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María Álvarez de Sotomayor Paz

Profesora Titular de Universidad
aldesoto@us.es
Área de conocimiento: Farmacología
Departamento: Farmacología
Grupo: FARMACOLOGÍA CARDIOVASCULAR - CTS-178 (Universidad de Sevilla)
Prog. doctorado: Programa de Doctorado en Farmacia (RD. 99/2011)
Tipo Año Título Fuente
Resumen congreso2023 ECOE en las Prácticas Tuteladas del Grado en Farmacia de la Universidad de Sevilla XVI Congreso SEFIG ( 16. 2023. Madrid): Libro de comunicaciones
Artículo2023 Effects of dietary oleacein treatment on endothelial dysfunction and lupus nephritis in Balb/C pristane-induced mice. ANTIOXIDANTS
Artículo2023 Impact of Frailty on Outcomes of First-Line Pembrolizumab Monotherapy in a Real-World Population with Advanced Non-Small Cell Lung Cancer Biology
Artículo2023 Oleocanthal Supplemented Diet Improves Renal Damage And Endothelial Dysfunction In Pristane-Induced Systemic Lupus Erythematosus In Mice FOOD RESEARCH INTERNATIONAL
Revisión2023 Perfluorohexyloctane in dry eye disease: A systematic review of its efficacy and safety as a novel therapeutic agent Ocular Surface
Artículo2023 Programa de Formación en Innovación educativa para el profesorado novel de la Facultad de Farmacia (RADIF) RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2022 Alfabetización en salud y COVID-19 en mayores: aproximación desde la Farmacia Comunitaria Pharmaceutical Care España
Artículo2022 Health literacy and COVID-19 in the elderly: approach from the community pharmacy Pharmaceutical Care España
Artículo2021 ¿Reducen las estatinas el riesgo de glaucoma? revisión de las evidencias ARS PHARMACEUTICA
Artículo2020 Estatinas y riesgo de diabetes tipo 2: resumen de las evidencias clínicas y factores que podrían favorecer la incidencia RESCIFAR Revista Española de Ciencias Farmacéuticas
Capítulo2020 Hematuria anemizante en paciente con doble anticoagulación oral para la fibrilación auricular Casos prácticos de farmacoterapia para farmacéuticos
Capítulo2020 Implementación de rúbricas para la evaluación de actividades prácticas en la facultad de farmacia de la universidad de sevilla Evaluación e innovación en educación superior e investigación
Capítulo2020 Paciente con hepatitis C y comorbilidades Casos prácticos de farmacoterapia para farmacéuticos
Artículo2020 Pomace olive oil concentrated in triterpenic acids restores vascular function, glucose tolerance and obesity progression in mice NUTRIENTS
Resumen congreso2019 Concurso de casos prácticos para el alumnado de la Facultad de Farmacia de Sevilla Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Artículo2019 Determinación del valor umbral del índice de complejidad de la farmacoterapia para predecir polifarmacia en pacientes VIH+ Revista Española de Quimioterapia
Resumen congreso2019 Implementación de supuestos prácticos y una rúbrica de evaluación para su resolución en las prácticas tuteladas del grado en farmacia Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Ponencia2019 La gestión por procesos en los laboratorios de docencia de la facultad de farmacia de la Universidad de Sevilla Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Ponencia2019 Pomace Olive Oil Enriched In Oleanolic Acid Improves Diet-Induced Obesity And Exerts Protective Effects In Vascular Dysfunction And Metabolic Parameters ATHEROSCLEROSIS
Artículo2019 Prevalence of Polypharmacy and Association to Pharmacotherapy Complexity in Older HIV-Positive Patients. The Sevihlla Study International Journal of Aging Research
Artículo2018 Identification of the Medication Regimen Complexity Index as an Associated Factor of Nonadherence to Antiretroviral Treatment in HIV Positive Patients ANNALS OF PHARMACOTHERAPY
Revisión2018 The challenge of aging and pharmacoterapeutic complexity in the HIV + patient FARMACIA HOSPITALARIA
Artículo2017 Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production FOOD & FUNCTION
Revisión2017 Contribution of ferulic acid, gamma-oryzanol and tocotrienols to the cardiometabolic protective effects of rice bran JOURNAL OF FUNCTIONAL FOODS
Artículo2017 Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2017 Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE-/- mice EUROPEAN JOURNAL OF NUTRITION
