CABIMER excelencia - Prisma - Unidad de Bibliometría

Centro Andaluz de Biología Molecular y Medicina Regenerativa_Excelencia (CABIMER excelencia)

Tipo de colectivo: Unidad de excelencia
Ámbito: US
Instituciones: Universidad de Sevilla
Fecha de creación: 02/07/2020
URL: https://www.cabimer.es/web3/

Investiga en

Nombre Rol
Aguilera López, Andrés Responsable
Acedo Rubio, Cristina Miembro ordinario
Areal Quecuty, Victoria Miembro ordinario
Barroso Ceballos, Sonia Ines Miembro ordinario
Bustamante Sequeiros, Mar Miembro ordinario
Castellano Pozo, Maikel Miembro ordinario
Chacon Rodriguez, Mariola Miembro ordinario
Dominguez Calvo, Andres Miembro ordinario
Dominguez Perez, Maria Del Carmen Miembro ordinario
Gaillard, Hélène Miembro ordinario
Garcia Garcia, Raquel Miembro ordinario
Garcia Muse, Tatiana Beatriz Miembro ordinario
Garcia Rodriguez, Nestor Miembro ordinario
García Rondón, Ana Beatriz Miembro ordinario
García Rubio, María Luisa Miembro ordinario
Gomez Gonzalez, Belen Miembro ordinario
González Arzola, Katiuska Miembro ordinario
Gonzalez Prieto, Roman Miembro ordinario
Herrera Moyano, Emilia Miembro ordinario
Huertas Sánchez, Pablo Miembro ordinario
Jimeno Gonzalez, Sonia Miembro ordinario
Jimeno Gonzalez, Silvia Miembro ordinario
Luna Varo, Rosa María Miembro ordinario
Martinez Fabregas, Jonathan Miembro ordinario
Martinez Muñoz, Laura Miembro ordinario
Megias Fernandez, Clara Miembro ordinario
Millan Zambrano, Gonzalo Miembro ordinario
Nuñez Martin, Ivan Miembro ordinario
Ortiz Bazan, M. Angeles Miembro ordinario
Peña Gomez, Maria Jose Miembro ordinario
Pozo Pérez, David Miembro ordinario
Prados Carvajal, Maria Del Rosario Miembro ordinario
Priego Moreno, Sara Miembro ordinario
Romero Balestra, Fernando Miembro ordinario
Roodveldt, Cintia Miembro ordinario
Silvera Carrasco, Lucia Miembro ordinario
Valle Rosado, Ivan Miembro ordinario
Wellinger, Ralf-Erik Miembro ordinario
Tipo Año Título Fuente
Capítulo2024 Análisis comparativo del efecto de la aplicación de distintas técnicas de innovación docente en las asignaturas del Departamento de Genética de la Universidad de Sevilla Enseñanza e innovación educativa en el ámbito universitario
Capítulo2024 Aula invertida como innovación docente en el grado de Odontología de la Universidad de Sevilla Enseñanza e innovación educativa en el ámbito universitario
Published Erratum2024 Author Correction: dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe. NATURE COMMUNICATIONS
Artículo2024 BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis NATURE COMMUNICATIONS
Artículo2024 Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions BRITISH JOURNAL OF CANCER
Artículo2024 Distinct Gastrointestinal and Reproductive Microbial Patterns in Female Holobiont of Infertility MICROORGANISMS
Artículo2024 dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe. NATURE COMMUNICATIONS
Editorial2024 Editorial: SARS-CoV-2 in neurodegenerative diseases FRONTIERS IN NEUROSCIENCE
Artículo2024 EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells. NUCLEIC ACIDS RESEARCH
Artículo2024 Expression of human RECQL5 in Saccharomyces cerevisiae causes transcription defects and transcription-associated genome instability MOLECULAR GENETICS AND GENOMICS
Artículo2024 Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS. SCIENCE ADVANCES
Capítulo2024 Innovación docente en bioquímica: Nuevas perspectivas en el desarrollo de PODCASTS como una herramienta de aprendizaje en la Universidad de Sevilla Enseñanza e innovación educativa en el ámbito universitario
Capítulo2024 Innovación docente en bioquímica: nuevas perspectivas en el desarrollo de podcasts como una herramienta de aprendizaje en la Universidad de Sevilla Enseñanza e innovación educativa en el ámbito universitario
Capítulo2024 Innovación en la enseñanza de las prácticas de laboratorio: métodos y estrategias docentes para actuar sobre el currículum oculto Enseñanza e innovación educativa en el ámbito universitario
Capítulo2024 Nuevas estrategias docentes para promover la participación del alumnado en las discusiones de los seminarios de biología molecular en organismos modelo Enseñanza e innovación educativa en el ámbito universitario
Artículo2024 Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability. PLOS GENETICS
Revisión2024 Prevalence of apical periodontitis and non-retention of root-filled teeth in hypertensive patients: Systematic review and meta-analysis INTERNATIONAL ENDODONTIC JOURNAL
Artículo2024 Rat1 promotes premature transcription termination at R-loops NUCLEIC ACIDS RESEARCH
Artículo2024 RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity. GENES & DEVELOPMENT
Artículo2024 RNF212B E3 ligase is essential for crossover designation and maturation during male and female meiosis in the mouse PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2024 SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability CELL REPORTS
Artículo2024 Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy NATURE COMMUNICATIONS
Artículo2024 The immune system in Parkinson's disease: what we know so far. BRAIN
Revisión2024 The nucleolus: Coordinating stress response and genomic stability BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Artículo2024 UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168 NATURE COMMUNICATIONS
Artículo2024 VEGF expression disparities in brainstem motor neurons of the SOD1G93A ALS model: Correlations with neuronal vulnerability Neurotherapeutics
Artículo2023 A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2023 A novel biocompatible polymer derived from D-mannitol used as a vector in the field of genetic engineering of eukaryotic cells COLLOIDS AND SURFACES B-BIOINTERFACES
Artículo2023 Actin nucleators safeguard replication forks by limiting nascent strand degradation NUCLEIC ACIDS RESEARCH
Corrección2023 Author correction: Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells. NATURE COMMUNICATIONS
Artículo2023 Break-induced RNA-DNA hybrids (BIRDHs) in homologous recombination: friend or foe? EMBO REPORTS
Artículo2023 CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2023 Cell consequences of loss of function of the epigenetic factor EHMT1. CELLULAR SIGNALLING
Artículo2023 Centriolar subdistal appendages promote double-strand break repair through homologous recombination. EMBO REPORTS
Artículo2023 Chromosomal Instability in Genome Evolution: From Cancer to Macroevolution Biology
Artículo2023 DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops. CELL REPORTS
Artículo2023 DICER ribonuclease removes harmful R-loops MOLECULAR CELL
Revisión2023 Does Diabetes Increase the Frequency of Root-Filled teeth: Systematic Review and Meta-Analysis of Observational Studies Journal of Clinical and Experimental Dentistry
Artículo2023 Hyperextended telomeres promote formation of C-circle DNA in telomerase positive human cells. JOURNAL OF BIOLOGICAL CHEMISTRY
Capítulo2023 Innovación docente en las prácticas de laboratorio de genética: clase invertida y pensamiento crítico Educación, tecnología, innovación y transferencia del conocimiento
Artículo2023 MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2023 Mitochondrial Factors in the Cell Nucleus. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2023 N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer ONCOGENE
Artículo2023 PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection. GENES & DEVELOPMENT
Revisión2023 Prevalence of root canal treatments among diabetic patients: systematic review and meta-analysis APPLIED SCIENCES-BASEL
Artículo2023 Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos GENETICS
Artículo2023 Spontaneous deamination of cytosine to uracil is biased to the non-transcribed DNA strand in yeast DNA REPAIR
Artículo2023 SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome SCIENCE ADVANCES
Artículo2023 The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts NATURE COMMUNICATIONS
Artículo2023 The kleisin subunit controls the function of C. elegans meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1. eLife
Artículo2023 The lncRNA LETS1 promotes TGF-beta-induced EMT and cancer cell migration by transcriptionally activating a TbetaR1-stabilizing mechanism. SCIENCE SIGNALING
Artículo2023 TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX-deficient cells iScience
Artículo2023 Ubiquitinome profiling reveals inVivo UBE2D3 targets and implicates UBE2D3 in protein quality control. MOLECULAR & CELLULAR PROTEOMICS
Artículo2022 A LexAop > UAS > QUAS trimeric plasmid to generate inducible and interconvertible Drosophila overexpression transgenes Scientific reports
Editorial2022 A new challenge for data analytics: transposons. BIODATA MINING
Artículo2022 A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability. GENETICS
Artículo2022 Adaptive response of Saccharomyces hosts to Totiviridae L-A dsRNA viruses is achieved through intrinsically balanced action of targeted transcription factors JOURNAL OF FUNGI
Artículo2022 Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2022 Antibiotics prescription habits of Spanish endodontists: Impact of the ESE awareness campaign and position statement Journal of Clinical and Experimental Dentistry
Resumen congreso2022 Chromatin modifications upon transcription-dependent or independent replication stress ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Data Paper2022 Data of transcriptional effects of the merbarone-mediated inhibition of TOP2 DATA IN BRIEF
Capítulo2022 Detection of R-Loops by In Vivo and In Vitro Cytosine Deamination in Saccharomyces cerevisiae R-Loops: methods and protocols
Editorial2022 Editorial: Nanoparticle-mediated signaling rewiring and reprogramming of immune responses FRONTIERS IN IMMUNOLOGY
Editorial2022 Editorial: The Role of RNA in Genome Stability: To Wreck or Repair? FRONTIERS IN MOLECULAR BIOSCIENCES
Artículo2022 Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells. NATURE COMMUNICATIONS
Artículo2022 FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine CELL DEATH & DISEASE
Artículo2022 Fluorescent calixarene-schiff as a nanovehicle with biomedical purposes Chemosensors
Capítulo2022 Genome-Wide Analysis of DNA-RNA Hybrids in Yeast by DRIPc-Seq and DRIP-Seq R-Loops: methods and protocols
Revisión2022 Histone post-translational modifications — cause and consequence of genome function NATURE REVIEWS GENETICS
Artículo2022 IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein. Science immunology
Artículo2022 Insights in Post-Translational Modifications: Ubiquitin and SUMO INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2022 Lysosomes: multifunctional compartments ruled by a complex regulatory network. FEBS OPEN BIO
Artículo2022 Manganese is a physiologically relevant TORC1 activator in yeast and mammals. eLife
Artículo2022 Manganese stress tolerance depends on Yap1 and stress-activated MAP kinases INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Resumen congreso2022 Mechanisms for RNA-mediated genome instability ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Artículo2022 MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells CELL REPORTS
Resumen congreso2022 NPM1 phase transition modulation via post-translational modifications and heterotypic interactions FEBS OPEN BIO
Artículo2022 Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation. NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo2022 PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ Computational and Structural Biotechnology Journal
Artículo2022 Prevalence of dens invaginatus assessed by CBCT: systematic review and meta-analysis Journal of Clinical and Experimental Dentistry
Revisión2022 Preventing and overcoming resistance to parp inhibitors: a focus on the clinical landscape CANCERS
Artículo2022 Proline-specific aminopeptidase P prevents replication-associated genome instability PLOS GENETICS
Libro2022 R-Loops: methods and protocols R-Loops: methods and protocols
Resumen congreso2022 Respiratory Cytochrome c: a Master Pleiotropic Cell Regulator BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Capítulo2022 RNase H1 Hybrid-Binding Domain-Based Tools for Cellular Biology Studies of DNA–RNA Hybrids in Mammalian Cells R-Loops: methods and protocols
Artículo2022 Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model GUT
Artículo2022 THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1 NUCLEIC ACIDS RESEARCH
Artículo2022 Titanium Surface Characteristics Induce the Specific Reprogramming of Toll-like Receptor Signaling in Macrophages INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2022 Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability CELL REPORTS
Capítulo2022 Un ciclo de mejora docente para estudiar Evolución Molecular Ciclos de mejora en el aula. Año 2021: experiencias de innovación docente de la Universidad de Sevilla
Artículo2022 WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage. NATURE COMMUNICATIONS
Artículo2022 XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair NATURE COMMUNICATIONS
Artículo2022 XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2′-Deoxycytidine and 5-Hydroxymethyl-2′-Deoxyuridine INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2021 A CDK-regulated chromatin segregase promoting chromosome replication. NATURE COMMUNICATIONS
Artículo2021 A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair NATURE COMMUNICATIONS
Artículo2021 A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae NUCLEIC ACIDS RESEARCH
Revisión2021 A new interaction between BRCA2 and DDX5 promotes the repair of DNA breaks at transcribed chromatin MOLECULAR & CELLULAR ONCOLOGY
Artículo2021 A proteomics study identifying interactors of the FSHD2 gene product SMCHD1 reveals RUVBL1-dependent DUX4 repression Scientific reports
Artículo2021 A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells NATURE COMMUNICATIONS
Artículo2021 ADAR-mediated RNA editing of DNA: RNA hybrids is required for DNA double strand break repair. NATURE COMMUNICATIONS
Capítulo2021 Analysis of repair of replication-born double-strand breaks by sister chromatid recombination in yeast The DNA replication-repair interface
Artículo2021 Antibiotics prescription by Spanish general practitioners in primary dental care Antibiotics
Artículo2021 Biomaterials in periapical regeneration after microsurgical endodontics: a narrative review Journal of Clinical and Experimental Dentistry
Artículo2021 BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair EMBO JOURNAL
Artículo2021 Cationic single-chained surfactants with a functional group at the end of the hydrophobic tail DNA compacting efficiency. PHARMACEUTICS
Nota2021 Cell-based drug delivery harnesses inflammatory and autoimmune responses in neurodegeneration JOURNAL OF MOLECULAR MEDICINE-JMM
Artículo2021 CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes NATURE COMMUNICATIONS
Artículo2021 Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses eLife
Corrección2021 Corrigendum: UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide. GENES & DEVELOPMENT
Artículo2021 CtIP -mediated alternative mRNA splicing finetunes the DNA damage response RNA-A PUBLICATION OF THE RNA SOCIETY
Capítulo2021 Detection of DNA Double-Strand Breaks by γ-H2AX Immunodetection Homologous recombination: methods and protocols
Artículo2021 Detection of DSBs in C. elegans Meiosis Methods in molecular biology
Artículo2021 Distinct responses of human peripheral blood cells to different misfolded protein oligomers IMMUNOLOGY
Artículo2021 DNA-RNA hybrids at DSBs interfere with repair by homologous recombination. eLife
Artículo2021 ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation NATURE CELL BIOLOGY
Artículo2021 ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients JOURNAL OF EXPERIMENTAL MEDICINE
