BQENV - Prisma - Unidad de Bibliometría

BIOQUIMICA DEL ENVEJECIMIENTO - BIO-158 (BQENV)

Tipo de colectivo: Grupo de investigación
Estado: Grupo definitivo
Ámbito: Andalucía
Instituciones: Universidad de Sevilla
Fecha de creación: 01/01/1995

Investiga en

Tipo Año Título Fuente
Artículo2024 Comparing fermented food and vitamin E on exercise-mediated Nrf2/ARE activation in middle-aged/ elderly: A randomized, double-blind clinical study Functional Food Science
Artículo2024 Gut-first Parkinson's disease is encoded by gut dysbiome Molecular Neurodegeneration
Artículo2024 Neutrophil-lymphocyte ratio and update conclusions from a 2-year double-blind rct testing fermented papaya preparation in healthy middle-aged/elderly subjects Functional Food Science
Artículo2023 “Farmaling”: Implementación y adaptación de una plataforma virtual de simulación para la docencia de Biología Molecular y Biotecnología RESCIFAR Revista Española de Ciencias Farmacéuticas
Capítulo2023 Anti-aging and rejuvenation based on stem cell therapy Emerging Anti-Aging Strategies
Capítulo2023 Basic pathways and targets for anti-aging intervention Anti-Aging Pharmacology
Artículo2023 Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria. GUT
Artículo2023 Instagram como herramienta de aprendizaje en Fisiología: @fisiofarma_us RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2023 Interim report from a 2-year double-blind RCT testing fermented papaya preparation on immune enhancement, endothelial health and QOL in elderly adults Functional Foods in Health and Disease
Artículo2023 Irisin enhance longevity by boosting SIRT1, AMPK, Autophagy and Telomerase. Expert reviews in molecular medicine
Revisión2023 Natural compounds as integrative therapy for liver protection against inflammatory and carcinogenic mechanisms: from induction to molecular biology advancement Current Molecular Medicine
Capítulo2023 Protein kinase modulation for anti-aging intervention Anti-Aging Pharmacology
Artículo2023 Relationship between insulin-biochemical resistance levels and the degree of depression and anxiety in patients from Honduras INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES
Revisión2023 The Emerging Role of Senotherapy in Cancer: A Comprehensive Review Clinics and Practice
Resumen congreso2022 @Fisiofarma_us outreach activity: a novel way to learn physiology at the University of Seville EDULEARN22 Proceedings: 14th International Conference on Education and New Learning Technologies : July 4th-6th, 2022
Artículo2022 Alteraciones fisiológicas en los transtornos de la conducta alimentaria RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2022 Anti-inflammatory effect of Phytomarine R-L compound against lipopolysaccharide- induced pulmonary injury in BALB/c mice Functional Foods in Health and Disease
Resumen congreso2022 Could ‘"Instagram stories" improve physiology skills?: An experience in Pharmacy and Optics degree EDULEARN22 Proceedings: 14th International Conference on Education and New Learning Technologies : July 4th-6th, 2022
Resumen congreso2022 Outreach activities on instagram improve educational and physiology competencies: relationship with the course of the enrolled degree ICERI 2022: 15TH ANNUAL INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION
Artículo2022 Selective blood-brain barrier permeabilisation of brain metastases by a type-1 receptor selective tumour necrosis factor mutein. NEURO-ONCOLOGY
Artículo2022 The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma BIOMED RESEARCH INTERNATIONAL
Resumen congreso2022 Using instagram to increase university educational skills. The professors’ point of view ICERI 2022: 15TH ANNUAL INTERNATIONAL CONFERENCE OF EDUCATION, RESEARCH AND INNOVATION
Artículo2021 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). AUTOPHAGY
Capítulo2021 Gut stem cells: Interplay with immune system, microbiota, and aging Stem Cells and Aging
Capítulo2021 Hydroxytyrosol, olive oil, and use in aging Olives and olive oil in health and disease prevention (Second Edition)
Ponencia2021 Incorporation of the mindfulness practice to improve university students’ academic performance EduLearn 21 Proceedings: 13th International Conference on Education and New Learning Technologies Online Conference. 5-6 July, 2021.
