Artículo | 2024 |
Assessing the Potential of 1,2,3-Triazole-Dihydropyrimidinone Hybrids Against Cholinesterases: In Silico, In Vitro, and In Vivo Studies
|
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Artículo | 2024 |
Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2024 |
Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases
|
BIOORGANIC CHEMISTRY |
Artículo | 2024 |
Enhanced Recognition Memory through Dual Modulation of Brain Carbonic Anhydrases and Cholinesterases
|
JOURNAL OF MEDICINAL CHEMISTRY |
Corrección | 2024 |
Erratum: Correction: A Straightforward Access to New Families of Lipophilic Polyphenols by Using Lipolytic Bacteria (PloS one (2016) 11 11 DOI: 10.1371/journal.pone.0166561)
|
PLOS ONE |
Artículo | 2024 |
N-Alkyl Isofagomine Lactams: Synthesis, Glycosidase Inhibition, and Antimicrobial Assessments
|
SYNTHESIS-STUTTGART |
Artículo | 2024 |
Novel Coumarin-Steroid/Terpenoid Hybrids: In Vitro and In Silico Anticancer Studies
|
Chemistry & Biodiversity |
Revisión | 2024 |
Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2023 |
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration
|
ANTIOXIDANTS |
Artículo | 2023 |
Biotinylated selenocyanates: potent and selective cytostatic agents
|
BIOORGANIC CHEMISTRY |
Artículo | 2023 |
Conformationally restricted glycoconjugates derived from arylsulfonamides and coumarins: new families of tumour-associated carbonic anhydrase inhibitors
|
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Artículo | 2023 |
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies
|
BIOORGANIC & MEDICINAL CHEMISTRY |
Artículo | 2023 |
Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers.
|
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
Artículo | 2023 |
N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer's Disease
|
Results in Chemistry |
Artículo | 2023 |
Revisiting purine nucleoside cholinesterase inhibitors - An experimental glycon structure/activity relationship study.
|
MEDICINAL CHEMISTRY |
Artículo | 2022 |
2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases
|
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
Artículo | 2022 |
A gliclazide complex based on palladium towards Alzheimer's disease: promising protective activity against Aβ-induced toxicity in C. elegans
|
CHEMICAL COMMUNICATIONS |
Artículo | 2022 |
A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE).
|
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
Revisión | 2022 |
Butyrylcholinesterase inhibitors as potential anti-Alzheimer’s agents: an updated patent review (2018-present)
|
EXPERT OPINION ON THERAPEUTIC PATENTS |
Artículo | 2022 |
Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease
|
BIOORGANIC CHEMISTRY |
Artículo | 2022 |
Chemoselective Preparation of New Families of Phenolic-Organoselenium Hybrids-A Biological Assessment.
|
MOLECULES |
Artículo | 2022 |
Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease
|
BIOORGANIC & MEDICINAL CHEMISTRY |
Artículo | 2022 |
Functionalized d - And l - no -Pyrrolidines as Potent and Selective Glycosidase Inhibitors
|
SYNTHESIS-STUTTGART |
Revisión | 2022 |
Iridium-and palladium-based catalysts in the pharmaceutical industry
|
CATALYSTS |
Artículo | 2022 |
Squaramide-tethered sulfonamides and coumarins: synthesis, inhibition of tumor-associated CAs IX and XII and docking simulations
|
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Artículo | 2022 |
Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agents
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2022 |
Survey of new, small-molecule isatin-based oxindole hybrids as multi-targeted drugs for the treatment of Alzheimer’s disease
|
SYNTHESIS-STUTTGART |
Artículo | 2022 |
Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis
|
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
Artículo | 2021 |
Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
|
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
Revisión | 2021 |
Metal- and metalloid-based compounds to target and reverse cancer multidrug resistance
|
DRUG RESISTANCE UPDATES |
Artículo | 2021 |
Novel 1,2,3-triazole epicinchonas: transitioning from organocatalysis to biological activities
|
SYNTHETIC COMMUNICATIONS |
Artículo | 2021 |
Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors.