Artículo2021 Evaluation of undergraduate Endodontic teaching in dental schools within Spain INTERNATIONAL ENDODONTIC JOURNAL
Artículo2021 Fluctuations in AKT and PTEN activity are linked by the E3 ubiquitin ligase cCBL Cells
Artículo2021 Global non-covalent SUMO interaction networks reveal SUMO-dependent stabilization of the non-homologous end joining complex CELL REPORTS
Artículo2021 Harmful R-loops are prevented via different cell cycle-specific mechanisms NATURE COMMUNICATIONS
Revisión2021 Heterogeneity of DNA damage incidence and repair in different chromatin contexts DNA REPAIR
Editorial2021 Homologous recombination methods and protocols preface Homologous recombination: methods and protocols
Libro2021 Homologous recombination: methods and protocols Homologous recombination: methods and protocols
Artículo2021 Human prefoldin modulates co-transcriptional pre-mRNA splicing. NUCLEIC ACIDS RESEARCH
Artículo2021 Identifying cytokine signaling signatures in primary human Th-1 cells by phospho-proteomics analysis. STAR Protocols
Revisión2021 Immune signaling kinases in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Capítulo2021 In Vivo Binding of Recombination Proteins to Non-DSB DNA Lesions and to Replication Forks Homologous recombination: methods and protocols
Artículo2021 Influence of coronal preflaring on the accuracy of electronic working length determination: systematic review and meta-analysis JOURNAL OF CLINICAL MEDICINE
Artículo2021 Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome C REDOX BIOLOGY
Artículo2021 Metallo-liposomes derived from the [ru(Bpy)3]2+ complex as nanocarriers of therapeutic agents Chemosensors
Artículo2021 Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication MOLECULAR CELL
Artículo2021 Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus. FEBS OPEN BIO
Resumen congreso2021 Molecular basis for the DNA damage-induced interaction between cytochrome c and the histone chaperone SET/TAF-I beta FEBS OPEN BIO
Artículo2021 MRGBP, a member of the NuA4 complex, inhibits DNA double strand break repair FEBS OPEN BIO
Artículo2021 Multivalent calixarene-based liposomes as platforms for gene and drug delivery. PHARMACEUTICS
Artículo2021 Non-recombinogenic roles for Rad52 in translesion synthesis during DNA damage tolerance EMBO REPORTS
Revisión2021 Origin matters: spontaneous DNA–RNA hybrids do not form in trans as a source of genome instability CURRENT GENETICS
Artículo2021 Physical interactions between MCM and Rad51 facilitate replication fork lesion bypass and ssDNA gap filling by non-recombinogenic functions CELL REPORTS
Editorial2021 Preface Methods in molecular biology
Artículo2021 Prevalence of endodontic infection in patients with Crohn´s disease and ulcerative colitis Medicina oral, patología oral y cirugía bucal
Artículo2021 Prevalencia de la infección oral de origen endodóncico en pacientes con enfermedad de Crohn y Colitis Ulcerosa Medicina oral, patología oral y cirugía bucal
Artículo2021 Properties of polyplexes formed between a cationic polymer derived from l-arabinitol and nucleic acids NEW JOURNAL OF CHEMISTRY
Artículo2021 Proposed mechanism for regulation of H2O2-induced programmed cell death in plants by binding of cytochrome c to 14-3-3 proteins PLANT JOURNAL
Artículo2021 R-loop-mediated ssDNA breaks accumulate following short-term exposure to the HDAC inhibitor romidepsin. MOLECULAR CANCER RESEARCH
Artículo2021 Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Artículo2021 The effect of atypical nucleic acids structures in DNA double strand break repair: a tale of R-loops and G-quadruplexes FRONTIERS IN GENETICS
Revisión2021 The emerging role of RNA modifications in DNA double-strand break repair FRONTIERS IN MOLECULAR BIOSCIENCES
Artículo2021 The human nucleoporin Tpr protects cells from RNA-mediated replication stress. NATURE COMMUNICATIONS
Artículo2021 The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity THERANOSTICS
Artículo2021 The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2021 The role of chromatin at transcription-replication conflicts as a genome safeguard. BIOCHEMICAL SOCIETY TRANSACTIONS
Capítulo2021 The sister-chromatid exchange assay in human cells Homologous recombination: methods and protocols
Artículo2021 The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription-replication conflicts NATURE GENETICS
Nota2021 The SWI/SNF complex, transcription-replication conflicts and cancer: a connection with high therapeutic potential MOLECULAR & CELLULAR ONCOLOGY
Artículo2021 THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans JOURNAL OF CELL SCIENCE
Artículo2021 Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing CELL REPORTS
Artículo2021 Trim37 prevents formation of centriolar protein assemblies by regulating centrobin eLife
Artículo2021 TRIM37: a critical orchestrator of centrosome function CELL CYCLE
Artículo2021 Use of contemporary technologies and new materials in undergraduate Endodontics teaching Journal of Clinical and Experimental Dentistry
Artículo2021 VID22 counteracts G-quadruplex-induced genome instability. NUCLEIC ACIDS RESEARCH
Artículo2021 Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining NATURE COMMUNICATIONS
Artículo2020 ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resection PLOS GENETICS
Revisión2020 Cardiovascular diseases and apical periodontitis: association not always implies causality Medicina oral, patología oral y cirugía bucal
Artículo2020 CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci CELL REPORTS
Revisión2020 Cigarette smoking and root filled teeth extraction: systematic review and meta-analysis JOURNAL OF CLINICAL MEDICINE
Artículo2020 Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGF beta-Induced Breast Cancer Metastasis CLINICAL CANCER RESEARCH
Artículo2020 Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency NATURE COMMUNICATIONS
Artículo2020 Enfermedades cardiovasculares y periodontitis apical: asociación no siempre implica causalidad Medicina oral, patología oral y cirugía bucal
Artículo2020 Exploring protein phosphorylation by combining computational approaches and biochemical methods Computational and Structural Biotechnology Journal
Artículo2020 Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner eLife
Revisión2020 Histone deacetylases facilitate the accurate repair of broken forks MOLECULAR & CELLULAR ONCOLOGY
Artículo2020 Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage MICROBIAL CELL
Artículo2020 Homologous recombination and Mus81 promote replication completion in response to replication fork blockage EMBO REPORTS
Revisión2020 Lipids and their (un)known effects on ER-associated protein degradation (ERAD) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Revisión2020 Looping the (R) Loop in DSB Repair via RNA Methylation MOLECULAR CELL
Revisión2020 Mechanisms of eukaryotic replisome disassembly BIOCHEMICAL SOCIETY TRANSACTIONS
Artículo2020 Metallo-liposomes of ruthenium used as promising vectors of genetic material PHARMACEUTICS
Artículo2020 Methylation of the central transcriptional regulator KLF4 by PRMT5 is required for DNA end resection and recombination DNA REPAIR
Artículo2020 Modified level of miR-376a is associated with Parkinson's disease JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Resumen congreso2020 Obesity-Induced Astrogliosis Is Regulated by the Diabesity Factor HMG20A DIABETES
Artículo2020 PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks NUCLEIC ACIDS RESEARCH
Artículo2020 Preparation of a radiobiology beam line at the 18 MeV proton cyclotron facility at CNA PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
Artículo2020 Processing of DNA Polymerase-Blocking Lesions during Genome Replication Is Spatially and Temporally Segregated from Replication Forks MOLECULAR CELL
Artículo2020 Self-aggregation in aqueous solution of amphiphilic cationic calix[4]arenes. Potential use as vectors and nanocarriers JOURNAL OF MOLECULAR LIQUIDS
Revisión2020 Smoking and radiolucent periapical lesions in root filled teeth: systematic review and meta-analysis JOURNAL OF CLINICAL MEDICINE
Revisión2020 Spontaneous DNA-RNA hybrids: differential impacts throughout the cell cycle CELL CYCLE
Artículo2020 Structure-property relationships of D-mannitol-based cationic poly(amide triazoles) and their self-assembling complexes with DNA EUROPEAN POLYMER JOURNAL
Revisión2020 Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox FRONTIERS IN MOLECULAR BIOSCIENCES
Artículo2020 Surveillance of cohesin-supported chromosome structure controls meiotic progression NATURE COMMUNICATIONS
Artículo2020 TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loopmediated DNA damage PLOS GENETICS
Artículo2020 The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II NATURE COMMUNICATIONS
Corrección2020 The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II (vol 11, 2104, 2020) NATURE COMMUNICATIONS
Artículo2020 TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres eLife
Artículo2020 UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide GENES & DEVELOPMENT
Nota2019 A conversation with Andrés Aguilera COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES
Capítulo2019 A dual system to manipulate protein levels for DNA replication- and cell cycle-related studies UBIQUITIN-DEPENDENT PROTEIN DEGRADATION
Artículo2019 A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs CELL REPORTS
Capítulo2019 Controlling the balance between chromosome break repair pathways DNA REPAIR
Artículo2019 Depletion of the MFAP1/SPP381 splicing factor causes R-loop-independent genome instability CELL REPORTS
Artículo2019 Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers ACS CHEMICAL NEUROSCIENCE
Resumen congreso2019 DNA damage triggers the interaction of cytochrome c with the disordered region of ANP32B FEBS OPEN BIO
Artículo2019 Elongation factor TFIIS prevents transcription stress and R-loop accumulation to maintain genome stability MOLECULAR CELL
Artículo2019 EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks NATURE COMMUNICATIONS
Artículo2019 Genome architecture and stability in the Saccharomyces cerevisiae knockout collection NATURE
Revisión2019 Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways MICROBIAL CELL
Artículo2019 Image processing protocol for the analysis of the diffusion and cluster size of membrane receptors by fluorescence microscopy JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
Artículo2019 Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2019 Kinetics of cytokine receptor trafficking determine signaling and functional selectivity eLife
Letter2019 Mind the nick CELL CYCLE
Artículo2019 Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity LIFE SCIENCE ALLIANCE
Resumen congreso2019 Molecular basis for acute hypoxia-related diseases: Understanding the cross-talk between cytochrome c and hypoxia-induced protein HIGD1A in the mitochondria FEBS OPEN BIO
Revisión2019 New moonlighting functions of mitochondrial cytochrome c in the cytoplasm and nucleus FEBS LETTERS
Artículo2019 Pif1-family helicases support fork convergence during DNA replication termination in eukaryotes MOLECULAR CELL
Artículo2019 Preparation and characterization of metallomicelles of Ru(II). Cytotoxic activity and use as vector COLLOIDS AND SURFACES B-BIOINTERFACES
Revisión2019 R Loops: From Physiological to Pathological Roles CELL
Artículo2019 R-Loops as Promoters of Antisense Transcription MOLECULAR CELL
Artículo2019 Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion NATURE COMMUNICATIONS
Artículo2019 Rpd3l contributes to the DNA damage sensitivity of saccharomyces cerevisiae checkpoint mutants GENETICS
Artículo2019 Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks CELL REPORTS
Artículo2019 Surface modulation of single-walled carbon nanotubes for selective bacterial cell agglutination INTERNATIONAL JOURNAL OF NANOMEDICINE
Artículo2019 Synthesis and Characterization of Elongated-Shaped Silver Nanoparticles as a Biocompatible Anisotropic SERS Probe for Intracellular Imaging: Theoretical Modeling and Experimental Verification NANOMATERIALS
Artículo2019 The antitumor drugs trabectedin and lurbinectedin induce transcription-dependent replication stress and genome instability MOLECULAR CANCER RESEARCH
Artículo2019 The DNA damage response acts as a safeguard against harmful DNA-RNA hybrids of different origins EMBO REPORTS
Artículo2019 The Nup84 complex coordinates the DNA damage response to warrant genome integrity NUCLEIC ACIDS RESEARCH
Revisión2019 The role of RNA and RNA-related proteins in the regulation of DNA double strand break repair pathway choice DNA REPAIR
Revisión2019 The THO complex as a paradigm for the prevention of cotranscriptional R-loops COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES
Revisión2019 Transcription-mediated replication hindrance: A major driver of genome instability GENES & DEVELOPMENT
Capítulo2019 TULIP: Targets of Ubiquitin Ligases Identified by Proteomics SUMOylation and Ubiquitination: Current and Emerging Concepts
Artículo2019 TULIP2: An Improved Method for the Identification of Ubiquitin E3-Specific Targets FRONTIERS IN CHEMISTRY
Artículo2019 UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors CELL
Artículo2019 USP7: combining tools towards selectivity CHEMICAL COMMUNICATIONS
Revisión2019 What causes an RNA-DNA hybrid to compromise genome integrity? DNA REPAIR
Artículo2018 Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study PLOS ONE
Editorial2018 Chromosome instability: From molecular mechanisms to disease DNA REPAIR
Artículo2018 Coordinated activity of Y family TLS polymerases and EXO1 protects non-S phase cells from UV-induced cytotoxic lesions MOLECULAR CELL
Corrección2018 Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions (vol 70, pg 34, 2018) MOLECULAR CELL
Ponencia2018 Cytochrome c is revealed as a double activator of apoptosis through its interaction with 14-3-3 epsilon FEBS OPEN BIO
Artículo2018 Cytochrome c speeds up caspase cascade activation by blocking 14-3-3 epsilon-dependent Apaf-1 inhibition CELL DEATH & DISEASE
Artículo2018 Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1 NATURE COMMUNICATIONS
Capítulo2018 Detection of DNA-RNA hybrids in vivo GENOME INSTABILITY: METHODS AND PROTOCOLS
Artículo2018 Epigenetic features of human telomeres NUCLEIC ACIDS RESEARCH
Corrección2018 Erratum: Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function (Molecular Cell (2018) 70(1) (106–119.e10), (S1097276518301795) (10.1016/j.molcel.2018.02.034)) MOLECULAR CELL
Artículo2018 Gene gating at nuclear pores prevents the formation of R loops MOLECULAR & CELLULAR ONCOLOGY
Artículo2018 Genotoxicity of tetrahydrofolic acid to hematopoietic stem and progenitor cells CELL DEATH AND DIFFERENTIATION
Artículo2018 Guidelines and recomendations on yeast cell death nomenclature MICROBIAL CELL
Artículo2018 Human mitochondrial degradosome prevents harmful mitochondria! R loops and mitochondrial genome instability PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2018 Immunization with alpha-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model GLIA
Artículo2018 Importance of hydrophobic interactions in the single-chained cationic surfactant-DNA complexation JOURNAL OF COLLOID AND INTERFACE SCIENCE
Artículo2018 LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus NATURE COMMUNICATIONS
Artículo2018 Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis NATURE COMMUNICATIONS
Revisión2018 Mapping Determinants of Cytokine Signaling via Protein Engineering FRONTIERS IN IMMUNOLOGY
Artículo2018 Multiple roles of the splicing complex SF3B in DNA end resection and homologous recombination DNA REPAIR
Artículo2018 Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts NATURE COMMUNICATIONS
Artículo2018 Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair NUCLEIC ACIDS RESEARCH
