biocatalyzed Redox Processes Employing Green Reaction Media MOLECULES
Revisión2020 Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis ADVANCED SYNTHESIS & CATALYSIS
Artículo2020 Positive impact of natural deep eutectic solvents on the biocatalytic performance of 5-hydroxymethyl-furfural oxidase CATALYSTS
Revisión2019 Biocatalysis as useful tool in asymmetric synthesis: An assessment of recently granted patents(2014-2019) CATALYSTS
Artículo2019 Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using Pd-0-CalB CLEA as a Biohybrid Catalyst CHEMISTRY-A EUROPEAN JOURNAL
Revisión2019 Cyclopentyl Methyl Ether (CPME): A Versatile Eco-Friendly Solvent for Applications in Biotechnology and Biorefineries CHEMSUSCHEM
Artículo2019 P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules CATALYSTS
Artículo2018 Enantioselective sulfoxidations employing the thermostable cyclohexanone monooxygenase from Thermocrispum municipale ENZYME AND MICROBIAL TECHNOLOGY
Artículo2018 Fingerprinting the Nature of Anions in Pyrylium Complexes: Dual Binding Mode for Anion-pi Interactions CHEMPHYSCHEM
Artículo2018 Lipase catalysed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center MOLECULES
Corrección2018 Lipase Catalysed Kinetic Resolution of Racemic 1,2-Diols Containing a Chiral Quaternary Center (vol 23, 1585, 2018) MOLECULES
Editorial2018 Preface Biocatalysis: An Industrial Perspective
Artículo2018 Preparation of chitosan-supported urea materials and their application in some organocatalytic procedures CARBOHYDRATE POLYMERS
Revisión2018 Recent Developments on Supported Hydrogen-bond Organocatalysts CHEMCATCHEM
Artículo2018 Stereoselective enzymatic reduction of 1,4-diaryl-1,4-diones to the corresponding diols employing alcohol dehydrogenases CATALYSTS
Artículo2017 Asymmetric organocatalytic synthesis of tertiary azomethyl alcohols: key intermediates towards azoxy compounds and alpha-hydroxy-beta-amino esters ORGANIC & BIOMOLECULAR CHEMISTRY
Revisión2017 Organocatalysis and Biocatalysis Hand in Hand: Combining Catalysts in One-Pot Procedures ADVANCED SYNTHESIS & CATALYSIS
Artículo2017 Polycyclic ketone monooxygenase (PockeMO): A robust biocatalyst for the synthesis of optically active sulfoxides CATALYSTS
Revisión2016 Bacterial enzymes involved in lignin degradation JOURNAL OF BIOTECHNOLOGY
Artículo2016 Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst CHEMBIOCHEM
Ponencia2016 Immobilization of Baeyer-Villiger monooxygenases in presence of ionic liquids, a simple approach for enzyme recycling. 20TH INTERNATIONAL ELECTRONIC CONFERENCE ON SYNTHETIC ORGANIC CHEMISTRY (ECSOC)
Capítulo2016 Recent Developments in Flavin-Based Catalysis: Enzymatic Sulfoxidation Green Biocatalysis
Artículo2014 Asymmetric chemoenzymatic synthesis of N-acetyl-alpha-amino esters based on lipase-catalyzed kinetic resolutions through interesterification reactions TETRAHEDRON
Artículo2014 Regioselective preparation of thiamphenicol esters through lipase-catalyzed processes JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
Artículo2013 Expanding the biocatalytic toolbox of flavoprotein monooxygenases from Rhodococcus jostii RHA1 JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Revisión2013 Flavoprotein oxidases: classification and applications APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Otros2013 Recent Developments in Flavin-based Catalysis CHEMCATCHEM
Artículo2012 Access to Enantiopure α-Alkyl-β-hydroxy Esters through Dynamic Kinetic Resolutions Employing Purified/Overexpressed Alcohol Dehydrogenases ADVANCED SYNTHESIS & CATALYSIS
Artículo2012 Aspergillus genus as a source of new catalysts for sulfide oxidation JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2012 Blending Baeyer-Villiger monooxygenases: using a robust BVMO as a scaffold for creating chimeric enzymes with novel catalytic properties CHEMICAL COMMUNICATIONS
Artículo2012 Expanding the set of rhodococcal Baeyer-Villiger monooxygenases by high-throughput cloning, expression and substrate screening APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Artículo2012 Immobilized redox enzymatic catalysts: Baeyer-Villiger monooxygenases supported on polyphosphazenes JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2012 Improvement of the biocatalytic properties of one phenylacetone monooxygenase mutant in hydrophilic organic solvents ENZYME AND MICROBIAL TECHNOLOGY
Artículo2012 New Trends in Organic Synthesis with Oxidative Enzymes CURRENT ORGANIC CHEMISTRY