Revisión2021 The neuromicrobiology of Parkinson's disease: a unifying theory AGEING RESEARCH REVIEWS
Artículo2020 Effect of age and lipoperoxidation in rat and human adipose tissue-derived stem cells OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
Artículo2020 Effects on goal directed behavior and habit in two animal models of Parkinson's disease NEUROBIOLOGY OF LEARNING AND MEMORY
Capítulo2020 Elaboración de un folleto-tríptico sobre aspectos relevantes de cada una de las asignaturas impartidas por el departamento de fisiología Evaluación e innovación en educación superior e investigación
Revisión2020 Map kinase signaling as therapeutic target for neurodegeneration PHARMACOLOGICAL RESEARCH
Revisión2020 Oral microbiota and Alzheimer's disease: Do all roads lead to Rome? PHARMACOLOGICAL RESEARCH
Revisión2020 Rosmarinus officinalis l. (rosemary): an ancient plant with uses in personal healthcare and cosmetics Cosmetics
Artículo2019 Adipose-derived stem cells decreased microglia activation and protected dopaminergic loss in rat lipopolysaccharide model JOURNAL OF CELLULAR PHYSIOLOGY
Revisión2019 Advantages and disadvantages of apoptosis in the aging process ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Artículo2019 Bee Products: Royal Jelly and Propolis NONVITAMIN AND NONMINERAL NUTRITIONAL SUPPLEMENTS
Revisión2019 Dysregulation of the Hippo pathway signaling in aging and cancer PHARMACOLOGICAL RESEARCH
Resumen congreso2019 Elaboración de un tríptico sobre aspectos relevantes de las asignaturas impartidas por el departamento de fisiología de la Universidad de Sevilla Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Revisión2019 Hydroxytyrosol protects from aging process via AMPK and autophagy; a review of its effects on cancer, metabolic syndrome, osteoporosis, immune-mediated and neurodegenerative diseases PHARMACOLOGICAL RESEARCH
Revisión2019 Phosphodiesterase inhibitors say NO to Alzheimer's disease FOOD AND CHEMICAL TOXICOLOGY
Artículo2019 Physical exercise and myokines APPROACHES TO AGING CONTROL
Revisión2019 Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders PHARMACOLOGICAL RESEARCH
Artículo2019 Targeting pro-senescence mitogen activated protein kinase (Mapk) enzymes with bioactive natural compounds FOOD AND CHEMICAL TOXICOLOGY
Revisión2019 Targeting STATs in neuroinflammation: The road less traveled! PHARMACOLOGICAL RESEARCH
Artículo2019 Uric acid enhances longevity and endurance and protects the brain against ischemia NEUROBIOLOGY OF AGING
Revisión2018 Apigenin as neuroprotective agent: Of mice and men PHARMACOLOGICAL RESEARCH
Artículo2018 Cell tracking, survival, and differentiation capacity of adipose-derived stem cells after engraftment in rat tissue JOURNAL OF CELLULAR PHYSIOLOGY
Editorial2018 Current advances in pharmacotherapy and drug design against inflammatory-related pathologies CURRENT PHARMACEUTICAL DESIGN
Artículo2018 Intrathecal Injection of miR-133b-3p or miR-143-3p Prevents the Development of Persistent Cold and Mechanical Allodynia Following a Peripheral Nerve Injury in Rats NEUROSCIENCE
Revisión2018 Role of Melatonin in the Inflammatory Process and its Therapeutic Potential CURRENT PHARMACEUTICAL DESIGN
Revisión2018 Signaling Pathways in Inflammation and Anti-inflammatory Therapies CURRENT PHARMACEUTICAL DESIGN
Artículo2018 Targeting ERK signaling pathway by polyphenols as novel therapeutic strategy for neurodegeneration FOOD AND CHEMICAL TOXICOLOGY
Revisión2018 Targeting mTORs by omega-3 fatty acids: A possible novel therapeutic strategy for neurodegeneration? PHARMACOLOGICAL RESEARCH
Artículo2017 Aging and Oxidative Stress Decrease Pineal Elongation Factor 2: In Vivo Protective Effect of Melatonin in Young Rats Treated With Cumene Hydroperoxide JOURNAL OF CELLULAR BIOCHEMISTRY
Revisión2017 Application of Kinase Inhibitors for Anti-aging Intervention CURRENT PHARMACEUTICAL DESIGN
Artículo2017 Effect of VBC-1814/7J, a poly-phytocompound, on a non-infectious model of pharyngitis EXPERIMENTAL AND THERAPEUTIC MEDICINE
