Andrés Aguilera López

Catedrático de Universidad

aguilo@us.es

Área de conocimiento: Genética

Departamento: Genética

Grupo: INESTABILIDAD GENOMICA Y CANCER - BIO-102 (Universidad de Sevilla)

Unidad de excelencia: Unidad de excelencia CABIMER (CABIMER excelencia)

Centro mixto: CABIMER (CABIMER)

Prog. doctorado: Prog.Doct.en Biología Molecular, Biomedicina e Investigac.Clínica (RD.2011)

0000-0003-4782-1714

L-1825-2014

55936440400

uA2X0YYAAAAJ

2529590

629

Artículo: 180

Resumen congreso: 3

Capítulo: 11

Libro: 3

Revisión: 34

Corrección: 5

Editorial: 8

Nota: 4

Ponencia: 15

Letter: 1

TOTAL: 264

Tipo	Año	Título	Fuente
Artículo	2024	Rat1 promotes premature transcription termination at R-loops	NUCLEIC ACIDS RESEARCH
Artículo	2024	SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability	CELL REPORTS
Artículo	2023	Actin nucleators safeguard replication forks by limiting nascent strand degradation	NUCLEIC ACIDS RESEARCH
Artículo	2023	Break-induced RNA-DNA hybrids (BIRDHs) in homologous recombination: friend or foe?	EMBO REPORTS
Artículo	2023	DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops.	CELL REPORTS
Artículo	2023	DICER ribonuclease removes harmful R-loops	MOLECULAR CELL
Artículo	2023	Spontaneous deamination of cytosine to uracil is biased to the non-transcribed DNA strand in yeast	DNA REPAIR
Artículo	2023	The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts	NATURE COMMUNICATIONS
Artículo	2022	A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability.	GENETICS
Resumen congreso	2022	Chromatin modifications upon transcription-dependent or independent replication stress	ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Capítulo	2022	Detection of R-Loops by In Vivo and In Vitro Cytosine Deamination in Saccharomyces cerevisiae	R-Loops: methods and protocols
Capítulo	2022	Genome-Wide Analysis of DNA-RNA Hybrids in Yeast by DRIPc-Seq and DRIP-Seq	R-Loops: methods and protocols
Resumen congreso	2022	Mechanisms for RNA-mediated genome instability	ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Artículo	2022	MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells	CELL REPORTS
Libro	2022	R-Loops: methods and protocols	R-Loops: methods and protocols
Capítulo	2022	RNase H1 Hybrid-Binding Domain-Based Tools for Cellular Biology Studies of DNA–RNA Hybrids in Mammalian Cells	R-Loops: methods and protocols
Artículo	2022	Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability	CELL REPORTS
Artículo	2022	WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage.	NATURE COMMUNICATIONS
Artículo	2021	A CDK-regulated chromatin segregase promoting chromosome replication.	NATURE COMMUNICATIONS
Revisión	2021	A new interaction between BRCA2 and DDX5 promotes the repair of DNA breaks at transcribed chromatin	MOLECULAR & CELLULAR ONCOLOGY
Artículo	2021	A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells	NATURE COMMUNICATIONS
Artículo	2021	ADAR-mediated RNA editing of DNA: RNA hybrids is required for DNA double strand break repair.	NATURE COMMUNICATIONS
Capítulo	2021	Analysis of repair of replication-born double-strand breaks by sister chromatid recombination in yeast	The DNA replication-repair interface
Artículo	2021	BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair	EMBO JOURNAL
Corrección	2021	Corrigendum: UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide.	GENES & DEVELOPMENT
Capítulo	2021	Detection of DNA Double-Strand Breaks by γ-H2AX Immunodetection	Homologous recombination: methods and protocols
Artículo	2021	DNA-RNA hybrids at DSBs interfere with repair by homologous recombination.	eLife
Artículo	2021	Harmful R-loops are prevented via different cell cycle-specific mechanisms	NATURE COMMUNICATIONS
Revisión	2021	Heterogeneity of DNA damage incidence and repair in different chromatin contexts	DNA REPAIR
Editorial	2021	Homologous recombination methods and protocols preface	Homologous recombination: methods and protocols
Libro	2021	Homologous recombination: methods and protocols	Homologous recombination: methods and protocols
Revisión	2021	Origin matters: spontaneous DNA–RNA hybrids do not form in trans as a source of genome instability	CURRENT GENETICS
Editorial	2021	Preface	Methods in molecular biology
Artículo	2021	R-loop-mediated ssDNA breaks accumulate following short-term exposure to the HDAC inhibitor romidepsin.	MOLECULAR CANCER RESEARCH
Artículo	2021	The human nucleoporin Tpr protects cells from RNA-mediated replication stress.	NATURE COMMUNICATIONS
Artículo	2021	The role of chromatin at transcription-replication conflicts as a genome safeguard.	BIOCHEMICAL SOCIETY TRANSACTIONS
Capítulo	2021	The sister-chromatid exchange assay in human cells	Homologous recombination: methods and protocols
Artículo	2021	The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription-replication conflicts	NATURE GENETICS
Nota	2021	The SWI/SNF complex, transcription-replication conflicts and cancer: a connection with high therapeutic potential	MOLECULAR & CELLULAR ONCOLOGY
Artículo	2021	THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans	JOURNAL OF CELL SCIENCE
Artículo	2021	VID22 counteracts G-quadruplex-induced genome instability.	NUCLEIC ACIDS RESEARCH
Artículo	2020	Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner	eLife
Revisión	2020	Histone deacetylases facilitate the accurate repair of broken forks	MOLECULAR & CELLULAR ONCOLOGY
Artículo	2020	Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage	MICROBIAL CELL
Artículo	2020	Homologous recombination and Mus81 promote replication completion in response to replication fork blockage	EMBO REPORTS
Revisión	2020	Looping the (R) Loop in DSB Repair via RNA Methylation	MOLECULAR CELL
Revisión	2020	Spontaneous DNA-RNA hybrids: differential impacts throughout the cell cycle	CELL CYCLE
Artículo	2020	TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loopmediated DNA damage	PLOS GENETICS
Artículo	2020	UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide	GENES & DEVELOPMENT
Nota	2019	A conversation with Andrés Aguilera	COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES
Artículo	2019	A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs	CELL REPORTS
