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Ver Investigador - - Prisma - Unidad de Bibliometría

Ignacio Bejarano Hernando

Profesor Titular de Universidad
ibejarano@us.es
Área de conocimiento: Bioquímica y Biología Molecular
Departamento: Bioquímica Médica y Biología Molecular e Inmunología
Grupo: NeuroInmunoEndocrinología Molecular - CTS-160 (Universidad de Sevilla)

Investiga en

Palabras clave
Líneas de investigación
Resumen
Tipo Año Título Fuente
Artículo2024 Anti-obesogenic effect of lupin-derived protein hydrolysate through modulation of adiposopathy, insulin resistance and gut dysbiosis in a diet-induced obese mouse BIOMEDICINE & PHARMACOTHERAPY
Artículo2024 Melatonin synergistically potentiates the effect of methylprednisolone on reducing neuroinflammation in the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis JOURNAL OF AUTOIMMUNITY
Resumen congreso2023 Combination therapy with melatonin and methylprednisolone synergistically prevents the development of experimental autoimmune encephalomyelitis (EAE) through the control of neuroinflammation MULTIPLE SCLEROSIS
Revisión2023 The Impressive Anti-Inflammatory Activity of Cerium Oxide Nanoparticles: More than Redox? NANOMATERIALS
Artículo2022 A lupin (Lupinus angustifolius) protein hydrolysate exerts anxiolytic-like effects in western diet-fed apoE−/− mice INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2022 Bioactive Peptides from Lupin (Lupinus angustifolius) Prevent the Early Stages of Atherosclerosis in Western Diet-Fed ApoE–/– Mice JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2022 GPX3 overexpression in cumulus cells entails a poor prognosis for uterine implantation of morphotype a embryos Biology
Artículo2021 Anxiolytic-Like Effects of Lupinus angustifolious Protein Hydrolysates in Alzheimer Model Mice Proceedings (MDPI)
Artículo2021 Lupinus angustifolius protein hydrolysates reduce abdominal adiposity and ameliorate metabolic associated fatty liver disease (Mafld) in western diet fed-apoe−/− mice ANTIOXIDANTS
Artículo2021 Safety and efficacy of a beverage containing lupine protein hydrolysates on the immune, oxidative and lipid status in healthy subjects: an intervention study (the lupine-1 trial). MOLECULAR NUTRITION & FOOD RESEARCH
Artículo2020 Immunomodulatory and antioxidant properties of wheat gluten protein hydrolysates in human peripheral blood mononuclear cells NUTRIENTS
Resumen congreso2020 Melatonin reduces disability in experimental autoimmune encephalomyelitis by impairing immune cells migration and entry into the CNS MULTIPLE SCLEROSIS
Artículo2020 Pt(II) and Pd(II) complexes with a thiazoline derivative ligand: Synthesis, structural characterization, antiproliferative activity and evaluation of pro-apoptotic ability in tumor cell lines HT-29 and U-937 JOURNAL OF INORGANIC BIOCHEMISTRY
Artículo2019 Impact of Melatonin Supplementation in Women with Unexplained Infertility Undergoing Fertility Treatment ANTIOXIDANTS
Revisión2018 Apoptosis Is a Demanding Selective Tool During the Development of Fetal Male Germ Cells FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Artículo2018 Melatonin increases the effect of 5-fluorouracil-based chemotherapy in human colorectal adenocarcinoma cells in vitro MOLECULAR AND CELLULAR BIOCHEMISTRY
Artículo2017 Melatonin diminishes oxidative damage in sperm cells, improving assisted reproductive techniques TURKISH JOURNAL OF BIOLOGY
Artículo2017 Participation of MT3 melatonin receptors in the synergistic effect of melatonin on cytotoxic and apoptotic actions evoked by chemotherapeutics CANCER CHEMOTHERAPY AND PHARMACOLOGY
Artículo2017 Salud en tu piel. A las puertas del verano Viceversa: UEx & empresa
Artículo2016 Autophagy-related proteins are functionally active in human spermatozoa and may be involved in the regulation of cell survival and motility Scientific reports
Artículo2015 Cerium oxide nanoparticles, combining antioxidant and UV shielding properties, prevent UV-induced cell damage and mutagenesis NANOSCALE
Artículo2015 Effect of non-alcohol beer on anxiety: Relationship of 5-HIAA NEUROCHEMICAL JOURNAL
Artículo2015 Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid MITOCHONDRION
Artículo2015 Quercus Suber L. Cork Extracts Induce Apoptosis in Human Myeloid Leukaemia HL-60 Cells PHYTOTHERAPY RESEARCH
Artículo2015 Subscapular and triceps skinfolds reference values of Hispanic American children and adolescents and their comparison with the reference of Centers for Disease Control and Prevention (CDC) NUTRICION HOSPITALARIA
Ponencia2014 Cerium oxide nanoparticles as multitasking UV-B shields ACTA PHYSIOLOGICA
Ponencia2014 Effect of chemotherapics of new pyrazole-based platinum (II) chloride complexes in cancer cells ACTA PHYSIOLOGICA
Ponencia2014 Effect of non-alcoholic beer on anxiety: relationship on 5-HIAA ACTA PHYSIOLOGICA
