NEURODEGENERACIÓN - Prisma - Unidad de Bibliometría

MECANISMOS DE MUERTE CELULAR EN ENFERMEDADES NEURODEGENERATIVAS - BIO-113 (NEURODEGENERACIÓN)

Tipo de colectivo: Grupo de investigación
Estado: Grupo definitivo
Ámbito: Andalucía
Instituciones: Universidad de Sevilla
Fecha de creación: 01/01/1995

Investiga en

Tipo Año Título Fuente
Artículo2024 A proteomic approach supports the clinical relevance of TAT-Cx43266-283 in glioblastoma TRANSLATIONAL RESEARCH
Artículo2024 Analysis of patient referrals from primary care to ophthalmology. The role of the optometrist Journal of Optometry
Artículo2024 Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response CELL DEATH & DISEASE
Editorial2024 Editorial: Microglia in neurodegenerative diseases FRONTIERS IN CELLULAR NEUROSCIENCE
Artículo2024 Galectin-3 depletion tames pro-tumoural microglia and restrains cancer cells growth. CANCER LETTERS
Artículo2024 Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity Alzheimer's & Dementia
Artículo2024 Hydroxytyrosol and Parkinson’s disease: protective actions against alpha-synuclein toxicity NEURAL REGENERATION RESEARCH
Artículo2024 In Vivo PET Detection of Lung Micrometastasis in Mice by Targeting Endothelial VCAM-1 Using a Dual-Contrast PET/MRI Probe INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2024 Inflammatory bowel disease induces pathological α-synuclein aggregation in the human gut and brain NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
Artículo2024 Minimally Invasive Intracerebral Hemorrhage Evacuation Improves Pericavity Cerebral Blood Volume Translational Stroke Research
Artículo2024 Nerve injury triggers time-dependent activation of the locus coeruleus, influencing spontaneous pain-like behavior in rats. ANESTHESIOLOGY
Revisión2024 Standardization through education of molecular pathology: a spotlight on the European Masters in Molecular Pathology VIRCHOWS ARCHIV
Artículo2024 Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound THERANOSTICS
Artículo2024 The Gap Junction Inhibitor Octanol Decreases Proliferation and Increases Glial Differentiation of Postnatal Neural Progenitor Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2023 “Farmaling”: Implementación y adaptación de una plataforma virtual de simulación para la docencia de Biología Molecular y Biotecnología RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2023 A metagenome-wide association study of HIV disease progression in HIV controllers iScience
Artículo2023 Actin Polymerization Defects Induce Mitochondrial Dysfunction in Cellular Models of Nemaline Myopathies ANTIOXIDANTS
Artículo2023 Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells FRONTIERS IN NEUROSCIENCE
Artículo2023 ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. NATURE NEUROSCIENCE
Artículo2023 Caecum OX40+CD4 T-cell subset associates with mucosal damage and key markers of disease in treated HIV-infection JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
Corrección2023 Correction to: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease. ACTA NEUROPATHOLOGICA
Artículo2023 Diseño y perspectiva longitudinal de un proyecto de biotecnología farmacéutica basado en la economía circular RESCIFAR Revista Española de Ciencias Farmacéuticas
Editorial2023 Editorial: Factors contributing to dopaminergic cell death. FRONTIERS IN MOLECULAR NEUROSCIENCE
Artículo2023 FarmaEscape El Retorno: el empleo de una Escape Room como herramienta de aprendizaje en los estudios de la Facultad de Farmacia de la Universidad de Sevilla RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2023 Galectin-3 shapes toxic alpha-synuclein strains in Parkinson's disease. ACTA NEUROPATHOLOGICA
Artículo2023 Isolation and purification of fungal β-glucan as an immunotherapy strategy for glioblastoma JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
Artículo2023 Microglial Caspase-3 is essential for modulating hippocampal neurogenesis. BRAIN BEHAVIOR AND IMMUNITY
Artículo2023 Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease Translational Neurodegeneration
Resumen congreso2023 The deletion of Galectin-3 Reduces the Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon in two models of peripheral inflammation. GLIA
Revisión2022 APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases Molecular Neurodegeneration
Artículo2022 Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors JOURNAL OF CLINICAL INVESTIGATION
Artículo2022 Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner JOURNAL OF NEUROINFLAMMATION
Editorial2022 Editorial: The Role of the Immune Response in Brain Metastasis FRONTIERS IN ONCOLOGY
Artículo2022 Gal3 Plays a Deleterious Role in a Mouse Model of Endotoxemia INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2022 Galectin-3 is elevated in CSF and is associated with A beta deposits and tau aggregates in brain tissue in Alzheimer's disease ACTA NEUROPATHOLOGICA
Artículo2022 Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration CELL DEATH & DISEASE
Revisión2022 Inflammatory animal models of Parkinson's disease JOURNAL OF PARKINSONS DISEASE
Letter2022 Partial restoration of gut-mucosal dysbiosis in late-treated HIV-infected subjects with CD4 T-cell recovery Clinical and translational medicine
Corrección2022 The absence of caspase-8 in the dopaminergic system leads to mild autism-like behavior (vol 10, 839715, 2022) FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Artículo2022 The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Artículo2022 The HERC proteins and the nervous system. Seminars in Cell and Developmental Biology
Artículo2021 A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Artículo2021 Amyloid structural changes studied by infrared microspectroscopy in bigenic cellular models of alzheimer’s disease INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2021 Antioxidant effect of hydroxytyrosol, hydroxytyrosol acetate and nitrohydroxytyrosol in a rat MPP+ model of Parkinson’s disease NEUROCHEMICAL RESEARCH
Editorial2021 Editorial: Neurodegeneration: From Genetics to Molecules (Part II) FRONTIERS IN CELLULAR NEUROSCIENCE
Corrección2021 Erratum to “Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43266-283” [EBioMedicine 62, December 2020] DOI: https://doi.org/10.1016/j.ebiom.2020.103134 (EBioMedicine (2020) 62, (S2352396420305107), (10.1016/j.ebiom.2020.103134)) EBIOMEDICINE
Corrección2021 Erratum: Connexin43 peptide, TAT-Cx43266-283, selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo (Neuro-Oncology DOI: 10.1093/neuonc/noz243) NEURO-ONCOLOGY
Revisión2021 Evidences of hydroxytyrosol as an anti-inflammatory agent in Parkinson's disease: insights into the mechanisms of action NEURAL REGENERATION RESEARCH