Artículo2017 Immunolocalization of Substance P and NK-1 Receptor in ADIPOSE Stem Cells JOURNAL OF CELLULAR BIOCHEMISTRY
Resumen congreso2017 Opinión del alumnado respecto al uso de aplicaciones para teléfonos móviles para la realización de evaluaciones Evaluación de la Calidad de la Investigación y de la Educación Superior: Libro de resúmenes XIV FECIES
Resumen congreso2017 Rendimiento académico del alumnado al utilizar nuevas tecnologías para evaluar las competencias en un laboratorio de prácticas Evaluación de la Calidad de la Investigación y de la Educación Superior: Libro de resúmenes XIV FECIES
Artículo2016 Beneficial effect of refined red palm oil on lipid peroxidation and monocyte tissue factor in HCV-related liver disease: a randomized controlled study HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
Artículo2016 Chronic stress alters the expression levels of longevity-related genes in the rat hippocampus NEUROCHEMISTRY INTERNATIONAL
Artículo2016 Hialuronic acid in sking aging Medicina Antienvejecimiento
Artículo2016 Time and dose dependent effects of oxidative stress induced by cumene hydroperoxide in neuronal excitability of rat motor cortex neurons NEUROTOXICOLOGY
Artículo2015 Advanced therapy medicinal products: Gene therapy Pharmaceuticals Policy and Law
Editorial2015 Current Advances in Biochemistry, Medicinal Chemistry and Drug Development Strategies for Age-Related Neurodegenerative Diseases CURRENT TOPICS IN MEDICINAL CHEMISTRY
Revisión2015 Endogenous opioid. A review APPROACHES TO AGING CONTROL
Capítulo2015 Medio ambiente y envejecimiento Innovación en la gestión e investigación ambiental
Artículo2015 Na+-dependent and Na+-independent betaine transport across the apical membrane of rat renal epithelium BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Artículo2015 Oxidative stress induced by cumene hydroperoxide evokes changes in neuronal excitability of rat motor cortex neurons NEUROSCIENCE
Artículo2015 Synergistic Deleterious Effect of Chronic Stress and Sodium Azide in the Mouse Hippocampus CHEMICAL RESEARCH IN TOXICOLOGY
Artículo2015 Treatment with mesenchymal stem cells in an animal model of parkinson's disease APPROACHES TO AGING CONTROL
Artículo2014 A Double-Blind, RCT Testing Beneficial Modulation of BDNF in Middle-Aged, Life Style-Stressed Subjects: A Clue to Brain Protection? JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Artículo2014 Chronic stress as a risk factor for Alzheimer's disease REVIEWS IN THE NEUROSCIENCES
Artículo2014 Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation JOURNAL OF NEUROINFLAMMATION
Ponencia2014 Effects of aging and oxidative stress on elongation factor-2 in the pineal gland and its protection by melatonin ACTA PHYSIOLOGICA
Artículo2014 Elongation factor 2 diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative Stress conditions FREE RADICAL BIOLOGY AND MEDICINE
Artículo2014 Experimental Evidence of Effectiveness of VBC-1814/7J, a Poly-Phytocompound, on Inflammatory and Virological Changes in an Influenza-Model. International Medical Journal
Revisión2014 Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
Ponencia2014 Transport of betaine across the apical membrane of rat renal epithelium ACTA PHYSIOLOGICA
Artículo2013 Molecular control of the amount, subcellular location, and activity state of translation elongation factor 2 in neurons experiencing stress FREE RADICAL BIOLOGY AND MEDICINE
Capítulo2012 Assessment of the general oxidant status of individuals in non-invasive samples Oxidative Stress - Molecular Mechanisms and Biological Effects
Artículo2012 Folic acid supplementation: some practical aspects APPROACHES TO AGING CONTROL
Artículo2012 In vitro and in vivo protection by melatonin against the decline of elongation factor-2 caused by lipid peroxidation: preservation of protein synthesis JOURNAL OF PINEAL RESEARCH
Artículo2012 Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system NEUROTOXICOLOGY
Artículo2012 Potential use of adipose tissue stem cells in the control of aging APPROACHES TO AGING CONTROL