Ponencia2017 Pomace olive oil enriched in oleanolic acid restores vascular dysfunction and metabolic parameters in mice fed a high fat diet BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2017 Rice bran enzymatic extract reduces atherosclerotic plaque development and steatosis in high-fat fed ApoE-/- mice NUTRITION
Artículo2016 Analysis of the implementation of GESIDA quality indicators in the HIV+ cohort PSITAR OFIL Revista
Artículo2016 Atherosclerosis-related inflammation and oxidative stress are improved by rice bran enzymatic extract JOURNAL OF FUNCTIONAL FOODS
Artículo2016 Development of a taxonomy for pharmaceutical interventions in HIV+ patients based on the CMO model FARMACIA HOSPITALARIA
Artículo2016 Diet supplementation with rice bran enzymatic extract restores endothelial impairment and wall remodelling of ApoE(-/-) mice microvessels ATHEROSCLEROSIS
Artículo2016 Increased oxidative stress and impaired mitochondrial biogenesis and dynamics are improved by rice bran enzymatic extract diet supplementation ATHEROSCLEROSIS
Artículo2015 Phenolic content of extra virgin olive oil is essential to restore endothelial dysfunction but not to prevent vascular inflammation in atherosclerotic lesions of Apo E deficient mice JOURNAL OF FUNCTIONAL FOODS
Ponencia2015 Rice bran enzymatic extract diet supplementation reduces oxidative stress and inflammation associated to atherosclerosis disease in apoe(-/-) mice BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2015 Rice bran enzymatic extract prevents atherosclerotic plaque development through its hipolipidemic and antiinflamatory effects ATHEROSCLEROSIS
Ponencia2015 Rice bran enzymatic extract prevents endothelial dysfunction and restores structural, mechanical and myogenic alterations of resistance arteries in apoe(-/-) mice BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2015 Structural, mechanical and myogenic properties of small mesenteric arteries from ApoE KO mice: Characterization and effects of virgin olive oil diets ATHEROSCLEROSIS
Ponencia2014 Oleaster, a new virgin olive oil protects against atherosclerotic process in apoe ko mice by reducing inflammatory mediators and superoxide production ATHEROSCLEROSIS
Ponencia2014 Rice bran enzymatic extract reduces atherosclerotic lesions in apo e (-/-) mice BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2014 Rice bran enzymatic extract reduces oxidative stress and restores mesenteric endothelium dependant dilatation in apo e (-/-) mice ATHEROSCLEROSIS
Ponencia2014 Virgin olive oil restores structural, myogenic and functional alterations of small mesenteric arteries from apoe ko mice ATHEROSCLEROSIS
Ponencia2013 A rice bran supplemented-diet restored the edhf-contribution to the vascular function of resistance arteries from obese zucker rats BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2013 Antioxidant protection of grape pomace enzymatic extract and its major polyphenols upon nadph oxidase activation and superoxide dismutase inhibition BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2013 Grape pomace enzymatic extract restores vascular dysfunction evoked by endothelin-1 and DETCA via NADPH oxidase downregulation and SOD activation JOURNAL OF FUNCTIONAL FOODS
Ponencia2013 Oleaster (r) improves endothelial dysfunction associated to atherosclerosis by reducing inflammatory mediators and superoxide anion production BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2013 Protección antioxidante de un extracto enzimático de orujo de la uva y sus polifenoles mayoritarios sobre la activación de NADPH oxidasa y la inhibición de superóxido dismutasa Actualidad en Farmacología y Terapéutica
Artículo2013 Rice bran enzymatic extract restores endothelial function and vascular contractility in obese rats, by reducing vascular inflammation and oxidative stress JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2013 Water-soluble rice bran enzymatic extract attenuates dyslipidemia, hypertension and insulin resistance in obese Zucker rats EUROPEAN JOURNAL OF NUTRITION
Artículo2012 Endothelium-dependent vasodilator and antioxidant properties of a novel enzymatic extract of grape pomace from wine industrial waste FOOD CHEMISTRY
Artículo2012 Propionyl-L-carnitine Corrects Metabolic and Cardiovascular Alterations in Diet-Induced Obese Mice and Improves Liver Respiratory Chain Activity PLOS ONE