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2021 |
Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
|
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
Artículo | 2021 |
Ugi reaction synthesis of oxindole-lactam hybrids as selective butyrylcholinesterase inhibitors
|
ACS MEDICINAL CHEMISTRY LETTERS |
Artículo | 2020 |
1,4-Dideoxy-1,4-imino- d -arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α-Mannosidase Inhibitors
|
ACS OMEGA |
Revisión | 2020 |
Carbohydrates: Potential Sweet Tools against Cancer
|
CURRENT MEDICINAL CHEMISTRY |
Artículo | 2020 |
Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease
|
JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2020 |
Masked phenolic-selenium conjugates: Potent and selective antiproliferative agents overcoming p-gp resistance
|
PHARMACEUTICALS |
Artículo | 2020 |
N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study
|
BIOORGANIC CHEMISTRY |
Artículo | 2019 |
Bicyclic 1-Azafagomine Derivatives: Synthesis and Glycosidase Inhibitory Testing
|
SYNTHESIS-STUTTGART |
Artículo | 2019 |
Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and A beta(1-42)-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells
|
PHARMACEUTICALS |
Artículo | 2019 |
In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor
|
BIOORGANIC & MEDICINAL CHEMISTRY |
Artículo | 2019 |
Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Nota | 2019 |
Síntesis de nuevos selenoheterociclos derivados de carbohidratos
|
Revista Latinoamericana de Quimica |
Artículo | 2019 |
Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2018 |
Chalcogen-containing phenolics as antiproliferative agents
|
FUTURE MEDICINAL CHEMISTRY |
Artículo | 2018 |
Debates: An Useful Tool to Promote Students Deeper Thinking in Stem Disciplines
|
Proceedings (MDPI) |
Artículo | 2018 |
Synthesis of unprecedented steroidal Spiro heterocycles as potential antiproliferative drugs
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2017 |
New selenosteroids as antiproliferative agents
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2017 |
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2017 |
Selenoureas for anion binding as molecular logic gates
|
CHEMICAL COMMUNICATIONS |
Artículo | 2017 |
Sugar hydrazide imides: a new family of glycosidase inhibitors
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2017 |
Synthesis and antiproliferative activity of sulfa-Michael adducts and thiochromenes derived from carbohydrates
|
NEW JOURNAL OF CHEMISTRY |
Artículo | 2016 |
A Straightforward Access to New Families of Lipophilic Polyphenols by Using Lipolytic Bacteria
|
PLOS ONE |
Artículo | 2016 |
Design of chalcogen-containing norepinephrines: efficient GPx mimics and strong cytotoxic agents against HeLa cells
|
FUTURE MEDICINAL CHEMISTRY |
Capítulo | 2016 |
Green Chemical Synthesis and Click Reactions
|
Click Reactions in Organic Synthesis |
Artículo | 2016 |
Selenoureido-iminosugars: A new family of multitarget drugs
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2015 |
Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Artículo | 2015 |
Effects of dietary virgin olive oil polyphenols: hydroxytyrosyl acetate and 3, 4-dihydroxyphenylglycol on DSS-induced acute colitis in mice
|
JOURNAL OF NUTRITIONAL BIOCHEMISTRY |
Artículo | 2015 |
Phenolic thio- and selenosemicarbazones as multi-target drugs
|
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
Ponencia | 2015 |