Resumen congreso2021 Galectin-3 deletion reduces acute colitis-induced pro-inflammatory microglial activation in the ventral mensecephalon GLIA
Artículo2021 Galectin-3 deletion reduces LPS and acute colitis-induced pro-inflammatory microglial activation in the ventral mesencephalon FRONTIERS IN PHARMACOLOGY
Artículo2021 Hydroxycinnamic acid derivatives isolated from hempseed and their effects on central nervous system enzymes INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
Artículo2021 Purinergic receptor blockade with suramin increases survival of postnatal neural progenitor cells in vitro INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2021 Selective deletion of Caspase-3 gene in the dopaminergic system exhibits autistic-like behaviour PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Artículo2021 Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma ONCOGENE
Artículo2021 The human bone marrow harbors a CD45− CD11B+ cell progenitor permitting rapid microglia-like cell derivative approaches STEM CELLS TRANSLATIONAL MEDICINE
Artículo2021 The MHC class II transactivator modulates seeded alpha-synuclein pathology and dopaminergic neurodegeneration in an in vivo rat model of Parkinson's disease BRAIN BEHAVIOR AND IMMUNITY
Artículo2021 The other side of SARS-CoV-2 infection: neurological sequelae in patients. FRONTIERS IN AGING NEUROSCIENCE
Artículo2020 Connexin43 peptide, TAT-Cx43(266-283), selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo NEURO-ONCOLOGY
Artículo2020 Connexin43 region 266–283, via src inhibition, reduces neural progenitor cell proliferation promoted by egf and fgf-2 and increases astrocytic differentiation INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2020 Diagnosis and long-term outcome in dogs with acute onset intracranial signs Journal of Small Animal Practice
Artículo2020 HERC1 ubiquitin ligase is required for hippocampal learning and memory FRONTIERS IN NEUROANATOMY
Artículo2020 Hydroxytyrosol decreases lps-and α-synuclein-induced microglial activation in vitro ANTIOXIDANTS
Artículo2020 Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider FRONTIERS IN IMMUNOLOGY
Capítulo2020 Microglia-mediated neuroinflammation and Mediterranean diet The Mediterranean Diet: An Evidence-Based Approach
Revisión2020 Microglia: Agents of the CNS Pro-Inflammatory Response Cells
Artículo2020 STAT3-Mediated Astrocyte Reactivity Associated with Brain Metastasis Contributes to Neurovascular Dysfunction CANCER RESEARCH
Artículo2020 Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43(266)(-283) EBIOMEDICINE
Artículo2020 TET2, an “ambiguous” player in inflammation NEURAL REGENERATION RESEARCH
Revisión2020 The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2020 VCAM-1 targeted alpha-particle therapy for early brain metastases NEURO-ONCOLOGY
Revisión2019 Brainiac Caspases: Beyond the Wall of Apoptosis FRONTIERS IN CELLULAR NEUROSCIENCE
Artículo2019 Development of therapeutic anti-JAGGED1 antibodies for cancer therapy MOLECULAR CANCER THERAPEUTICS
Ponencia2019 El uso de una escape room como recurso docente en la Facultad de Farmacia IN-RED 2019: V Congreso de Innovación Educativa y Docencia en Red
Artículo2019 FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes Scientific reports
Resumen congreso2019 Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Artículo2019 Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease ACTA NEUROPATHOLOGICA
Revisión2019 Hydroxytyrosol protects from aging process via AMPK and autophagy; a review of its effects on cancer, metabolic syndrome, osteoporosis, immune-mediated and neurodegenerative diseases PHARMACOLOGICAL RESEARCH
Ponencia2019 Implementacion de una escape room multidisciplinar como herramienta de aprendizaje en la Facultad de Farmacia: Farmaescape Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Editorial2019 Magnetofection as a new tool to study microglia biology NEURAL REGENERATION RESEARCH
Revisión2019 Microglial subtypes: diversity within the microglial community EMBO JOURNAL
Revisión2019 Reformulating Pro-Oxidant Microglia in Neurodegeneration JOURNAL OF CLINICAL MEDICINE
Artículo2019 TET2 Regulates the Neuroinflammatory Response in Microglia CELL REPORTS
Artículo2019 VCAM-1-targeted MRI Enables Detection of Brain Micrometastases from Different Primary Tumors CLINICAL CANCER RESEARCH
Ponencia2018 Anti-vcam-1 targeted mri allows earlier detection of brain metastases in a xenograft melanoma mouse model NEURO-ONCOLOGY
Revisión2018 Caspases orchestrate microglia instrumental functions PROGRESS IN NEUROBIOLOGY
Artículo2018 Divergent Effects of Metformin on an Inflammatory Model of Parkinson's Disease FRONTIERS IN CELLULAR NEUROSCIENCE
Artículo2018 Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy of early brain metastases THERANOSTICS
Artículo2018 Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation FRONTIERS IN CELLULAR NEUROSCIENCE
Artículo2018 HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System MOLECULAR NEUROBIOLOGY
Artículo2018 Inflammation leads to distinct populations of extracellular vesicles from microglia JOURNAL OF NEUROINFLAMMATION
Artículo2018 Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer's disease mouse model 5xFAD Scientific reports
Revisión2018 Interactions Between Neural Progenitor Cells and Microglia in the Subventricular Zone: Physiological Implications in the Neurogenic Niche and After Implantation in the Injured Brain FRONTIERS IN CELLULAR NEUROSCIENCE
Revisión2018 Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response FRONTIERS IN CELLULAR NEUROSCIENCE
Ponencia2018 Monte Carlo evaluation of radionuclides for early brain metastases targeting INTERNAL MEDICINE JOURNAL
Artículo2018 Mutation of the HERC 1 Ubiquitin Ligase Impairs Associative Learning in the Lateral Amygdala MOLECULAR NEUROBIOLOGY
Artículo2018 Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles INTERNATIONAL JOURNAL OF NANOMEDICINE
Artículo2018 Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson's Disease FRONTIERS IN CELLULAR NEUROSCIENCE
Revisión2018 Phenolic Compounds Characteristic of the Mediterranean Diet in Mitigating Microglia-Mediated Neuroinflammation FRONTIERS IN CELLULAR NEUROSCIENCE
Revisión2018 Potential Use of Nanomedicine for the Anti-inflammatory Treatment of Neurodegenerative Diseases CURRENT PHARMACEUTICAL DESIGN
Artículo2018 RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation CELL DEATH & DISEASE
Artículo2018 The Multifarious Role of Microglia in Brain Metastasis FRONTIERS IN CELLULAR NEUROSCIENCE
