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QFC - Prisma - Unidad de Bibliometría

QUÍMICA FINA DE CARBOHIDRATOS - FQM-134 (QFC)

Tipo de colectivo: Grupo de investigación
Estado: Grupo definitivo
Ámbito: Andalucía
Instituciones: Universidad de Sevilla
Fecha de creación: 17/11/1988

Investiga en

Palabras clave
Líneas de investigación
Resumen
Nombre Rol
Fernández-Bolaños Guzmán, José María Investigador principal
Begines Aguilar, Paloma Miembro
López López, Oscar Miembro
Maya Castilla, Inés Miembro
Tipo Año Título Fuente
Artículo2024 Assessing the Potential of 1,2,3-Triazole-Dihydropyrimidinone Hybrids Against Cholinesterases: In Silico, In Vitro, and In Vivo Studies INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2024 Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2024 Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases BIOORGANIC CHEMISTRY
Artículo2024 Enhanced Recognition Memory through Dual Modulation of Brain Carbonic Anhydrases and Cholinesterases JOURNAL OF MEDICINAL CHEMISTRY
Corrección2024 Erratum: Correction: A Straightforward Access to New Families of Lipophilic Polyphenols by Using Lipolytic Bacteria (PloS one (2016) 11 11 DOI: 10.1371/journal.pone.0166561) PLOS ONE
Artículo2024 Identification of thienopyrimidine derivatives tethered with sulfonamide and other moieties as carbonic anhydrase inhibitors: Design, synthesis and anti-proliferative activity BIOORGANIC CHEMISTRY
Artículo2024 N-Alkyl Isofagomine Lactams: Synthesis, Glycosidase Inhibition, and Antimicrobial Assessments SYNTHESIS-STUTTGART
Artículo2024 Novel Coumarin-Steroid/Terpenoid Hybrids: In Vitro and In Silico Anticancer Studies Chemistry & Biodiversity
Artículo2024 Purine nucleosides as selective inhibitors of butyrylcholinesterase - a multidisciplinary study. ORGANIC & BIOMOLECULAR CHEMISTRY
Revisión2024 Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2024 Synthesis and investigation of selective human carbonic anhydrase IX, XII inhibitors using coumarins bearing a sulfonamide or biotin moiety CHEMICO-BIOLOGICAL INTERACTIONS
Artículo2023 A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration ANTIOXIDANTS
Artículo2023 Biotinylated selenocyanates: potent and selective cytostatic agents BIOORGANIC CHEMISTRY
Artículo2023 Conformationally restricted glycoconjugates derived from arylsulfonamides and coumarins: new families of tumour-associated carbonic anhydrase inhibitors INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2023 Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies BIOORGANIC & MEDICINAL CHEMISTRY
Artículo2023 Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Artículo2023 N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer's Disease Results in Chemistry
Artículo2023 Revisiting purine nucleoside cholinesterase inhibitors - An experimental glycon structure/activity relationship study. MEDICINAL CHEMISTRY
Artículo2022 2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Artículo2022 A gliclazide complex based on palladium towards Alzheimer's disease: promising protective activity against Aβ-induced toxicity in C. elegans CHEMICAL COMMUNICATIONS
Artículo2022 A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE). JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Revisión2022 Butyrylcholinesterase inhibitors as potential anti-Alzheimer’s agents: an updated patent review (2018-present) EXPERT OPINION ON THERAPEUTIC PATENTS
Artículo2022 Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease BIOORGANIC CHEMISTRY
Artículo2022 Chemoselective Preparation of New Families of Phenolic-Organoselenium Hybrids-A Biological Assessment. MOLECULES
Resumen congreso2022 Epigenetic interplay between H3K27ME3 and MIR-146A/B on the protective role of the nutraceutical oleocanthal in osteoarthritis OSTEOARTHRITIS AND CARTILAGE
Artículo2022 Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease BIOORGANIC & MEDICINAL CHEMISTRY
Artículo2022 Functionalized d - And l - no -Pyrrolidines as Potent and Selective Glycosidase Inhibitors SYNTHESIS-STUTTGART
Artículo2022 Identification of an acetyl esterase in the supernatant of the environmental strain Bacillus sp. HR21-6. BIOCHIMIE
Revisión2022 Iridium-and palladium-based catalysts in the pharmaceutical industry CATALYSTS