Artículo	2019	Depletion of the MFAP1/SPP381 splicing factor causes R-loop-independent genome instability	CELL REPORTS
Artículo	2019	Elongation factor TFIIS prevents transcription stress and R-loop accumulation to maintain genome stability	MOLECULAR CELL
Revisión	2019	Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways	MICROBIAL CELL
Revisión	2019	R Loops: From Physiological to Pathological Roles	CELL
Artículo	2019	R-Loops as Promoters of Antisense Transcription	MOLECULAR CELL
Artículo	2019	Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion	NATURE COMMUNICATIONS
Artículo	2019	The antitumor drugs trabectedin and lurbinectedin induce transcription-dependent replication stress and genome instability	MOLECULAR CANCER RESEARCH
Artículo	2019	The DNA damage response acts as a safeguard against harmful DNA-RNA hybrids of different origins	EMBO REPORTS
Artículo	2019	The Nup84 complex coordinates the DNA damage response to warrant genome integrity	NUCLEIC ACIDS RESEARCH
Revisión	2019	The THO complex as a paradigm for the prevention of cotranscriptional R-loops	COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES
Revisión	2019	Transcription-mediated replication hindrance: A major driver of genome instability	GENES & DEVELOPMENT
Revisión	2019	What causes an RNA-DNA hybrid to compromise genome integrity?	DNA REPAIR
Artículo	2018	Coordinated activity of Y family TLS polymerases and EXO1 protects non-S phase cells from UV-induced cytotoxic lesions	MOLECULAR CELL
Corrección	2018	Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions (vol 70, pg 34, 2018)	MOLECULAR CELL
Capítulo	2018	Detection of DNA-RNA hybrids in vivo	GENOME INSTABILITY: METHODS AND PROTOCOLS
Artículo	2018	Epigenetic features of human telomeres	NUCLEIC ACIDS RESEARCH
Artículo	2018	Gene gating at nuclear pores prevents the formation of R loops	MOLECULAR & CELLULAR ONCOLOGY
Artículo	2018	Guidelines and recomendations on yeast cell death nomenclature	MICROBIAL CELL
Artículo	2018	Human mitochondrial degradosome prevents harmful mitochondria! R loops and mitochondrial genome instability	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo	2018	Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts	NATURE COMMUNICATIONS
Artículo	2018	Yra1-bound RNA-DNA hybrids cause orientation-independent transcription-replication collisions and telomere instability	GENES & DEVELOPMENT
Artículo	2017	A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination	PLOS GENETICS
Artículo	2017	Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells	DNA REPAIR
Corrección	2017	Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange (vol 32, 1592, 2012)	MOLECULAR AND CELLULAR BIOLOGY
Revisión	2017	DNA-RNA hybrids: the risks of DNA breakage during transcription	NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo	2017	Histone Mutants Separate R Loop Formation from Genome Instability Induction	MOLECULAR CELL
Artículo	2017	Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability	EMBO JOURNAL
Artículo	2017	Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Revisión	2017	The need to regulate replication fork speed	SCIENCE
Revisión	2017	The Role of Replication-Associated Repair Factors on R-Loops	GENES
Artículo	2017	The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage	PLOS GENETICS
Artículo	2016	Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere Shortening	PLOS GENETICS
Artículo	2016	FANCD2 Facilitates Replication through Common Fragile Sites	MOLECULAR CELL
Artículo	2016	High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast	PLOS GENETICS
Ponencia	2016	Role of Chromatin and the DNA Damage Response in RNA-Mediated Genome Instability.	ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Artículo	2016	Roles of human POLD1 and POLD3 in genome stability	Scientific reports
Corrección	2016	The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development (vol 7, e52447, 2012)	PLOS ONE
Revisión	2016	Transcription as a Threat to Genome Integrity	ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85
Revisión	2016	Transcription-replication conflicts: how they occur and how they are resolved	NATURE REVIEWS MOLECULAR CELL BIOLOGY
Artículo	2015	A unified model for the molecular basis of Xeroderma pigmentosum - Cockayne Syndrome	RARE DISEASES
Artículo	2015	Interdependence of the Rad50 Hook and Globular Domain Functions	MOLECULAR CELL
Artículo	2015	Methods to Study Transcription-Coupled Repair in Chromatin	CHROMATIN PROTOCOLS, 3RD EDITION
Artículo	2015	Polycomb RING1A-and RING1B-dependent histone H2A monoubiquitylation at pericentromeric regions promotes S-phase progression	JOURNAL OF CELL SCIENCE
Revisión	2015	R loops: new modulators of genome dynamics and function	NATURE REVIEWS GENETICS
Ponencia	2015	R-loop-mediated genome instability in histone mutants	YEAST
Ponencia	2015	R-loops as a source of genome instability in yeast and cancer cells	YEAST
Revisión	2015	Replication stress and cancer	Nature Reviews. Cancer
Artículo	2015	RNA polymerase II contributes to preventing transcription-mediated replication fork stalls	EMBO JOURNAL
Artículo	2015	Role for RNA: DNA hybrids in origin-independent replication priming in a eukaryotic system	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo	2015	The Fanconi anemia pathway protects genome integrity from R-loops	PLOS GENETICS
Ponencia	2015	The role of the Mlp1 in genomic stability	YEAST
Artículo	2014	A genome-wide function of THSC/TREX-2 at active genes prevents transcription-replication collisions	NUCLEIC ACIDS RESEARCH
Artículo	2014	BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2	NATURE
Artículo	2014	Cleavage Factor I Links Transcription Termination to DNA Damage Response and Genome Integrity Maintenance in Saccharomyces cerevisiae	PLOS GENETICS
Artículo	2014	Npl3, a new link between RNA-binding proteins and the maintenance of genome integrity	CELL CYCLE
Artículo	2014	The rem Mutations in the ATP-Binding Groove of the Rad3/XPD Helicase Lead to Xeroderma pigmentosum-Cockayne Syndrome-Like Phenotypes	PLOS GENETICS