Ponencia2017 A brain metastasis therapy tweak, for the better? concomitant stereotactic radiotherapy & molecular-targeted therapy NEURO-ONCOLOGY
Artículo2017 A c-Src Inhibitor Peptide Based on Connexin43 Exerts Neuroprotective Effects through the Inhibition of Glial Hemichannel Activity FRONTIERS IN MOLECULAR NEUROSCIENCE
Artículo2017 Anti-inflammatory Microglia/Macrophages As a Potential Therapeutic Target in Brain Metastasis FRONTIERS IN ONCOLOGY
Artículo2017 Covalent assembly of nanoparticles as a peptidase-degradable platform for molecular MRI NATURE COMMUNICATIONS
Artículo2017 CSP alpha, a Molecular Co-chaperone Essential for Short and Long-Term Synaptic Maintenance FRONTIERS IN NEUROSCIENCE
Ponencia2017 Development of two xenograft mouse models of brain metastasis for evaluation of anti-VCAM-1 targeted magnetic resonance imaging for micrometastasis detection CLINICAL & EXPERIMENTAL METASTASIS
Artículo2017 Fumarate decreases edema volume and improves functional outcome after experimental stroke EXPERIMENTAL NEUROLOGY
Artículo2017 Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration Scientific reports
Artículo2017 Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q(10) Deficiency STEM CELLS
Ponencia2017 Immunomodulatory roles of galectin-3 under conditions of neurodegeneration GLIA
Artículo2017 Interleukin-6 is increased in plasma and cerebrospinal fluid of community-dwelling domestic dogs with acute ischaemic stroke NEUROREPORT
Resumen congreso2017 Involvement of caspase-8 in microglial activation mediated by B-amyloid GLIA
Ponencia2017 Pheripheral inflamation exacerbates neuronal death in the mptp model of Parkinson's disease through microglial activation GLIA
Capítulo2017 Propiedades Sensoriales Análisis sensorial de los alimentos
Revisión2017 Targeting Neuroinflammation to Treat Alzheimer's Disease CNS DRUGS
Ponencia2017 The ambiguity of brain metastasis response to radiotherapy driven by cellular adhesion molecules NEURO-ONCOLOGY
Ponencia2017 Ulcerative colitis induces the activation of microglia in the ventral mesencephalon along with dopaminergic neuronal death GLIA
Artículo2016 AMPK function in aging process CURRENT DRUG TARGETS
Ponencia2016 Astrocyte activation by brain metastases alters neurovascular coupling JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Artículo2016 Caspase-8 inhibition represses initial human monocyte activation in septic shock model ONCOTARGET
Artículo2016 Change in autoantibody and cytokine responses during the evolution of neuromyelitis optica in patients with systemic lupus erythematosus: A preliminary study MULTIPLE SCLEROSIS
Ponencia2016 Characterization of circulating monocyte infiltration in brain metastasis CANCER RESEARCH
Artículo2016 Chronic and progressive Parkinson's disease MPTP model in adult and aged mice JOURNAL OF NEUROCHEMISTRY
Artículo2016 Chronic stress alters the expression levels of longevity-related genes in the rat hippocampus NEUROCHEMISTRY INTERNATIONAL
Artículo2016 Creating a Rat Model of Chronic Variate Stress Bio-Protocol
Ponencia2016 Development of an early brain metastasis geometric model for Geant4-DNA simulation EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Artículo2016 Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth ONCOTARGET
Artículo2016 Forced treadmill exercise can induce stress and increase neuronal damage in a mouse model of global cerebral ischemia NEUROBIOLOGY OF STRESS
Artículo2016 Galectin-3 causes enteric neuronal loss in mice after left sided permanent middle cerebral artery occlusion, a model of stroke Scientific reports
Artículo2016 Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype NATURE IMMUNOLOGY
Artículo2016 HERC 1 ubiquitin ligase mutation affects neocortical, CA3 hippocampal and spinal cord projection neurons: An ultrastructural study FRONTIERS IN NEUROANATOMY
Ponencia2016 Mechanistic pathways underlying altered neurovascular coupling in brain metastasis JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Artículo2016 Metformin, besides exhibiting strong in vivo anti-inflammatory properties, increases mptp-induced damage to the nigrostriatal dopaminergic system TOXICOLOGY AND APPLIED PHARMACOLOGY
Artículo2016 Mouse Models of Brain Metastasis for Unravelling Tumour Progression Advances in experimental medicine and biology
Corrección2016 PGC-1 alpha controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity (vol 7, pg 629, 2015) AGING-US
Artículo2016 Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion JOURNAL OF PHYSIOLOGY-LONDON
Artículo2016 Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke ACTA NEUROPATHOLOGICA COMMUNICATIONS
Artículo2016 The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination ONCOTARGET
Artículo2015 Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models STEM CELL REPORTS
Artículo2015 Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion CURRENT BIOLOGY
Ponencia2015 Cellular adhesion molecules and brain metastasis; how friends become foes CLINICAL & EXPERIMENTAL METASTASIS
Revisión2015 Collateral Damage: Contribution of Peripheral Inflammation to Neurodegenerative Diseases CURRENT TOPICS IN MEDICINAL CHEMISTRY
Artículo2015 Deletion of caspase-8 in mouse myeloid cells blocks microglia proinflammatory activation and confers protection in MPTP neurodegeneration model AGING-US
Artículo2015 Effect of intracerebral hydroxytyrosol and its nitroderivatives on striatal dopamine metabolism: A study by in vivo microdialysis LIFE SCIENCES
Artículo2015 Evaluation of a method for murine monocyte isolation by bone marrow depletion ANALYTICAL BIOCHEMISTRY
Artículo2015 Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation CELL REPORTS
Artículo2015 Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells FRONTIERS IN CELLULAR NEUROSCIENCE
Artículo2015 Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism JOURNAL OF NEUROINFLAMMATION
Artículo2015 PGC-1 alpha controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity AGING-US
Corrección2015 PGC-1 alpha controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity (vol 7, pg 629, 2015) AGING-US
Revisión2015 Relevance of chronic stress and the two faces of microglia in Parkinson's disease FRONTIERS IN CELLULAR NEUROSCIENCE
Artículo2015 Synergistic Deleterious Effect of Chronic Stress and Sodium Azide in the Mouse Hippocampus CHEMICAL RESEARCH IN TOXICOLOGY
Artículo2015 The HERC1 E3 Ubiquitin Ligase is essential for normal development and for neurotransmission at the mouse neuromuscular junction CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2014 alpha-Synuclein A30P decreases neurodegeneration and increases synaptic vesicle release probability in CSP alpha-null mice NEUROPHARMACOLOGY