Artículo2014 Exogenous melatonin supplementation prevents oxidative stress-evoked DNA damage in human spermatozoa JOURNAL OF PINEAL RESEARCH
Ponencia2014 Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in human cervical cancer hela cells ACTA PHYSIOLOGICA
Ponencia2014 Melatonin promotes bax sequestration to mitochondria protecting cell from apoptosis via the lox metabolite 5-hete ACTA PHYSIOLOGICA
Artículo2012 Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells JOURNAL OF PINEAL RESEARCH
Artículo2012 Targeting mitochondria by alpha-tocopheryl succinate kills neuroblastoma cells irrespective of MycN oncogene expression CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2011 High endogenous melatonin concentrations enhance sperm quality and short-term in vitro exposure to melatonin improves aspects of sperm motility JOURNAL OF PINEAL RESEARCH
Artículo2011 Melatonin enhances hydrogen peroxide-induced apoptosis in human promyelocytic leukaemia HL-60 cells MOLECULAR AND CELLULAR BIOCHEMISTRY
Artículo2011 Melatonin is able to delay endoplasmic reticulum stress-induced apoptosis in leukocytes from elderly humans Age
Artículo2011 Melatonin protects human spermatozoa from apoptosis via melatonin receptor- and extracellular signal-regulated kinase-mediated pathways FERTILITY AND STERILITY
Artículo2011 Pro-Oxidant Effect of Melatonin in Tumour Leucocytes: Relation with its Cytotoxic and Pro-Apoptotic Effects BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2011 Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions JOURNAL OF PINEAL RESEARCH
Artículo2010 Caspase-3 and-9 are activated in human myeloid HL-60 cells by calcium signal MOLECULAR AND CELLULAR BIOCHEMISTRY
Editorial2010 Melatonin as a potential tool against oxidative damage and apoptosis in ejaculated human spermatozoa FERTILITY AND STERILITY
Artículo2010 Melatonin Counteracts Alterations in Oxidative Metabolism and Cell Viability Induced by Intracellular Calcium Overload in Human Leucocytes: Changes with Age BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2010 Melatonin Reduces Apoptosis Induced by Calcium Signaling in Human Leukocytes: Evidence for the Involvement of Mitochondria and Bax Activation JOURNAL OF MEMBRANE BIOLOGY
Revisión2010 Oxidative Stress-Induced Caspases are Regulated in Human Myeloid HL-60 Cells by Calcium Signal CURRENT SIGNAL TRANSDUCTION THERAPY
Artículo2010 The correlation between urinary 5-hydroxyindoleacetic acid and sperm quality in infertile men and rotating shift workers REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
Artículo2009 Melatonin and Tryptophan Affect the Activity-Rest Rhythm, Core and Peripheral Temperatures, and Interleukin Levels in the Ringdove: Changes With Age JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
Artículo2009 Melatonin and tryptophan counteract lipid peroxidation and modulate superoxide dismutase activity in ringdove heterophils in vivo. Effect of antigen-induced activation and age Age
Artículo2009 Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells JOURNAL OF PINEAL RESEARCH
Artículo2009 Reduced levels of intracellular calcium releasing in spermatozoa from asthenozoospermic patients REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
Artículo2009 Relationship between Caspase Activity and Apoptotic Markers in Human Sperm in Response to Hydrogen Peroxide and Progesterone JOURNAL OF REPRODUCTION AND DEVELOPMENT
Artículo2009 Role of calcium signals on hydrogen peroxide-induced apoptosis in human myeloid HL-60 cells International Journal of Biomedical Science
Artículo2009 Selenium Modulates Oxidative Stress-Induced Cell Apoptosis in Human Myeloid HL-60 Cells Through Regulation of Calcium Release and Caspase-3 and-9 Activities JOURNAL OF MEMBRANE BIOLOGY
Artículo2008 Caspase 3 activation in human spermatozoa in response to hydrogen peroxide and progesterone FERTILITY AND STERILITY
Artículo2008 Role of intracellular calcium on hydrogen peroxide-induced apoptosis in rat pancreatic acinar AR42J cells JOURNAL OF APPLIED BIOMEDICINE
Artículo2007 Hydrogen peroxide increases the phagocytic function of human neutrophils by calcium mobilisation MOLECULAR AND CELLULAR BIOCHEMISTRY
Efecto de la melatonina sobre la apoptosis inducida por especies reactivas de oxígeno y señal de calcio en la línea celular leucémica humana hl-60 (2011)
Dirigida por: José Antonio Pariente Llanos, Ana Beatriz Rodríguez Moratinos
Tesis dirigidas/tutorizadas:4
Fecha lectura Título Rol
22/11/2019 Papel de las proteínas de choque térmico (Heat Shock Proteins, HSP) en la apoptosis Director/a
25/09/2017 Papel de la melatonina en el estado oxidativo del líquido folicular y su relación con la calidad de los oocitos en mujeres con problemas de fertilidad Director/a
04/07/2017 Melatonina como agente coadyuvante de quimioterapeuticos en estudios in vitro Director/a
26/01/2016 Melatonina y calidad espermática: estudio "in vivo" e "in vitro" Director/a