Artículo	2014	The yeast and human FACT chromatinreorganizing complexes solve R-loop-mediated transcription-replication conflicts	GENES & DEVELOPMENT
Artículo	2014	Transcription and Recombination: When RNA Meets DNA	COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
Artículo	2014	Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability	MOLECULAR CELL
Revisión	2013	Causes of Genome Instability	ANNUAL REVIEW OF GENETICS, VOL 47
Artículo	2013	Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination	NUCLEIC ACIDS RESEARCH
Artículo	2013	Coordinated control of replication and transcription by a SAPK protects genomic integrity	NATURE
Artículo	2013	Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid	PLOS GENETICS
Artículo	2013	R loops are linked to histone H3 S10 phosphorylation and chromatin condensation	MOLECULAR CELL
Artículo	2013	R-Loop Mediated Transcription-Associated Recombination in trf4 Delta Mutants Reveals New Links between RNA Surveillance and Genome Integrity	PLOS ONE
Capítulo	2013	R-Loops	Brenner's Encyclopedia of Genetics: Second Edition
Ponencia	2013	Replication impairment as a source of transcription- and R-loop-associated recombination	JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
Artículo	2013	The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability	GENES & DEVELOPMENT
Revisión	2013	Transcription coupled repair at the interface between transcription elongation and mRNP biogenesis	BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Revisión	2013	Transcription-Associated Genome Instability	CHEMICAL REVIEWS
Artículo	2013	Yeast Pol4 Promotes Tel1-Regulated Chromosomal Translocations	PLOS GENETICS
Artículo	2012	Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor	EMBO JOURNAL
Artículo	2012	Complex Chromosomal Rearrangements Mediated by Break-Induced Replication Involve Structure-Selective Endonucleases	PLOS GENETICS
Artículo	2012	Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange	MOLECULAR AND CELLULAR BIOLOGY
Ponencia	2012	Histone 3 K4, K14 and K56 post-translational modifications are not affected in hpr1 Delta	FEBS JOURNAL
Revisión	2012	New clues to understand the role of THO and other functionally related factors in mRNP biogenesis	BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Ponencia	2012	New insights into the function of THO/TREX mRNP biogenesis and export factor in yeast and human cells	FEBS JOURNAL
Revisión	2012	R Loops: From Transcription Byproducts to Threats to Genome Stability	MOLECULAR CELL
Artículo	2012	R-loops cause replication impairment and genome instability during meiosis	EMBO REPORTS
Ponencia	2012	R-loops in recombination-mediated genome instability	FEBS JOURNAL
Artículo	2012	The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development	PLOS ONE
Artículo	2012	Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes	NUCLEIC ACIDS RESEARCH
Ponencia	2012	Topological stress and genome integrity maintenance	FEBS JOURNAL
Artículo	2011	A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors	EMBO JOURNAL
Artículo	2011	AID Induces Double-Strand Breaks at Immunoglobulin Switch Regions and c-MYC Causing Chromosomal Translocations in Yeast THO Mutants	PLOS GENETICS
Artículo	2011	Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo	2011	Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers	BMC CANCER
Revisión	2011	Dna strand break repair and human genetic disease	ENCYCLOPEDIA OF LIFE SCIENCES (ELS)
Capítulo	2011	Genetic and Molecular Analysis of Mitotic Recombination in Saccharomyces cerevisiae	DNA Recombination: Methods and Protocols
Artículo	2011	Genome instability and transcription elongation impairment in human cells depleted of THO/TREX	PLOS GENETICS
Artículo	2011	Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles	EMBO JOURNAL
Artículo	2011	Nab2 functions in the metabolism of RNA driven by polymerases II and III	MOLECULAR BIOLOGY OF THE CELL
Artículo	2011	New Suppressors of THO Mutations Identify Thp3 (Ypr045c)-Csn12 as a Protein Complex Involved in Transcription Elongation	MOLECULAR AND CELLULAR BIOLOGY
Artículo	2011	The Rad50 coiled-coil domain is indispensable for Mre11 complex functions	NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo	2011	The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear Pores	CELL
Artículo	2011	Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability	MOLECULAR CELL
Artículo	2011	Zim17/Tim15 links mitochondrial iron-sulfur cluster biosynthesis to nuclear genome stability	NUCLEIC ACIDS RESEARCH
Artículo	2010	A Postincision-Deficient TFIIH Causes Replication Fork Breakage and Uncovers Alternative Rad51-or Pol32-Mediated Restart Mechanisms	MOLECULAR CELL
Artículo	2010	Replication fork breakage and re-start New insights into Rad3/XPD-associated deficiencies	CELL CYCLE
Revisión	2010	The interface between transcription and mRNP export: From THO to THSC/TREX-2	BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Revisión	2010	The THO complex as a key mrnp biogénesis factor in development and cell differentiation	Journal Of Biology (London. Print)
Artículo	2009	Chromosomal Translocations Caused by Either Pol32-Dependent or Pol32-Independent Triparental Break-Induced Replication	MOLECULAR AND CELLULAR BIOLOGY
Revisión	2009	DNA Repair in Mammalian Cells	CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo	2009	Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair	PLOS GENETICS
Artículo	2009	Methods to study transcription-coupled repair in chromatin.	CHROMATIN PROTOCOLS, 3RD EDITION
Artículo	2009	R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX	NUCLEIC ACIDS RESEARCH
Artículo	2009	Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery	JOURNAL OF CELL BIOLOGY
Artículo	2009	Stimulation of direct-repeat recombination by RNA polymerase III transcription	DNA REPAIR
Artículo	2009	The Dot1 Histone Methyltransferase and the Rad9 Checkpoint Adaptor Contribute to Cohesin-Dependent Double-Strand Break Repair by Sister Chromatid Recombination in Saccharomyces cerevisiae	GENETICS
Artículo	2009	The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants	MOLECULAR AND CELLULAR BIOLOGY
Artículo	2009	The Stress-activated Protein Kinase Hog1 Mediates S Phase Delay in Response to Osmostress	MOLECULAR BIOLOGY OF THE CELL