Artículo2022 Squaramide-tethered sulfonamides and coumarins: synthesis, inhibition of tumor-associated CAs IX and XII and docking simulations INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2022 Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agents EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2022 Survey of new, small-molecule isatin-based oxindole hybrids as multi-targeted drugs for the treatment of Alzheimer’s disease SYNTHESIS-STUTTGART
Artículo2022 Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Artículo2021 A new peracetylated oleuropein derivative ameliorates joint inflammation and destruction in a murine collagen-induced arthritis model via activation of the nrf-2/ho-1 antioxidant pathway and suppression of mapks and nf-κb activation NUTRIENTS
Artículo2021 Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Artículo2021 Encased gold nanoparticle synthesis as a probe for oleuropein self-assembled structure formation MATERIALS
Artículo2021 Inhibitory Effect of Olive Phenolic Compounds Isolated from Olive Oil By-Product on Melanosis of Shrimps ANTIOXIDANTS
Revisión2021 Metal- and metalloid-based compounds to target and reverse cancer multidrug resistance DRUG RESISTANCE UPDATES
Artículo2021 Novel 1,2,3-triazole epicinchonas: transitioning from organocatalysis to biological activities SYNTHETIC COMMUNICATIONS
Artículo2021 Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors. ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2021 Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Artículo2021 Ugi reaction synthesis of oxindole-lactam hybrids as selective butyrylcholinesterase inhibitors ACS MEDICINAL CHEMISTRY LETTERS
Artículo2020 1,4-Dideoxy-1,4-imino- d -arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α-Mannosidase Inhibitors ACS OMEGA
Revisión2020 Carbohydrates: Potential Sweet Tools against Cancer CURRENT MEDICINAL CHEMISTRY
Artículo2020 Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease JOURNAL OF MEDICINAL CHEMISTRY
Artículo2020 Masked phenolic-selenium conjugates: Potent and selective antiproliferative agents overcoming p-gp resistance PHARMACEUTICALS
Artículo2020 N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study BIOORGANIC CHEMISTRY
Artículo2020 Natural Deep Eutectic Solvent Extraction of Flavonoids of Scutellaria baicalensis as a Replacement for Conventional Organic Solvents MOLECULES
Artículo2020 Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function FOOD & FUNCTION
Artículo2020 Osteoarthritis treatment with a novel nutraceutical acetylated ligstroside aglycone, a chemically modified extra-virgin olive oil polyphenol Journal of Tissue Engineering
Ponencia2020 Transportable industrial plant for essence extraction Proceedings from the International Congress on Project Management and Engineering
Artículo2019 Bicyclic 1-Azafagomine Derivatives: Synthesis and Glycosidase Inhibitory Testing SYNTHESIS-STUTTGART
Artículo2019 Chemoenzymatic Synthesis and Radical Scavenging of Sulfated Hydroxytyrosol, Tyrosol, and Acetylated Derivatives JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2019 Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and A beta(1-42)-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells PHARMACEUTICALS
Artículo2019 Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2019 In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor BIOORGANIC & MEDICINAL CHEMISTRY
Resumen congreso2019 Oleocanthal modulates LPS-induced murine peritoneal macrophages activation via regulation of inflammasome and Nrf-2/HO-1 signaling pathways BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2019 Oleocanthal modulates LPS-induced murine peritoneal macrophages activation via regulation of inflammasome, Nrf-2/HO-1, and MAPKs signaling pathways JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2019 Olive secoiridoid oleuropein and its semisynthetic acetyl-derivatives reduce LPS-induced inflammatory response in murine peritoneal macrophages via JAK-STAT and MAPKs signaling pathways JOURNAL OF FUNCTIONAL FOODS
Artículo2019 Olive-Oil-Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF-κB Pathway MOLECULAR NUTRITION & FOOD RESEARCH
Otros2019 Selenium and sulphur derivatives of hydroxytyrosol: inhibition of lipid peroxidation in liver microsomes of vitamin E-deficient rats EUROPEAN JOURNAL OF NUTRITION
Artículo2019 Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Nota2019 Síntesis de nuevos selenoheterociclos derivados de carbohidratos Revista Latinoamericana de Quimica
Artículo2019 Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2018 Chalcogen-containing phenolics as antiproliferative agents FUTURE MEDICINAL CHEMISTRY