Artículo2018 Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2018 PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells IMMUNITY
Artículo2018 Phosphorylation of histone H4T80 triggers DNA damage checkpoint recovery MOLECULAR CELL
Revisión2018 Remodeling our concept of chemokine receptor function: From monomers to oligomers Journal of leukocyte biology
Artículo2018 Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function MOLECULAR CELL
Capítulo2018 Single molecule analysis of resection tracks GENOME INSTABILITY: METHODS AND PROTOCOLS
Artículo2018 Spatial separation between replisome- and template-induced replication stress signaling EMBO JOURNAL
Artículo2018 The dual role of the centrosome in organizing the microtubule network in interphase EMBO REPORTS
Artículo2018 The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures CELL REPORTS
Corrección2018 The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures (vol 24, 3262, 2018) CELL REPORTS
Artículo2018 The helicase Pif1 functions in the template switching pathway of DNA damage bypass NUCLEIC ACIDS RESEARCH
Artículo2018 The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair MOLECULAR CELL
Artículo2018 Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery OBESITY SURGERY
Artículo2018 Yra1-bound RNA-DNA hybrids cause orientation-independent transcription-replication collisions and telomere instability GENES & DEVELOPMENT
Artículo2018 ZYG-1 promotes limited centriole amplification in the C. elegans seam lineage DEVELOPMENTAL BIOLOGY
Artículo2017 A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination PLOS GENETICS
Artículo2017 Cannabinoid derivatives exert a potent anti-myeloma activity both in vitro and in vivo INTERNATIONAL JOURNAL OF CANCER
Artículo2017 Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme NATURE COMMUNICATIONS
Nota2017 Commentary: Immunochemical markers of the amyloid cascade in the hippocampus in motor neuron diseases FRONTIERS IN NEUROLOGY
Artículo2017 CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells STEM CELL REPORTS
Artículo2017 CUL-2(LRR-1) and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis NATURE CELL BIOLOGY
Artículo2017 Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells DNA REPAIR
Corrección2017 Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange (vol 32, 1592, 2012) MOLECULAR AND CELLULAR BIOLOGY
Artículo2017 DNA end resection requires constitutive sumoylation of CtIP by CBX4 NATURE COMMUNICATIONS
Revisión2017 DNA-RNA hybrids: the risks of DNA breakage during transcription NATURE STRUCTURAL & MOLECULAR BIOLOGY
Editorial2017 Editorial: Molecular Chaperones and Neurodegeneration FRONTIERS IN NEUROSCIENCE
Artículo2017 Epigenetic Mechanisms of Gene Regulation in Amyotrophic Lateral Sclerosis Advances in experimental medicine and biology
Artículo2017 Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4 FASEB JOURNAL
Ponencia2017 Expanding the mitochondrial links to the DNA damage response FEBS JOURNAL
Artículo2017 Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia FASEB JOURNAL
Revisión2017 Histone availability as a strategy to control gene expression RNA BIOLOGY
Artículo2017 Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c NUCLEIC ACIDS RESEARCH
Artículo2017 Histone Mutants Separate R Loop Formation from Genome Instability Induction MOLECULAR CELL
Ponencia2017 Human SET/TAF-I beta and plant NRP1 are similarly inhibited by cytochrome c in the cell nucleus EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Artículo2017 Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability EMBO JOURNAL
Artículo2017 La plasticidad genómica, un arma de doble filo MEMORIAS DE LA REAL ACADEMIA SEVILLANA DE CIENCIAS
Artículo2017 Live cell X-ray imaging of autophagic vacuoles formation and chromatin dynamics in fission yeast Scientific reports
Artículo2017 Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism NATURE
Revisión2017 Non-Canonical Replication Initiation: You're Fired! GENES
Ponencia2017 Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair FEBS JOURNAL
Artículo2017 P-Sulfocalix[6]arene as Nanocarrier for Controlled Delivery of Doxorubicin CHEMISTRY-AN ASIAN JOURNAL
Resumen congreso2017 PD-1 through Asparaginyl Endopeptidase Regulates Foxp3 Stability in Induced Regulatory T Cells BLOOD
Ponencia2017 Phosphorylation of cytochrome c: Structure, dynamics and functions EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Artículo2017 Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Ponencia2017 Post-translation tyrosine phosphorylation switches cytochrome c dynamics. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
Artículo2017 Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control NATURE
Artículo2017 Repair of UV-induced DNA lesions in natural Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction NUCLEIC ACIDS RESEARCH
Artículo2017 RNA binding by histone methyltransferases Set1 and Set2 MOLECULAR AND CELLULAR BIOLOGY
Ponencia2017 Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Artículo2017 Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2017 Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning Epigenetics & Chromatin
Artículo2017 Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer ONCOTARGET
Artículo2017 The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage BLOOD
Artículo2017 The chaperonin CCT inhibits assembly of alpha-synuclein amyloid fibrils by a specific, conformation-dependent interaction Scientific reports
Revisión2017 The need to regulate replication fork speed SCIENCE
Artículo2017 The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation NUCLEIC ACIDS RESEARCH
Revisión2017 The Role of Replication-Associated Repair Factors on R-Loops GENES
Artículo2017 The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage PLOS GENETICS
Artículo2017 The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery NATURE COMMUNICATIONS
Capítulo2017 Update on nanoparticle-mediated immune mechanisms for dendritic cell-based targeted immunity and cancer NANOMEDICINE IN CANCER
Artículo2017 Use of lentiviral particles as a cell membrane-based mFasL delivery system for in vivo treatment of inflammatory arthritis FRONTIERS IN IMMUNOLOGY
Resumen congreso2017 Xenografts of blasts originating from patients with acute myeloblastic leukemia in immunosuppressed mice: clinical implications potentials HAEMATOLOGICA
Artículo2016 A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection NATURE COMMUNICATIONS
Artículo2016 A new colorimetric assay for antioxidant capacity and photostability COLORATION TECHNOLOGY
Artículo2016 Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the alpha-synuclein-elicited immune response FASEB JOURNAL
Capítulo2016 Chemokine detection using receptors immobilized on an SPR sensor surface CHEMOKINES
Revisión2016 Chromatin structure and pre-mRNA processing work together TRANSCRIPTION-AUSTIN
Artículo2016 Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes eLife
Artículo2016 Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase MOLECULAR CELL
Capítulo2016 Cytochrome c-Based Signalosome REDOX PROTEINS IN SUPERCOMPLEXES AND SIGNALOSOMES
Artículo2016 Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere Shortening PLOS GENETICS
Artículo2016 FANCD2 Facilitates Replication through Common Fragile Sites MOLECULAR CELL
Revisión2016 Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress FRONTIERS IN GENETICS
Artículo2016 High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast PLOS GENETICS
Revisión2016 Iron oxide nanoparticles as magnetic relaxation switching (MRSw) sensors: Current applications in nanomedicine NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
Artículo2016 Meiotic Nuclear Oscillations Are Necessary to Avoid Excessive Chromosome Associations CELL REPORTS
Ponencia2016 Role of Chromatin and the DNA Damage Response in RNA-Mediated Genome Instability. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Artículo2016 Roles of human POLD1 and POLD3 in genome stability Scientific reports
Artículo2016 Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion CELL DEATH & DISEASE
Revisión2016 The 'Omics' of Amyotrophic Lateral Sclerosis TRENDS IN MOLECULAR MEDICINE
Corrección2016 The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development (vol 7, e52447, 2012) PLOS ONE
Resumen congreso2016 The LRH1 Agonist BL001 Simultaneously Targets Immune and Islet Cells to Repress Type 1 Diabetes DIABETES
Artículo2016 Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2 SCIENCE SIGNALING
Revisión2016 Transcription as a Threat to Genome Integrity ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85
Revisión2016 Transcription-replication conflicts: how they occur and how they are resolved NATURE REVIEWS MOLECULAR CELL BIOLOGY
Artículo2016 Tuning of glyconanomaterial shape and size for selective bacterial cell agglutination JOURNAL OF MATERIALS CHEMISTRY B
Capítulo2016 Use of resonance energy transfer techniques for in vivo detection of chemokine receptor oligomerization Chemotaxis: methods and protocols
Artículo2016 Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium JOURNAL OF CELL SCIENCE
Ponencia2015 A Common Cytochrome c-centred Signalosome for Programmed Cell Death in Humans and Plants FASEB JOURNAL
Ponencia2015 A Common Role for Cytochrome c in Programmed Cell Death in Humans and Plants PROTEIN SCIENCE
Artículo2015 A positioned +1 nucleosome enhances promoter-proximal pausing NUCLEIC ACIDS RESEARCH
Artículo2015 A unified model for the molecular basis of Xeroderma pigmentosum - Cockayne Syndrome RARE DISEASES
Ponencia2015 Additional binding sites for cytochrome c on its redox membrane partners facilitate its turnover and sliding mechanisms within respiratory supercomplexes PROTEIN SCIENCE
Artículo2015 Betalactam antibiotics affect human dendritic cells maturation through MAPK/NF-kB systems. Role in allergic reactions to drugs TOXICOLOGY AND APPLIED PHARMACOLOGY
Artículo2015 c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4 CELL CYCLE
Artículo2015 COPII Coat Composition Is Actively Regulated by Luminal Cargo Maturation CURRENT BIOLOGY
Artículo2015 Defective histone supply causes changes in RNA polymerase II elongation rate and cotranscriptional pre-mRNA splicing PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2015 Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen MOLECULAR CELL
Artículo2015 Interdependence of the Rad50 Hook and Globular Domain Functions MOLECULAR CELL
Artículo2015 Long-circulating PEGylated manganese ferrite nanoparticles for MRI-based molecular imaging NANOSCALE
Artículo2015 Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function JOURNAL OF BIOLOGICAL CHEMISTRY
Capítulo2015 Methods to immobilize GPCR on the surface of SPR sensors G PROTEIN-COUPLED RECEPTOR SCREENING ASSAYS: METHODS AND PROTOCOLS
Artículo2015 Methods to Study Transcription-Coupled Repair in Chromatin CHROMATIN PROTOCOLS, 3RD EDITION
Artículo2015 NAR Breakthrough Article H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes NUCLEIC ACIDS RESEARCH
Artículo2015 Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice NUCLEIC ACIDS RESEARCH
Letter2015 Paternally contributed centrioles exhibit exceptional persistence in C-elegans embryos CELL RESEARCH
Ponencia2015 Phosphorylation of cytochrome c at positions 28 and 47 could affect its double role in the cell PROTEIN SCIENCE
Artículo2015 Polycomb RING1A-and RING1B-dependent histone H2A monoubiquitylation at pericentromeric regions promotes S-phase progression JOURNAL OF CELL SCIENCE
Artículo2015 Polysaccharide Colloids as Smart Vehicles in Cancer Therapy CURRENT PHARMACEUTICAL DESIGN
Artículo2015 Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes PHYSICAL REVIEW LETTERS
Revisión2015 R loops: new modulators of genome dynamics and function NATURE REVIEWS GENETICS
Ponencia2015 R-loop-mediated genome instability in histone mutants YEAST
Ponencia2015 R-loops as a source of genome instability in yeast and cancer cells YEAST
Revisión2015 Regulation of Unperturbed DNA Replication by Ubiquitylation GENES
Revisión2015 Replication stress and cancer Nature Reviews. Cancer
Artículo2015 Respiratory complexes III and IV can each bind two molecules of cytochrome c at low ionic strength FEBS LETTERS
Artículo2015 RNA polymerase II contributes to preventing transcription-mediated replication fork stalls EMBO JOURNAL
Artículo2015 Role for RNA: DNA hybrids in origin-independent replication priming in a eukaryotic system PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2015 Speed matters: How subtle changes in DNA end resection rate affect repair MOLECULAR & CELLULAR ONCOLOGY
Artículo2015 Structural basis for inhibition of the histone chaperone activity of SET/TAF-I beta by cytochrome c PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2015 Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2015 SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites EMBO REPORTS
Artículo2015 Synthesis of 1D-glyconanomaterials by a hybrid noncovalent-covalent functionalization of single wall carbon nanotubes: a study of their selective interactions with lectins and with live cells NANOSCALE
Revisión2015 T cell migration in rheumatoid arthritis FRONTIERS IN IMMUNOLOGY
Revisión2015 Termination of DNA replication forks: "Breaking up is hard to do" NUCLEUS
Artículo2015 The COP9 signalosome is vital for timely repair of DNA double-strand breaks NUCLEIC ACIDS RESEARCH
Artículo2015 The Fanconi anemia pathway protects genome integrity from R-loops PLOS GENETICS
Ponencia2015 The role of the Mlp1 in genomic stability YEAST
Artículo2015 Type I phosphatidylinositol 4-phosphate 5-kinase homo- and heterodimerization determines its membrane localization and activity FASEB JOURNAL
Revisión2015 Vasoactive Intestinal Peptide (lVIP) Nanoparticles for Diagnostics and for Controlled and Targeted Drug Delivery PROTEIN AND PEPTIDE NANOPARTICLES FOR DRUG DELIVERY
Revisión2015 Yeast as a model system to study metabolic impact of selenium compounds MICROBIAL CELL
Ponencia2014 A 'Floating Boat Bridge' of cytochrome c molecules in plant respirasome FEBS JOURNAL
Letter2014 A common signalosome for programmed cell death in humans and plants CELL DEATH & DISEASE
Artículo2014 A genome-wide function of THSC/TREX-2 at active genes prevents transcription-replication collisions NUCLEIC ACIDS RESEARCH
Artículo2014 BRCA1 Accelerates CtIP-Mediated DNA-End Resection CELL REPORTS
Artículo2014 BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2 NATURE
Artículo2014 CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120(IIIB) binding to the cell surface PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Resumen congreso2014 Cdc7, Rad53 and Asf1 stabilize Rad52 binding to replicative DNA damage FEBS JOURNAL
Artículo2014 Chaperoned amyloid proteins for immune manipulation: alpha-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype IMMUNITY INFLAMMATION AND DISEASE
Artículo2014 Cleavage Factor I Links Transcription Termination to DNA Damage Response and Genome Integrity Maintenance in Saccharomyces cerevisiae PLOS GENETICS
Artículo2014 Cytochrome c(1) exhibits two binding sites for cytochrome c in plants BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Artículo2014 Cytoplasmic 5 '-3 ' exonuclease Xrnlp is also a genome-wide transcription factor in yeast FRONTIERS IN GENETICS
Artículo2014 Final Pre-40S Maturation Depends on the Functional Integrity of the 60S Subunit Ribosomal Protein L3 PLOS GENETICS
Ponencia2014 Introducción de componentes procedimentales al modelo metodológico en la asignatura de genética II del Grado de Biología I Seminario Iberoamericano de Innovación Docente de la Universidad Pablo de Olavide.
Ponencia2014 Introducción del aprendizaje por trabajo cooperativo en genética I I Seminario Iberoamericano de Innovación Docente de la Universidad Pablo de Olavide.