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
27/10/2021 26/10/2023 Responsable Valoración de los efectos combinados de biopéptidos de lupino y melatonina en la obesidad y la enfermedad del hígado graso asociada a la disfunción metabólica (PEMP-0085-2020) Fundación Progreso y Salud (Autonómico)
01/12/2022 30/11/2024 Investigador/a Reutilizar y valorar la fracción orgánica del alperujo mediante el estudio de la bioactividad de sus hidrolizados proteicos en los componentes clave del síndrome metabólico (TED2021-131108B-I00) Ministerio de Ciencia e Innovación (Nacional)
01/12/2021 31/05/2024 Investigador/a Diseño Eficiente de la Iluminación Biodinámica para Promover el Ritmo Circadiano en instalaciones hospitalarias (PDC2021-120807-I00) Ministerio de Ciencia e Innovación (Nacional)
01/09/2021 31/08/2025 Investigador/a Iluminación biodinámica de amplio espectro para la cronoregulación biológica y la neutralización de patógenos en centros hospitalarios (PID2020-117563RB-I00) Ministerio de Ciencia e Innovación (Nacional)
01/02/2023 31/01/2026 Investigador/a Evaluación de la leguminosa costera Retama monosperma (L.) Boiss. Como nueva fuente proteica en alimentación animal (RETFEED) (PROYEXCEL_00708) Junta de Andalucía (Consejería de Transformación Económica, Industria, Conocimiento y Universidades) (Autonómico)
01/09/2023 31/08/2026 Investigador/a Estudio del efecto de una bebida fermentada rica en péptidos bioactivos a partir de subproductos vegetales en los componentes principales del síndrome metabólico (PID2022-137792OB-I00) Ministerio de Ciencia e Innovación (Nacional)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/09/2022 31/08/2023 Investigador/a Evaluation of the lipid-lowering effects of phenolic complex derived from olive oil (4588/0401) University of Milan, Dpto. of Pharmaceutical Sciences (Desconocido)
09/05/2024 08/07/2025 Investigador/a Analysis of metabolic effects of innovative phytocomplexes (5133/0401) University of Milan - Dpto. of Pharmaceutical Sciences (Desconocido)
09/05/2024 08/12/2024 Investigador/a Analysis of pre-and pro-biotics treatment in metabolic markers (5138/0401) University College Cork (Desconocido)
El investigador no tiene ningún resultado de investigación asociado