Artículo2018 Debates: An Useful Tool to Promote Students Deeper Thinking in Stem Disciplines Proceedings (MDPI)
Resumen congreso2018 Oleuropein and its new acylated derivatives reduce lps-induced inflammatory response in murine peritoneal macrophages BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2018 Peracetylated hydroxytyrosol, a new hydroxytyrosol derivate, attenuates LPS-induced inflammatory response in murine peritoneal macrophages via regulation of non-canonical inflammasome, Nrf2/HO1 and JAK/STAT signaling pathways JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2018 Synthesis of unprecedented steroidal Spiro heterocycles as potential antiproliferative drugs EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017 Dietary hydroxytyrosol and hydroxytyrosyl acetate supplementation prevent pristane-induced systemic lupus erythematous in mice JOURNAL OF FUNCTIONAL FOODS
Artículo2017 Extra-virgin olive oil phenols hydroxytyrosol and hydroxytyrosol acetate, down-regulate the production of mediators involved in joint erosion in human synovial cells JOURNAL OF FUNCTIONAL FOODS
Artículo2017 New selenosteroids as antiproliferative agents ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2017 New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017 Oleuropein down-regulated IL-1 beta-induced inflammation and oxidative stress in human synovial fibroblast cell line SW982 FOOD & FUNCTION
Corrección2017 Oleuropein down-regulated IL-1 beta-induced inflammation and oxidative stress in human synovial fibroblast cell line SW982 (vol 8, pg 1890, 2017) FOOD & FUNCTION
Resumen congreso2017 Oleuropein exhibited anti-inflammatory and anti-oxidant activities in il-1 beta-stimulated human synovial fibroblasts BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2017 Selenoureas for anion binding as molecular logic gates CHEMICAL COMMUNICATIONS
Artículo2017 Sugar hydrazide imides: a new family of glycosidase inhibitors ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2017 Synthesis and antiproliferative activity of sulfa-Michael adducts and thiochromenes derived from carbohydrates NEW JOURNAL OF CHEMISTRY
Artículo2016 A Straightforward Access to New Families of Lipophilic Polyphenols by Using Lipolytic Bacteria PLOS ONE
Artículo2016 Design of chalcogen-containing norepinephrines: efficient GPx mimics and strong cytotoxic agents against HeLa cells FUTURE MEDICINAL CHEMISTRY
Capítulo2016 Green Chemical Synthesis and Click Reactions Click Reactions in Organic Synthesis
Ponencia2016 Nuevos productos de interés biológico y tecnológico III Jornada de investigación y postgrado: Libro de Actas
Artículo2016 Selenoureido-iminosugars: A new family of multitarget drugs EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015 Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015 Effects of dietary virgin olive oil polyphenols: hydroxytyrosyl acetate and 3, 4-dihydroxyphenylglycol on DSS-induced acute colitis in mice JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2015 Isolation and Characterization of a Secoiridoid Derivative from Two-Phase Olive Waste (Alperujo) JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2015 Isolation and identification of minor secoiridoids and phenolic components from thermally treated olive oil by-products FOOD CHEMISTRY
Artículo2015 Naturally Occurring Hydroxytyrosol Derivatives: Hydroxytyrosyl Acetate and 3,4-Dihydroxyphenylglycol Modulate Inflammatory Response in Murine Peritoneal Macrophages. Potential Utility as New Dietary Supplements JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2015 Phenolic thio- and selenosemicarbazones as multi-target drugs EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015 Preventive effects of dietary hydroxytyrosol acetate, an extra virgin olive oil polyphenol in murine collagen-induced arthritis MOLECULAR NUTRITION & FOOD RESEARCH
Ponencia2015 Synthesis of fluorescent O-Coumarin glycosides as Potential drug delivery systems for MAO inhibitors 19TH INTERNATIONAL ELECTRONIC CONFERENCE ON SYNTHETIC ORGANIC CHEMISTRY
Artículo2015 Synthesis of Organoselenium Derivatives of Biological Relevance SELENIUM: CHEMISTRY, ANALYSIS, FUNCTION AND EFFECTS
Artículo2014 An Alternative, Large-Scale Synthesis of 1,2:5,6-Di-O-isopropylidene-alpha-D-ribo-hex-3-ulofuranose CARBOHYDRATE CHEMISTRY: PROVEN SYNTHETIC METHODS, VOL 2