Editorial2014 Multiciliogenesis: Multicilin Directs Transcriptional Activation of Centriole Formation CURRENT BIOLOGY
Ponencia2014 New role of cytochrome c in programmed cell death FEBS JOURNAL
Artículo2014 Npl3, a new link between RNA-binding proteins and the maintenance of genome integrity CELL CYCLE
Revisión2014 Nuclear functions of prefoldin OPEN BIOLOGY
Artículo2014 Polyubiquitylation drives replisome disassembly at the termination of DNA replication SCIENCE
Artículo2014 Rad5 plays a major role in the cellular response to DNA damage during chromosome replication CELL REPORTS
Artículo2014 Rat1p maintains RNA polymerase II CTD phosphorylation balance RNA-A PUBLICATION OF THE RNA SOCIETY
Artículo2014 SAS-1 Is a C2 Domain Protein Critical for Centriole Integrity in C. elegans PLOS GENETICS
Artículo2014 Structural and Functional Analysis of Novel Human Cytochrome c Targets in Apoptosis MOLECULAR & CELLULAR PROTEOMICS
Póster2014 Sumoylation of CtIP controls DNA end resection Nuclear Regulation by Ubiquitin. 60 Benzon Symposium: (2014),
Artículo2014 The rem Mutations in the ATP-Binding Groove of the Rad3/XPD Helicase Lead to Xeroderma pigmentosum-Cockayne Syndrome-Like Phenotypes PLOS GENETICS
Artículo2014 The yeast and human FACT chromatinreorganizing complexes solve R-loop-mediated transcription-replication conflicts GENES & DEVELOPMENT
Revisión2014 Tolerating DNA damage during eukaryotic chromosome replication EXPERIMENTAL CELL RESEARCH
Artículo2014 Transcription and Recombination: When RNA Meets DNA COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
Artículo2014 Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability MOLECULAR CELL
Revisión2014 Using yeast to model calcium-related diseases: Example of the Hailey-Hailey disease BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Ponencia2013 Biointeractomics of cytochrome c under programmed cell death in plants and humans FEBS JOURNAL
Revisión2013 Causes of Genome Instability ANNUAL REVIEW OF GENETICS, VOL 47
Artículo2013 Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination NUCLEIC ACIDS RESEARCH
Revisión2013 Controlling DNA replication origins in response to DNA damage - inhibit globally, activate locally JOURNAL OF CELL SCIENCE
Artículo2013 Coordinated control of replication and transcription by a SAPK protects genomic integrity NATURE
Revisión2013 CXCL12-Mediated Murine Neural Progenitor Cell Movement Requires PI3K beta Activation MOLECULAR NEUROBIOLOGY
Artículo2013 Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells DEVELOPMENTAL CELL
Corrección2013 Discovering Regulators of Centriole Biogenesis through siRNA-Based Functional Genomics in Human Cells (vol 25, pg 555, 2013) DEVELOPMENTAL CELL
Artículo2013 Fluorescence Recovery After Photobleaching (FRAP) in the Fission Yeast Nucleus Bio-Protocol
Ponencia2013 From transcription to genome instability impact of RNAPII mutations YEAST
Artículo2013 Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis CELL
Artículo2013 Glyconanosomes: Disk-Shaped Nanomaterials for the Water Solubilization and Delivery of Hydrophobic Molecules ACS NANO
Artículo2013 Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid PLOS GENETICS
Artículo2013 HOMOGENEITY TESTS FOR MICHAELIS-MENTEN CURVES WITH APPLICATION TO FLUORESCENCE RESONANCE ENERGY TRANSFER DATA JOURNAL OF BIOLOGICAL SYSTEMS
Ponencia2013 How redox proteins form transient complexes in photosynthesis and respiration EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Artículo2013 Hsp70 Oligomerization Is Mediated by an Interaction between the Interdomain Linker and the Substrate-Binding Domain PLOS ONE
Resumen congreso2013 Invariant natural killer T cells could influence B cells changes in Dermatophagoides pteronyssinus immunotherapy ALLERGY
Resumen congreso2013 Invariant Natural Killer T Cells Populations in Peripheral Blood From Allergic Rhinitis Patients: Regulatory or Pathologic Role? JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Artículo2013 New Arabidopsis thaliana Cytochrome c Partners: A Look Into the Elusive Role of Cytochrome c in Programmed Cell Death in Plants MOLECULAR & CELLULAR PROTEOMICS
Artículo2013 New Tools to Study DNA Double-Strand Break Repair Pathway Choice PLOS ONE
Resumen congreso2013 Participation of invariant natural killer T cells in allergen-specific immunotherapy: regulatory or pathologic role? ALLERGY
Artículo2013 Pivoting of microtubules around the spindle pole accelerates kinetochore capture NATURE CELL BIOLOGY
Artículo2013 Preconditioning of Microglia by alpha-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation PLOS ONE
Artículo2013 Prognostic value of CtIP/RBBP8 expression in breast cancer CANCER MEDICINE
Artículo2013 R loops are linked to histone H3 S10 phosphorylation and chromatin condensation MOLECULAR CELL
Artículo2013 R-Loop Mediated Transcription-Associated Recombination in trf4 Delta Mutants Reveals New Links between RNA Surveillance and Genome Integrity PLOS ONE
Capítulo2013 R-Loops Brenner's Encyclopedia of Genetics: Second Edition
Artículo2013 Rad51 replication fork recruitment is required for DNA damage tolerance EMBO JOURNAL
Revisión2013 Recent Methodological Advances in the Analysis of Protein Tyrosine Nitration CHEMPHYSCHEM
Ponencia2013 Replication impairment as a source of transcription- and R-loop-associated recombination JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
Artículo2013 Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2013 Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage NUCLEIC ACIDS RESEARCH
Resumen congreso2013 The LRH-1 agonist BL001 improves human islet survival and blunts development of hyperglycaemia in the RIP-B7.1 mouse model of experimental autoimmune diabetes DIABETOLOGIA
Artículo2013 The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability GENES & DEVELOPMENT
Artículo2013 The prefoldin complex regulates chromatin dynamics during transcription elongation PLOS GENETICS
Revisión2013 Transcription coupled repair at the interface between transcription elongation and mRNP biogenesis BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Revisión2013 Transcription-Associated Genome Instability CHEMICAL REVIEWS
Artículo2013 Yeast Pol4 Promotes Tel1-Regulated Chromosomal Translocations PLOS GENETICS
Artículo2012 A matter of packaging: influence of nucleosome positioning on heterologous gene expression RECOMBINANT GENE EXPRESSION: REVIEWS AND PROTOCOLS, THIRD EDITION
Artículo2012 A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of alpha-Synuclein and beta-Synuclein BIOCHEMISTRY
Artículo2012 Adsorption of a Laccase from Fusarium Proliferatum on Au(111) and HOPG Electrodes: a Scanning Probe Microscopy and Electrochemical Approach INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
Capítulo2012 Alpha-synuclein and the immune response in Parkinson’s disease Towards New Therapies for Parkinson's Disease
Artículo2012 Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor EMBO JOURNAL
Artículo2012 Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4 NUCLEIC ACIDS RESEARCH
Artículo2012 Chemokine receptor oligomerization: A further step toward chemokine function IMMUNOLOGY LETTERS
Artículo2012 Complex Chromosomal Rearrangements Mediated by Break-Induced Replication Involve Structure-Selective Endonucleases PLOS GENETICS
Ponencia2012 Cytochrome c(1)-cytochrome c: an atypical transient complex FEBS JOURNAL
Ponencia2012 Cytochrome c(1): an old protein with novel functions FEBS JOURNAL
Artículo2012 Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange MOLECULAR AND CELLULAR BIOLOGY
Artículo2012 EBI2 regulates CXCL13-mediated responses by heterodimerization with CXCR5 FASEB JOURNAL
Resumen congreso2012 Engineered nanoparticles for improved vasoactive intestinal peptide (VIP) applications JOURNAL OF MOLECULAR NEUROSCIENCE
Artículo2012 Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth DEVELOPMENT
Resumen congreso2012 Funcionalización de nanopartículas con el neuropéptido VIP como estrategia de mejora de su potencial de aplicación en biomedicina Biosaia
Ponencia2012 Functional genomic screen in human cells reveals novel regulators of centriole number. MOLECULAR BIOLOGY OF THE CELL
Ponencia2012 Histone 3 K4, K14 and K56 post-translational modifications are not affected in hpr1 Delta FEBS JOURNAL
Artículo2012 HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4 JOURNAL OF EXPERIMENTAL MEDICINE
Artículo2012 Impaired manganese metabolism causes mitotic misregulation JOURNAL OF BIOLOGICAL CHEMISTRY
Resumen congreso2012 Improved drugability of vasoactive intestinal peptide (VIP) by nanotechnology for therapeutic selective targeting and immunomodulation JOURNAL OF NEUROIMMUNOLOGY
Resumen congreso2012 Invariant natural killer T-cells frequency in peripheral blood from allergic patients to house dust mite is higher than in tolerant controls ALLERGY
Resumen congreso2012 Involvement of wild-type alpha-synuclein and Parkinson's disease mutants in human monocyte-derived dendritic maturation MOLECULAR IMMUNOLOGY
Resumen congreso2012 Manganese homeostasis, genome stability and cell cycle FEBS JOURNAL
Artículo2012 Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Resumen congreso2012 Multicentre clinical trial phase I/II randomised, placebo-controlled study to evaluate safety and feasibility of therapy with two different doses of autologous mesenchymal stem cells in patients with SPMS who do not respond to treatment MULTIPLE SCLEROSIS
Artículo2012 Nanoporous silica microparticle interaction with toll-like receptor agonists in macrophages ACTA BIOMATERIALIA
Revisión2012 New clues to understand the role of THO and other functionally related factors in mRNP biogenesis BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Ponencia2012 New insights into the function of THO/TREX mRNP biogenesis and export factor in yeast and human cells FEBS JOURNAL
Revisión2012 One step back before moving forward: regulation of transcription elongation by arrest and backtracking FEBS LETTERS
Resumen congreso2012 Preconditioning of microglia with Parkinson-linked alpha-synuclein affects the response induced by Toll-like receptor (TLR) stimulation JOURNAL OF NEUROIMMUNOLOGY
Artículo2012 Propiedades terapéuticas del ajo MoleQla: revista de Ciencias de la Universidad Pablo de Olavide
Revisión2012 R Loops: From Transcription Byproducts to Threats to Genome Stability MOLECULAR CELL
Artículo2012 R-loops cause replication impairment and genome instability during meiosis EMBO REPORTS
Ponencia2012 R-loops in recombination-mediated genome instability FEBS JOURNAL
Artículo2012 The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development PLOS ONE
Capítulo2012 The Hsp70 chaperone system in Parkinson’s disease Etiology and Pathophysiology of Parkinson's Disease
Artículo2012 Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes NUCLEIC ACIDS RESEARCH
Ponencia2012 Topological stress and genome integrity maintenance FEBS JOURNAL
Ponencia2012 Uncovering the network that controls double strand break repair pathway choice FEBS JOURNAL
Artículo2011 A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors EMBO JOURNAL
Artículo2011 AID Induces Double-Strand Breaks at Immunoglobulin Switch Regions and c-MYC Causing Chromosomal Translocations in Yeast THO Mutants PLOS GENETICS
Artículo2011 Application of Flow Focusing to the Break-Up of a Magnetite Suspension Jet for the Production of Paramagnetic Microparticles JOURNAL OF NANOMATERIALS
Artículo2011 CD69 Modulates Sphingosine-1-Phosphate-Induced Migration of Skin Dendritic Cells JOURNAL OF INVESTIGATIVE DERMATOLOGY
Capítulo2011 Cellular responses to mitochondrial DNA damage in yeast Mitochondria: Structure, Functions and Dysfunctions
Artículo2011 Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency JOURNAL OF VIROLOGY
Artículo2011 Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2011 CtIP Mutations Cause Seckel and Jawad Syndromes PLOS GENETICS
Artículo2011 Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers BMC CANCER
Artículo2011 Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia NATURE GENETICS
Revisión2011 Dna strand break repair and human genetic disease ENCYCLOPEDIA OF LIFE SCIENCES (ELS)
Artículo2011 Engineered Nanoparticles for Improved Vasoactive Intestinal Peptide (VIP) Biomedical Applications Recent Patents on Nanomedicine
Artículo2011 FAK: Dynamic integration of guidance signals at the growth cone Cell Adhesion and Migration
Artículo2011 Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice NATURE
Artículo2011 Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway NATURE STRUCTURAL & MOLECULAR BIOLOGY
Capítulo2011 Genetic and Molecular Analysis of Mitotic Recombination in Saccharomyces cerevisiae DNA Recombination: Methods and Protocols
Artículo2011 Genome instability and transcription elongation impairment in human cells depleted of THO/TREX PLOS GENETICS
Artículo2011 Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles EMBO JOURNAL
Artículo2011 High-trhoughput screening of cytochrome C novel partners chlamydomonas ReindhartII Proteómica: revista de la Sociedad Española de Proteómica
Artículo2011 Histone H3K56 Acetylation, CAF1, and Rtt106 Coordinate Nucleosome Assembly and Stability of Advancing Replication Forks PLOS GENETICS
Artículo2011 Nab2 functions in the metabolism of RNA driven by polymerases II and III MOLECULAR BIOLOGY OF THE CELL
Artículo2011 New Suppressors of THO Mutations Identify Thp3 (Ypr045c)-Csn12 as a Protein Complex Involved in Transcription Elongation MOLECULAR AND CELLULAR BIOLOGY
Revisión2011 Proteomic tools for the analysis of transient interactions between metalloproteins FEBS JOURNAL
Revisión2011 Receptor oligomerization: A pivotal mechanism for regulating chemokine function PHARMACOLOGY & THERAPEUTICS
Artículo2011 Spindle positioning in human cells relies on proper centriole formation and on the microcephaly proteins CPAP and STIL JOURNAL OF CELL SCIENCE
Artículo2011 Technical Advance: Surface plasmon resonance-based analysis of CXCL12 binding using immobilized lentiviral particles Journal of leukocyte biology
Artículo2011 The Rad50 coiled-coil domain is indispensable for Mre11 complex functions NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo2011 The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear Pores CELL
Artículo2011 Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability MOLECULAR CELL
Artículo2011 Zim17/Tim15 links mitochondrial iron-sulfur cluster biosynthesis to nuclear genome stability NUCLEIC ACIDS RESEARCH
Artículo2010 A Postincision-Deficient TFIIH Causes Replication Fork Breakage and Uncovers Alternative Rad51-or Pol32-Mediated Restart Mechanisms MOLECULAR CELL
Artículo2010 Activity-Dependent Neuroprotective Protein (ADNP) Expression in the Amyloid Precursor Protein/Presenilin 1 Mouse Model of Alzheimer's Disease JOURNAL OF MOLECULAR NEUROSCIENCE
Artículo2010 C7 deficiency and meningococcal infection susceptibility in two Spanish families SCANDINAVIAN JOURNAL OF IMMUNOLOGY
Artículo2010 Chemokine receptor oligomerization: functional considerations Current Opinion in Pharmacology
Artículo2010 DNA resection in eukaryotes: deciding how to fix the break NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo2010 Electrochemical and AFM characterization on gold and carbon electrodes of a high redox potential laccase from Fusarium proliferatum BIOELECTROCHEMISTRY
Resumen congreso2010 Engineering of silver-protected VIP nanoparticles: chemical synthesis and functional characterization JOURNAL OF MOLECULAR NEUROSCIENCE
Artículo2010 Focal adhesion kinase functions downstream of Sema3A signaling during axonal remodeling MOLECULAR AND CELLULAR NEUROSCIENCE
Artículo2010 Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked Mutants PLOS ONE
Resumen congreso2010 Glial innate immunity generated by non-aggregated alpha-synuclein: Differences between wild-type and Parkinson's disease-linked mutants JOURNAL OF NEUROIMMUNOLOGY
Artículo2010 Ku70 corrupts DNA repair in the absence of the fanconi anemia pathway SCIENCE
Revisión2010 Nanotechnology-based manipulation of dendritic cells for enhanced immunotherapy strategies NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
Artículo2010 Replication fork breakage and re-start New insights into Rad3/XPD-associated deficiencies CELL CYCLE
Artículo2010 Silver nanoparticles interactions with the immune system: implications for health and disease SILVER NANOPARTICLES
Editorial2010 SILVER NANOPARTICLES Preface SILVER NANOPARTICLES
Artículo2010 Silver nanoparticles: sensing and imaging applications SILVER NANOPARTICLES