Ponencia2011 Análisis, desarrollo e implantación de un sistema web de consulta yreserva on-line de grupos de prácticas para el alumnado VIII Foro sobre Evaluación de la Calidad de la Investigación y de la Educación Superior: libro de capítulos
Revisión2011 Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders VASCULAR HEALTH AND RISK MANAGEMENT
Póster2011 Endothelium-dependent vasodilating and antioxidant properties of a novel enzymatic extract of grape pomace from wine industrial wast BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2011 Mechanisms implicated in the effects of propionyl-l-carnitine on the obesity-related insulin resistance state BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Revisión2011 Pharmacological effects and clinical applications of propionyl-L-carnitine NUTRITION REVIEWS
Ponencia2011 Treatment with a novel rice bran enzymatic extract improves cardiometabolic risk factors in obese zucker rats BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2011 Vascular contribution of adrenomedullin to microcirculatory improvement in experimental colitis EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2010 Chronic Treatment With the Cannabinoid 1 Antagonist Rimonabant Altered Vasoactive Cyclo-oxygenase-Derived Products on Arteries From Obese Zucker Rats JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Revisión2010 Endothelial dysfunction and aging: An update AGEING RESEARCH REVIEWS
Ponencia2010 Propionyl-1-carnitine prevent metabolic and cardiovascular alterations in a model of diet-induced obesity FUNDAMENTAL & CLINICAL PHARMACOLOGY
Ponencia2010 Vasorelaxant effect induced by a grape pomace extract obtained by a novel enzymatic process HYPERTENSION
Artículo2009 Effects of Chronic Treatment With the CB1 Antagonist, Rimonabant on the Blood Pressure, and Vascular Reactivity of Obese Zucker Rats OBESITY
Artículo2009 Effects of pomace olive oil-enriched diets on endothelial function of small mesenteric arteries from spontaneously hypertensive rats BRITISH JOURNAL OF NUTRITION
Revisión2009 Mechanism involved in aged-related endothelial dysfuntion MEDICINA CLINICA
Artículo2009 Oral supplementation of propionyl-L-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats BRITISH JOURNAL OF NUTRITION
Artículo2009 Time-Dependent Protective Efficacy of Trolox (Vitamin E Analog) Against Microcystin-Induced Toxicity in Tilapia (Oreochromis niloticus) Environmental Toxicology
Artículo2008 Cedrelopsis grevei improves endothelial vasodilatation in aged rats through an increase of NO participation JOURNAL OF ETHNOPHARMACOLOGY
Artículo2008 Effects of HMG-CoA reductase inhibition by simvastatin on vascular dysfunction induced by lipopolysaccharide in rats PHARMACOLOGY
Ponencia2008 Effects of long-term propionyl-l-carnitine treatment on metabolic syndrome developed by obese zucker rats METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Ponencia2008 Rimonabant modifies participation of no and cox products on vascular function of obese zucker rats METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Artículo2007 Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR JOURNAL OF VASCULAR RESEARCH
Artículo2007 Fenofibrate improves age-related endothelial dysfunction in rat resistance arteries ATHEROSCLEROSIS
Artículo2007 L-carnitine and its propionate: Improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms FREE RADICAL RESEARCH
Artículo2007 Pomace olive oil improves endothelial function in spontaneously hypertensive rats by increasing endothelial nitric oxide synthase expression AMERICAN JOURNAL OF HYPERTENSION
Ponencia2006 Activity changes of betaadrenoceptors after abboplegisol induced tracheoplegia, in rat tracheal grafts FASEB JOURNAL
Artículo2005 Improvement of age-related endothelial dysfunction by simvastatin: effect on NO and COX pathways BRITISH JOURNAL OF PHARMACOLOGY
Artículo2005 L-carnitine and propionyl-L-camitine improve endothelial dysfunction in spontaneously hypertensive rats: Different participation of NO and COX-products LIFE SCIENCES
Artículo2005 Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin PHARMACOLOGY
Artículo2004 Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats BRITISH JOURNAL OF NUTRITION