Editorial	2009	Transcription at the proximity of the nuclear pore A role for the THP1-SAC3-SUS1-CDC31 (THSC) complex	RNA BIOLOGY
Artículo	2008	A Novel Class of mRNA-containing Cytoplasmic Granules Are Produced in Response to UV-Irradiation	MOLECULAR BIOLOGY OF THE CELL
Artículo	2008	A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants	MOLECULAR GENETICS AND GENOMICS
Revisión	2008	Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus	CHROMOSOMA
Artículo	2008	CDK targets Sae2 to control DNA-end resection and homologous recombination	NATURE
Artículo	2008	Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity	MOLECULAR GENETICS AND GENOMICS
Revisión	2008	Genome instability: a mechanistic view of its causes and consequences	NATURE REVIEWS GENETICS
Artículo	2008	The THP1-SAC3-SUS1-CDC31 Complex Works in Transcription Elongation-mRNA Export Preventing RNA-mediated Genome Instability	MOLECULAR BIOLOGY OF THE CELL
Artículo	2007	A new connection of mRNP biogenesis and export with transcription-coupled repair	NUCLEIC ACIDS RESEARCH
Artículo	2007	Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo	2007	Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication	NUCLEIC ACIDS RESEARCH
Editorial	2007	How to exchange your partner. Workshop on recombination mechanisms and the maintenance of genomic stability	EMBO REPORTS
Artículo	2007	Impairment of transcription elongation by R-loops in vitro	BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Libro	2007	Molecular genetics of recombination	Molecular genetics of recombination
Artículo	2007	Nucleoporins prevent DNA damage accumulation by modulating Ulp1-dependent sumoylation processes	MOLECULAR BIOLOGY OF THE CELL
Artículo	2007	Sister chromatid recombination	Topics in Current Genetics
Artículo	2007	SMC proteins, new players in the maintenance of genomic stability	CELL CYCLE
Artículo	2006	An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination	MOLECULAR AND CELLULAR BIOLOGY
Editorial	2006	DNA repair: From molecular mechanism to human disease	DNA REPAIR
Artículo	2006	Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange	EMBO REPORTS
Artículo	2006	Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex	MOLECULAR AND CELLULAR BIOLOGY
Artículo	2006	Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination	NATURE CELL BIOLOGY
Artículo	2006	Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants	MOLECULAR AND CELLULAR BIOLOGY
Revisión	2005	Cotranscriptional mRNP assembly: from the DNA to the nuclear pore	CURRENT OPINION IN CELL BIOLOGY
Artículo	2005	Impairment of replication fork progression mediates RNA polII transcription-associated recombination	EMBO JOURNAL
Artículo	2005	Interdependence between transcription and mRNP processing and export, and its impact on genetic stability	MOLECULAR CELL
Editorial	2005	mRNA processing and genomic instability	NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo	2005	Partial depletion of histone h4 increases homologous recombination-mediated genetic instability	MOLECULAR AND CELLULAR BIOLOGY
Artículo	2004	A novel yeast mutation, rad52-L89F, causes a specific defect in Rad51-independent recombination that correlates with a reduced ability of RAD52-L89F to interact with RAD59	GENETICS
Letter	2004	A unified nomenclature for protein subunits of Mediator complexes linking transcriptional regulators to RNA polymerase II	MOLECULAR CELL
Artículo	2004	Molecular evidence indicating that the yeast PAF complex is required for transcription elongation	EMBO REPORTS
Artículo	2004	The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange	EMBO REPORTS
Ponencia	2003	Analysis of replication fork movement in mutants defective in RNA polymerase II transcription elongation.	YEAST
Editorial	2003	Control of cross-over by single-strand DNA resection	TRENDS IN GENETICS
Artículo	2003	Cotranscriptionally formed DNA : RNA hybrids mediate transcription elongation impairment and transcription-associated recombination	MOLECULAR CELL
Artículo	2003	Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast	MOLECULAR CELL
Ponencia	2003	Equal sister-chromatid exchange is a major mechanism of double-strand-break repair in yeast	YEAST
Ponencia	2003	Impairment of chromatin assembly confers hyperrecombination.	YEAST
Revisión	2003	Mitotic recombination in Saccharomyces cerevisiae	CURRENT GENETICS
Artículo	2003	Molecular evidence for a positive role of Spt4 in transcription elongation	EMBO JOURNAL
Artículo	2003	Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation	JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo	2003	Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism	JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo	2003	Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae: New insights into transcription-associated recombination	GENETICS
Artículo	2003	Relationship between G+C content, ORF-length and mRNA concentration in Saccharomyces cerevisiae	YEAST
Artículo	2002	Characterization of two highly similar Rad51 homologs of Physcomitrella patens	JOURNAL OF MOLECULAR BIOLOGY
Artículo	2002	Defective nucleotide excision repair in yeast hpr1 and tho2 mutants	NUCLEIC ACIDS RESEARCH
Artículo	2002	La recombinación homóloga del ADN	Investigación y Ciencia
Revisión	2002	The connection between transcription and genomic instability	EMBO JOURNAL
Artículo	2002	The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability	EMBO JOURNAL
Artículo	2002	Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae	GENETICS
Artículo	2002	TREX is a conserved complex coupling transcription with messenger RNA export	NATURE
Artículo	2001	A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination	GENETICS
Editorial	2001	Double-strand break repair: are Rad51/RecA-DNA joints barriers to DNA replication?	TRENDS IN GENETICS
Ponencia	2001	Genetic and molecular characterization of THO1, a multicopy supressor of, hpr1.	YEAST
Ponencia	2001	Genetics and molecular analysis of thp1, a yeast gene controlling transcription and recombination.	YEAST
Artículo	2001	Hpr1 is preferentially required for transcription of either long or G+C-Rich DNA sequences in Saccharomyces cerevisiae	MOLECULAR AND CELLULAR BIOLOGY