Ponencia2010 Structural and functional changes induced by tyrosine nitration in cytochrome c, a bi-functional protein BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Revisión2010 The interface between transcription and mRNP export: From THO to THSC/TREX-2 BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
Artículo2010 The Occurrence of the Biogenic Amine Melatonin in Olive Oil: Implications in Health and Disease Prevention Olives and olive oil in health and disease prevention (Second Edition)
Artículo2010 The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt FEBS JOURNAL
Revisión2010 The THO complex as a key mrnp biogénesis factor in development and cell differentiation Journal Of Biology (London. Print)
Artículo2010 The Yeast 5 '-3 ' Exonuclease Rat1p Functions during Transcription Elongation by RNA Polymerase II MOLECULAR CELL
Resumen congreso2010 Vasoactive intestinal peptide and its role in inflammatory diseases and self/non-self discrimination JOURNAL OF MOLECULAR NEUROSCIENCE
Artículo2009 A novel approach for organelle-specific DNA damage targeting reveals different susceptibility of mitochondrial DNA to the anticancer drugs camptothecin and topotecan NUCLEIC ACIDS RESEARCH
Artículo2009 Catalytic efficiency of natural and synthetic compounds used as laccase-mediators in oxidising veratryl alcohol and a kraft lignin, estimated by electrochemical analysis ELECTROCHIMICA ACTA
Artículo2009 Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip EMBO JOURNAL
Artículo2009 Chemical synthesis and characterization of silver-protected vasoactive intestinal peptide nanoparticles NANOMEDICINE
Capítulo2009 Chemokine receptor dimerization and chemotaxis Chemotaxis: methods and protocols
Artículo2009 Chromosomal Translocations Caused by Either Pol32-Dependent or Pol32-Independent Triparental Break-Induced Replication MOLECULAR AND CELLULAR BIOLOGY
Revisión2009 DNA Repair in Mammalian Cells CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2009 Dynamic Regulation of CXCR1 and CXCR2 Homo- and Heterodimers JOURNAL OF IMMUNOLOGY
Artículo2009 Fail-Safe Transcriptional Termination for Protein-Coding Genes in S. cerevisiae MOLECULAR CELL
Artículo2009 Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair PLOS GENETICS
Artículo2009 Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2009 Induction of Alloantigen-Specific Human T Regulatory Cells by Vasoactive Intestinal Peptide JOURNAL OF IMMUNOLOGY
Artículo2009 Methods to study transcription-coupled repair in chromatin. CHROMATIN PROTOCOLS, 3RD EDITION
Capítulo2009 Multiple approaches to the study of chemokine receptor homo‐ and heterodimerization METHODS IN ENZYMOLOGY, VOL 461: CHEMOKINES, PART B
Resumen congreso2009 New action mechanisms for ADNP/NAP as immunomodulatory players FEBS JOURNAL
Artículo2009 R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX NUCLEIC ACIDS RESEARCH
Artículo2009 Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes EMBO JOURNAL
Corrección2009 Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes (vol 28, pg 326, 2009) EMBO JOURNAL
Artículo2009 Regulon-Specific Control of Transcription Elongation across the Yeast Genome PLOS GENETICS
Artículo2009 Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery JOURNAL OF CELL BIOLOGY
Artículo2009 Stimulation of direct-repeat recombination by RNA polymerase III transcription DNA REPAIR
Artículo2009 The Dot1 Histone Methyltransferase and the Rad9 Checkpoint Adaptor Contribute to Cohesin-Dependent Double-Strand Break Repair by Sister Chromatid Recombination in Saccharomyces cerevisiae GENETICS
Artículo2009 The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants MOLECULAR AND CELLULAR BIOLOGY
Artículo2009 The Stress-activated Protein Kinase Hog1 Mediates S Phase Delay in Response to Osmostress MOLECULAR BIOLOGY OF THE CELL
Artículo2009 The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair NUCLEIC ACIDS RESEARCH
Artículo2009 Toll-like receptor stimulation differentially regulates vasoactive intestinal peptide type 2 receptor in macrophages JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Editorial2009 Transcription at the proximity of the nuclear pore A role for the THP1-SAC3-SUS1-CDC31 (THSC) complex RNA BIOLOGY
Artículo2009 Yeast Genetic Analysis Reveals the Involvement of Chromatin Reassembly Factors in Repressing HIV-1 Basal Transcription PLOS GENETICS
Artículo2008 A G(2)-Phase Microtubule-Damage Response in Fission Yeast GENETICS
Artículo2008 A Novel Class of mRNA-containing Cytoplasmic Granules Are Produced in Response to UV-Irradiation MOLECULAR BIOLOGY OF THE CELL
Artículo2008 A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants MOLECULAR GENETICS AND GENOMICS
Revisión2008 Alzheimer's disease beyond the genomic era: nuclear magnetic resonance (NMR) spectroscopy-based metabolomics JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Revisión2008 Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus CHROMOSOMA
Artículo2008 Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination GENES & DEVELOPMENT
Artículo2008 CDK targets Sae2 to control DNA-end resection and homologous recombination NATURE
Artículo2008 Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity MOLECULAR GENETICS AND GENOMICS
Revisión2008 Genome instability: a mechanistic view of its causes and consequences NATURE REVIEWS GENETICS
Editorial2008 Immune-based disorders: the challenges for translational immunology JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Revisión2008 Immunological features of alpha-synuclein in Parkinson's disease JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Artículo2008 Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation European Journal Of Immunology
Editorial2008 Nuclear Roadblocks for mRNA export CELL
Editorial2008 Terminating transcription in yeast: whether to be a 'nerd' or a 'rat' NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo2008 The THP1-SAC3-SUS1-CDC31 Complex Works in Transcription Elongation-mRNA Export Preventing RNA-mediated Genome Instability MOLECULAR BIOLOGY OF THE CELL
Artículo2008 Tiopronin monolayer-protected silver nanoparticles modulate IL-6 secretion mediated by Toll-like receptor ligands NANOMEDICINE
Artículo2007 A new connection of mRNP biogenesis and export with transcription-coupled repair NUCLEIC ACIDS RESEARCH
Artículo2007 Actions of PACAP and VIP on melanotrope cells of Xenopus laevis PEPTIDES
Artículo2007 Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2007 Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis MOLECULAR AND CELLULAR BIOLOGY
Artículo2007 Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication NUCLEIC ACIDS RESEARCH
Artículo2007 Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2007 Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain YEAST
Artículo2007 Focusing capillary jets close to the continuum limit NATURE PHYSICS
Artículo2007 Functional analysis of Saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis NUCLEIC ACIDS RESEARCH
Editorial2007 How to exchange your partner. Workshop on recombination mechanisms and the maintenance of genomic stability EMBO REPORTS
Artículo2007 Impairment of transcription elongation by R-loops in vitro BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Revisión2007 Meiotic recombination in Caenorhabditis elegans CHROMOSOME RESEARCH
Artículo2007 Melatonin is a phytochemical in olive oil FOOD CHEMISTRY
Artículo2007 Microscopic and transcriptome analyses of early colonization of tomato roots by Trichoderma harzianum INTERNATIONAL MICROBIOLOGY
Libro2007 Molecular genetics of recombination Molecular genetics of recombination
Artículo2007 Multiprotein expression strategy for structural biology of eukaryotic complexes STRUCTURE
Corrección2007 Multiprotein expression strategy for structural biology of eukaryotic complexes (vol 15, pg 275, 2007) STRUCTURE
Resumen congreso2007 New cellular and humural immune-targeted mechanisms by VIP/ADNP neuropeptides with prospective therapeutic uses FEBS JOURNAL
Artículo2007 Nucleoporins prevent DNA damage accumulation by modulating Ulp1-dependent sumoylation processes MOLECULAR BIOLOGY OF THE CELL
Artículo2007 QID74 Cell wall protein of Trichoderma harzianum is involved in cell protection and adherence to hydrophobic surfaces FUNGAL GENETICS AND BIOLOGY
Artículo2007 Sister chromatid recombination Topics in Current Genetics
Artículo2007 SMC proteins, new players in the maintenance of genomic stability CELL CYCLE
Artículo2007 Structures of T cell immunoglobulin mucin protein 4 show a metal-ion-dependent ligand binding site where phosphatidylserine binds IMMUNITY
Artículo2007 Structures of T cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family IMMUNITY
Artículo2007 Tuning immune tolerance with vasoactive intestinal peptide: A new therapeutic approach for immune disorders PEPTIDES
Artículo2006 A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites EMBO JOURNAL
Artículo2006 A gene-specific requirement for FACT during transcription is related to the chromatin organization of the transcribed region MOLECULAR AND CELLULAR BIOLOGY
Artículo2006 Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates EMBO REPORTS
Artículo2006 An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination MOLECULAR AND CELLULAR BIOLOGY
Artículo2006 CD161 (human NKR-P1A) signaling in NK cells involves the activation of acid sphingomyelinase JOURNAL OF IMMUNOLOGY
Editorial2006 DNA repair: From molecular mechanism to human disease DNA REPAIR
Artículo2006 Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange EMBO REPORTS
Artículo2006 Early attack and subsequent changes produced in an industrial lignin by a fungal laccase and a laccase-mediator system: an analytical approach APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Revisión2006 Enzyme promiscuity: evolutionary and mechanistic aspects Current Opinion in Chemical Biology
Capítulo2006 High-throughput Screens and Selections of Enzyme-encoding Genes Enzyme Assays: High-throughput Screening, Genetic Selection and Fingerprinting
Artículo2006 Histomorphogenesis and immunohistochemical study of the bovine pineal gland (Bos taurus) during prenatal development (160 days of gestation to birth) HISTOLOGY AND HISTOPATHOLOGY
Artículo2006 Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation DNA REPAIR
Letter2006 Impairment of the melatonin rhythm in children with Sanfilippo syndrome JOURNAL OF PINEAL RESEARCH
Artículo2006 Molecular defects of the C7 gene in two patients with complement C7 deficiency IMMUNOLOGY
Artículo2006 NAP, a peptide derived from the activity-dependent neuroprotective protein, modulates macrophage function ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Artículo2006 Production, partial characterization and mass spectrometric studies of the extracellular laccase activity from Fusarium proliferatum APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Artículo2006 Protective role for plasmid DNA-mediated VIP gene transfer in non-obese diabetic mice ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Artículo2006 Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex MOLECULAR AND CELLULAR BIOLOGY
Artículo2006 RUNX3 negatively regulates CD36 expression in myeloid cell lines JOURNAL OF IMMUNOLOGY
Artículo2006 Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination NATURE CELL BIOLOGY
Artículo2006 SOCS up-regulation mobilizes autologous stem cells through CXCR4 blockade BLOOD
Artículo2006 Straightforward production of encoded microbeads by Flow Focusing: Potential applications for biomolecule detection INTERNATIONAL JOURNAL OF PHARMACEUTICS
Artículo2006 The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase BIOCHEMISTRY
Revisión2006 The modulatory role of melatonin on immune responsiveness CURRENT OPINION IN INVESTIGATIONAL DRUGS
Resumen congreso2006 The NAP peptide derived from the activity-dependent neuroprotective protein (ADNP) is a new immunomodulator with therapeutic effects in the adoptive transfer model of experimental allergic encephalomyelitis JOURNAL OF IMMUNOLOGY
Artículo2006 Therapeutic effect of vasoactive intestinal peptide on experimental autoimmune encephalomyelitis - Down-regulation of inflammatory and autoimmune responses AMERICAN JOURNAL OF PATHOLOGY
Artículo2006 Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants MOLECULAR AND CELLULAR BIOLOGY
Artículo2006 Timing of adequate antibiotic therapy is a greater determinant of outcome than are TNF and IL-10 polymorphisms in patients with sepsis CRITICAL CARE
Artículo2006 Two-dimensional agarose gel analysis of DNA replication intermediates. HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Artículo2006 VIP prevents experimental multiple sclerosis by downregulating both inflammatory and autoimmune components of the disease ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Revisión2005 Cotranscriptional mRNP assembly: from the DNA to the nuclear pore CURRENT OPINION IN CELL BIOLOGY
Artículo2005 Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state PROTEIN ENGINEERING DESIGN & SELECTION
Revisión2005 Directed evolution of proteins for heterologous expression and stability Current Opinion in Structural Biology
Artículo2005 Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans EMBO JOURNAL
Artículo2005 Impairment of replication fork progression mediates RNA polII transcription-associated recombination EMBO JOURNAL
Artículo2005 Interdependence between transcription and mRNP processing and export, and its impact on genetic stability MOLECULAR CELL
Editorial2005 mRNA processing and genomic instability NATURE STRUCTURAL & MOLECULAR BIOLOGY
Resumen congreso2005 NAP, a peptide derived from activity-dependent neuroprotective protein (ADNP), is a potent modulator innate and adaptive immunity: Prevention of autoimmune experimental encephalomyelitis REGULATORY PEPTIDES
Artículo2005 Partial depletion of histone h4 increases homologous recombination-mediated genetic instability MOLECULAR AND CELLULAR BIOLOGY
Artículo2005 Regulated recruitment of DC-SIGN to cell-cell contact regions during zymosan-induced human dendritic cell aggregation Journal of leukocyte biology
Artículo2005 Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily BIOCHEMISTRY
Artículo2005 The 'evolvability' of promiscuous protein functions NATURE GENETICS
Artículo2005 The use of melatonin as a vaccine agent VACCINE
Artículo2005 Use of full-length recombinant calflagin and its C fragment for improvement of diagnosis of Trypanosoma cruzi infection JOURNAL OF CLINICAL MICROBIOLOGY
Artículo2005 Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Resumen congreso2005 VIP gene delivery protects non-obese diabetic (NOD/LtJ) mice from cyclophosphamide-accelerated diabetes REGULATORY PEPTIDES
Artículo2004 A member of the fizzy-related family of APC activators is regulated by cAMP and is required at different stages of plant infection by Ustilago maydis JOURNAL OF CELL SCIENCE
Artículo2004 A novel yeast mutation, rad52-L89F, causes a specific defect in Rad51-independent recombination that correlates with a reduced ability of RAD52-L89F to interact with RAD59 GENETICS
Letter2004 A unified nomenclature for protein subunits of Mediator complexes linking transcriptional regulators to RNA polymerase II MOLECULAR CELL
Artículo2004 Characterization of B-type cyclins in the smut fungus Ustilago maydis: roles in morphogenesis and pathogenicity JOURNAL OF CELL SCIENCE
Artículo2004 Complement component C7 deficiency in two Spanish families IMMUNOLOGY
Artículo2004 Effects of celecoxib on acid-challenged gastric mucosa of rats: Comparison with metamizol and piroxicam DIGESTIVE DISEASES AND SCIENCES
Artículo2004 Increased antifungal and chitinase specific activities of Trichoderma harzianum CECT 2413 by addition of a cellulose binding domain APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Artículo2004 Molecular evidence indicating that the yeast PAF complex is required for transcription elongation EMBO REPORTS
Artículo2004 mRNA expression of nuclear receptor RZR/ROR alpha, melatonin membrane receptor MT1, and hydroxindole-O-methyltransferase in different populations of human immune cells JOURNAL OF PINEAL RESEARCH
Artículo2004 Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae RNA-A PUBLICATION OF THE RNA SOCIETY
Artículo2004 Reaction cycle of the yeast Isw2 chromatin remodeling complex EMBO JOURNAL
Artículo2004 Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2004 RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line CANCER LETTERS
Artículo2004 The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange EMBO REPORTS
Artículo2004 The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor European Journal Of Immunology
Artículo2004 The many faces of VIP in neuroimmunology: a cytokine rather a neuropeptide? FASEB JOURNAL