Ponencia2004 Pleiotropic effects of sinivastin on endothelial dysfunction from aged rats: Role of NO and cyclo-oxygenase products ATHEROSCLEROSIS SUPPLEMENTS
Ponencia2004 Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin FUNDAMENTAL & CLINICAL PHARMACOLOGY
Ponencia2004 Treatment with the PPAR ALPHA agonist, fenofibrate improves age-related endothelial dysfunction in resistance arteries ATHEROSCLEROSIS SUPPLEMENTS
Artículo2003 Effects of simastatin on endothelial function after chronic inhibition of nitric oxide synthase by L-NAME JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Artículo2003 Hypolipidemic and hypocholesterolemic effect of argan oil (Argania spinosa L.) in Meriones shawi rats JOURNAL OF ETHNOPHARMACOLOGY
Artículo2003 Preservation of vascular contraction during ageing: dual effect on calcium handling and sensitization BRITISH JOURNAL OF PHARMACOLOGY
Artículo2002 Endothelium-dependent vasorelaxation induced by L-carnitine in isolated aorta from normotensive and hypertensive rats JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo2002 Simvastatin improves endothelial function in spontaneously hypertensive rats through a superoxide dismutase mediated antioxidant effect JOURNAL OF HYPERTENSION
Artículo2001 A pharmacological study of Cecropia obtusifolia Bertol aqueous extract JOURNAL OF ETHNOPHARMACOLOGY
Artículo2001 Effect of simvastatin on vascular smooth muscle responsiveness: involvement of Ca2+ homeostasis EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2001 Simvastatin and Ca2+ signaling in endothelial cells: Involvement of Rho protein BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Artículo2000 Characterization of endothelial factors involved in the vasodilatory effect of simvastatin in aorta and small mesenteric artery of the rat BRITISH JOURNAL OF PHARMACOLOGY
Artículo2000 Endothelium modulates contractile response to simvastatin in rat aorta ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Artículo2000 Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids BRITISH JOURNAL OF PHARMACOLOGY
Ponencia1999 Effect of aging on the endothelium-dependent relaxation induced by acetylcholine in mesenteric resistance arteries of the rat ENDOTHELIUM-DEPENDENT HYPERPOLARIZATIONS
Artículo1999 Effects of chronic treatment with simvastatin on endothelial dysfunction in spontaneously hypertensive rats JOURNAL OF HYPERTENSION
Artículo1999 Interés terapéutico de las estatinas en el tratamiento de la aterosclerosis ARS PHARMACEUTICA
Ponencia1997 Effect of ageing on endothelial function and vascular reactivity in rat conductance and resistance arteries BRITISH JOURNAL OF PHARMACOLOGY
Artículo1997 Uterine relaxant effect of zolpidem: A comparison with other smooth muscle relaxants ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2018 30/06/2021 Investigador/a Secoiridoides del olivo como nuevos nutracéuticos moduladores epigenéticos de la respuesta inmunoinflamatoria (AGL2017-89342-P) Ministerio de Economía y Competitividad (Nacional)
21/06/2010 31/12/2013 Investigador/a Investigación y desarrollo de nuevas posibilidades de aplicaciones terapéuticas en el aceite de oliva (IPT-060000-2010-28) Ministerio de Ciencia e Innovación (Nacional)
01/03/2010 29/02/2012 Investigador/a Obtención y escalado a planta piloto de extractos enzimáticos procedentes de co-productos agroindustriales: caracterización de las propiedades funcionales a nivel cardiovascular y síndrome metabólico (TRA2009_0263_02) Ministerio de Ciencia e Innovación (Nacional)
01/01/2010 31/12/2012 Investigador/a Transferencia y bioacumulacion de cilindrospermopsina en pescados de consumo público a escala de laboratorio, y evaluación de su toxicidad (AGL2009-10026) Ministerio de Ciencia e Innovación (Nacional)
01/01/2010 31/12/2012 Investigador/a Caracterización de las propiedades funcionales a nivel cardiovascular y del síndrome metabólico de un extracto enzimático del salvado de arroz (AGL2009-11559) Ministerio de Ciencia e Innovación (Nacional)
01/10/2006 30/09/2009 Investigador/a Contaminación de pescados de consumo público con microcistinas: métodos in vivo in vitro de evaluación de toxicidad y prevención de riesgos tóxicos derivados (AGL2006-06523) Ministerio de Educación y Ciencia (Nacional)
El investigador no tiene ningún resultado de investigación asociado