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Fernando Calvo Baltanas

Profesor Contratado Doctor
fcalvo@us.es
Área de conocimiento: Fisiología
Departamento: Fisiología Médica y Biofísica
Grupo: Sin Grupo
Instituto de Inv.: IBIS
Tipo Año Título Fuente
Editorial2023 Advances in molecular research of oncogenes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2023 Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma NATURE COMMUNICATIONS
Artículo2022 Critical requirement of SOS1 for development of BCR/ABL-driven chronic myelogenous leukemia CANCERS
Artículo2021 Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis ONCOGENE
Artículo2021 Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis CANCERS
Revisión2021 SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Revisión2021 The Childhood-Onset Neurodegeneration with Cerebellar Atrophy (CONDCA) Disease Caused by AGTPBP1 Gene Mutations: The Purkinje Cell Degeneration Mouse as an Animal Model for the Study of this Human Disease Biomedicines
Resumen congreso2020 Improved Delivery in a New Clinical Trial of AAV2-BDNF Gene Therapy for Alzheimer's Disease MOLECULAR THERAPY
Artículo2020 Postmortem Analysis in a Clinical Trial of AAV2-NGF Gene Therapy for Alzheimer's Disease Identifies a Need for Improved Vector Delivery HUMAN GENE THERAPY
Revisión2020 SOS GEFs in health and disease BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Artículo2019 Frontline Science: TNF-alpha and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-gamma, and neutrophil proinflammatory responses Journal of leukocyte biology
Artículo2019 Nucleolin reorganization and nucleolar stress in Purkinje cells of mutant PCD mice NEUROBIOLOGY OF DISEASE
Artículo2018 Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis MOLECULAR AND CELLULAR BIOLOGY
Artículo2018 Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis LEUKEMIA
Resumen congreso2016 Loss of viability correlates with altered organ homeostasis in the GI tract of adult, Sos1/2-depleted mice EUROPEAN JOURNAL OF CANCER
Artículo2016 Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs ONCOGENE
Resumen congreso2016 Sos1 disruption increases mitochondrial oxidative stress in primary MEFs EUROPEAN JOURNAL OF CANCER
Artículo2015 Nuclear signs of pre-neurodegeneration NEURONAL CELL DEATH: METHODS AND PROTOCOLS
Artículo2013 Differential glial activation during the degeneration of Purkinje cells and mitral cells in the PCD mutant mice GLIA
Artículo2013 Functional Redundancy of Sos1 and Sos2 for Lymphopoiesis and Organismal Homeostasis and Survival MOLECULAR AND CELLULAR BIOLOGY
Artículo2013 The Olfactory System as a Puzzle: Playing With Its Pieces ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
Artículo2012 CHANGES IN THE SEROTONERGIC SYSTEM AND IN BRAIN-DERIVED NEUROTROPHIC FACTOR DISTRIBUTION IN THE MAIN OLFACTORY BULB OF pcd MICE BEFORE AND AFTER MITRAL CELL LOSS NEUROSCIENCE
Resumen congreso2012 Effect of son of sevenless proteins depletion in mouse embryonic fibroblasts EUROPEAN JOURNAL OF CANCER
Artículo2011 Bone Marrow Contributes Simultaneously to Different Neural Types in the Central Nervous System Through Different Mechanisms of Plasticity Cell Transplantation
Artículo2011 LONG-LASTING CHANGES IN THE ANATOMY OF THE OLFACTORY BULB AFTER IONIZING IRRADIATION AND BONE MARROW TRANSPLANTATION NEUROSCIENCE
Artículo2011 Nucleolar Disruption and Cajal Body Disassembly are Nuclear Hallmarks of DNA Damage-Induced Neurodegeneration in Purkinje Cells Brain Pathology
Artículo2011 Purkinje Cell Degeneration in pcd Mice Reveals Large Scale Chromatin Reorganization and Gene Silencing Linked to Defective DNA Repair JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2011 Types of Cholecystokinin-Containing Periglomerular Cells in the Mouse Olfactory Bulb JOURNAL OF NEUROSCIENCE RESEARCH
Artículo2009 Albumin attenuates DNA damage in primary-cultured neurons Neuroscience Letters
Artículo2009 Chemical Characterization of Pax6-Immunoreactive Periglomerular Neurons in the Mouse Olfactory Bulb CELLULAR AND MOLECULAR NEUROBIOLOGY
Artículo2009 Sexual dimorphic stages affect both proliferation and serotonergic innervation in the adult rostral migratory stream EXPERIMENTAL NEUROLOGY
Artículo2008 Zincergic innervation from the anterior olfactory nucleus to the olfactory bulb displays plastic responses after mitral cell loss JOURNAL OF CHEMICAL NEUROANATOMY
Revisión2007 Chemical heterogeneity of the periglomerular neurons in the olfactory bulb. A review European Journal Of Anatomy
Artículo2007 Chemical organization of the macaque monkey olfactory bulb: III. Distribution of cholinergic markers JOURNAL OF COMPARATIVE NEUROLOGY
Capítulo2006 Plasticidad en el sistema olfatorio adulto La olfacción en España

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/09/2023 31/08/2026 Responsable La ruta RAS/MAPK como nueva diana terapeutica para el neuroblastoma recurrente (PID2022-136409OB-I00) Ministerio de Ciencia e Innovación (Nacional)
01/09/2023 31/08/2025 Responsable Inhibición de la ruta de señalización RAS/MAPK como opción terapéutica en el neuroblastoma recurrente y resistente a terapia (CNS2022-135292) Ministerio de Ciencia e Innovación (Nacional)
01/01/2023 31/12/2024 Responsable Inhibición farmacológica de la ruta de señalización RAS/MAPK para el tratamiento del neuroblastoma recurrente y resistente a las terapias actuales (GETHI2022) Asociación Inés de Pablo Llorens (Autonómico)
El investigador no tiene ningún resultado de investigación asociado