Artículo2014 Anti-inflammatory and joint protective effects of extra-virgin olive-oil polyphenol extract in experimental arthritis JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2014 Eco-friendly preparation of 5-hydroxymethylfurfural from sucrose using ion-exchange resins CHEMICAL ENGINEERING SCIENCE
Ponencia2014 Extra virgen olive oil polyphenol derivatives downregulate lps-induced inflammatory response in murine peritoneal macrophages suppressing nf kappa b signalling pathway BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2014 Phenolic compounds and antioxidant capacity of virgin olive oil FOOD CHEMISTRY
Capítulo2014 Sulfur compounds as antioxidants: Beneficial effects on health Advances in Chemistry Research
Artículo2013 Enhanced chemopreventive activity of hydroxytyrosol on HL60 and HL60R cells by chemical conversion into thio derivatives EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Artículo2013 Enzyme inhibition by iminosugars: Analysis and insight into the glycosidase-iminosugar dependency of pH BIOORGANIC & MEDICINAL CHEMISTRY
Artículo2013 Synthesis and antioxidant activity of O-alkyl selenocarbamates, selenoureas and selenohydantoins EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Artículo2012 A uronic acid analogue of isofagomine lactam as a nanomolar glucuronidase inhibitor TETRAHEDRON LETTERS
Artículo2012 Biological Properties of Hydroxytyrosol and Its Derivatives OLIVE OIL - CONSTITUENTS, QUALITY, HEALTH PROPERTIES AND BIOCONVERSIONS
Artículo2012 Glycosidase inhibitors: versatile tools in glycobiology CARBOHYDRATE CHEMISTRY: CHEMICAL AND BIOLOGICAL APPROACHES, VOL 38
Artículo2012 Intramolecular cyclization of alkoxyaminosugars: access to novel glycosidase inhibitor families ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2012 L-Isofucoselenofagomine and derivatives: dual activities as antioxidants and as glycosidase inhibitors TETRAHEDRON
Artículo2012 Multivalent glycoconjugates in medicinal chemistry CARBOHYDRATE CHEMISTRY: CHEMICAL AND BIOLOGICAL APPROACHES, VOL 38
Artículo2012 New Olive-Pomace Oil Improved by Hydrothermal Pre-Treatments OLIVE OIL - CONSTITUENTS, QUALITY, HEALTH PROPERTIES AND BIOCONVERSIONS
Artículo2012 Synthesis of conformationally-constrained thio(seleno)hydantoins and alpha-triazolyl lactones from D-arabinose as potential glycosidase inhibitors TETRAHEDRON
Artículo2012 Unprecedented spiro-annelated sugar isoureas, guanidines and amidines as new families of glycosidase inhibitors RSC ADVANCES
Artículo2011 Alkoxyamine-cyanoborane adducts: efficient cyanoborane transfer agents CHEMICAL COMMUNICATIONS
Artículo2011 An Isofagomine Analogue with an Amidine at the Pseudoanomeric Position ORGANIC LETTERS
Artículo2011 Classical Insecticides: Past, Present and Future GREEN TRENDS IN INSECT CONTROL
Libro2011 Green Trends in Insect Control GREEN TRENDS IN INSECT CONTROL
Artículo2010 1-Alkoxyamino-2-nitroalkanes as Key Building Blocks for a Chemo- and Diastereoselective Synthesis of a New Type of Polyfunctionalized N-Alkoxypiperidine EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2010 A green procedure for the regio- and chemoselective hydrophosphonylation of unsaturated systems using CaO under solventless conditions GREEN CHEMISTRY
Artículo2010 Complexation of hydroxytyrosol with beta-cyclodextrins. An efficient photoprotection TETRAHEDRON
Artículo2010 Spiranic D-gluco-configured N-substituted thiohydantoins as potential enzymatic inhibitors TETRAHEDRON
Ponencia2010 Use of cooperative learning in stereochemistry teaching for organic compounds 3RD INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION (ICERI2010)
Ponencia2010 Use of moodle online platform in learning nomenclature of organic compounds 3RD INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION (ICERI2010)
Artículo2009 Difluoromethylenated polyhydroxylated pyrrolidines: facile synthesis, crystal structure and biological evaluation FUTURE MEDICINAL CHEMISTRY
Artículo2009 Synthesis and characterization of mercury(II)-sugar thioureas complexes POLYHEDRON
Artículo2009 Synthesis of sugar-derived isoselenocyanates, selenoureas, and selenazoles TETRAHEDRON
Artículo2009 Synthesis of the First Selenium-Containing Acyclic Nucleosides and Anomeric Spironucleosides from Carbohydrate Precursors EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2008 cis-Fused bicyclic sugar thiocarbamates. Reactivity towards amines TETRAHEDRON
Artículo2008 Effective synthesis of negatively charged cyclodextrins. Selective access to phosphate cyclodextrins TETRAHEDRON