Ponencia	2001	Isolation and genetic analysis of novel HPR1 and THO2 mutations that differentially affect transcription and recombination.	YEAST
Capítulo	2001	Mechanisms and genetic control of dna repeat recombination in s. cerevisiae	Recent Research Developments in Human Genetics
Artículo	2001	Yeast spt6-140 mutation, affecting chromatin and transcription, preferentially increases recombination in which Rad51p-mediated strand exchange is dispensable	GENETICS
Artículo	2000	A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae	EMBO JOURNAL
Revisión	2000	Mitotic recombination in yeast: elements controlling its incidence	YEAST
Artículo	2000	RAD52-dependent and -independent homologous recombination initiated by Flp recombinase at a single FRT site flanked by direct repeats	MOLECULAR & GENERAL GENETICS
Artículo	1999	Construction and genetic analysis of S-cerevisiae deletants of six novel ORFs from chromosome II	YEAST
Artículo	1998	A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination	EMBO JOURNAL
Artículo	1998	Genetic stability and DNA rearrangements associated with a 2 x 1.1-kb perfect palindrome in Escherichia coli	MOLECULAR & GENERAL GENETICS
Artículo	1997	Recombination between DNA repeats in yeast hpr1 Delta cells is linked to transcription elongation	EMBO JOURNAL
Artículo	1997	The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability	GENES & DEVELOPMENT
Artículo	1997	The yeast HRS1 gene is involved in positive and negative regulation of transcription and shows genetic characteristics similar to SIN4 and GAL11	GENETICS
Artículo	1996	Differential intrachromosomal hyper-recombination phenotype of spt4 and spt6 mutants of S-cerevisiae	CURRENT GENETICS
Artículo	1996	La recombinación genética y su relación con la transcripción	Industria Farmacéutica
Revisión	1996	Mutations in the yeast SRB2 general transcription factor suppress hpr1- induced recombination and show defects in DNA repair	GENETICS
Artículo	1996	The yeast HRS1 gene encodes a polyglutamine-rich nuclear protein required for spontaneous and hpr1-induced deletions between direct repeats	GENETICS
Artículo	1995	Genetic-evidence for different rad52-dependent intrachromosomal recombination pathways in saccharomyces-cerevisiae	CURRENT GENETICS
Artículo	1995	Isolation and genetic analysis of extragenic suppressors of the hyper- deletion phenotype of the Saccharomyces cerevisiae hpr1Δ mutation	GENETICS
Corrección	1995	Isolation and genetic analysis of extragenic suppressors of the hyper-deletion phenotype of the Saccharomyces cerevisiae hpr1Δ mutation (Genetics (January, 1995) 139 (57-66))	GENETICS
Capítulo	1995	Recombinación y estabilidad de secuencias repetidas de ADN en levaduras	Microbiología y genética molecular
Artículo	1995	Role of reciprocal exchange, one-ended invasion crossover and single- strand annealing on inverted and direct repeat recombination in yeast: Different requirements for the RAD1, RAD10, and RAD52 genes	GENETICS
Artículo	1994	Formamide sensitivity: A novel conditional phenotype in yeast	GENETICS
Artículo	1994	Increase in incidence of chromosome instability and nonconservative recombination between repeats in saccharomyces-cerevisiae hpr1-delta strains	MOLECULAR & GENERAL GENETICS
Nota	1994	New in-vivo cloning methods by homologous recombination in yeast	CURRENT GENETICS
Artículo	1991	The hyper-gene conversion hpr5-1 mutation of Saccharomyces cerevisiae is an allele of the SRS2/RADH gene	GENETICS
Artículo	1990	High-levels of chromosome instability in polyploids of saccharomyces-cerevisiae	Mutation Research
Artículo	1990	Hpr1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the saccharomyces-cerevisiae top1 gene	MOLECULAR AND CELLULAR BIOLOGY
Artículo	1990	Molecular analysis of RGP1, a new yeast gene required for proper mitotic growth	NUCLEIC ACIDS RESEARCH
Artículo	1990	Nucleotide-sequence and characterization of temperature-sensitive pol1 mutants of saccharomyces-cerevisiae	GENE
Resumen congreso	1989	ANALYSIS OF HYPER-RECOMBINATION MUTANTS OF YEAST	GENETICS
Artículo	1989	Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1	GENETICS
Artículo	1989	Synergistic effects of ethanol and temperature on yeast mitochondria	CURRENT MICROBIOLOGY
Artículo	1989	The phosphofructokinase genes of yeast evolved from two duplication events	GENE
Artículo	1989	Yeast intrachromosomal recombination: long gene conversion tracts are preferentially associated with reciprocal exchange and require the RAD1 and RAD3 gene products	GENETICS
Artículo	1988	Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.	GENETICS
Artículo	1988	Mitotic gene conversion of large DNA heterologies in saccharomyces-cerevisiae	MOLECULAR & GENERAL GENETICS
Nota	1988	Relationship between growth, fermentation, and respiration rates in saccharomyces cerevisiae - a study based on the analysis of the yield ypx	BIOTECHNOLOGY AND BIOENGINEERING
Artículo	1987	Mutations suppressing the effects of a deletion of the phosphoglucose isomerase gene pgi1 in saccharomyces-cerevisiae	CURRENT GENETICS
Artículo	1986	Deletion of the phosphoglucose isomerase structural gene makes growth and sporulation glucose dependent in saccharomyces-cerevisiae	MOLECULAR & GENERAL GENETICS
Artículo	1986	Ethanol-sensitive mutants of Saccharomyces-cerevisiae	ARCHIVES OF MICROBIOLOGY
Artículo	1986	Isolation and molecular analysis of the phosphoglucose isomerase structural gene of saccharomyces-cerevisiae	MOLECULAR & GENERAL GENETICS
Artículo	1985	Role of mitochondria in ethanol tolerance of saccharomyces-cerevisiae	ARCHIVES OF MICROBIOLOGY
Artículo	1985	Specific gene probes as tools in yeast taxonomy	CURRENT GENETICS
Artículo	1984	Instability of saccharomyces-cerevisiae heterokaryons	CURRENT GENETICS
Artículo	1983	Alcohol-and sucrose- tolerant wine yeast strains.	CIENCIA BIOLÓGICA
Artículo	1983	Selection of wine yeasts for growth and fermentation in the presence of ethanol and sucrose	APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genética y fisiología de la tolerancia al etanol en "Saccharomyces cerevisiae" (1983)
Dirigida por: Tahía Benítez Fernández