Artículo2014 ASPP2 controls epithelial plasticity and inhibits metastasis through beta-catenin-dependent regulation of ZEB1 NATURE CELL BIOLOGY
Artículo2014 Chronic stress as a risk factor for Alzheimer's disease REVIEWS IN THE NEUROSCIENCES
Artículo2014 Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation JOURNAL OF NEUROINFLAMMATION
Ponencia2014 Effect of nitroderivatives of hydroxytyrosol on oxidative status and catechol-O-methyl transferase activity in rat's tissue BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2014 Functional role of endothelial adhesion molecules in the early stages of brain metastasis NEURO-ONCOLOGY
Artículo2014 Glial Activation in the Early Stages of Brain Metastasis: TSPO as a Diagnostic Biomarker JOURNAL OF NUCLEAR MEDICINE
Resumen congreso2014 HERC1 E3 UBIQUITIN LIGASE IS ESSENTIAL FOR NEUROTRANSMITTER RELEASE IN MOUSE NEUROMUSCULAR JUNCTION ACTA PHYSIOLOGICA
Ponencia2014 Implantación del Plan de Orientación y Acción Tutorial en la Facultad de Farmacia de la Universidad de Sevilla ARS PHARMACEUTICA
Artículo2014 Implanted neural progenitor cells regulate glial reaction to brain injury and establish gap junctions with host glial cells GLIA
Artículo2014 In vivo Effect of Apomorphine and Haloperidol on MPP+ Neurotoxicity PHARMACOLOGY
Artículo2014 In vivo striatal measurement of hydroxytyrosol, and its metabolite (homovanillic alcohol), compared with its derivative nitrohydroxytyrosol Neuroscience Letters
Artículo2014 Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1 alpha NATURE COMMUNICATIONS
Artículo2014 Neural Progenitor Cell Implants in the Lesioned Medial Longitudinal Fascicle of Adult Cats Regulate Synaptic Composition and Firing Properties of Abducens Internuclear Neurons JOURNAL OF NEUROSCIENCE
Artículo2014 Neurotransmitter release in motor nerve terminals of a mouse model of mild spinal muscular atrophy JOURNAL OF ANATOMY
Artículo2014 Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia CELL DEATH & DISEASE
Artículo2014 Role of dopamine in the recruitment of immune cells to the nigro-striatal dopaminergic structures NEUROTOXICOLOGY
Artículo2014 Stress and inflammation: a detrimental combination in the development of neurodegenerative disease Inflammation and Cell Signaling
Artículo2014 Structural and functional effects of metastases in rat brain determined by multimodal MRI INTERNATIONAL JOURNAL OF CANCER
Resumen congreso2014 Structural and functional synaptic changes are related with cognitive processes ACTA PHYSIOLOGICA
Artículo2014 The effect of hydroxytyrosol and its nitroderivatives on catechol-O-methyl transferase activity in rat striatal tissue RSC ADVANCES
Artículo2014 The role of Galectin-3 in α-synuclein-induced microglial activation ACTA NEUROPATHOLOGICA COMMUNICATIONS
Revisión2013 A brief overview of multitalented microglia HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Revisión2013 Caspases playing in the field of neuroinflammation: Old and new players DEVELOPMENTAL NEUROSCIENCE
Artículo2013 Fast motor axon loss in SMARD1 does not correspond to morphological and functional alterations of the NMJ NEUROBIOLOGY OF DISEASE
Artículo2013 Immunohistochemical detection of microglia HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Artículo2013 Intracranial Injection of LPS in Rat as Animal Model of Neuroinflammation HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Artículo2013 Magnetic resonance imaging reveals therapeutic effects of interferon-beta on cytokine-induced reactivation of rat model of multiple sclerosis JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Artículo2013 Motor learning of mice lacking cerebellar Purkinje cells FRONTIERS IN NEUROANATOMY
Artículo2013 Neural Progenitor Cell Implants Modulate Vascular Endothelial Growth Factor and Brain-Derived Neurotrophic Factor Expression in Rat Axotomized Neurons PLOS ONE
Editorial2013 Preface HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Revisión2013 Structural and functional maturation of active zones in large synapses MOLECULAR NEUROBIOLOGY
Artículo2013 Use of Confocal Microscopy in the Study of Microglia in a Brain Metastasis Model HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Artículo2012 Alpha-Haemoglobin regulates sympathoadrenal cell metabolism to maintain a catecholaminergic phenotype BIOCHEMICAL JOURNAL
Artículo2012 Atrofia Muscular Espinal Fisiología
Artículo2012 Molecular MRI enables early and sensitive detection of brain metastases PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2012 Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system NEUROTOXICOLOGY
Artículo2012 Role of early cell-free DNA levels decrease as a predictive marker of fatal outcome after severe traumatic brain injury CLINICA CHIMICA ACTA
Artículo2012 Synaptic defects in spinal muscular atrophy animal models DEVELOPMENTAL NEUROBIOLOGY
Artículo2012 T-type Ca2+ channels in mouse embryonic stem cells: modulation during cell cycle and contribution to self-renewal AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Artículo2012 The functional landscape of a presynaptic nerve terminal CELL CALCIUM
Artículo2011 Active zones and the readily releasable pool of synaptic vesicles at the neuromuscular junction of the mouse JOURNAL OF NEUROSCIENCE
Artículo2011 Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus Evidence in Parkinson's disease patients NEUROBIOLOGY OF DISEASE
Artículo2011 Caspase signalling controls microglia activation and neurotoxicity NATURE
Artículo2011 Inflammatory animal models for parkinson's disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons ISRN Neurology
Revisión2011 Nanostructures for Drug Delivery to the Brain CURRENT MEDICINAL CHEMISTRY
Revisión2011 Peripheral Inflammation Increases the Damage in Animal Models of Nigrostriatal Dopaminergic Neurodegeneration: Possible Implication in Parkinson's Disease Incidence PARKINSONS DISEASE
Artículo2011 SMN requirement for synaptic vesicle, active zone and microtubule postnatal organization in motor nerve terminals PLOS ONE
Artículo2011 Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus NEUROBIOLOGY OF AGING
Ponencia2011 Synthesis of hydroxytyrosol nitroderivatives as COMT inhibitors BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Revisión2011 The executioners sing a new song: killer caspases activate microglia CELL DEATH AND DIFFERENTIATION
Artículo2010 Altered Intracellular Ca2+ Homeostasis in Nerve Terminals of Severe Spinal Muscular Atrophy Mice JOURNAL OF NEUROSCIENCE
Artículo2010 Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy HUMAN MOLECULAR GENETICS