Revisión2008 Hydroxytyrosol and derivatives: Isolation, synthesis, and biological properties CURRENT ORGANIC CHEMISTRY
Capítulo2008 Isofagomine, Noeuromycin and other 1-Azasugars, Iminosugar-Related Glycosidase Inhibitors Iminosugars: From Synthesis to Therapeutic Applications
Artículo2008 Taurine isothiocyanate: a versatile intermediate for the preparation of ureas, thioureas, and guanidines. Taurine-derived cyclodextrins TETRAHEDRON LETTERS
Artículo2007 Active site protonation of 1-azafagomine in glucosidases studied by solid-state NMR spectroscopy EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2007 Anorner-selective glycosidase inhibition by 2-N-alkylated 1-azafagomines CHEMBIOCHEM
Revisión2007 Click chemistry - What's in a name? Triazole synthesis and beyond SYNTHESIS-STUTTGART
Capítulo2007 Glycosidase Inhibitors: Structure, Activity, Synthesis, and Medical Relevance Comprehensive Glycoscience: From Chemistry to Systems Biology
Artículo2007 Heterocycles from Carbohydrate Isothiocyanates HETEROCYCLES FROM CARBOHYDRATE PRECURSORS
Artículo2007 New cup-shaped alpha-cyclodextrin derivatives and a study of their catalytic properties in oxidation reactions TETRAHEDRON
Revisión2007 SiO2-Supported CeCl3-7H(2)O-NaI Lewis acid promoter: Investigation into the Garcia Gonzalez reaction in solvent-free conditions JOURNAL OF ORGANIC CHEMISTRY
Artículo2007 Synthesis of Heterocycles from Glycosylamines and Glycosyl Azides HETEROCYCLES FROM CARBOHYDRATE PRECURSORS
Artículo2005 New synthetic approaches to sugar ureas. Access to ureido-beta-cyclodextrins TETRAHEDRON
Revisión2005 New trends in pest control: the search for greener insecticides GREEN CHEMISTRY
Artículo2004 Conformational effects on glycoside reactivity: Study of the high reactive conformer of glucose JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Artículo2004 Simple and efficient synthesis of O-unprotected glycosyl thiourea and isourea derivatives from glycosylamines TETRAHEDRON
Artículo2004 Synthesis of O-unprotected glycosyl selenoureas. A new access to bicyclic sugar isoureas TETRAHEDRON LETTERS
Artículo2003 A facile access to ureido sugars. Synthesis of urea-bridged beta-cyclodextrins TETRAHEDRON LETTERS
Artículo2003 Aziridines as a structural motif to conformational restriction of azasugars ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2003 Synthesis of 4-C-sulfoaminosugar derivatives: isomerization of 4-C-sulfogalactosamine to its gluco epimer TETRAHEDRON-ASYMMETRY
Artículo2003 Synthesis of furan 4 '-thio-C-nucleosides, their methylsulfonium and sulfoxide derivatives. Evaluation as glycosidase inhibitors TETRAHEDRON
Artículo2003 Synthesis of new C-sulfosugars and C-sulfoalditols: Amadori rearrangement of 6-C-sulfo-D-fucose TETRAHEDRON-ASYMMETRY
Editorial2003 Titanium tetraisopropoxide SYNLETT
Artículo2002 Expeditious synthesis of cyclic isourea derivatives of beta-D-glucopyranosylamine TETRAHEDRON LETTERS
Artículo2002 New N-alkylsulfonamides and alkyl sulfonates derived from 6-C-sulfosugars TETRAHEDRON
Artículo2002 Synthesis and biological evaluation of oligosaccharides related to the molecule signals in plant defence and the Rhizobium-legume symbiosis TETRAHEDRON
Artículo2002 Synthesis and evaluation of sulfonium analogues of isofucofagomine as glycosidase inhibitors Journal of the Chemical Society Perkin Transactions 1
Artículo2001 A practical one-pot synthesis of O-unprotected glycosyl thioureas TETRAHEDRON LETTERS
Ponencia2001 Evaluación ecotoxicológica en daphnia magna de tensioactivos derivados de la taurina Revista de Toxicología
Artículo2001 New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Artículo2001 Reactivity of polyhydroxyalkyl-heterocycles towards Lewis acids TETRAHEDRON-ASYMMETRY
Artículo2001 Solution and solid phase synthesis of hetarylene-carbopeptoids. A new type of peptidomimetics TETRAHEDRON LETTERS
Revisión2001 Sugar derivatives having sulfur in the ring ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL 57
Artículo2000 Glycosidase inhibition by phenylsulfinyl 2-deoxy-2-tetrachloro-phthalimido-beta-d-glucopyranoside and derivatives. Carbohydrate letters (Print)
Artículo1999 Stereoselective synthesis of imidazolidine, imidazoline and imidazole C- and N-pseudonucleosides TETRAHEDRON-ASYMMETRY
Artículo1999 Sugar isothiocyanate-sugar thiocarbamate equilibrium. synthesis of thiourea derivatives of methyl 2-amino-2-deoxy-a-d-glucopyranoside Carbohydrate letters (Print)