Synthesis of fluorescent O-Coumarin glycosides as Potential drug delivery systems for MAO inhibitors
|
19TH INTERNATIONAL ELECTRONIC CONFERENCE ON SYNTHETIC ORGANIC CHEMISTRY |
Artículo | 2015 |
Synthesis of Organoselenium Derivatives of Biological Relevance
|
SELENIUM: CHEMISTRY, ANALYSIS, FUNCTION AND EFFECTS |
Artículo | 2014 |
An Alternative, Large-Scale Synthesis of 1,2:5,6-Di-O-isopropylidene-alpha-D-ribo-hex-3-ulofuranose
|
CARBOHYDRATE CHEMISTRY: PROVEN SYNTHETIC METHODS, VOL 2 |
Artículo | 2014 |
Eco-friendly preparation of 5-hydroxymethylfurfural from sucrose using ion-exchange resins
|
CHEMICAL ENGINEERING SCIENCE |
Artículo | 2014 |
Phenolic compounds and antioxidant capacity of virgin olive oil
|
FOOD CHEMISTRY |
Capítulo | 2014 |
Sulfur compounds as antioxidants: Beneficial effects on health
|
Advances in Chemistry Research |
Artículo | 2013 |
Enzyme inhibition by iminosugars: Analysis and insight into the glycosidase-iminosugar dependency of pH
|
BIOORGANIC & MEDICINAL CHEMISTRY |
Artículo | 2013 |
Synthesis and antioxidant activity of O-alkyl selenocarbamates, selenoureas and selenohydantoins
|
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES |
Artículo | 2012 |
A uronic acid analogue of isofagomine lactam as a nanomolar glucuronidase inhibitor
|
TETRAHEDRON LETTERS |
Artículo | 2012 |
Biological Properties of Hydroxytyrosol and Its Derivatives
|
OLIVE OIL - CONSTITUENTS, QUALITY, HEALTH PROPERTIES AND BIOCONVERSIONS |
Artículo | 2012 |
Glycosidase inhibitors: versatile tools in glycobiology
|
CARBOHYDRATE CHEMISTRY: CHEMICAL AND BIOLOGICAL APPROACHES, VOL 38 |
Artículo | 2012 |
Intramolecular cyclization of alkoxyaminosugars: access to novel glycosidase inhibitor families
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2012 |
L-Isofucoselenofagomine and derivatives: dual activities as antioxidants and as glycosidase inhibitors
|
TETRAHEDRON |
Artículo | 2012 |
Synthesis of conformationally-constrained thio(seleno)hydantoins and alpha-triazolyl lactones from D-arabinose as potential glycosidase inhibitors
|
TETRAHEDRON |
Artículo | 2012 |
Unprecedented spiro-annelated sugar isoureas, guanidines and amidines as new families of glycosidase inhibitors
|
RSC ADVANCES |
Artículo | 2011 |
Alkoxyamine-cyanoborane adducts: efficient cyanoborane transfer agents
|
CHEMICAL COMMUNICATIONS |
Artículo | 2011 |
An Isofagomine Analogue with an Amidine at the Pseudoanomeric Position
|
ORGANIC LETTERS |
Artículo | 2011 |
Classical Insecticides: Past, Present and Future
|
GREEN TRENDS IN INSECT CONTROL |
Artículo | 2010 |
A green procedure for the regio- and chemoselective hydrophosphonylation of unsaturated systems using CaO under solventless conditions
|
GREEN CHEMISTRY |
Artículo | 2010 |
Complexation of hydroxytyrosol with beta-cyclodextrins. An efficient photoprotection
|
TETRAHEDRON |
Artículo | 2010 |
Spiranic D-gluco-configured N-substituted thiohydantoins as potential enzymatic inhibitors
|
TETRAHEDRON |
Ponencia | 2010 |
Use of cooperative learning in stereochemistry teaching for organic compounds
|
3RD INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION (ICERI2010) |
Ponencia | 2010 |
Use of moodle online platform in learning nomenclature of organic compounds
|
3RD INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION (ICERI2010) |
Artículo | 2009 |
Difluoromethylenated polyhydroxylated pyrrolidines: facile synthesis, crystal structure and biological evaluation
|
FUTURE MEDICINAL CHEMISTRY |
Artículo | 2009 |