Revisión2004 The significance of vasoactive intestinal peptide in immunomodulation PHARMACOLOGICAL REVIEWS
Ponencia2003 Analysis of replication fork movement in mutants defective in RNA polymerase II transcription elongation. YEAST
Artículo2003 Chromatin remodeling activities act on UV-damaged nucleosomes and modulate DNA damage accessibility to photolyase JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2003 Complement component C7 deficiency in a Spanish family CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Editorial2003 Control of cross-over by single-strand DNA resection TRENDS IN GENETICS
Artículo2003 Cotranscriptionally formed DNA : RNA hybrids mediate transcription elongation impairment and transcription-associated recombination MOLECULAR CELL
Artículo2003 Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast MOLECULAR CELL
Ponencia2003 Equal sister-chromatid exchange is a major mechanism of double-strand-break repair in yeast YEAST
Ponencia2003 Impairment of chromatin assembly confers hyperrecombination. YEAST
Artículo2003 Melatonin inhibits telomerase activity in the MCF-7 tumor cell line both in vivo and in vitro JOURNAL OF PINEAL RESEARCH
Revisión2003 Mitotic recombination in Saccharomyces cerevisiae CURRENT GENETICS
Artículo2003 Molecular evidence for a positive role of Spt4 in transcription elongation EMBO JOURNAL
Artículo2003 Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2003 Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2003 New Saccharomyces cerevisiae baker's yeast displaying enhanced resistance to freezing JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2003 Pheromone-induced G(2) arrest in the phytopathogenic fungus Ustilago maydis EUKARYOTIC CELL
Artículo2003 Purification of the 67-kDa lectin-like glycoprotein of Trypanosoma cruzi, LLGP-67, and its evaluation as a relevant antigen for the diagnosis of human infection FEMS MICROBIOLOGY LETTERS
Artículo2003 Rad52-independent accumulation of joint circular minichromosomes during s phase in saccharomyces cerevisiae MOLECULAR AND CELLULAR BIOLOGY
Artículo2003 Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae: New insights into transcription-associated recombination GENETICS
Artículo2003 Relationship between G+C content, ORF-length and mRNA concentration in Saccharomyces cerevisiae YEAST
Revisión2003 VIP- and PACAP-mediated immunomodulation as prospective therapeutic tools TRENDS IN MOLECULAR MEDICINE
Artículo2002 Characterization of two highly similar Rad51 homologs of Physcomitrella patens JOURNAL OF MOLECULAR BIOLOGY
Artículo2002 Defective nucleotide excision repair in yeast hpr1 and tho2 mutants NUCLEIC ACIDS RESEARCH
Artículo2002 Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis NATURE GENETICS
Artículo2002 La recombinación homóloga del ADN Investigación y Ciencia
Artículo2002 Mechanisms involved in protection afforded by L-arginine in Ibuprofen-induced gastric damage - Role of nitric oxide and prostaglandins DIGESTIVE DISEASES AND SCIENCES
Artículo2002 Melatonin prevents focal rat cerebellum injury as assessed by induction of heat shock protein (HO-1) following subarachnoid injections of lysed blood Neuroscience Letters
Artículo2002 Oxidative stress induced by phenylketonuria in the rat: Prevention by melatonin, vitamin E, and vitamin C JOURNAL OF NEUROSCIENCE RESEARCH
Revisión2002 The connection between transcription and genomic instability EMBO JOURNAL
Artículo2002 The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability EMBO JOURNAL
Artículo2002 Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae GENETICS
Artículo2002 TREX is a conserved complex coupling transcription with messenger RNA export NATURE
Artículo2002 Trypanosoma cruzi: identification of a galactose-binding protein that binds to cell surface of human erythrocytes and is involved in cell invasion by the parasite EXPERIMENTAL PARASITOLOGY
Artículo2002 Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit LPS-stimulated MIP-1 alpha production and mRNA expression CYTOKINE
Artículo2001 A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination GENETICS
Editorial2001 Double-strand break repair: are Rad51/RecA-DNA joints barriers to DNA replication? TRENDS IN GENETICS
Ponencia2001 Genetic and molecular characterization of THO1, a multicopy supressor of, hpr1. YEAST
Ponencia2001 Genetics and molecular analysis of thp1, a yeast gene controlling transcription and recombination. YEAST
Artículo2001 Hpr1 is preferentially required for transcription of either long or G+C-Rich DNA sequences in Saccharomyces cerevisiae MOLECULAR AND CELLULAR BIOLOGY
Ponencia2001 Isolation and genetic analysis of novel HPR1 and THO2 mutations that differentially affect transcription and recombination. YEAST
Capítulo2001 Mechanisms and genetic control of dna repeat recombination in s. cerevisiae Recent Research Developments in Human Genetics
Artículo2001 Nucleosome positioning at the replication fork EMBO JOURNAL
Artículo2001 Pleiotropic functions of a Streptomyces pristinaespiralis autoregulator receptor in development, antibiotic biosynthesis, and expression of a superoxide dismutase JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2001 Yeast spt6-140 mutation, affecting chromatin and transcription, preferentially increases recombination in which Rad51p-mediated strand exchange is dispensable GENETICS
Artículo2000 A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae EMBO JOURNAL
Artículo2000 Architecture of the replication fork stalled at the 3 end of yeast ribosomal genes MOLECULAR AND CELLULAR BIOLOGY
Artículo2000 Cell cycle regulated expression and phosphorylation of hpttg proto-oncogene product ONCOGENE
Artículo2000 Correlation between nuclear melatonin receptor expression and enhanced cytokine production in human lymphocytic and monocytic cell lines JOURNAL OF PINEAL RESEARCH
Artículo2000 DNA repair in a yeast origin of replication: contributions of photolyase and nucleotide excision repair NUCLEIC ACIDS RESEARCH
Corrección2000 Erratum: Immunobiology of vasoactive intestinal peptid (VIP) (Immunology Today (2000) vol. 21(1), (7-11)) Immunology Today
Artículo2000 Functional and molecular characterization of VIP receptor-effector system in rat developing immunocompetent cells: G protein involvement JOURNAL OF NEUROIMMUNOLOGY
Artículo2000 Identification of G-protein coupled receptor subunits in normal human dental pulp JOURNAL OF ENDODONTICS
Artículo2000 Immunobiology of vasoactive intestinal peptide (VIP) Immunology Today
Corrección2000 Immunobiology of vasoactive intestinal peptide (VIP) (vol 21, pg 7, 2000) Immunology Today
Artículo2000 Involvement of nuclear receptors in the enhanced IL-2 production by melatonin in Jurkat cells ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Revisión2000 Mitotic recombination in yeast: elements controlling its incidence YEAST
Ponencia2000 Nitric oxide mechanisms in protection afforded by L-arginine in ibuprofen induced gastric toxicity. GASTROENTEROLOGY
Artículo2000 Nuclear receptors are involved in the enhanced IL-6 production by melatonin in U937 cells Biological Signals and Receptors
Artículo2000 Postnatal development of vasoactive intestinal peptide receptor-effector system in rat immunocompetent cells ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Artículo2000 RAD52-dependent and -independent homologous recombination initiated by Flp recombinase at a single FRT site flanked by direct repeats MOLECULAR & GENERAL GENETICS
Artículo1999 cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein MOLECULAR BRAIN RESEARCH
Artículo1999 Characterization of membrane melatonin receptor in mouse peritoneal macrophages: Inhibition of adenylyl cyclase by a pertussis toxin-sensitive G protein JOURNAL OF NEUROIMMUNOLOGY
Artículo1999 Construction and genetic analysis of S-cerevisiae deletants of six novel ORFs from chromosome II YEAST
Artículo1999 Electron microscopic analysis reveals that replication factor c is sequestered by single-stranded dna. NUCLEIC ACIDS RESEARCH
Revisión1999 In vivo mapping of nucleosomes using psoralen-DNA crosslinking and primer extension. HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Artículo1999 Melatonin activates Th1 lymphocytes by increasing IL-12 production LIFE SCIENCES
Artículo1999 Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide-induced multiple organ dysfunction syndrome in rats FASEB JOURNAL
Artículo1999 Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase- activation polypeptide (PACAP) protect mice from lethal endotoxemia through the inhibition of TNF-α and IL-6 JOURNAL OF IMMUNOLOGY
Artículo1999 Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit endotoxin-induced TNF-α production by macrophages: In vitro and in vivo studies JOURNAL OF IMMUNOLOGY
Artículo1998 A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination EMBO JOURNAL
Ponencia1998 Effect of chlorhexidine digluconate on substrate adherence capacity of macrophages. JOURNAL OF DENTAL RESEARCH
Artículo1998 Genetic stability and DNA rearrangements associated with a 2 x 1.1-kb perfect palindrome in Escherichia coli MOLECULAR & GENERAL GENETICS
Artículo1998 Histone acetylation facilitates rna polii transcription of the drosophila hsp26 gene in chromatin EMBO JOURNAL
Artículo1998 In vivo mapping of nucleosomes using psoralen-dna crosslinking and primer extension NUCLEIC ACIDS RESEARCH
Resumen congreso1998 Protein expression of heterotrimeric G-protein subunits in normal human dental pulp. JOURNAL OF DENTAL RESEARCH
Ponencia1998 The bleaching agent Amosan (R) (sodium perborate) inhibits macrophage adhesion. JOURNAL OF DENTAL RESEARCH
Ponencia1998 The bleaching agent amosanr (sodium perborate) inhibits macrophage adhesion JOURNAL OF DENTAL RESEARCH
Artículo1998 Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide modulate endotoxin-induced IL-6 production by murine peritoneal macrophages Journal of leukocyte biology
Artículo1998 VIP and PACAP enhance IL-6 release and mRNA levels in resting peritoneal macrophages: in vitro and in vivo studies JOURNAL OF NEUROIMMUNOLOGY
Artículo1997 Adenosine deaminase is a specific partner for the Grb2 isoform Grb3-3 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Ponencia1997 Characterization of gene expression of the membrane melatonin receptor in rat thymus and spleen PINEAL UPDATE
Artículo1997 Characterization of VIP receptor-effector system antagonists in rat and mouse peritoneal macrophages EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo1997 Differential adrenergic regulation of rat pineal cyclic AMP production and N-acetyltransferase activity during postnatal development: involvement of G(alpha S) and G(alpha i1-2) proteins JOURNAL OF ENDOCRINOLOGY
Artículo1997 Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase ONCOGENE
Revisión1997 Expression of membrane melatonin receptor mRNA in rat thymus and spleen THERAPEUTIC POTENTIAL OF MELATONIN
Artículo1997 Expression of the Mel1a-melatonin receptor mRNA in T and B subsets of lymphocytes from rat thymus and spleen FASEB JOURNAL
Artículo1997 Functional characterization and mRNA expression of pituitary adenylate cyclase activating polypeptide (PACAP) type I receptors in rat peritoneal macrophages BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo1997 Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin JOURNAL OF CELLULAR BIOCHEMISTRY
Capítulo1997 Mechanisms of action of melatonin on the human immune system: membrane versus nuclear receptors THERAPEUTIC POTENTIAL OF MELATONIN
Artículo1997 Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene. EMBO JOURNAL
Artículo1997 Recombination between DNA repeats in yeast hpr1 Delta cells is linked to transcription elongation EMBO JOURNAL
Artículo1997 Signal Transduction for Melatonin in Human Lymphocytes: Involvement of a Pertussis Toxin-Sensitive G Protein JOURNAL OF IMMUNOLOGY
Artículo1997 The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability GENES & DEVELOPMENT
Artículo1997 The yeast HRS1 gene is involved in positive and negative regulation of transcription and shows genetic characteristics similar to SIN4 and GAL11 GENETICS
Artículo1996 Characterization of adenylyl cyclase stimulated by VIP in rat and mouse peritoneal macrophage membranes BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo1996 Characterization of binding sites for beta-adrenergic agonists and vasoactive intestinal peptide in the rat harderian gland MICROSCOPY RESEARCH AND TECHNIQUE
Artículo1996 Characterization of gene expression of VIP and VIP1-receptor in rat peritoneal lymphocytes and macrophages REGULATORY PEPTIDES
Artículo1996 Differential intrachromosomal hyper-recombination phenotype of spt4 and spt6 mutants of S-cerevisiae CURRENT GENETICS
Artículo1996 Expression of vasoactive intestinal peptide binding sites in rat peritoneal macrophages is stimulated by inflammatory stimulus JOURNAL OF NEUROIMMUNOLOGY
Revisión1996 Functional and molecular characterization of VIP receptors and signal transduction in human and rodent immune systems ADVANCES IN NEUROIMMUNOLOGY
Artículo1996 La recombinación genética y su relación con la transcripción Industria Farmacéutica
Artículo1996 Melatonin reduces nitric oxide synthase activity in rat hypothalamus JOURNAL OF PINEAL RESEARCH
Revisión1996 Mutations in the yeast SRB2 general transcription factor suppress hpr1- induced recombination and show defects in DNA repair GENETICS
Artículo1996 Structure of the dehydrin tas14 gene of tomato and its developmental and environmental regulation in transgenic tobacco PLANT MOLECULAR BIOLOGY
Artículo1996 Tag dna polymerase blockage at pyrimidine dimers. NUCLEIC ACIDS RESEARCH
Artículo1996 The yeast HRS1 gene encodes a polyglutamine-rich nuclear protein required for spontaneous and hpr1-induced deletions between direct repeats GENETICS
Artículo1996 Thymosin alpha 1 interacts with the VIP receptor-effector system in rat and mouse immunocompetent cells IMMUNOPHARMACOLOGY
Ponencia1995 Chromatin properties affecting UV-induced damage formation and repair RADIATION RESEARCH 1895-1995, CONGRESS PROCEEDINGS
Artículo1995 Genetic-evidence for different rad52-dependent intrachromosomal recombination pathways in saccharomyces-cerevisiae CURRENT GENETICS
Artículo1995 HOMOLOGOUS REGULATION OF VASOACTIVE-INTESTINAL-PEPTIDE (VIP) RECEPTORS ON RAT PERITONEAL-MACROPHAGES PEPTIDES
Artículo1995 Immunomodulatory role of melatonin - specific binding-sites in human and rodent lymphoid-cells JOURNAL OF PINEAL RESEARCH
Artículo1995 Isolation and genetic analysis of extragenic suppressors of the hyper- deletion phenotype of the Saccharomyces cerevisiae hpr1Δ mutation GENETICS
Corrección1995 Isolation and genetic analysis of extragenic suppressors of the hyper-deletion phenotype of the Saccharomyces cerevisiae hpr1Δ mutation (Genetics (January, 1995) 139 (57-66)) GENETICS
Capítulo1995 Recombinación y estabilidad de secuencias repetidas de ADN en levaduras Microbiología y genética molecular
Artículo1995 Role of reciprocal exchange, one-ended invasion crossover and single- strand annealing on inverted and direct repeat recombination in yeast: Different requirements for the RAD1, RAD10, and RAD52 genes GENETICS
Artículo1995 SPECIFIC BINDING OF 2-[I-125]IODOMELATONIN BY RAT SPLENOCYTES - CHARACTERIZATION AND ITS ROLE ON REGULATION OF CYCLIC-AMP PRODUCTION JOURNAL OF NEUROIMMUNOLOGY
Artículo1995 VIP RECEPTOR-EFFECTOR SYSTEM IN RAT HARDERIAN-GLAND AND ITS COUPLING TO ACTIVATION OF TYPE-II THYROXINE 5'-DEIODINASE PEPTIDES
Artículo1994 Expression, tissue distribution and subcellular-localization of dehydrin tas14 in salt-stressed tomato plants PLANT MOLECULAR BIOLOGY
Artículo1994 Formamide sensitivity: A novel conditional phenotype in yeast GENETICS
Artículo1994 Increase in incidence of chromosome instability and nonconservative recombination between repeats in saccharomyces-cerevisiae hpr1-delta strains MOLECULAR & GENERAL GENETICS
Nota1994 New in-vivo cloning methods by homologous recombination in yeast CURRENT GENETICS
Artículo1994 Peptide-t from human-immunodeficiency-virus does not interact with vip receptor-effector system in immunocompetent cells of rat and mouse BIOSCIENCE REPORTS
Letter1994 Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum LIFE SCIENCES
Ponencia1991 Análisis molecular del estrés salino I Reunión de biología molecular de plantas : Salamanca 19-20 septiembre 1991
Artículo1991 The hyper-gene conversion hpr5-1 mutation of Saccharomyces cerevisiae is an allele of the SRS2/RADH gene GENETICS
Artículo1990 High-levels of chromosome instability in polyploids of saccharomyces-cerevisiae Mutation Research
Artículo1990 Hpr1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the saccharomyces-cerevisiae top1 gene MOLECULAR AND CELLULAR BIOLOGY