Artículo1999 Synthesis of 2-acylamino-2-deoxy-D-glucofuranoses and their transformation into hex-2-enofuranoses CARBOHYDRATE RESEARCH
Artículo1999 Synthesis of five-membered homothiosugars derived from L-erythrose and D-mannose TETRAHEDRON-ASYMMETRY
Artículo1998 Introduction of C-sulfonate groups into disaccharide derivatives SYNTHETIC COMMUNICATIONS
Artículo1998 Oxidation of polyhydroxyalkyl-heterocycles by cerium - (IV). A convenient route to pyrrole-2,5-dicarbaldehydes. TETRAHEDRON LETTERS
Artículo1997 4-thiopyranoside and 4-thiofuranoside derivatives of D-galactosamine CARBOHYDRATE RESEARCH
Artículo1996 Sulfoaminoglucitols: Synthesis of 2-amino-2,3 (and 2,6)-dideoxy-D-glucitol-3 (and 6)-sulfonic acids and X-ray crystal structure of the monohydrate of the 6-sulfo derivative CARBOHYDRATE RESEARCH
Artículo1995 Tensioactivos. XX. ω-Monoésteres grasos de ditioacetales de azúcares GRASAS Y ACEITES
Artículo1993 Cleavage and oligomerization of malondialdehyde TETRAHEDRON
Artículo1993 Synthesis and crystal-structure of methyl 2-amino-2,6-dideoxy-alpha-d-glucopyranoside-6-sulfonic acid CARBOHYDRATE RESEARCH
Artículo1992 Glucosylenamines as glycosyl acceptors - synthesis of gentiobiosylenamines CARBOHYDRATE RESEARCH
Nota1992 Synthesis and properties of 1,1,3,3-tetramethyl-2-(2,3,4,6-tetra-o-acetyl-alpha-d-glucopyranosyl)uronium triflate CARBOHYDRATE RESEARCH
Artículo1992 Synthesis of 1-aryl-(1,2-dideoxy-α-d-glucofurano)-[2,1-d]imidazolidine-2-selone s and the crystal structure of the 1-p-bromophenyl derivative CARBOHYDRATE RESEARCH
Artículo1992 Synthesis of the maillard reaction .2. Influence of malondialdehyde on the maillard degradation of amadori compounds CARBOHYDRATE RESEARCH
Artículo1991 A nuclear magnetic resonance spectroscopic and conformational study of eight pseudo-trehaloses (d-glucopyranosyl 5a-carba-d- and -l-glucopyranosides) CARBOHYDRATE RESEARCH
Artículo1991 Crystal and molecular structure of 1,3-dihydro-4-(3,4-O-isopropylidene-d-arabino-tetritol-1-yl)-3-methyl-1-p-tolyl-2H-imidazole-2- thione CARBOHYDRATE RESEARCH
Artículo1991 Reaction of 2-amino-2-deoxy-d-glucose with aryl and acyl isothiocyanates, and aryl isocyanates: structure of the intermediate products CARBOHYDRATE RESEARCH
Artículo1990 Cleavage and oligomerization of malondialdehyde under physiological conditions TETRAHEDRON LETTERS
Artículo1990 Imidazole surfactants .2. Synthesis of 1-alkyl-4-d-lyxo-tetrahydroxybutyl-1h-imidazoles GRASAS Y ACEITES
Artículo1990 Imidazole surfactants .3. Synthesis of 1-alkyl-1,3-dihydro-4-d-arabino-tetrahydroxybutyl-2h-imidazol-2-ones and 1-alkyl-4-d-threo-trihydroxypropyl-1h-imidazoles GRASAS Y ACEITES
Artículo1990 New synthesis of 1-alkyl(aryl)-2,3-dihydro-2-thioxo-1h-imidazole-4-carboxaldehydes JOURNAL OF ORGANIC CHEMISTRY
Artículo1990 Studies of the maillard reaction .1. Reaction of amino-sugars with malondialdehyde CARBOHYDRATE RESEARCH
Nota1990 Synthesis of (5s,8r,9r,10s)-8,9,10-trihydroxy-2-thioxo-1,6-dioxa-3-azaspiro[4.5]decane from 1-amino-1-deoxy-d-arabino-hexulose CARBOHYDRATE RESEARCH
Artículo1989 Synthesis and cyrstal and molecular structure of 4-(d-arabino-tetritol-1-yl)-4- imidazolin-2-ylideneammonium chloride CARBOHYDRATE RESEARCH
Artículo1989 The base-catalyzed rearrangement of dibromo alditols via epoxide migration ACTA CHEMICA SCANDINAVICA
Artículo1988 A 1H- and 13C-n.m.r. spectroscopic analysis of six pseudohexoses CARBOHYDRATE RESEARCH
Artículo1988 C-glycosides of imidazoles .11. Mono and ditosylation of 4-(alpha and beta-d-erythrofuranosyl)-1,3-dihydro-2h-imidazole-2-thiones ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1988 Surfactants .13. Syntheses of sodium 2-acylamino-2,6-dideoxy-d-glucopyranose-6-sulphonates CARBOHYDRATE RESEARCH
Artículo1988 Synthesis and conformational-analysis of methyl 3-o-[alpha-l( and d)-rhamnopyranosyl]maltoside derivatives - a branched trisaccharide with the central glucopyranose residue in the c-1(4) conformation CARBOHYDRATE RESEARCH
Artículo1988 Synthesis of 4-thio-c-nucleoside analogs by dehydration of 4-thiopolyhydroxyalkyl heterocycles CARBOHYDRATE RESEARCH
Artículo1987 Amidas y esteres grasos de aminoazucares V. 2-Acilamido (octanamido, lauramido)-2,6-didesoxi-6-yodo-D-glucosas. GRASAS Y ACEITES
Artículo1987 Garciagonzalez,Francisco 1902-1983 - Obituary ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY
Artículo1987 Synthesis of an optically-active alpha-methylene lactone starting from isosaccharinic acid ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY
Artículo1987 The substrate-specificity of the enzyme amyloglucosidase towards a pentadeoxy derivative of maltose GLYCOCONJUGATE JOURNAL
Artículo1986 Surfactans .11. Methyl-2-acylamido-2-deoxy-6-thio-alpha-d-glucopyranosides ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Nota1986 Synthesis of 2-amino-2,6-dideoxy-d-glucopyranose-6-sulfonic acid CARBOHYDRATE RESEARCH
Artículo1985 C-Glicósidos de Imidazoles. VIII. 3-Alquil (aril)-4.[2S Y 2R)-2,5-dihidro-2-furil]-1,3-dihidro-2H-imidazol-2-tionas Anales de la Real Sociedad Española de Química
Nota1985 Synthesis of 3-alkyl(aryl)-1-aryl-1,3-dihydro-2h-benzimidazole-2-thiones from 3-alkyl(aryl)-1-aryl-4-(alpha-d-erythrofuranosyl)-1,3-dihydro-2h-imidazole-2-thione and 3-alkyl(aryl)-1-aryl-4-(beta-d-erythrofuranosyl)-1,3-dihydro-2h-imidazole-2-thione CARBOHYDRATE RESEARCH
Artículo1985 Tensioactivos ix. 2-acilamido-2-desoxi-d-glucitoles. GRASAS Y ACEITES
Nota1985 Thiolglucimidazoles .16. Reaction of 1-deoxy-1-methylamino-d-lyxo-hexulose with phenyl isothiocyanate CARBOHYDRATE RESEARCH
Artículo1985 Tiolglucimidazoles. XIII. 3-n-alquil-1-aril-4,5(1,2-glucofurano)-inmidazolidina-2-tionas ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1983 C-glicósidos de imidazoles. VII. 3-Alquil(aril)-1-aril-4(α y β-D-eritrofuranosil)-1,3-dihidro-2H-imidazol-2-tionas ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1983 C-glycosides of imidazoles .7. 3(alkyl(aryl)-1-aryl-4-(alpha-d-erytrofuranosyl and beta-d-erytrofuranosyl)-1,3-dihydro-2h-imidazol-2-thiones ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Nota1983 Dithioacetals of sugars .17. Derivatives of 6-o-lauroyl(myristoil, palmitoyl)-d-galactose ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1982 Tensioactivos. IV. 2-0-acil-D-manitoles y 3-0-acil-D-manitoles ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Nota1972 Thiolglucimidazoles .9. Synthesis of 3-aryl(alkyl)-4-(d-arabino-tetrahydroxybutyl)imidazoline-2-thiones CARBOHYDRATE RESEARCH

Proyectos de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/09/2024 31/08/2027 Aproximaciones químicas frente al cáncer: nuevos compuestos citotóxicos y estrategias para su distribución selectiva (PID2023-147401OB-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 131.250,00 €
01/05/2024 30/04/2028 Innovative technologies to monitor and reduce Non Exhaust Emissions, particles and microplastics of VEhicles and pavements to improve air quality and human health. (LIFE23-ENV-ES-LIFE NEEVE) Comisión Europea (Europeo) 375.338,88 €
01/01/2024 30/06/2025 “OLE: Obtención de Productos ricos en Oleuropeina a partir de la hoja de Olivo” Grupo Operativo (Funcionamiento) (GOPG-SE-23-0003) Junta de Andalucía (Autonómico) 53.600,00 €
01/01/2022 31/05/2023 Secoiridoides del olivo en la terapia nutricional de la artritis reumatoide: implicaciones epigenéticas y metabolómicas (US-1380592) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 90.000,00 €
01/09/2021 28/02/2025 Sistemas químicos para la vectorización y liberación selectiva de nuevos inhibidores enzimáticos citotóxicos (PID2020-116460RB-I00) Ministerio de Ciencia e Innovación (Nacional) 84.700,00 €
30/12/2016 29/12/2019 Moléculas y Macromoléculas con Actividad Multidiana frente a enfermedades Degenerativas (CTQ2016-78703-P) Ministerio de Economía y Competitividad (Nacional) 76.230,00 €
26/03/2013 25/09/2016 Extremozimas Lipolíticas como Catalizadores Regioselectivos útiles en la Síntesis de Carbohidratos y Polifenoles Lipófilos (P11-CVI-7427) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 168.682,00 €
13/01/2009 31/12/2013 Optimización del Aislamiento de Polifenoles de la Aceituna. Complejación con Ciclodextrinas, Derivatización y Evaluación Como Agentes Antioxidantes. (P08-AGR-03751) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 243.123,68 €
01/01/2009 30/06/2013 Glicodiversificación de moléculas bioactivas (CTQ2008-02813) Ministerio de Educación y Ciencia (Nacional) 169.400,00 €
31/12/2005 31/12/2008 Derivados de carbohidratos como intermedios quirales clave en la síntesis de moléculas bioactivas (CTQ2005-01830) Ministerio de Educación y Ciencia (Nacional) 155.890,00 €
13/12/2004 13/12/2005 Derivados de carbohidratos que contienen nitrógeno, azufre y/o selenio como intermedios quirales clave en la síntesis de moléculas de interés biológico (CTQ2004-01178) Ministerio de Ciencia y Tecnología (Nacional) 6.900,00 €