Tesis dirigidas/tutorizadas:42

Fecha lectura	Título	Rol
15/02/2024	Role of FACT and other chromatin-related factors in the origin of genetic instability	Director/a, Tutor/a
12/04/2023	Insights into RNA-mediated genome instability by altering ALY expression and the use of new drugs	Tutor/a, Director/a
22/04/2022	Global Dynamics of Topoisomerase II Activity	Director/a
28/10/2021	DDX47 and MECP2, two novel human functions controlling R-loop-mediated genome integrity	Tutor/a, Director/a
02/06/2021	INFLUENCE OF CHROMATIN FACTORS AND DNA-RNA HYBRIDS IN THE REPAIR OF REPLICATION-BORN DSBS	Tutor/a, Director/a
07/07/2020	THE INFLUENCE OF CHROMATIN IN DNA-RNA HYBRID METABOLISM	Director/a
12/02/2020	PAPEL DE LA HELICASA UAP56/DDX39B Y OTROS FACTORES ASOCIADOS AL METABOLISMO DEL ARN EN LA INTEGRIDAD DEL GENOMA	Director/a
08/11/2019	REGULATION OF BLOCKED-DSB REPAIR BY DNA-PKCS AND ATM KINASES	Tutor/a
23/10/2019	NEW FACTORS INVOLVED IN TRANSCRIPTION-ASSOCIATED GENOME INSTABILITY	Director/a
12/07/2019	New cellular elements associated with DNA:RNA hybrid homeostasis in eukaryotes	Director/a
06/07/2018	INESTABILIDAD GENÉTICA ASOCIADA A R-LOOPS	Director/a
29/09/2017	REGULATION OF TDP2 FUNCTION BY SUMO INTERACTIONS	Tutor/a
25/09/2017	PAPEL DE FACTORES DE LA TRANSCRIPCIÓN Y LA REPLICACIÓN DEL ADN EN EL ORIGEN DE LA INESTABILIDAD GENÓMICA	Director/a
22/09/2017	NEW INSIGHTS INTO CTIP PROTEIN: EXPRESSION IN BREAST CANCER AND REGULATION BY SUMOYLATION	Tutor/a
13/09/2017	NUEVOS GENES HUMANOS ASOCIADOS A LA BIOGÉNESIS DE MRNPS NECESARIOS PARA LA INTEGRIDAD DEL GENOMA	Director/a
08/09/2017	PAPEL DE LA CROMATINA EN LA FORMACIÓN DE R-LOOPS	Director/a
11/07/2017	FUNCIÓN DE LA SUMOILACIÓN EN EL DESARROLLO DEL SISTEMA NERVIOSO CENTRAL DE VERTEBRADOS	Tutor/a
16/06/2017	IDENTIFICACIÓN DE NUEVAS PROTEÍNAS QUE INTERACCIONAN CON CTIP: IMPLICACIÓN DE PRMT5 Y CCAR2 EN LA RESECCIÓN DEL ADN	Tutor/a
03/02/2017	ROLE OF ATM IN THE REPAIR OF BLOCKED DNA DOUBLE-STRAND BREAKS	Tutor/a
20/01/2017	CONSECUENCIAS DE LAS ALTERACIONES EN LA EXPRESIÓN DE AURORA QUINASA B SOBRE LA SEGREGACIÓN CROMOSÓMICA Y LA PROGRESIÓN DEL CICLO CELULAR	Tutor/a
19/12/2014	Implicación de los complejos TFIIH y FACT en el mantenimiento de la integridad del genoma	Director/a
15/07/2014	PAPEL DE NPL3, NUP84 Y OTROS FACTORES DE TRANSPORTE DE MRNA EN EL MANTENIMIENTO DE LA INTEGRIDAD DEL GENOMA	Director/a
20/12/2013	INESTABILIDAD GENÉTICA Y CAMBIOS EN LA CROMATINA EN MUTANTES DEL COMPLEJO THO EN MITOSIS Y MEIOSIS DE EUCARIOTAS MODELO	Director/a
14/09/2012	IMPLICACIÓN DE LA MAQUINARIA DE TRANSCRIPCIÓN EN EL ORIGEN DE LA INESTABILIDAD GENÉTICA	Director/a
23/02/2012	FENÓMENOS DE INESTABILIDAD GENÓMICA LIGADOS A LA TRANSCRIPCIÓN DEL DNA EN EUCARIOTAS	Director/a
03/03/2011	ANÁLISIS DE FACTORES QUE INTERVIENEN EN LA BIOGÉNESIS DEL ARNM Y LA ESTABILIDAD GENÓMICA EN CÉLULAS DE MAMÍFEROS	Director/a
02/03/2011	FACTORES IMPLICADOS EN LA REPARACIÓN DE ROTURAS DE DOBLE CADENA POR RECOMBINACIÓN ENTRE CROMÁTIDAS HERMANAS	Director/a
23/07/2010	INESTABILIDAD GENÉTICA ASOCIADA A DEFECTOS EN EL COMPLEJO TFIIH	Director/a
17/09/2009	CONEXIÓN ENTRE TRANSCRIPCIÓN, RECOMBINACIÓN Y TOPOLOGÍA DEL DNA	Director/a
03/07/2009	NEW SYSTEMS AND NEW FACTORS IN NUCLEAR AND MITOCHONDRIAL GENOMIC INSTABILITY IN YEAST	Director/a
10/06/2009	PAPEL DE THSC Y OTROS FACTORES DE BIOGÉNESIS DE LOS MRNAS EN TRANSCRIPCIÓN E INTEGRIDAD DE LOS GENOMAS	Director/a
05/03/2009	INESTABILIDAD GENÉTICA ASOCIADA A TRANSCRIPCIÓN	Director/a
21/07/2006	Reparación postreplicativa de cortes de doble cadena en Saccharomyces cerevisiae	Director/a
31/03/2005	CONEXIÓN ENTRE LA BIOGÉNESIS DEL mRNA Y LA INESTABILIDAD GENÓMICA	Director/a
07/06/2004	PAPEL DEL RNA EN EXPRESIÓN GENÉTICA Y RECOMBINACIÓN EN Saccharomyces cerevisiae	Director/a
07/03/2003	ELONGACIÓN DE LA TRANSCRIPCIÓN EN S CEREVISIAE:EL COMPLEJO THO Y FACTORES RELACIONADOS FUNCIONALMENTE	Director/a
27/02/2003	CONEXIÓN ENTRE RECOMBINACIÓN Y BIOGÉNESIS DE RNA: THPL Y OTRAS PROTEÍNAS FUNCIONALMENTE RELACIONADAS	Director/a
05/04/2002	RELACIÓN ENTRE REPARACIÓN, RECOMBINACIÓN, Y TRANSCRIPCIÓN EN LEVADURAS	Director/a
19/07/2000	Recombinación mitótica entre repeticiones invertidas de ADN en Saccharomyces cerevisiae	Director/a
1996	Control genético de las deleciones entre secuencias repetidas directas en Saccaromyces cerevisiae	Director/a
1996	Recombinación entre secuencias repetidas e S. Cerevisiae: Análisis genético y molecular de la mutación HPR1 y de genes supresores de la misma	Director/a
1998	Relación de la transcripción con la recombinación entre secuencias repetidas en S. cerevisiae	Director/a