Artículo1990 Molecular analysis of RGP1, a new yeast gene required for proper mitotic growth NUCLEIC ACIDS RESEARCH
Artículo1990 Nucleotide-sequence and characterization of temperature-sensitive pol1 mutants of saccharomyces-cerevisiae GENE
Resumen congreso1989 ANALYSIS OF HYPER-RECOMBINATION MUTANTS OF YEAST GENETICS
Artículo1989 Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1 GENETICS
Artículo1989 Synergistic effects of ethanol and temperature on yeast mitochondria CURRENT MICROBIOLOGY
Artículo1989 The phosphofructokinase genes of yeast evolved from two duplication events GENE
Artículo1989 Yeast intrachromosomal recombination: long gene conversion tracts are preferentially associated with reciprocal exchange and require the RAD1 and RAD3 gene products GENETICS
Artículo1988 Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations. GENETICS
Artículo1988 Mitotic gene conversion of large DNA heterologies in saccharomyces-cerevisiae MOLECULAR & GENERAL GENETICS
Nota1988 Relationship between growth, fermentation, and respiration rates in saccharomyces cerevisiae - a study based on the analysis of the yield ypx BIOTECHNOLOGY AND BIOENGINEERING
Artículo1987 Mutations suppressing the effects of a deletion of the phosphoglucose isomerase gene pgi1 in saccharomyces-cerevisiae CURRENT GENETICS
Artículo1986 Deletion of the phosphoglucose isomerase structural gene makes growth and sporulation glucose dependent in saccharomyces-cerevisiae MOLECULAR & GENERAL GENETICS
Artículo1986 Ethanol-sensitive mutants of Saccharomyces-cerevisiae ARCHIVES OF MICROBIOLOGY
Artículo1986 Isolation and molecular analysis of the phosphoglucose isomerase structural gene of saccharomyces-cerevisiae MOLECULAR & GENERAL GENETICS
Artículo1985 Role of mitochondria in ethanol tolerance of saccharomyces-cerevisiae ARCHIVES OF MICROBIOLOGY
Artículo1985 Specific gene probes as tools in yeast taxonomy CURRENT GENETICS
Artículo1984 Instability of saccharomyces-cerevisiae heterokaryons CURRENT GENETICS
Artículo1983 Alcohol-and sucrose- tolerant wine yeast strains. CIENCIA BIOLÓGICA
Artículo1983 Selection of wine yeasts for growth and fermentation in the presence of ethanol and sucrose APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Proyectos de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/06/2024 31/05/2026 Explorando las asociaciones moleculares de ADAR y KRAS y sus implicaciones terapéuticas en cáncer de pulmón y páncreas. (SNRGS247052PRAD) Fundación AECC (Nacional) 20.000,00 €
01/09/2023 31/08/2026 Nuevos mecanismos reguladores de la expresión génica asociados a la actividad de la topoisomerasa II (RETOP) (PID2022-139253NB-I00) Ministerio de Ciencia e Innovación (Nacional) 225.000,00 €
01/09/2023 31/08/2026 Quinasas de señalización y mecanismos de inmunoregulación en esclerosis lateral amiotrófica (ELA) (PID2022-140838OB-I00) Ministerio de Ciencia e Innovación (Nacional) 200.000,00 €
01/09/2023 31/08/2026 CCAR2: En la encrucijada entre la reparación del ADN, el metabolismo celular y la señalización por estrés (PID2022-136791NB-I00) Ministerio de Ciencia e Innovación (Nacional) 477.500,00 €
01/09/2023 31/08/2026 Papel del manganeso en el daño celular y la enfermedad (PID2022-140466NB-I00) Ministerio de Ciencia e Innovación (Nacional) 190.000,00 €
01/09/2023 31/08/2026 Función de la cromatina en la inestabilidad genómica asociada a transcripción (PID2022-138251NB-I00) Ministerio de Ciencia e Innovación (Nacional) 512.500,00 €
01/09/2023 31/08/2026 Estudio de nuevas dianas para el tratamiento del síndrome de Aicardi-Goutières (PID2022-140603NB-I00) Ministerio de Ciencia e Innovación (Nacional) 162.500,00 €
01/09/2023 31/08/2025 Identificación de determinantes genéticos de la Sumoylación de Histonas (CNS2022-135216) Ministerio de Ciencia e Innovación (Nacional) 199.625,90 €
01/09/2023 31/08/2025 La interacción entre la topología del ADN y el paisaje epigenético (CNS2022-135600) Ministerio de Ciencia e Innovación (Nacional) 193.225,00 €
01/09/2023 31/08/2025 Estudio de la tumorogénesis asociada a la deficiencia de la ruta de reparación del DNA Anemia de Fanconi (CNS2022-136055) Ministerio de Ciencia e Innovación (Nacional) 199.650,00 €
01/07/2023 31/12/2023 Compensación de gastos de desplazamiento al proceso de selección de la convocatoria Caixaimpulse Innovación 2023 (CAIXAIMPULSE TRAVEL) Fundación La Caixa (Autonómico) 300,00 €
16/05/2023 15/05/2025 Molecular and genomic analysis of the role of the ARP2/3 complex on Transcription-Replication collisions (IHMC22/00044) Ministerio de Ciencia e Innovación (Instituto de Salud Carlos III) (Nacional) 158.428,30 €
15/12/2022 15/12/2025 R-loop-mediated genome instability factors in cancer (HR22-00073) Fundación La Caixa (Autonómico) 500.000,00 €
02/12/2022 31/12/2025 Regulación de la transcripción y del metabolismo del RNA en respuesta a tratamiento de quimioterapia (PROYEXCEL_00835) Junta de Andalucía (Consejería de Transformación Económica, Industria, Conocimiento y Universidades) (Autonómico) 160.080,00 €
01/12/2022 30/11/2026 Papel de la edición de ARN mediada por ADAR en diferentes células tumorales carentes de BRCA (AECC_POSTD222709PRD) Fundación AECC (Nacional) 160.000,00 €
01/09/2022 31/08/2025 Papel de ATR/ATM en la respuesta al daño en el ADN durante meiosis (PID2021-123850NB-I00) Ministerio de Ciencia e Innovación (Nacional) 121.000,00 €
01/09/2022 31/08/2025 Consecuencias de la modificación del genoma con ubiquitina similares (PID2021-122361NA-I00) Ministerio de Ciencia e Innovación (Nacional) 163.350,00 €
01/09/2022 31/08/2025 La Anemia de Fanconi: Mecanismos moleculares de la inestabilidad cromosomica asociada a defectos de la replicación del DNA (PID2021-128988OB-I00) Ministerio de Ciencia e Innovación (Nacional) 223.850,00 €
01/09/2022 31/12/2024 H3K37m1: Distribución genómica y papel en la iniciación de la replicación del ADN (PID2021-127432NA-I00) Ministerio de Ciencia e Innovación (Nacional) 159.720,00 €
01/01/2022 30/06/2025 Análisis Estructural y Funcional de la Red de Interacciones del Citocromo c en la Comunicación Mitocondria-Núcleo (PID2021-126663NB-I00) Ministerio de Ciencia e Innovación (Nacional) 242.000,00 €
01/01/2022 31/05/2023 La ruta Anemia de Fanconi y su papel en la estabilidad de la cromatina naciente durante los conflictos transcripción-replicación (US-1381081) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 79.328,00 €
01/01/2022 31/05/2023 Replication fork stability and arrest in eukaryotic cells (US-1380058) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 30.000,00 €
05/10/2021 30/06/2023 Un enfoque fosfoproteómico hacia la comprensión y el tratamiento de una enfermedad rara (P20_01220) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 75.000,00 €
05/10/2021 31/03/2023 Mecanismos moleculares de una proteína de la familia BET en la respuesta neuroinflamatoria asociada a proteinopatías neurodegenerativas (P20_01097) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 75.000,00 €
05/10/2021 31/03/2023 Estudio de la relevancia funcional de la organización de CXCR4 a nivel nanométrico durante los procesos de extravasación y migración intersticial linfocitaria (P20_00615) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 75.000,00 €
01/10/2021 01/04/2024 Replication and post-replication signalling pathways Regulating R-loop-associated Telomere instability in human cells – RteRloop (101027467) Comisión Europea (Europeo) 160.932,48 €
01/10/2021 31/01/2024 Regulation of DNA resection, DNA repair and genomic stability by cohesin in undifferentiated Caenorhabditis elegans germ cells – coDNAres (101023902) Comisión Europea (Europeo) 160.932,48 €
01/09/2021 28/02/2025 Understanding how formation of stress granules can impact in plant stress resistance (PID2020-119737GA-I00) Ministerio de Ciencia e Innovación (Nacional) 108.900,00 €
01/09/2021 31/08/2024 Ecología del estrés en saliva humana: asociación con estado de enfermedad (PID2020-118557GA-I00) Ministerio de Ciencia e Innovación (Nacional) 131.890,00 €
01/09/2021 31/12/2022 Cellular and Biophysical Approach to Understand the Cytokinemediated Regulation of the Lysosomal Hydrolytic Capacity - CytoLysoReg (101025429) Comisión Europea (Europeo) 115.288,32 €
12/05/2021 12/05/2024 Biointeractomica de la Reparacion del Daño en DNA en Condicines Homeostaticas y Patologicas DNA Damage (F. ARECES 21) Fundación Ramón Areces (Nacional) 112.000,00 €
01/06/2020 31/12/2023 Regulación de la Elongación de la Transcripción en Respuesta a Daño en el DNA (PID2019-104484GA-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 145.200,00 €
01/06/2020 31/12/2023 Mecanismos Moleculares Relacionados con el Control de la Calidad y la Degradación Post-ER de las Proteínas (PID2019-108564GB-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 108.900,00 €
01/06/2020 30/11/2023 Mecanismos de Inestabilidad Genómica Mediada por ARN y Reparación (PID2019-104270GB-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 484.000,00 €
01/06/2020 30/11/2023 Consecuencias para la Homeostasis Celular del Desequilibrio en la Reparación del DNA (PID2019-104195GB-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 338.800,00 €
01/02/2020 30/04/2022 Molecular Basis for Acute Hypoxia-Related Diseases: Understanding the Role of Cytochrome c in Respirasome Assembly and Functioning (US-1257019) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 80.000,00 €
01/02/2020 30/04/2022 Modificaciones de histonas y proteínas de unión a ARN en el origen de la inestabilidad genética (US-1258654) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 80.000,00 €
01/02/2020 31/01/2022 Unraveling the connection between centrosomes and the DNA damage response (US-1255532) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 80.000,00 €
01/02/2020 31/01/2022 Caracterización funcional y de los mecanismos de acción mediados por MOK en la neuroinflamación asociada a proteinopatías neurodegenerativas: Esclerosis Lateral Amiotrófica (ELA) y Enfermedad de Parkinson (US-1265227) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 30.000,00 €
01/01/2020 30/06/2023 Fuzzy Interactions between RNA Binding Proteins in Neurodegenerative Disorders (Fuzzy Disorders) (P18-FR-3487) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 125.500,00 €
01/01/2020 31/03/2023 Respuesta transcriptional en cis a la presencia de daño en el DNA (P18-FR-655) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 145.625,00 €
01/01/2020 31/01/2023 Nuclear physics developments for proton therapy: delivering the right effective dose to the right place (NucPhysPT) (P18-RT-1900) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 119.800,00 €
01/01/2020 31/12/2022 La Anemia de Fanconi y el daño endógeno (P18-RT-1271) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 119.652,00 €
01/01/2020 31/12/2022 Regulation of DNA break repair by the circadian clock (P18-RT-1204) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 137.011,00 €
16/09/2019 15/09/2022 Identificación del mecanismo molecular que regula la organización espacio-temporal de los receptores de uimioquinas y su relevancia funcional en el tráfico linfocitario. (RTI2018-101789-J-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 181.500,00 €
03/04/2019 30/04/2024 Caracterización funcional y de los mecanismos de acción mediados por la kinasa de señalización MOK en la neuroinflamación asociada a la Esclerosis Lateral Amiotrófica (ELA) (2019/FARECES/CROODVELT) Fundación Ramón Areces (Nacional) 105.762,00 €
03/04/2019 03/04/2022 Nuevas pistas sobre el síndrome de Aicardi-Goutières Syndrome, una conexión original con la reparación del ADN (2019/FARECES /PHUERTAS) Fundación Ramón Areces (Nacional) 126.652,00 €
01/01/2019 31/12/2022 Caracterización Funcional e Intervención de una Nueva Ruta de Señalización de la Neuroinflamación Mediada por Microglia en Esclerosis Lateral Amiotrófica (Ela) (RTI2018-098432-B-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 193.600,00 €
01/01/2019 30/09/2022 Fosforilaciones de ATM/Atr en Respuesta al Daño en el ADN Durante Meiosis (PGC2018-101099-B-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 105.875,00 €
01/01/2019 30/09/2022 Daño Endógeno del DNA en la Anemia de Fanconi (RTI2018-100692-B-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 121.000,00 €
01/01/2019 31/12/2021 Aproximaciones Estructurales y Funcionales a los Mecanismos Moleculares Dependientes de Citocromo C que Regulan la Actividad de las Chaperonas de Histonas Bajo Daño en el ADN (PGC2018-096049-B-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 190.575,00 €
01/10/2018 30/09/2020 Mechanistic analysis of DNA damage signaling and bypass upon replication of damaged DNA template in human cells (DNACHECK) (H2020-794054) Comisión Europea (Europeo) 170.121,60 €
15/04/2018 14/04/2019 Role and inmunotherapeutic potential of molecular chaperones in neurodegenerative amyloid disorders (RYC-2016-21372) Universidad de Sevilla (Local) 40.000,00 €
30/12/2016 31/12/2020 Transcription y Replication como Fuentes de Inestabilidad Genética (BFU2016-75058-P) Ministerio de Economía y Competitividad (Nacional) 484.000,00 €
30/12/2016 29/12/2019 Regulación de la Recombinación en el Contexto Celular (SAF2016-74855-P) Ministerio de Economía y Competitividad (Nacional) 242.000,00 €
01/09/2016 31/12/2019 Descubrimiento de antitumorales innovadores dirigidos contra dianas oncológicas: sistema topoisomerasa y regulación la respuesta inmune- INMUNOTOP (RTC-2016-4611-1) Ministerio de Economía, Industria y Competitividad (Nacional) 322.585,00 €
01/01/2016 30/06/2019 Disección de la Replicación Genomica Inicada Por R-Loops al Nivel Genético y Molecular (BFU2015-69183-P) Ministerio de Economía y Competitividad (Nacional) 177.870,00 €
01/01/2016 30/06/2019 Bases Estructurales de la Regulación Celular Mediada por Hur y Citocromo C (BFU2015-71017-P) Ministerio de Economía y Competitividad (Nacional) 213.444,00 €
01/12/2015 30/11/2021 R-loops as a major modulator of transcription-associated recombination and chromatin dynamics (TARLOOP) (2628/0721) Comisión Europea (Europeo) 2.312.500,00 €
07/04/2015 06/03/2017 Bases Moleculares de la Enfermedad: Biointeractómica de la Muerte Celular Programada (SUBPIVFRA/2015/015) Fundación Ramón Areces (Nacional) 117.200,00 €
01/01/2015 31/12/2018 Desarrollo de una terapia para el tratamiento de variantes genéticas de alfa-sinucleína en la enfermedad de parkinson (RTC-2015-3309-1) Ministerio de Economía y Competitividad (Nacional) 383.095,47 €
01/01/2015 31/12/2017 Sistemas nanoestructurados direccionados por el péptido intesinal vasoactivo (VIP) como alternativas para la detección y tratamiento de cáncer de próstata: caracterización preclínica (PI14/01600) Ministerio de Economía y Competitividad (Instituto de Carlos III) (Nacional) 83.490,00 €
01/01/2015 31/12/2017 RNA-DNA Hybrids as a source of genome instability in cancer (15-0098) Worldwide Cancer Research (Europeo) 214.620,00 €
30/01/2014 31/07/2019 Latencia de la Infección por VIH-1: Mecanismos Moleculares y Estrategias de Terapia Génica Mediante Nanopartículas Dirigidas (P12-BIO-1938) Consejería de Economía, Innovación y Ciencia (Autonómico) 273.894,00 €
30/01/2014 16/02/2019 Origen de la Inestabilidad Cromosómica Asociada a Defectos en Transcripción y Replicación (P12-BIO-1238) Consejería de Economía, Innovación y Ciencia (Autonómico) 273.894,00 €
30/01/2014 31/12/2017 Relación del Daño en Fase S y los Defectos de Segregación en Mitosis en los Síndromes Recesivos con Microcefalia (P12-BIO-515) Consejería de Economía, Innovación y Ciencia (Autonómico) 126.000,00 €
01/01/2014 30/06/2017 Regulación Cruzada Entre la Transcripción y la Estabilidad de los Mrnas: Influencia de la Cromatina y del Backtracking de la RNA Pol II (BFU2013-48643-C3-1-P) Ministerio de Economía y Competitividad (Nacional) 278.300,00 €
01/01/2014 30/06/2017 Inestabilidad Genómica Asociada a Transcripción e Híbridos DNA-RNA (BFU2013-42918-P) Ministerio de Economía y Competitividad (Nacional) 629.200,00 €
01/01/2014 31/12/2016 Regulación del Procesamiento de los Cortes de Doble Cadena en el ADN y su Implicación en el Desarrollo Tumoral (SAF2013-43255-P) Ministerio de Economía y Competitividad (Nacional) 157.300,00 €
26/03/2013 31/05/2018 Desarrollo Preclínico del Eje de Neuropéptidos VIP/Adnp como Agentes Modificadores de Actividad Biológica de Células Madres de Médula Ósea en el Modelo Experimental de Esclerosis Lateral Amiotrófica (P11-CTS-8161) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 172.367,75 €
26/03/2013 31/03/2018 Protección ante el Daño Celular Causado por la Luz Solar: Valoración de Nuevos Filtros UV (P11-CTS-7962) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 237.222,00 €