Artículo2010 Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: Role of monoamine oxidase enzyme NEUROTOXICOLOGY
Artículo2010 Effect of in vivo striatal perfusion of lipopolysaccharide on dopamine metabolites Neuroscience Letters
Libro2010 El estrés crónico como elemento potenciador de la degeneración de las neuronas del hipocampo inducida por inflamación: posible implicación en enfermedades neurodegenerativas El estrés crónico como elemento potenciador de la degeneración de las neuronas del hipocampo inducida por inflamación: posible implicación en enfermedades neurodegenerativas
Revisión2010 Proaging effects of stress: a review APPROACHES TO AGING CONTROL
Artículo2010 Striatal ablation of GABAergic neurons prevents the in vivo neuroprotective effect of DCG-IV against the MPP+-induced neurotoxicity on dopaminergic nerve terminals NEUROCHEMISTRY INTERNATIONAL
Artículo2010 Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson's disease JOURNAL OF NEUROCHEMISTRY
Artículo2010 Use of haptoglobin and transthyretin as potential biomarkers for the preclinical diagnosis of Parkinson's disease NEUROCHEMISTRY INTERNATIONAL
Artículo2009 Respiratory response to systemic inhibition of the Na+/H+ exchanger type 3 in intact rats RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
Artículo2009 Systemic Inhibition of the Na+/H+ Exchanger Type 3 in Intact Rats Activates Brainstem Respiratory Regions Arterial chemoreceptors
Artículo2009 The intranigral injection of tissue plasminogen activator induced blood-brain barrier disruption, inflammatory process and degeneration of the dopaminergic system of the rat NEUROTOXICOLOGY
Artículo2009 Zocor Forte (R) (simvastatin) has a neuroprotective effect against LPS striatal dopaminergic terminals injury, whereas against MPP+ does not EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2008 Cysteine string protein- is essential for the high calcium sensitivity of exocytosis in a vertebrate synapse EUROPEAN JOURNAL OF NEUROSCIENCE
Artículo2008 Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production NEUROTOXICOLOGY
Artículo2008 Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC Mutation JOURNAL OF CLINICAL MICROBIOLOGY
Artículo2008 Intracerebral VEGF injection highly upregulates AQP4 mRNA and protein in the perivascular space and glia limitans extema NEUROCHEMISTRY INTERNATIONAL
Artículo2008 Regional-specific regulation of BDNF and trkB correlates with nigral dopaminergic cell sprouting following unilateral nigrostriatal axotomy JOURNAL OF NEUROSCIENCE RESEARCH
Artículo2008 Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide JOURNAL OF NEUROCHEMISTRY
Artículo2008 The intrastriatal injection of thrombin in rat induced a retrograde apoptotic degeneration of nigral dopaminergic neurons through synaptic elimination JOURNAL OF NEUROCHEMISTRY
Artículo2007 Blood–brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons JOURNAL OF NEUROCHEMISTRY
Ponencia2007 Dexamethasone increases the neurotoxic effect of thrombin injection in the substantia nigra of the rat JOURNAL OF NEUROCHEMISTRY
Revisión2007 Mitochondrial toxins and neurodegenerative diseases FRONTIERS IN BIOSCIENCE-LANDMARK
Artículo2007 Monitoring synaptic function at the neuromuscular junction of a mouse expressing synaptopHluorin JOURNAL OF NEUROSCIENCE
Artículo2007 Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease STEM CELLS
Artículo2007 Proteomic identification of biomarkers in the cerebrospinal fluid in a rat model of nigrostriatal dopaminergic degeneration JOURNAL OF NEUROSCIENCE RESEARCH
Ponencia2007 Simvastatin prevent the inflammatory process and dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide JOURNAL OF NEUROCHEMISTRY
Artículo2006 Acute perfusion of BMAA in the rat's striatum by in vivo microdialysis TOXICOLOGY LETTERS
Artículo2006 Stress increases vulnerability to inflammation in the rat prefrontal cortex JOURNAL OF NEUROSCIENCE
Artículo2005 Blood-brain barrier disruption highly induces aquaporin-4 mRNA and protein in perivascular and parenchymal astrocytes: Protective effect by estradiol treatment in ovariectomized animals JOURNAL OF NEUROSCIENCE RESEARCH
Artículo2005 Deprenyl enhances the striatal neuronal damage produced by quinolinic acid MOLECULAR BRAIN RESEARCH
Artículo2005 Divergent regulatory mechanisms governing BDNF mRNA expression in cerebral cortex and substantia nigra in response to striatal target ablation EXPERIMENTAL NEUROLOGY
Artículo2005 Inflammatory process as a determinant factor for the degeneration of substantia nigra dopaminergic neurons JOURNAL OF NEURAL TRANSMISSION
Artículo2005 Kainate-induced zinc translocation from presynaptic terminals causes neuronal and astroglial cell death and mRNA loss of BDNF receptors in the hippocampal formation and amygdala JOURNAL OF NEUROSCIENCE RESEARCH
Artículo2005 Preliminary molecular genetic analysis of the Receptor Interacting Protein 140 (RIP140) in women affected by endometriosis Journal of Experimental and Clinical Assisted Reproduction
Artículo2005 Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice HUMAN MOLECULAR GENETICS
Artículo2004 Association of NOS3 gene with metabolic syndrome in hypertensive patients THROMBOSIS AND HAEMOSTASIS
Artículo2004 Dopamine-dependent neurotoxicity of lipopolysaccharide in substantia nigra FASEB JOURNAL
Revisión2004 Importance of Aquaporins in the Physiopathology of Brain Edema CURRENT PHARMACEUTICAL DESIGN
Artículo2004 In vivo expression of aquaporin-4 by reactive microglia JOURNAL OF NEUROCHEMISTRY
Revisión2004 Inflammatory process as a determinant factor for the degeneration of substantia nigra dopaminergic neurons: possible relevance to the etiology of Parkinson's disease CURRENT MEDICINAL CHEMISTRY
Artículo2004 Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system NEUROBIOLOGY OF DISEASE
Resumen congreso2004 Neuromuscular functional study of a mouse model of spinal muscular atrophy. BIOPHYSICAL JOURNAL
Ponencia2004 PET imaging of DAT with [F-18]FECNT in naive and Parkinsonian rats following embryonic stem cell transplantation NEUROIMAGE
Artículo2003 Detection of Pvull polymorphism within intron 1 of ESR1 gene by real-time PCR CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Artículo2003 Evidence for dopamine-derived hydroxyl radical formation in the nigrostriatal system in response to axotomy FREE RADICAL BIOLOGY AND MEDICINE
Artículo2003 Expression of BDNF mRNA in substantia nigra is dependent on target integrity and independent of neuronal activation JOURNAL OF NEUROCHEMISTRY
Artículo2003 Role of follicle-stimulating hormone receptor Ser680Asn polymorphism in the efficacy of follicle-stimulating hormone FERTILITY AND STERILITY