Synthesis and characterization of mercury(II)-sugar thioureas complexes
|
POLYHEDRON |
Artículo | 2009 |
Synthesis of sugar-derived isoselenocyanates, selenoureas, and selenazoles
|
TETRAHEDRON |
Artículo | 2009 |
Synthesis of the First Selenium-Containing Acyclic Nucleosides and Anomeric Spironucleosides from Carbohydrate Precursors
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2008 |
cis-Fused bicyclic sugar thiocarbamates. Reactivity towards amines
|
TETRAHEDRON |
Artículo | 2008 |
Effective synthesis of negatively charged cyclodextrins. Selective access to phosphate cyclodextrins
|
TETRAHEDRON |
Revisión | 2008 |
Hydroxytyrosol and derivatives: Isolation, synthesis, and biological properties
|
CURRENT ORGANIC CHEMISTRY |
Capítulo | 2008 |
Isofagomine, Noeuromycin and other 1-Azasugars, Iminosugar-Related Glycosidase Inhibitors
|
Iminosugars: From Synthesis to Therapeutic Applications |
Artículo | 2008 |
Taurine isothiocyanate: a versatile intermediate for the preparation of ureas, thioureas, and guanidines. Taurine-derived cyclodextrins
|
TETRAHEDRON LETTERS |
Artículo | 2007 |
Active site protonation of 1-azafagomine in glucosidases studied by solid-state NMR spectroscopy
|
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Artículo | 2007 |
Anorner-selective glycosidase inhibition by 2-N-alkylated 1-azafagomines
|
CHEMBIOCHEM |
Revisión | 2007 |
Click chemistry - What's in a name? Triazole synthesis and beyond
|
SYNTHESIS-STUTTGART |
Capítulo | 2007 |
Glycosidase Inhibitors: Structure, Activity, Synthesis, and Medical Relevance
|
Comprehensive Glycoscience: From Chemistry to Systems Biology |
Artículo | 2007 |
Heterocycles from Carbohydrate Isothiocyanates
|
HETEROCYCLES FROM CARBOHYDRATE PRECURSORS |
Artículo | 2007 |
New cup-shaped alpha-cyclodextrin derivatives and a study of their catalytic properties in oxidation reactions
|
TETRAHEDRON |
Artículo | 2007 |
Synthesis of Heterocycles from Glycosylamines and Glycosyl Azides
|
HETEROCYCLES FROM CARBOHYDRATE PRECURSORS |
Artículo | 2005 |
New synthetic approaches to sugar ureas. Access to ureido-beta-cyclodextrins
|
TETRAHEDRON |
Revisión | 2005 |
New trends in pest control: the search for greener insecticides
|
GREEN CHEMISTRY |
Artículo | 2004 |
Conformational effects on glycoside reactivity: Study of the high reactive conformer of glucose
|
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Artículo | 2004 |
Simple and efficient synthesis of O-unprotected glycosyl thiourea and isourea derivatives from glycosylamines
|
TETRAHEDRON |
Artículo | 2004 |
Synthesis of O-unprotected glycosyl selenoureas. A new access to bicyclic sugar isoureas
|
TETRAHEDRON LETTERS |
Artículo | 2003 |
A facile access to ureido sugars. Synthesis of urea-bridged beta-cyclodextrins
|
TETRAHEDRON LETTERS |
Artículo | 2003 |
Aziridines as a structural motif to conformational restriction of azasugars
|
ORGANIC & BIOMOLECULAR CHEMISTRY |
Artículo | 2003 |
Synthesis of furan 4 '-thio-C-nucleosides, their methylsulfonium and sulfoxide derivatives. Evaluation as glycosidase inhibitors
|
TETRAHEDRON |
Editorial | 2003 |
Titanium tetraisopropoxide
|
SYNLETT |
Artículo | 2002 |
Expeditious synthesis of cyclic isourea derivatives of beta-D-glucopyranosylamine
|
TETRAHEDRON LETTERS |
Artículo | 2001 |
A practical one-pot synthesis of O-unprotected glycosyl thioureas
|
TETRAHEDRON LETTERS |
Artículo | 1999 |
Stereoselective synthesis of imidazolidine, imidazoline and imidazole C- and N-pseudonucleosides
|
TETRAHEDRON-ASYMMETRY |