Artículo2012 Optimization of oxidative bioconversions catalyzed by phenylacetone monooxygenase from Thermobifida fusca JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Editorial2012 Recent Advances in Biocatalyzed Oxidations for the Synthesis of High Added Value Compounds CURRENT ORGANIC CHEMISTRY
Artículo2011 Cofactor regeneration in polymersome nanoreactors: enzymatically catalysed Baeyer-Villiger reactions JOURNAL OF MATERIALS CHEMISTRY
Artículo2011 Dynamic Kinetic Resolution of alpha-Substituted beta-Ketoesters Catalyzed by Baeyer-Villiger Monooxygenases: Access to Enantiopure alpha-Hydroxy Esters ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Artículo2011 Effects of Water Miscible Organic Solvents on the Activity and Conformation of the Baeyer-Villiger Monooxygenases From Thermobifida fusca and Acinetobacter calcoaceticus: A Comparative Study BIOTECHNOLOGY AND BIOENGINEERING
Artículo2011 Enzymatic regioselective production of chloramphenicol esters TETRAHEDRON
Artículo2011 Exploring the biocatalytic scope of a bacterial flavin-containing monooxygenase ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2011 Mapping the Substrate Binding Site of Phenylacetone Monooxygenase from Thermobifida fusca by Mutational Analysis APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Capítulo2011 Recent Advances in Biocatalysis Applied to Organic Synthesis Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications
Artículo2011 Selective oxidations of organoboron compounds catalyzed by Baeyer-Villiger monooxygenases ADVANCED SYNTHESIS & CATALYSIS
Artículo2011 Turning a riboflavin-binding protein into a self-sufficient monooxygenase by cofactor redesign CHEMICAL COMMUNICATIONS
Artículo2010 Biocatalysed concurrent production of enantioenriched compounds through parallel interconnected kinetic asymmetric transformations ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2010 Bioreduction of prochiral ketones by growing cells of Lasiodiplodia theobromae: Discovery of a versatile biocatalyst for asymmetric synthesis JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2010 BVMO-catalysed dynamic kinetic resolution of racemic benzyl ketones in the presence of anion exchange resins ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2010 Candida tropicalis CE017: a New Brazilian Enzymatic Source for the Bioreduction of Aromatic Prochiral Ketones JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
Artículo2010 Chemoenzymatic Synthesis of Substituted 1H-Inden-1-ones Using Lipases SYNTHESIS-STUTTGART
Artículo2010 Enzymatic Synthesis of Novel Chiral Sulfoxides Employing Baeyer-Villiger Monooxygenases EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2010 Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Artículo2010 Ionic liquids for enhancing the enantioselectivity of isolated BVMO-catalysed oxidations GREEN CHEMISTRY
Artículo2010 Oxidoreductases Working Together: Concurrent Obtaining of Valuable Derivatives by Employing the PIKAT Method CHEMCATCHEM
Revisión2010 Recent Developments in the Application of Baeyer-Villiger Monooxygenases as Biocatalysts CHEMBIOCHEM
Artículo2010 Reduction processes biocatalyzed by Vigna unguiculata TETRAHEDRON-ASYMMETRY
Artículo2010 Synthesis of Chiral 3-Alkyl-3,4-dihydroisocoumarins by Dynamic Kinetic Resolutions Catalyzed by a Baeyer-Villiger Monooxygenase JOURNAL OF ORGANIC CHEMISTRY
Artículo2009 Baeyer-Villiger monooxygenase-catalyzed kinetic resolution of racemic alpha-alkyl benzyl ketones: enzymatic synthesis of alpha-alkyl benzylketones and alpha-alkyl benzylesters TETRAHEDRON-ASYMMETRY
Artículo2009 Chemoenzymatic preparation of a biologically active naphthoquinone from Tabebuia impetiginosa using lipases or alcohol dehydrogenases JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2009 Chemoenzymatic synthesis of optically active Mugetanol isomers: use of lipases and oxidoreductases in fragrance chemistry TETRAHEDRON-ASYMMETRY
Artículo2009 Enantioselective acetylation of racemic alcohols by Manihot esculenta and Passiflora edulis preparations JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2009 Enzymatic Baeyer-Villiger Oxidation of Benzo-Fused Ketones: Formation of Regiocomplementary Lactones EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2009 Lentinus strigellus: a new versatile stereoselective biocatalyst for the bioreduction of prochiral ketones TETRAHEDRON-ASYMMETRY
Ponencia2009 Regioselective dynamic kinetic resolution of alkyl indanones by novel Baeyer-Villiger monooxygenases NEW BIOTECHNOLOGY