Artículo2003 Scanning of Y-chromosome azoospermia factors loci using real-time polymerase chain reaction and melting curve analysis FERTILITY AND STERILITY
Artículo2003 Semichronic inhibition of glutathione reductase promotes oxidative damage to proteins and induces both transcription and translation of tyrosine hydroxylase in the nigrostriatal system FREE RADICAL RESEARCH
Artículo2003 Specific CAPN10 Gene Haplotypes Influence the Clinical Profile of Polycystic Ovary Patients JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Artículo2003 Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia JOURNAL OF NEUROCHEMISTRY
Artículo2002 DCG-IV but not other group-II metabotropic receptor agonists induces microglial BDNF mRNA expression in the rat striatum. Correlation with neuronal injury NEUROSCIENCE
Artículo2002 Differential regulation of glutamic acid decarboxylase mRNA and tyrosine hydroxylase mRNA expression in the aged manganese-treated rats MOLECULAR BRAIN RESEARCH
Artículo2002 Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease NATURE
Artículo2002 Melatonin induces tyrosine hydroxylase mRNA expression in the ventral mesencephalon but not in the hypothalamus JOURNAL OF PINEAL RESEARCH
Artículo2002 Sonic hedgehog signalling in the developing and adult brain JOURNAL OF PHYSIOLOGY-PARIS
Artículo2002 The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-alpha, IL-1 beta and IFN-gamma JOURNAL OF NEUROCHEMISTRY
Artículo2001 Aquaporins in the central nervous system PROGRESS IN NEUROBIOLOGY
Artículo2001 Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction JOURNAL OF NEUROCHEMISTRY
Artículo2001 Long-lasting induction of brain-derived neurotrophic factor is restricted to resistant cell populations in an animal model of status epilepticus NEUROSCIENCE
Artículo2001 Potential role of endogenous brain-derived neurotrophic factor in long-term neuronal reorganization of the superior colliculus after bilateral visual deprivation NEUROBIOLOGY OF DISEASE
Artículo2001 Validity of a quantitative technique to study striatal dopaminergic neurodegeneration by in vivo microdialysis JOURNAL OF NEUROSCIENCE METHODS
Artículo2000 Decreased messenger RNA expression of key markers of the nigrostriatal dopaminergic system following vitamin E deficiency in the rat NEUROSCIENCE
Artículo2000 Histamine infusion induces a selective dopaminergic neuronal death along with an inflammatory reaction in rat substantia nigra JOURNAL OF NEUROCHEMISTRY
Artículo2000 Low selenium diet induces tyrosine hydroxylase enzyme in nigrostriatal system of the rat MOLECULAR BRAIN RESEARCH
Artículo2000 Neurotoxic relationship between dopamine and iron in the striatal dopaminergic nerve terminals BRAIN RESEARCH
Artículo2000 The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system NEUROBIOLOGY OF DISEASE
Artículo2000 Upregulation of BDNF mRNA and trkB mRNA in the nigrostriatal system and in the lesion site following unilateral transection of the medial forebrain bundle EXPERIMENTAL NEUROLOGY
Artículo1999 ¿Referees o lingüistas? Quark: Ciencia, medicina, comunicación y cultura
Artículo1999 Delayed apoptotic pyramidal cell death in CA4 and CA1 hippocampal subfields after a single intraseptal injection of kainate NEUROSCIENCE
Artículo1999 Detailed localization of aquaporin-4 messenger RNA in the CNS: Preferential expression in periventricular organs NEUROSCIENCE
Artículo1999 Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: Potential role in brain edema NEUROBIOLOGY OF DISEASE
Letter1999 Language bias discredits the peer-review system NATURE
Artículo1999 Localization of Aquaporin-3 mRNA and protein along the gastrointestinal tract of Wistar rats PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Artículo1999 Serotonin hyperinnervation in the adult rat ventral mesencephalon following unilateral transection of the medial forebrain bundle. Correlation with reactive microglial and astroglial populations NEUROSCIENCE
Ponencia1998 Dopamine and iron synergistic neurotoxic effect in striatal dopaminergic nerve terminals. EUROPEAN JOURNAL OF NEUROSCIENCE
Artículo1998 Influence of serotoninergic drugs on in vivo dopamine extracellular output in rat striatum JOURNAL OF NEUROSCIENCE RESEARCH
Artículo1998 Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system JOURNAL OF NEUROCHEMISTRY
Ponencia1998 Localization of the mRNAs for several aquaporins along the gastrointestinal tract of rats JOURNAL OF PHYSIOLOGY-LONDON
Artículo1998 Regionally specific induction of BDNF and truncated trkB.T1 receptors in the hippocampal formation after intraseptal injection of kainic acid BRAIN RESEARCH
Ponencia1998 Serotonin hyperinnervation in adult rat substantia nigra following axotomy: Correlation with glial activation. EUROPEAN JOURNAL OF NEUROSCIENCE
Artículo1997 (-)-Deprenyl treatment restores serum insulin-like growth factor-I (IGF-I) levels in aged rats to young rat level EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo1997 Chronic inhibition of the high-affinity dopamine uptake system increases oxidative damage to proteins in the aged rat substantia nigra FREE RADICAL BIOLOGY AND MEDICINE
Artículo1997 Deprenyl induces GFAP immunoreactivity in the intact and injured dopaminergic nigrostriatal system but fails to counteract axotomy-induced degenerative changes GLIA
Artículo1997 Deprenyl induces the tyrosine hydroxylase enzyme in the rat dopaminergic nigrostriatal system MOLECULAR BRAIN RESEARCH
Artículo1997 Developmental expression of 5-HT7 receptor mRNA in rat brain visual structures after neonatal enucleation NEUROREPORT
Artículo1997 Expression of 5-HT7 receptor mRNA in rat brain during postnatal development Neuroscience Letters
Artículo1997 Increased activity and expression of tyrosine hydroxylase in the rat substantia nigra after chronic treatment with nomifensine MOLECULAR PHARMACOLOGY
Artículo1997 Involvement of iron in MPP+ toxicity in substantia nigra: Protection by desferrioxamine BRAIN RESEARCH
Artículo1997 Lack of involvement of glutamate-induced excitotoxicity in MPP+ toxicity in striatal dopaminergic terminals: Possible involvement of ascorbate BRITISH JOURNAL OF PHARMACOLOGY
Artículo1997 Less induced 1-methyl-4-phenylpyridinium ion neurotoxicity on striatal slices from guinea-pigs fed with a vitamin C-deficient diet NEUROSCIENCE
Artículo1997 Low selenium diet increases the dopamine turnover in prefrontal cortex of the rat NEUROCHEMISTRY INTERNATIONAL
Artículo1997 Neuroprotective effect of the iron chelator desferrioxamine against MPP+ toxicity on striatal dopaminergic terminals JOURNAL OF NEUROCHEMISTRY