Proyectos de Investigación: 24

Contratos: 4

Ayudas: 4

Redes de Investigación: 4

Infraestructura: 6

Sobre los datos de Financiación (proyectos de investigación, contratos, ayudas, etc.):

Solo recogemos de SICA los datos anteriores al año 2000 y no habrá más actualizaciones por el momento desde esta plataforma.
Recogemos de SISIUS los proyectos estatales, autonómicos e internacionales gestionados por la US, siempre a partir del año 2000. Ver política de inclusión en SISIUS para más información.
Proyectos externos: se está creando un procedimiento dentro de la US para recoger de forma ordenada y exhaustiva la documentación relativa a estos proyectos, que se comunicará próximamente. Esto posibilitará que se incluyan convenientemente en SISIUS y después en Prisma. Hasta entonces, no se incluyen en Prisma los proyectos externos, aunque haya alguna referencia en SISIUS.
Ayudas procedentes del Plan Propio: se va a crear un apartado específico para esta financiación. Hasta entonces, no se incluyen las ayudas del Plan Propio en Prisma.

Fecha de la última carga desde SISIUS: 22/04/2024
Cualquier duda sobre este apartado, escríbanos al correo bibliometria@us.es

Proyectos de Investigación

Fecha de inicio	Fecha de fin	Rol	Denominación	Agencia financiadora
01/09/2023	31/08/2026	Responsable	Función de la cromatina en la inestabilidad genómica asociada a transcripción (PID2022-138251NB-I00)	Ministerio de Ciencia e Innovación (Nacional)
15/12/2022	15/12/2025	Responsable	R-loop-mediated genome instability factors in cancer (HR22-00073)	Fundación La Caixa (Autonómico)
01/01/2022	31/05/2023	Investigador/a	Replication fork stability and arrest in eukaryotic cells (US-1380058)	Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
01/10/2021	01/04/2024	Responsable	Replication and post-replication signalling pathways Regulating R-loop-associated Telomere instability in human cells RteRloop (101027467)	Comisión Europea (Europeo)
01/06/2020	30/11/2023	Responsable	Mecanismos de Inestabilidad Genómica Mediada por ARN y Reparación (PID2019-104270GB-I00)	Ministerio de Ciencia, Innovación y Universidades (Nacional)
01/02/2020	30/04/2022	Responsable	Modificaciones de histonas y proteínas de unión a ARN en el origen de la inestabilidad genética (US-1258654)	Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)
01/01/2020	31/03/2023	Responsable	Respuesta transcriptional en cis a la presencia de daño en el DNA (P18-FR-655)	Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)
30/12/2016	31/12/2020	Responsable	Transcription y Replication como Fuentes de Inestabilidad Genética (BFU2016-75058-P)	Ministerio de Economía y Competitividad (Nacional)
01/09/2016	31/12/2019	Responsable	Descubrimiento de antitumorales innovadores dirigidos contra dianas oncológicas: sistema topoisomerasa y regulación la respuesta inmune- INMUNOTOP (RTC-2016-4611-1)	Ministerio de Economía, Industria y Competitividad (Nacional)
01/12/2015	30/11/2021	Responsable	R-loops as a major modulator of transcription-associated recombination and chromatin dynamics (TARLOOP) (2628/0721)	Comisión Europea (Europeo)
01/01/2015	31/12/2017	Responsable	RNA-DNA Hybrids as a source of genome instability in cancer (15-0098)	Worldwide Cancer Research (Europeo)
30/01/2014	16/02/2019	Responsable	Origen de la Inestabilidad Cromosómica Asociada a Defectos en Transcripción y Replicación (P12-BIO-1238)	Consejería de Economía, Innovación y Ciencia (Autonómico)
01/01/2014	30/06/2017	Responsable	Inestabilidad Genómica Asociada a Transcripción e Híbridos DNA-RNA (BFU2013-42918-P)	Ministerio de Economía y Competitividad (Nacional)
01/01/2011	30/11/2014	Responsable	Roturas de ADN Asociadas a Replicación y Reparación por Recombinación de Genomas Eucarióticos (BFU2010-16372)	Ministerio de Ciencia e Innovación (Nacional)
03/02/2010	01/12/2013	Responsable	Bases Genéticas y Moleculares del Origen de la Inestabilidad Genomica en Eucariotas (P09-CVI-4567)	Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
31/01/2008	30/11/2011	Responsable	Genómica Funcional de la Interconexión Transcripción -Transporte de ARN (P07-CVI-02549)	Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/10/2007	09/12/2013	Responsable	Inestabilidad genómica (CSD2007-00015)	Ministerio de Educación y Ciencia (Nacional)
01/10/2006	30/09/2011	Responsable	Bases genéticas y moleculares de la inestabilidad genómica y su relación con la biogénesis de los mRNPs de eucariotas (BFU2006-05260)	Ministerio de Educación y Ciencia (Nacional)
01/03/2006	28/02/2009	Responsable	Bases genéticas y moleculares del origen de la inestabilidad genética en eucariotas (EXC/2005/CVI-624)	Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico)
15/11/2003	14/04/2007	Responsable	Inestabilidad genética asociada a transcripción en eucariotas (SAF2003-00204)	Ministerio de Ciencia y Tecnología (Nacional)
28/12/2001	27/12/2004	Responsable	Saccharomyces cerevisiae como modelo eucariótico para el estudio genómico y proteómico de la respuesta celular al estres (GEN2001-4707-C08-02)	Ministerio de Ciencia y Tecnología (Nacional)
20/12/2000	20/12/2003	Responsable	Recombinación entre secuencias repetidas e inestabilidad genética en saccharomyces cerevisiae: un modelo funcional eucarionte (BMC2000-0439)	Ministerio de Ciencia y Tecnología (Nacional)
01/10/1997	31/07/2000	Responsable	EUROPEAN NETWORK FOR THE FUNCTIONAL ANALYSIS OF YEAST GENES DISCOVERED BY SYSTEMATIC DNA SEGUENCING. PHASE 2 (BIO4-CT97-2294)
01/12/1995	31/10/1998	Responsable	EUROPEAN NETWORK FOR THE FUNCTIONAL ANALYSIS OF YEAST GENES DISCOVERED BY SYSTEMATIC DNA SEQUENCING. PHASE 1 EUROFAN (BIO4-CT95-0080)