Artículo2011 Effect of aging and oxidative stress on elongation factor-2 in hypothalamus and hypophysis MECHANISMS OF AGEING AND DEVELOPMENT
Artículo2011 Incorporación de casos clínicos para la mejora de la enseñanza de Fisiopatología Revista de Enseñanza Universitaria
Artículo2011 Inflammatory animal models for parkinson's disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons ISRN Neurology
Revisión2011 Peripheral Inflammation Increases the Damage in Animal Models of Nigrostriatal Dopaminergic Neurodegeneration: Possible Implication in Parkinson's Disease Incidence PARKINSONS DISEASE
Artículo2011 Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus NEUROBIOLOGY OF AGING
Artículo2010 Comparative Study of the in Vitro Protective Effects of Several Antioxidants on Elongation Factor 2 under Oxidative Stress Conditions BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Artículo2010 Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: Role of monoamine oxidase enzyme NEUROTOXICOLOGY
Ponencia2010 Effect of aging and oxidative stress on elongation factor-2 in hypothalamus and hypophysis FEBS JOURNAL
Artículo2010 Expression of OCTN2 and OCTN3 in the Apical Membrane of Rat Renal Cortex and Medulla JOURNAL OF CELLULAR PHYSIOLOGY
Artículo2010 Ontogeny of d-Mannose Transport and Metabolism in Rat Small Intestine JOURNAL OF MEMBRANE BIOLOGY
Artículo2010 Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson's disease JOURNAL OF NEUROCHEMISTRY
Artículo2010 Use of haptoglobin and transthyretin as potential biomarkers for the preclinical diagnosis of Parkinson's disease NEUROCHEMISTRY INTERNATIONAL
Artículo2009 Adduct formation of 4-hydroxynonenal and malondialdehyde with elongation factor-2 in vitro and in vivo FREE RADICAL BIOLOGY AND MEDICINE
Artículo2009 Anti-aging medicine. What is that? APPROACHES TO AGING CONTROL
Artículo2009 Effects of thermo-oxidised oils on lipid peroxidation in experimental animals NUTRICION HOSPITALARIA
Ponencia2009 Observations on the Brain Development of the Sturgeon Acipenser naccarii BIOLOGY, CONSERVATION AND SUSTAINABLE DEVELOPMENT OF STURGEONS
Artículo2009 The intranigral injection of tissue plasminogen activator induced blood-brain barrier disruption, inflammatory process and degeneration of the dopaminergic system of the rat NEUROTOXICOLOGY
Artículo2008 Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide JOURNAL OF NEUROCHEMISTRY
Artículo2007 'In vitro' protective effect of a hydrophilic vitamin e analogue on the decrease in levels of elongation factor 2 in conditions of oxidative stress GERONTOLOGY
Artículo2007 A preliminary analysis of within-subject variation in human serum oxidative stress parameters as a function of time REJUVENATION RESEARCH
Resumen congreso2007 Creatine transport in rat colon: developmental maturation JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
Revisión2007 Mitochondrial toxins and neurodegenerative diseases FRONTIERS IN BIOSCIENCE-LANDMARK
Artículo2007 Proteomic identification of biomarkers in the cerebrospinal fluid in a rat model of nigrostriatal dopaminergic degeneration JOURNAL OF NEUROSCIENCE RESEARCH
Artículo2006 "In vitro" effect of lipid peroxidation metabolites on elongation factor-2 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo2006 Correlation between circulating biomarkers of oxidative stress of maternal and umbilical cord blood at birth FREE RADICAL RESEARCH
Artículo2006 Oxidative stress is increased in critically ill patients according to antioxidant vitamins intake, independent of severity: a cohort study CRITICAL CARE
Artículo2006 Stress increases vulnerability to inflammation in the rat prefrontal cortex JOURNAL OF NEUROSCIENCE
Artículo2005 Effects of short-term supplementation with folic acid on different oxidative stress parameters in patients with hypertension BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo2004 D-mannose transport and metabolism in isolated enterocytes GLYCOBIOLOGY