Revisión1997 Protective effects of neurotrophin-4/5 and transforming growth factor-alpha. On striatal neuronal phenotypic degeneration after excitotoxic lesioning with quinolinic acid NEUROSCIENCE
Artículo1997 Time course changes in the dopaminergic nigrostriatal system following transection of the medial forebrain bundle: detection of oxidatively modified proteins in substantia nigra JOURNAL OF NEUROCHEMISTRY
Artículo1996 Acción protectora del deprenilo frente a los daños oxidativos cerebrales producidos durante el envejecimiento Revista Española de Geriatría y Gerontología
Ponencia1996 Changes of the dopaminergic nigrostriatal system produced by transection of the medium forebrain bundle JOURNAL OF NEUROCHEMISTRY
Ponencia1996 Less-induced MPP(+) neurotoxicity on striatal slices from guinea-pigs fed with a vitamin C lacking diet JOURNAL OF NEUROCHEMISTRY
Artículo1996 MK-801 partially protects against the acute MPP(+) depleting effect on dopamine levels in rat striatal slices NEUROCHEMISTRY INTERNATIONAL
Artículo1996 Nigral and striatal comparative study of the neurotoxic action of 1-methyl-4-phenylpyridinium ion: Involvement of dopamine uptake system JOURNAL OF NEUROCHEMISTRY
Artículo1996 NT-4/5 protects against adrenalectomy-induced apoptosis of rat hippocampal granule cells NEUROREPORT
Artículo1996 Oxidative inactivation of tyrosine hydroxylase in substantia nigra of aged rat FREE RADICAL BIOLOGY AND MEDICINE
Artículo1996 Protection of the aged substantia nigra of the rat against oxidative damage by (-)-deprenyl BRITISH JOURNAL OF PHARMACOLOGY
Ponencia1996 The iron chelator desferrioxamine protects against MPP+ neurotoxicity. JOURNAL OF NEUROCHEMISTRY
Artículo1996 Trophic effect of exogenous nerve growth factor on rat striatal cholinergic neurons: Comparison between intraparenchymal and intraventricular administration MOLECULAR PHARMACOLOGY
Artículo1995 5-ht3 receptor agonist-induced carrier-mediated release of dopamine in rat striatum in-vivo BRITISH JOURNAL OF PHARMACOLOGY
Artículo1995 Analysis of ceftriaxone and ceftazidime distribution in cerebrospinal-fluid of and cerebral extracellular-space in awake rats by in-vivo microdialysis ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo1995 Complex-i inhibitor effect on the nigral and striatal release of dopamine in the presence and absence of nomifensine EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo1995 Effect of intraventricular-injection of 1-methyl-4-phenylpyridinium - protection by acetyl-l-carnitine Human & Experimental Toxicology: An International Journal
Artículo1995 Increase in dopamine turnover and tyrosine-hydroxylase enzyme in hippocampus of rats fed on low selenium diet JOURNAL OF NEUROSCIENCE RESEARCH
Artículo1995 Intrastriatal quinolinic acid injections protect against 6-hydroxydopamine induced lesions of the dopaminergic nigrostriatal system BRAIN RESEARCH
Ponencia1995 Nerve growth factor therapy for Alzheimer's disease: comparison with brain-derived neurotrophic factor RESEARCH ADVANCES IN ALZHEIMER'S DISEASE AND RELATED DISORDERS
Artículo1995 Retrograde transport of nerve growth-factor from hippocampus and amygdala to trka messenger-rna expressing neurons in paraventricular and reuniens nuclei of the thalamus NEUROSCIENCE
Artículo1995 THE EFFECT OF AGE ON THE MONOAMINES OF THE HYPOTHALAMUS MECHANISMS OF AGEING AND DEVELOPMENT
Artículo1994 6-hydroxydopamine lesions reduce bdnf messenger-rna levels in adult-rat brain substantia-nigra NEUROREPORT
Artículo1994 Do nerve-terminals and cell-bodies of nigrostriatal dopaminergic-neurons of the rat contain similar receptors Neuroscience Letters
Artículo1994 Effect of L-arginine nitric-oxide pathway on mpp(+)-induced cell injury in the striatum of rats BRITISH JOURNAL OF PHARMACOLOGY
Artículo1994 Expression of neurotrophin and trk receptor genes in adult-rats with fimbria transections - Effect of intraventricular nerve growth-factor and brain-derived neurotrophic factor administration NEUROSCIENCE
Artículo1994 Intrastriatal infusion of nerve growth-factor after quinolinic acid prevents reduction of cellular expression of choline-acetyltransferase messenger-rna and trka messenger-rna, but not glutamate-decarboxylase messenger-rna NEUROSCIENCE
Ponencia1994 Study of the 5-HT(3) agonist-induced dopamine release MONITORING MOLECULES IN NEUROSCIENCE
Artículo1994 The effect of experimental-ischemia and excitatory amino-acid agonists on the gaba and serotonin immunoreactivities in the rabbit retina NEUROSCIENCE
Artículo1993 Age-related-changes on monoamine turnover in hippocampus of rats BRAIN RESEARCH
Artículo1993 Aging and monoamine turnover in the lateral geniculate-nucleus and visual-cortex of the rat NEUROCHEMISTRY INTERNATIONAL
Artículo1993 Are bilateral nigrostriatal dopaminergic pathways functionally linked in the rat-brain - a microdialysis study in conscious rats BRAIN RESEARCH
Artículo1993 Effect of aging on monoamine turnover in the prefrontal cortex of rats MECHANISMS OF AGEING AND DEVELOPMENT
Artículo1993 Effects of a short-period of vitamin e-deficient diet in the turnover of different neurotransmitters in substantia-nigra and striatum of the rat NEUROSCIENCE
Artículo1993 Effects of age and dopamine agonists and antagonists on striatal dopamine release in the rat - an invivo microdialysis study MECHANISMS OF AGEING AND DEVELOPMENT
Artículo1993 In-vivo release of dopamine from rat striatum, substantia-nigra and prefrontal cortex - differential modulation by baclofen BRITISH JOURNAL OF PHARMACOLOGY
Artículo1993 NADPH diaphorase localization and nitric-oxide synthetase-activity in the retina and anterior uvea of the rabbit eye BRAIN RESEARCH
Artículo1993 Regulation of prefrontal cortical dopamine release by dopamine-receptor agonists and antagonists EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo1993 Regulation of the prefrontal cortical dopamine release by GABA(A) and GABA(B) receptor agonists and antagonists BRAIN RESEARCH
Artículo1993 TRKA NGF receptor expression by noncholinergic thalamic neurons NEUROREPORT
Artículo1992 Changes in neurotransmitter levels associated with the deficiency of some essential amino-acids in the diet BRITISH JOURNAL OF NUTRITION
Artículo1992 Changes in the turnover of monoamines in prefrontal cortex of rats fed on vitamin-e-deficient diet JOURNAL OF NEUROCHEMISTRY
Libro1992 Estudio del metabolismo de las aminas biógenas durante el desarrollo y envejecimiento en diferentes estructuras del sistema nervioso central Estudio del metabolismo de las aminas biógenas durante el desarrollo y envejecimiento en diferentes estructuras del sistema nervioso central