Artículo2008 Bioreduction of aromatic aldehydes and ketones by fruits' barks of Passiflora edulis JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2008 Immobilized Manihot esculenta preparation as a novel biocatalyst in the enantioselective acetylation of racemic alcohols TETRAHEDRON-ASYMMETRY
Artículo2008 Selective Baeyer-Villiger oxidation of racemic ketones in aqueous-organic media catalyzed by phenylacetone monooxygenase TETRAHEDRON-ASYMMETRY
Artículo2007 Asymmetric biocatalytic reduction of ketones using hydroxyl-functionalised water-miscible ionic liquids as solvents TETRAHEDRON-ASYMMETRY
Artículo2007 Enzymatic kinetic resolution of racemic ketones catalyzed by Baeyer-Villiger monooxygenases TETRAHEDRON-ASYMMETRY
Artículo2007 Enzymatic reduction of ketones in "micro-aqueous" media catalyzed by ADH-A from Rhodococcus ruber ORGANIC LETTERS
Artículo2007 Titration and assignment of residues that regulate the enantioselectivity of phenylacetone monooxygenase ADVANCED SYNTHESIS & CATALYSIS
Artículo2006 4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB as an oxidative biocatalyst in the synthesis of optically active sulfoxides TETRAHEDRON-ASYMMETRY
Artículo2006 Biocatalytic properties of Baeyer-Villiger monooxygenases in aqueous-organic media JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2006 Chemoenzymatic preparation of enantiopure isomers of 4-aminochroman-3-ol and 1-amino-1,2,3,4-tetrahydronaphthalen-2-ol EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2005 [Cp*Rh(bpy)(H2O)](2+) as a coenzyme substitute in enzymatic oxidations catalyzed by Baeyer-Villiger monooxygenases CHEMICAL COMMUNICATIONS
Artículo2005 Enzymatic Baeyer-Villiger oxidation of bicyclic diketones ADVANCED SYNTHESIS & CATALYSIS
Ponencia2005 Exploring the biocatalytic potential of the novel thermostable Baeyer-Villiger monooxygenase: Phenylacetone monooxygenase JOURNAL OF BIOTECHNOLOGY
Artículo2005 Oxidations catalyzed by phenylacetone monooxygenase from Thermobifida fusca TETRAHEDRON-ASYMMETRY
Artículo2005 Theoretical studies of oxygen atom transfer from flavin to electron-rich substrates JOURNAL OF MOLECULAR STRUCTURE
Artículo2004 Enzymatic acylation reactions on omega-hydroxycyanohydrins TETRAHEDRON
Artículo2004 Resolution of free and N-protected 3-aminocyclohexanols via lipase-catalyzed enantioselective acylation in organic media TETRAHEDRON-ASYMMETRY
Artículo2003 Anhydrides as acylating agents in the enzymatic resolution of an intermediate of (-)-paroxetine JOURNAL OF ORGANIC CHEMISTRY
Artículo2003 Enzymatic alkoxycarbonylation reactions on the intermediate in the synthesis of (-)-paroxetine, trans-N-benzyloxycarbonyl-4-(4¿-fluorophenyl)-3-hydroxymethylpiperidin TETRAHEDRON-ASYMMETRY
Artículo2002 (R)-Oxynitrilase-catalyzed transformation of ¿-hydroxyalakanals JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Artículo2001 Enzymatic resolution of trans-4-(4¿-fluorophenyl)-3-hydroxymethylpiperidines, key intermediates in the synthesis of (-)-Paroxetine JOURNAL OF ORGANIC CHEMISTRY
Biotransformaciones en la síntesis y resolución de compuestos de interés farmacéutico (2003)
Dirigida por: Vicente Miguel Gotor Santamaría, María del Rosario Brieva Collado
Tesis dirigidas/tutorizadas:2
Fecha lectura Título Rol
19/03/2012 Aplicación de flavoenzimas en síntesis orgánica Director/a
21/05/2010 Empleo de nuevas baeyer-villiger monooxigenasas como biocatalizadores en la síntesis de compuestos oxigenados ópticamente activos Director/a

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
30/12/2016 31/12/2020 Investigador/a Desarrollo y Diversificación de Sistemas Catalíticos Innovadores. Aplicaciones en Catálisis Asimétrica (CTQ2016-76908-C2-2-P) Ministerio de Economía y Competitividad (Nacional)
01/02/2020 30/04/2022 Investigador/a Diseño Racional de Catalizadores Quirales Avanzados Orientados a Aplicaciones en Catálisis Enantioselectiva (US-1262867) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)
01/01/2020 31/01/2023 Investigador/a Diseño racional de catalizadores quirales avanzados orientado a aplicaciones en catálisis enantioselectiva (P18-FR-644) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)
01/03/2022 28/02/2027 Responsable Design of Catalytic Processes with Deep Eutectic Solvents - DECADES (GRANT AGREEMENT 101072731) Comisión Europea (Europeo)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2024 31/03/2024 Responsable Síntesis de compuestos aromáticos en un reactor de flujo (5002/2044) Destilaciones Bordas Chinchurreta, S.A. (Desconocido)

Patentes

Nº Solicitud Fecha Solicitud Fecha Concesión Nombre
P200101648 13/07/2001 13/09/2004 Precursores opticamente puros de paroxetina