26/03/2013 30/09/2016 Bases Moleculares de Enfermedades Neurodegenerativas Ligadas a Acumulación Proteica: Papel de la Reparación de Roturas en el ADN (P11-CVI-7948) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 172.268,56 €
01/01/2013 31/12/2015 Desvelando Nuevas Redes de Proteínas que Interaccionan con el Citocromo C: Análisis Comparativo Estructural y Funcional (BFU2012-31670) Ministerio de Economía y Competitividad (Nacional) 219.960,00 €
01/01/2012 31/12/2016 Relevance of double strand break repair pathway choice in human disease and cancer (FP7-IDEAS-ERC-SG-LS2-278867) Comisión Europea (Europeo) 1.416.866,00 €
15/03/2011 30/06/2015 Nanotecnología como Plataforma de Desarrollo de Inmunoterapias Mediadas por Nanoparticulas Funcionalizadas con Péptido Intestinal Vasoactivo (VIP) en enfermedades inflamatorias Yautoinmunes: Proyecto Nanovip (P10-CTS-6928) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 234.030,00 €
01/01/2011 30/11/2014 Roturas de ADN Asociadas a Replicación y Reparación por Recombinación de Genomas Eucarióticos (BFU2010-16372) Ministerio de Ciencia e Innovación (Nacional) 834.900,00 €
01/01/2011 31/07/2014 Regulación Global de la Expresión Génica: Mecanismos Moleculares de la Elongación de la Transcripción en Eucariontes (BFU2010-21975-C03-03) Ministerio de Ciencia e Innovación (Nacional) 266.200,00 €
01/01/2011 31/12/2013 Modulación en el Contexto del Ciclo Celular del Tipo de Reparación de Cortes de Doble Cadena en el DNA en Eucariotas Superiores (SAF2010-14877) Ministerio de Ciencia e Innovación (Nacional) 181.500,00 €
01/01/2011 31/12/2013 Poliploidia Nuclear y Alteraciones Mitocondriales Relacionadas con la Homeostasis de Iones (BFU2010-21339) Ministerio de Ciencia e Innovación (Nacional) 108.900,00 €
03/02/2010 01/12/2013 Bases Genéticas y Moleculares del Origen de la Inestabilidad Genomica en Eucariotas (P09-CVI-4567) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 204.445,00 €
03/02/2010 03/02/2013 Nuevas Terapias Antiparasitarias: Uso de Neuropéptidos Endógenos (P09-CTS-4705) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 113.383,00 €
01/01/2010 31/12/2012 Bases estructurales, reconocimiento molecular y análisis evolutivo del citocromo C, una proteína bifuncional modificada post- tradiccionalmente (BFU2009-07190) Ministerio de Ciencia e Innovación (Nacional) 363.000,00 €
01/01/2010 31/12/2012 Estudio de la capacidad inmunoreguladora del péptido intestinal vasoactivo (VIP) sobre células madre derivadas de tejido adiposo (CMDA) en el modelo preclínico de esclerosis múltiple (PS09/02252) Ministerio de Ciencia e Innovación (Instituto de Salud Carlos III) (Nacional) 110.715,00 €
20/01/2009 20/01/2012 Síntesis y caracterización biológica de nanopartículas funcionalizadas con el péptido intestinal vasoactivo (Vip) como plataforma de medicamentos innovadores en cáncer de próstata: efectos inmunoreguladores y antitumorales (PI-0068/2008) Junta de Andalucía (Consejería de Salud) (Autonómico) 53.200,00 €
13/01/2009 31/12/2013 Búsqueda Estructural de Metaloproteínas Vegetales Capaces de Inhibir la Invasión Celular y Posterior Desarrollo del Parásito de la Malaria (P08-CVI-03876) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 259.923,68 €
13/01/2009 31/12/2013 ¿Nanomedicina?: Uso de Nanotubos de Carbón como Transportadores Multifunctionales de Medicina para el Tratamiento del Cáncer. (P08-CTS-04297) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 185.923,68 €
31/01/2008 31/12/2012 Regulación Transcripcional de los Genes Implicados en la Síntesis de Ribosomas: Relación con la Sensibilidad a Drogas Inmunosupresoras e Influencia del Proceso de Ensamblaje de Ribosomas (P07-CVI-02623) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 387.668,00 €
31/01/2008 31/12/2012 Regulación Post-Transcripcional de la Muerte Celular Programada (P07-CVI-02896) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 170.000,00 €
31/01/2008 30/11/2011 Genómica Funcional de la Interconexión Transcripción -Transporte de ARN (P07-CVI-02549) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 352.000,04 €
01/10/2007 09/12/2013 Inestabilidad genómica (CSD2007-00015) Ministerio de Educación y Ciencia (Nacional) 6.000.000,00 €
01/10/2007 30/09/2010 Estudio y desarrollo de aplicaciones, métodos, física y diseño de dispositivos para la generación de chorros capilares y producción de partículas, aerosoles y espumas micro y nanométricos (DPI2007-63559) Ministerio de Educación y Ciencia (Nacional) 435.358,00 €
13/04/2007 12/04/2010 Estudios inmunobiológicos y de degeneración neuronal parkinsoniana tras la inactivación génica de la biosíntesis (P06-CTS-01604) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico) 177.999,92 €
17/10/2006 30/12/2009 Efecto del péptido biactivo NAP en un modelo experimental de artritis reumatoide: regulación de los componentes inflamatorios y autoinmunes y estudio prospectivo terapeútico (PI061641) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional) 88.330,00 €
01/10/2006 30/09/2011 Bases genéticas y moleculares de la inestabilidad genómica y su relación con la biogénesis de los mRNPs de eucariotas (BFU2006-05260) Ministerio de Educación y Ciencia (Nacional) 757.339,00 €
01/10/2006 31/12/2009 Caracterización de proteínas y sustancias supresoras de los daños en el ADN debidas a la acción de la topoisomerasa I (BIO2006-08051) Ministerio de Educación y Ciencia (Nacional) 91.960,00 €
01/10/2006 30/09/2009 Análisis evolutivo y relación estructura-función del citocromo c y su equivalente metabólico, el citocromo c6, como inductores de muerte celular programada (BFU2006-01361) Ministerio de Educación y Ciencia (Nacional) 440.803,00 €
03/06/2006 02/06/2008 Evaluación y caracterización funcional del potencial adyuvante de la melatonina en la vacunación contra clostridium y chalmydophila en oveja (PTR1995-1011-OP) Ministerio de Educación y Ciencia (Nacional) 55.650,00 €
01/03/2006 28/02/2009 Bases genéticas y moleculares del origen de la inestabilidad genética en eucariotas (EXC/2005/CVI-624) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico) 163.000,00 €
01/03/2006 28/02/2009 Flow Focusing y Electro-Flow Focusing en Biomedicina y Biotecnología (EXC/2005/TEP-1190) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico) 143.000,00 €
23/12/2005 23/12/2008 Efectos inmunomoduladores del péptido bioactivo NAP, mecanismos de acción y evaluación terapéutica en la inflamación crónica: implicaciones en la esclerosis múltiple y la enfermedad de Crohn (PI052056) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional) 75.565,00 €
19/12/2005 19/12/2006 Estudio de los efectos del gen ADNP y del péptido bioactivo NAP en patologías con un componente inmunitario (SUVB. I.C.A.I.) Universidad Pontificia Comillas (ICAI) (Autonómico) 13.800,00 €
13/12/2004 13/12/2007 Análisis funcional de la biogénesis del ribosoma en saccharomyces cerevisiae (BFU2004-00252) Ministerio de Ciencia y Tecnología (Nacional) 131.100,00 €
15/10/2004 14/10/2006 Novel Flow Focusing technology to produce microencapsulated probiotic bacteria for the food sector (FLOCAP) (COOP-CT-2004-513144) Commission of the European Communities (Research Directorate-General) (Europeo) 139.277,60 €
28/11/2003 28/11/2006 Inmunoregulación de las células Natural Killer T (NK-T) por VIP: análisis funcional, mecanismos de acción y efecto sobre la patogénesis de la diabetes tipo 1 como modelo de enfermedad autoinmune Th1 (PI030359) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional) 51.060,00 €
15/11/2003 14/04/2007 Inestabilidad genética asociada a transcripción en eucariotas (SAF2003-00204) Ministerio de Ciencia y Tecnología (Nacional) 421.100,00 €
15/11/2003 15/11/2006 Aproximaciones genéticas y moleculares al estudio de la elongación transcripcional (BMC2003-07072-C03-01) Ministerio de Ciencia y Tecnología (Nacional) 124.500,00 €
15/11/2003 15/11/2006 Caracterización de genes de trichoderma harzianum implicados en protección de plantas y en antagonismo contra hongos patógenos (BIO2003-03679) Ministerio de Ciencia y Tecnología (Nacional) 143.750,00 €
15/11/2003 15/11/2006 Collision or progression: DNA replication fork traversal and RNAPII transcription termitation (BIO2003-07172) Ministerio de Ciencia y Tecnología (Nacional) 117.300,00 €
01/12/2002 01/12/2005 Neuroinmunoregulación de las células cebadas: mecanismos de acción y efectos biológicos de la melatonina y el VIP (BFI2002-03544) Ministerio de Ciencia y Tecnología (Nacional) 60.950,00 €
28/12/2001 27/12/2004 Saccharomyces cerevisiae como modelo eucariótico para el estudio genómico y proteómico de la respuesta celular al estres (GEN2001-4707-C08-02) Ministerio de Ciencia y Tecnología (Nacional) 141.450,00 €
28/12/2001 27/12/2004 Análisis bioquímico y genético de la biogénesis del ribosoma en saccharomyces cerevisiae (BMC2001-2660) Ministerio de Ciencia y Tecnología (Nacional) 92.615,96 €
20/12/2000 20/12/2003 Recombinación entre secuencias repetidas e inestabilidad genética en saccharomyces cerevisiae: un modelo funcional eucarionte (BMC2000-0439) Ministerio de Ciencia y Tecnología (Nacional) 192.695,91 €
20/12/2000 20/12/2003 Análisis genético de la elongación transcripcional de saccharomyces cerevisiae: un modelo eucarionte (BMC2000-1128-C02-01) Ministerio de Ciencia y Tecnología (Nacional) 107.701,37 €
01/11/2000 30/04/2002 Caracterización de los efectos antiinflamatorios de la Neurohormona melatonina: Estudio in vitro e in vivo. (PTR-1995-0451-OP) Ministerio de Educación, Cultura y Deporte (Nacional) 54.265,38 €
01/10/1997 31/07/2000 EUROPEAN NETWORK FOR THE FUNCTIONAL ANALYSIS OF YEAST GENES DISCOVERED BY SYSTEMATIC DNA SEGUENCING. PHASE 2 (BIO4-CT97-2294) 70.000,00 €
01/12/1995 31/10/1998 EUROPEAN NETWORK FOR THE FUNCTIONAL ANALYSIS OF YEAST GENES DISCOVERED BY SYSTEMATIC DNA SEQUENCING. PHASE 1 EUROFAN (BIO4-CT95-0080) 18.000,00 €

Contratos

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
27/10/2023 26/10/2026 Metabolómica de Enfermedades Neurodegenerativas con Acumulación Cerebral de Hierro mediante Resonancia Magnética Nuclear (ENACH Metabolomics) (4977/2038) ENACH Asociación (Desconocido)
01/09/2017 31/08/2018 Exploring the Molecular Mechanism of Lurbinectedin as an Antitumoral Target in BRCA2-/-HUMAN CELL LINES (3129/0721) PharmaMar, S.A. (Desconocido)
01/11/2016 30/09/2017 VIPCURE: The development of a Therapeutic Viral Vector Vaccine for the treatment of Amyotrophic Lateral Sclerosis (2901/0013) Amarna Therapeutics, S.L. (Desconocido)
29/12/2014 28/12/2015 Saccharomyces cerevisiae recombinant strains for dodecanol production. (2399/0747) Abengoa Bioenergía Nuevas Tecnologías (Desconocido)
01/06/2014 31/05/2015 Modificación Genética de microorganismos para producción de Biofuel (2287/0721) ABENGOA RESEARCH S.L. (Desconocido)
01/05/2014 30/04/2017 Mechanism of action of Yondelis as an R-loop-mediated genome instability inducer (2213/0721) Pharma Mar, S.A. (Desconocido)
01/01/2014 31/12/2017 Towards a therapeutic vaccine for Amyotrophic lateral sclerosis: ALSVac (2106/0013) Amarna Therapeutics, S.L. (Desconocido)
01/01/2010 31/12/2010 Diseño e implantación de Programas de I+D+I estratégicos en Terapia Génica, Celular y Nanomedicina. Área Desarrollo de la Producción Científica. Fundación Pública Andaluza Progreso y Salud. Consejería de Salud. Junta de Andalucía. (0669/0013) Fundación Progreso y Salud (Desconocido)
01/10/2009 31/12/2009 Realización de pruebas de concepto para el estudio de la actividad inmunomoduladora del condroítin sulfato. (0541/0013) BIOIBÉRICA, S.A. (Desconocido)
30/06/2009 30/06/2010 Biomarcadores. Desarrollo y aplicaciones en agroalimentación y sanidad. (Prórroga) (SI-001/09) Newbiotechnic, S.A. (Desconocido)
30/06/2008 30/06/2009 Construcción de genotecas de anticuerpos de cadena sencilla (SI-008/09) Newbiotechnic, S.A. (Desconocido)
24/09/2007 24/09/2008 Diseño e implantación de programas y proyectos de innovación e investigación biomédica del Sistema Sanitario Público de Andalucia (0014/0013) Fundación Progreso y Salud (Desconocido)
30/06/2007 30/06/2008 Construcción de genotecas de anticuerpos de cadena sencilla (SI-079/07) Newbiotechnic, S.A. (Desconocido)
30/06/2006 30/06/2007 Construcción de genotecas de anticuerpos de cadena sencilla (SI-003/07) Newbiotechnic, S.A. (Desconocido)
16/12/2005 16/12/2007 Desarrollar sistemas de expresión de múltiples genes regulada por estrógenos. Desarrollo de LYTAG en levaduras para identificaicón de interacciones proteína-proteína en levaduras. Desarrollo de un plásmido para coexpresar hasta cuatro proteínas en levaduras (OG-138/05) Biomedal, S.L. (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/01/2023 31/12/2025 Unidad de Excelencia “María de Maeztu”. Centro Andaluz de Biología Molecular y Medicina Regenerativa (QUAL21 007 USE) Junta de Andalucía (Consejería de Transformación Económica, Industria, Conocimiento y Universidades) (Autonómico) 668.868,75 €
01/01/2017 31/12/2019 Embo yip Huertas (EMBO YIP HUERTAS) Embo (Europeo) 15.000,00 €
01/10/2015 30/09/2016 Taller FEBS sobre Biointeractómica: De las interacciones bimoleculares a las redes (BFU2015-63206-CIN) Ministerio de Economía y Competitividad (Nacional) 10.000,00 €
29/08/2013 03/09/2013 Ayuda para asistencia a 26th International Conference on Yeast Genetics and Molecular Biology (PP2013-1682) Universidad de Sevilla (Local) 600,00 €
01/07/2011 30/06/2013 Mecanismos de recombinación e inestabilidad genómica (BFU2011-14518-E) Ministerio de Ciencia e Innovación (Nacional) 15.000,00 €
01/01/2008 31/12/2008 Are there natural autoepitope-mimiching melecules with cytotoxic activity, capable of preventing autoimmune disease? A basic biological question with strong biotechnological implications (SAF2007-29418-E) Ministerio de Educación y Ciencia (Nacional) 29.300,00 €
01/12/2007 30/11/2010 Vigilancia del ARN nuclear en la expresión génica (BFU2007-28647-E) Ministerio de Educación y Ciencia (Nacional) 219.000,00 €
01/01/2007 31/12/2008 RNA Helicases: understanding their function during ribosome biogenesis (HF2006-0153) Ministerio de Educación y Ciencia (Nacional) 11.050,00 €
15/11/2006 17/11/2006 Salud y calidad de vida ¿Que podemos aprender de nuestros científicos) I Jornadas Andaluzas de Ciencias y Sociedad 2006 desde la Universidad de Sevilla (PP2005-01-23) Universidad de Sevilla (Local) 1.400,00 €
06/03/2006 06/08/2006 Estudio prospectivo del uso terapéutico como inmunomodulador del péptido bioactivo NAP (OTRI/05-FP02) Universidad de Sevilla(Oficina de Transferencia de Resultados de Investigación) (Local) 1.600,00 €
24/05/2004 24/05/2005 European Research Conference on Gene Transcription in Yeast (BIO2002-12861-E) Ministerio de Educación y Ciencia (Nacional) 10.800,00 €

Redes de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/06/2023 31/05/2025 Inestabilidad Genómica (RED2022-134164-T) Ministerio de Ciencia e Innovación (Nacional) 20.000,00 €
01/01/2020 30/10/2022 Inestabilidad Genómica (RED2018-102372-T) Ministerio de Ciencia, Innovación y Universidades (Nacional) 22.000,00 €
01/07/2017 31/12/2019 Inestabilidad Genomica (BFU2016-81796-REDC) Ministerio de Economía y Competitividad (Nacional) 41.500,00 €
01/12/2014 30/11/2016 Inestabilidad Genómica (BFU2014-51672-REDC) Ministerio de Economía y Competitividad (Nacional) 39.000,00 €

Infraestructura

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
28/12/2020 28/12/2022 Renovación de equipamiento científico en biología molecular y celular de CABIMER (IE19_101_USE) Junta de Andalucía - Consejería de Transformación Económica, Industria, Conocimiento y Universidades (Autonómico) 229.031,00 €
01/01/2019 31/12/2021 Equipo de secuenciación masiva para la Unidad de Genómica de CABIMER (EQC2019-005817-P) Ministerio de Ciencia, Innovación y Universidades - Agencia Estatal de Investigación (Nacional) 825.654,07 €
01/06/2018 31/03/2022 Mejora de infraestructura científica y actividades de transferencia y difusión de CABIMER para la adquisición del sello Maria Maeztu (SOMM17/6112/USE) Junta de Andalucía - Consejería de Conocimiento, Investigación y Universidad (Europeo) 968.640,38 €
01/01/2018 31/03/2021 Equipamiento para Biología Computacional y Genómica de CABIMER (EQC2018-004672-P) Ministerio de Ciencia, Innovación y Universidades - Agencia Estatal de Investigación (Nacional) 372.247,00 €
01/01/2016 30/06/2018 Secuenciador masivo de ácidos nucléicos para servicio de genómica (UNSE15-CE-2856) Ministerio de Economía y Competitividad (Europeo) 205.004,80 €
01/01/2010 31/12/2012 Actualización y ampliación de la unidad de genómica del Cabimer. Universidad de Sevilla (UNSE10-1E-433) Ministerio de Ciencia e Innovación (Europeo) 304.080,00 €