Artículo2004 Do the serum oxidative stress biomarkers provide a reasonable index of the general oxidative stress status? BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo2003 "In vitro" effect of cumene hydroperoxide on hepatic elongation factor-2 and its protection by melatonin BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo2003 Comparison of methods for sample preparation of individual rat cerebrospinal fluid samples prior to two-dimensional polyacrylamide gel electrophoresis BIOTECHNOLOGY LETTERS
Artículo2003 Effect of prenatal exposure to ethanol on hepatic elongation factor-2 and proteome in 21 D old rats: Protective effect of folic acid FREE RADICAL BIOLOGY AND MEDICINE
Artículo2003 Semichronic inhibition of glutathione reductase promotes oxidative damage to proteins and induces both transcription and translation of tyrosine hydroxylase in the nigrostriatal system FREE RADICAL RESEARCH
Artículo2002 Decrease of 1-methyl-1,2,3,4-tetrahydroisoquinoline synthesizing enzyme activity in the brain areas of aged rat BRAIN RESEARCH
Artículo2002 Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging - Correlation with post-translational modification of MR and decreased ADP-ribosylatable level of elongation factor 2 in kidney cells JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2001 A Na+-dependent D-mannose transporter in the apical membrane of chicken small intestine epithelial cells PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Artículo2001 Creatine transport in brush-border membrane vesicles isolated from rat kidney cortex JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Artículo2001 Hormonal regulation of chicken intestinal NHE and SGLT-1 activities American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Artículo2001 Na+-dependent D-mannose transport at the apical membrane of rat small intestine and kidney cortex BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Artículo2001 Protective effect of folic acid against oxidative stress produced in 21-day postpartum rats by maternal-ethanol chronic consumption during pregnancy and lactation period FREE RADICAL RESEARCH
Artículo2000 CNS voltage-dependent Na+ channel expression and distribution in an undifferentiated and differentiated CNS cell line BRAIN RESEARCH
Artículo2000 Protective effect of melatonin against the 1-methyl-4-phenylpyridinium-induced inhibition of Complex I of the mitochondrial respiratory chain JOURNAL OF PINEAL RESEARCH
Artículo2000 The endogenous amine 1-methyl-1,2,3,4-tetrahydroisoquinoline prevents the inhibition of complex I of the respiratory chain produced by MPP+ JOURNAL OF NEUROCHEMISTRY
Ponencia2000 Valor pedagógico de prácticas que utilizan la tecnología multimedia en la asignatura de Fisiología Celular Materiales para la calidad: actas de las II Jornadas Andaluzas de Calidad en la Enseñanza Universitaria : desarrollo de planes de calidad para la universidad
Artículo1999 Effects of aging on the various steps of protein synthesis: Fragmentation of elongation factor 2 FREE RADICAL BIOLOGY AND MEDICINE
Artículo1999 Induced mono-(ADP)-ribosylation of rat liver cytosolic proteins by lipid peroxidant agents FREE RADICAL BIOLOGY AND MEDICINE
Artículo1998 K+ transport in colonocytes isolated from the chick: Effect of anisosmotic buffers EXPERIMENTAL PHYSIOLOGY
Artículo1998 Use of Rotofor preparative isoelectrofocusing cell in protein purification procedure Applied Biochemistry and Biotechnology
Artículo1997 Low selenium diet increases the dopamine turnover in prefrontal cortex of the rat NEUROCHEMISTRY INTERNATIONAL
Artículo1997 Preferential use of less toxic detoxification pathways by long-lived species ARCHIVES OF GERONTOLOGY AND GERIATRICS
Artículo1997 Use of electrophoretic titration curves in the purification of a beta-1-3 glucanase from Oerskovia xanthineolytica BIOTECHNOLOGY TECHNIQUES
Artículo1996 Acción protectora del deprenilo frente a los daños oxidativos cerebrales producidos durante el envejecimiento Revista Española de Geriatría y Gerontología