28/12/2001 27/09/2005 Síntesis estereocontroladas de iminociclitoles, de N- y C-glicósidos y de (tio, seleno) carbomoil azúcares de interés biológico a partir de aminoazúcares y de sulfatos cíclicos (BQU2001-3740) Ministerio de Ciencia y Tecnología (Nacional) 117.167,28 €

Contratos

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
05/07/2024 04/01/2025 Investigación en técnicas verdes para la valorización industrial de distintas materias orgánicas (5186/0857) Azcatec Tecnología e Ingeniería S.L (Desconocido)
22/05/2023 21/11/2023 Diseño de una tecnología de deshidratación de alimentos mediante tecnología de microonda a vacío (DESHIDRATACION) (4877/0335) Azcatec Tecnología e Ingeniería S.L (Desconocido)
22/05/2022 21/11/2023 Extracción de compuestos fenólicos con disolventes eutécticos profundos naturales (NADES) (4878/0335) Azcatec Tecnología e Ingeniería S.L (Desconocido)
20/11/2020 15/01/2021 Análisis y cuantificación del contenido en Oleocantal de cinco muestras monovarietales de aceite de oliva virgen extra (3964/0335) COOP. AGRARIA OLEAND, S. COOP. AND. (Desconocido)
15/09/2017 14/10/2017 Determinación de Oleocantal y Oleaceína en Aceites de Oliva Virgen Extra (3145/0335) Ntra. Sra. de las Virtudes, S.C.A. (Desconocido)
20/04/2017 19/10/2017 Estudio sobre la influencia del tiempo y la temperatura en el contenido de polifenoles secoiridoides en AOVE de cosecha temprana Lote: YV0005 (3030/0335) Aceite Yoverde, S.L. (Desconocido)
26/10/2016 31/12/2019 Formulación de cera de limpieza rápida (2909/0857) LIPASAM (Desconocido)
15/03/2016 14/05/2016 Determinación de Oleocantal y Oleacaína en Aceites de Oliva Vírgen Extra (2750/0335) Ntra. Sra. de las Virtudes, S.C.A. (Desconocido)
15/10/2014 30/10/2014 Determinación de polifenoles dialdehídicos en aceite de oliva virgen extra (2349/0335) Dieta Mediterránea Aceites y Vinagres, S.A. (Desconocido)
26/12/2013 25/03/2014 Estudio de polifenoles en aceites de oliva virgen (2123/0335) Sociedad Agraria de Transformación N-1941 Santa Teresa (Desconocido)
15/10/2012 14/11/2012 Análisis de uan disolución acuosa de extracto microbiano, conteniendo cloruro potásico, de uso como fitofortificante. (1696/0335) MIP SYSTEM AGRO, S.L. (Desconocido)
28/07/2010 27/08/2010 Estudio del formulado BIOMIN (0893/0335) Biofal 2002 S.L. (Desconocido)
01/04/2010 31/03/2011 Estudio sobre la descomposición de alcaloides contenidos en las aguas de desamargamiento de la semilla de altramuz (Lupinus Albus). (0679/0335) HERMABAR, S.L. (Desconocido)
05/05/2008 05/02/2009 Estudio de los alcaloides quinolizidinicos y proteinas contenidos en extractos de lupinus albus (Principalmente Lupanima) (OG-054/08) Biofal 2002 S.L. (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/01/2007 31/12/2008 Nitroalkanes as carbanions in the sugar chemistry (HI2006-0130) Ministerio de Educación y Ciencia (Nacional) 11.260,00 €

Patentes

Nº Solicitud Fecha Solicitud Fecha Concesión Nombre
P201830049 10/03/2017 26/11/2019 Procedimiento para la obtención de secoiridoides dialdehídicos
P201131161 08/07/2011 09/04/2014 Procedimiento para la obtención de extracto de hidroxitirosol, extracto mezcla de hidroxitirosol y 3,4-dihidroxifenilglicol, y extracto de acetato de hidroxitirosilo, a partir de subproductos del olivo y su purificación.
P201400568 30/06/2014 15/04/2016 Uso como antioxidantes de compuestos organoselénicos fenólicos y sus composiciones
P201100639 03/06/2011 03/09/2013 Compuestos bioactivos polifenólicos conteniendo azufre o selenio y sus usos
P201400374 05/05/2014 05/05/2016 Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación
P201500558 05/05/2014 08/08/2016 Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación
P201700241 10/03/2017 06/11/2019 Procedimiento para la obtención de secoiridoides dialdehídicos
P201500560 05/05/2014 08/08/2016 Cepas bacterianas y sus usos en reacciones de acilación y/o desacilación
P201930815 20/09/2019 - Procedimiento para la extracción en hoja de olivo de oleuropeína en una fracción fenólica, composición alimentaria funcional y uso
P201301123 28/11/2013 17/12/2015 Procedimiento de estabilización de las aguas de procesado de semilla de Lupinus spp., extracción de alcaloides y su uso como biocida ecológico
P201500146 05/05/2014 03/10/2016 Derivados acilados de polifenoles y/o carbohidratos, métodos de obtención y usos de los mismos
P201300916 24/09/2013 29/01/2016 Nuevos antiiflamatorios basados en polifenoles del olivo
P201500145 05/05/2014 20/10/2016 Derivados acilados de carbohidratos, métodos de obtención y usos de los mismos