Contratos

Fecha de inicio	Fecha de fin	Rol	Denominación	Agencia financiadora
01/09/2017	31/08/2018	Responsable	Exploring the Molecular Mechanism of Lurbinectedin as an Antitumoral Target in BRCA2-/-HUMAN CELL LINES (3129/0721)	PharmaMar, S.A. (Desconocido)
29/12/2014	28/12/2015	Investigador/a	Saccharomyces cerevisiae recombinant strains for dodecanol production. (2399/0747)	Abengoa Bioenergía Nuevas Tecnologías (Desconocido)
01/06/2014	31/05/2015	Responsable	Modificación Genética de microorganismos para producción de Biofuel (2287/0721)	ABENGOA RESEARCH S.L. (Desconocido)
01/05/2014	30/04/2017	Responsable	Mechanism of action of Yondelis as an R-loop-mediated genome instability inducer (2213/0721)	Pharma Mar, S.A. (Desconocido)

Ayudas

Fecha de inicio	Fecha de fin	Rol	Denominación	Agencia financiadora
01/01/2023	31/12/2025	Responsable	Centro Andaluz de Biología Molecular y Medicina Regenerativa (QUAL21 007 USE)	Junta de Andalucía (Consejería de Transformación Económica, Industria, Conocimiento y Universidades) (Autonómico)
01/07/2011	30/06/2013	Responsable	Mecanismos de recombinación e inestabilidad genómica (BFU2011-14518-E)	Ministerio de Ciencia e Innovación (Nacional)
01/12/2007	30/11/2010	Responsable	Vigilancia del ARN nuclear en la expresión génica (BFU2007-28647-E)	Ministerio de Educación y Ciencia (Nacional)
24/05/2004	24/05/2005	Responsable	European Research Conference on Gene Transcription in Yeast (BIO2002-12861-E)	Ministerio de Educación y Ciencia (Nacional)

Redes de Investigación

Fecha de inicio	Fecha de fin	Rol	Denominación	Agencia financiadora
01/06/2023	31/05/2025	Responsable	Inestabilidad Genómica (RED2022-134164-T)	Ministerio de Ciencia e Innovación (Nacional)
01/01/2020	30/10/2022	Responsable	Inestabilidad Genómica (RED2018-102372-T)	Ministerio de Ciencia, Innovación y Universidades (Nacional)
01/07/2017	31/12/2019	Responsable	Inestabilidad Genomica (BFU2016-81796-REDC)	Ministerio de Economía y Competitividad (Nacional)
01/12/2014	30/11/2016	Responsable	Inestabilidad Genómica (BFU2014-51672-REDC)	Ministerio de Economía y Competitividad (Nacional)

Infraestructura

Fecha de inicio	Fecha de fin	Rol	Denominación	Agencia financiadora
28/12/2020	28/12/2022	Responsable	Renovación de equipamiento científico en biología molecular y celular de CABIMER (IE19_101_USE)	Junta de Andalucía - Consejería de Transformación Económica, Industria, Conocimiento y Universidades (Autonómico)
01/01/2019	31/12/2021	Responsable	Equipo de secuenciación masiva para la Unidad de Genómica de CABIMER (EQC2019-005817-P)	Ministerio de Ciencia, Innovación y Universidades - Agencia Estatal de Investigación (Nacional)
01/06/2018	31/03/2022	Responsable	Mejora de infraestructura científica y actividades de transferencia y difusión de CABIMER para la adquisición del sello Maria Maeztu (SOMM17/6112/USE)	Junta de Andalucía - Consejería de Conocimiento, Investigación y Universidad (Europeo)
01/01/2018	31/03/2021	Responsable	Equipamiento para Biología Computacional y Genómica de CABIMER (EQC2018-004672-P)	Ministerio de Ciencia, Innovación y Universidades - Agencia Estatal de Investigación (Nacional)
01/01/2016	30/06/2018	Responsable	Secuenciador masivo de ácidos nucléicos para servicio de genómica (UNSE15-CE-2856)	Ministerio de Economía y Competitividad (Europeo)
01/01/2010	31/12/2012	Responsable	Actualización y ampliación de la unidad de genómica del Cabimer. Universidad de Sevilla (UNSE10-1E-433)	Ministerio de Ciencia e Innovación (Europeo)

El investigador no tiene ningún resultado de investigación asociado