Artículo1996 Apical ouabain sensitive K+-activated-ATPase activity in colon and caecum of the chick PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Artículo1996 Changes in superoxide dismutase activity in liver and lung of old rats FREE RADICAL RESEARCH
Artículo1996 Comparison of 5-hydroxy-2-aminovaleric acid with carbonyl groups content as a marker of oxidized protein in human and mouse liver tissues. FREE RADICAL BIOLOGY AND MEDICINE
Artículo1996 Effect of oxidative stress, produced by cumene hydroperoxide, on the various steps of protein synthesis - Modifications of elongation factor-2 JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo1996 Optimización de la I+D en la industria farmaceútica Industria Farmacéutica
Artículo1996 Oxidative inactivation of tyrosine hydroxylase in substantia nigra of aged rat FREE RADICAL BIOLOGY AND MEDICINE
Artículo1996 The utilization of 5-Hydroxy-2-Amino valeric acid as a specific marker of oxidized arginine and proline residues in proteins. FREE RADICAL BIOLOGY AND MEDICINE
Artículo1995 A convenient procedure for quantitative-analysis of stained or immunostained blotting membranes by densitometry BIOTECHNOLOGY TECHNIQUES
Artículo1995 Changes in the histidine-residues of cu/zn superoxide-dismutase during aging FEBS LETTERS
Artículo1995 Increase in dopamine turnover and tyrosine-hydroxylase enzyme in hippocampus of rats fed on low selenium diet JOURNAL OF NEUROSCIENCE RESEARCH
Artículo1995 K+‐H+ Exchange Activity in Brush‐Border Membrane Vesicles Isolated from Chick Small Intestine European Journal of Biochemistry
Artículo1995 Na+-H+ exchange activity in brush-border membrane-vesicles isolated from chick small-intestine BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Artículo1995 One-step electroblotting of 2- to 100-kDa proteins onto a PVDF membrane Applied Biochemistry and Biotechnology
Artículo1995 Utilización de ticlopidina en atención primaria. ATENCION PRIMARIA
Artículo1994 Kinetics of the chloride-anion exchanger of brush-border membrane-vesicles isolated from chicken jejunum BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Nota1994 Reduction of 1-methyl 1,2,3,4-tetrahydroisoquinoline level in substantia-nigra of the aged rat BRAIN RESEARCH
Artículo1993 Chloride transport in brush-border membrane-vesicles from chick jejunum PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Artículo1993 Direct quantitative determination of peptides and proteins in PVDF transfer membrane using a computing densitometer. PEPTIDE RESEARCH
Artículo1993 Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum Neuroscience Letters
Artículo1991 Involvement of diminution of glutathione, produced by deficiency of methionine in the diet, in the elevation of malic enzyme level in rat-liver BIOCHIMICA ET BIOPHYSICA ACTA
Artículo1991 Relationship between enzymatic-activity loss and posttranslational protein modification in aging ARCHIVES OF GERONTOLOGY AND GERIATRICS
Artículo1991 The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue MOLECULAR AND CELLULAR BIOCHEMISTRY
Artículo1990 Possible involvement of NADPH requirement in regulation of Glucose-6-Phosphate and 6-Phosphogluconate dehydrogenase levels in rat liver MOLECULAR AND CELLULAR BIOCHEMISTRY
Artículo1989 Implication of lysine residues in the loss of enzimatic activity in rat liver 6-phosphogluyconate dehydrogenase found in aging JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo1988 Possible involvement of histidine residues in the loss of enzymatic activity of rat liver malic enzyme during aging JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo1987 Measurement ex-vivo of the inhibition of fatty acids biosynthesis by bezafibrate administration in different rat tissues. JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo1986 Malic enzyme levels are increased by the activation of nadph-consuming pathways - detoxification processes FEBS LETTERS

Proyectos de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/09/2023 31/08/2027 Mecanismos y uso del hidroxitirosol e inhibidores del factor de elongación-2 para mejorar sinergeticamente la respuesta inmune antitumoral en carcinomas de células escamosas (PID2022-141577OB-I00) Ministerio de Ciencia e Innovación (Nacional) 237.500,00 €
01/09/2022 31/08/2025 Terapias dirigidas a modular la respuesta de macrófagos y microglia asociados al tumor (PID2021-126090OA-I00) Ministerio de Ciencia e Innovación (Nacional) 193.600,00 €
15/03/2011 30/04/2016 Estudio de los Mecanismos Moleculares que Regulan la Inflamación Cerebral y la Longevidad. Diseño de Estrategias Farmacológicas Encaminadas a Minimizar el Daño Neuronal Asociado a la Inflamación Cerebral en Modelos Animales de Enfermedades Neurodegenerativas (P10-CTS-6494) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 294.652,00 €
03/03/2011 03/03/2015 Estudio de los Cambios que Experimentan con el Envejecimiento las Rutas que Promueven la Supervivencia Celular y la Inflamación Cerebral: Modulación de las Mismas para Conseguir un Envejecimiento Saludable y Minimizar la Neurodegeneración (P09-CTS-5244) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 65.000,00 €
01/01/2011 31/12/2013 Significado Biológico de la Integración de los distintos Mecanismos de Regulación del Factor de Elongación-2 en Condiciones de Estrés Celular y Envejecimiento (BFU2010-20882) Ministerio de Ciencia e Innovación (Nacional) 114.950,00 €
01/01/2010 31/12/2010 Implicación de las interacciones de las rutas que aumentan la vida media y la supervivencia celular con el factor de elongación 2 en el mantenimiento de la síntesis de proteínas durante el envejecimiento (BFU2009-12307) Ministerio de Ciencia e Innovación (Nacional) 24.200,00 €
01/10/2007 04/10/2011 Estudio del proceso de eliminación de sinapsis: implicación en enfermedades degenerativas, Parkinson y Alzheimer (SAF2007-62425) Ministerio de Educación y Ciencia (Nacional) 219.010,00 €
01/10/2006 30/09/2009 Función de la reelina en la homeostasis del epitelio intestinal y renal (BFU2006-00720) Ministerio de Educación y Ciencia (Nacional) 72.600,00 €
01/10/2006 30/09/2009 Influencia del mantenimiento de la síntesis de proteínas durante el envejecimiento en el aumento del plazo de vida causado por la restricción claorica: importancia del factor de elongación 2 (BFU2006-06517) Ministerio de Educación y Ciencia (Nacional) 141.207,00 €
01/03/2006 28/02/2009 La enfermedad de Parkinson: Diagnostico en estado subclinico (EXC/2005/CTS-1014) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico) 235.000,00 €
13/12/2004 13/12/2007 Estudio de la influencia de la dopamina y el estrés en los procesos inflamatorios y degenerativos inducidos por la inyección de lipopolisacárido en el SNC (SAF2004-06601) Ministerio de Ciencia y Tecnología (Nacional) 154.900,00 €
01/01/2004 31/03/2007 Estudio del mecanismo de inhibición de la síntesis de proteínas por el envejecimiento y el estrés oxidativo y prevención de esta inhibición mediante el uso de compuestos antioxidantes y protectores (PI031233) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional) 59.340,00 €
15/11/2003 15/11/2006 Transporte de creatina por los epitelios intestinal y renal (BFI2003-00222) Ministerio de Ciencia y Tecnología (Nacional) 138.000,00 €
28/12/2001 27/12/2004 Degeneración del sistema dopaminérgico negro-estriado: marcadores de la velocidad de degeneración (Posible diagnóstico del estadio subclínico de la enfermedad de Parkinson); estudio de los mecanismos de supervivencia producido por GDNF y deprenilo (BFI2001-3600) Ministerio de Ciencia y Tecnología (Nacional) 120.262,51 €
01/07/2000 01/07/2003 Caracterización funcional y regulación del transporte de dmanosa por los epitelios intestinal y renal. Clonación del transportador apical de d-manosa (PM99-0121) Ministerio de Educación y Ciencia (Nacional) 72.121,45 €

Patentes

Nº Solicitud Fecha Solicitud Fecha Concesión Nombre
P201500766 05/07/2016 24/10/2019 Kit y método de cuantificación de la toxicidad en neuronas de la corteza cerebral para la detección de enfermedades neurodegenerativas