Artículo1992 Fast sodium-channel dependency of the somatodendritic release of dopamine in the rats brain Neuroscience Letters
Libro1992 Influencia de la edad sobre el metabolismo de las monoaminas en las estructuras cerebrales de la vía visual de la rata Influencia de la edad sobre el metabolismo de las monoaminas en las estructuras cerebrales de la vía visual de la rata
Artículo1992 Invivo evidence for a concordant response of terminal and dendritic dopamine release during intranigral infusion of drugs NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Artículo1992 Invivo protection of striatum from mpp+ neurotoxicity by n-methyl-d-aspartate antagonists BRAIN RESEARCH
Artículo1992 Simultaneous recording of the release of nigral and striatal dopamine in the awake rat NEUROCHEMISTRY INTERNATIONAL
Artículo1992 The release of dopamine from nerve-terminals and dendrites of nigrostriatal neurons induced by excitatory amino-acids in the conscious rat NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Artículo1992 The role of GABA receptors in the control of nigrostriatal dopaminergic-neurons - dual-probe microdialysis study in awake rats EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo1991 Acute effects of intranigral application of mpp+ on nigral and bilateral striatal release of dopamine simultaneously recorded by microdialysis BRAIN RESEARCH
Artículo1991 Age effects on monoamine turnover of the rat substantia-nigra BRAIN RESEARCH
Artículo1991 Characterization and pharmacological responsiveness of dopamine release recorded by microdialysis in the substantia-nigra of conscious rats JOURNAL OF NEUROCHEMISTRY
Ponencia1991 Dopamine release in adult and aged rats: comparison by microdialysis MONITORING MOLECULES IN NEUROSCIENCE
Artículo1991 Effects of neonatal bilateral eye enucleation on postnatal-development of the monoamines in posterior thalamus of the rat JOURNAL OF NEURAL TRANSMISSION
Artículo1991 Responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia-nigra JOURNAL OF NEUROCHEMISTRY
Ponencia1991 The connections of nigrostriatal dopaminergic-neurons studied by dual-probe microdialysis MONITORING MOLECULES IN NEUROSCIENCE
Artículo1991 The influence of age on neurotransmitter turnover in the rats superior colliculus NEUROBIOLOGY OF AGING
Artículo1991 The regulation of dopamine release from nigrostriatal neurons in conscious rats - the role of somatodendritic autoreceptors EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo1991 Turnover of dopamine and serotonin and their metabolites in the striatum of aged rats JOURNAL OF NEUROCHEMISTRY
Artículo1990 Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Artículo1990 Determination of levels of biogenic-amines and their metabolites and both forms of monoamine-oxidase in prefrontal cortex of aged rats MECHANISMS OF AGEING AND DEVELOPMENT
Artículo1990 Effects of enucleation on postnatal-development of catecholamines and serotonin metabolism in the superior colliculus of the rat BRAIN RESEARCH
Artículo1990 Hepatic hydrothorax without ascites: a rare form of a common complication JOURNAL OF THE ROYAL SOCIETY OF MEDICINE
Artículo1990 Neonatal enucleation alters catecholamine and serotonin metabolism in the lateral geniculate and visual-cortex in developing rats NEUROCHEMISTRY INTERNATIONAL
Artículo1990 Role of adenylate-cyclase in the modulation of the release of dopamine - a microdialysis study in the striatum of the rat JOURNAL OF NEUROCHEMISTRY
Artículo1989 Age-related changes of catecholamines and their metabolites content in the visual system of the rat MECHANISMS OF AGEING AND DEVELOPMENT
Artículo1989 CHANGES IN MONOAMINES AND THEIR METABOLITE LEVELS IN SUBSTANTIA NIGRA OF AGED RATS MECHANISMS OF AGEING AND DEVELOPMENT
Artículo1989 Determination of monoamines and both forms of monoamine-oxidase in the rats substantia nigra during postnatal-development LIFE SCIENCES
Artículo1988 Changes in biogenic-amines in rat hippocampus during development and aging LIFE SCIENCES
Artículo1987 Age-related-changes of serotonin and its metabolites content in the visual-system of the rat MECHANISMS OF AGEING AND DEVELOPMENT
Artículo1986 The change with age in biogenic-amines and their metabolites in the striatum of the rat ARCHIVES OF GERONTOLOGY AND GERIATRICS

Proyectos de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/09/2024 31/08/2027 Explorando el papel de la activación de las células microgliales en la progresión de la patología de la demencia frontotemporal (PID2023-146447OA-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 175.000,00 €
01/12/2023 30/11/2025 Effect of galectin-3 and its role in experimental models of Parkinson’s disease and Alzheimer’s Disease (GALENTIC-3) Lund University (Autonómico) 62.000,00 €
01/09/2022 31/08/2025 Terapias dirigidas a modular la respuesta de macrófagos y microglia asociados al tumor (PID2021-126090OA-I00) Ministerio de Ciencia e Innovación (Nacional) 193.600,00 €
01/09/2022 31/08/2025 Descifrando los subtipos de microglia deletérea potencialmente relevantes en enfermedades neurodegenerativas (PID2021-124096OB-I00) Ministerio de Ciencia e Innovación (Nacional) 290.400,00 €
11/01/2022 10/01/2024 Gb-Ap2 a Novel Blood-to-Brain Innumotherapy for Breast Cancer Brain Metastases (METAPREMIO 21) Asociación Española del Cáncer de Mama Metastásico (Nacional) 30.000,00 €
01/06/2020 29/02/2024 Contribución de las Caspasas-3 & 7 en la Etiología de la Enfermedad de Alzheimer (PID2019-107948RA-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 142.780,00 €
01/02/2020 30/04/2022 Anti -Galectin-3 as a Novel Immunotherapy for Globastoma Multiforme (US-1264152) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 30.000,00 €
01/02/2020 30/04/2022 Papel de la Galectina -3 en el Envejecimiento Cerebral (US-1264806) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 70.000,00 €
01/02/2020 30/04/2022 Study of the caspase-3 dependent mechanisms governing microglial activation in Parkinson's disease (US-1265062) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 30.000,00 €
01/01/2020 31/12/2022 Modulación de la activación microglial asociada a neurodegeneración, relevancia en enfermedades neurodegenerativas (P18-RT-1372) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico) 140.352,00 €
01/02/2019 31/01/2021 A novel innunotherrapy against brain metastasis: Anti-Galectin-3 (Gal3-BrainMets) (H2020-795695) Comisión Europea (Europeo) 170.121,60 €
01/01/2019 31/12/2021 Papel de la Galectina-3 en la Respuesta Inmune Asociada a Enfermedades del Sistema Nervioso Central. Implicación en Enfermedades Neurodegenerativas y Glioblastoma Multiforme (RTI2018-098645-B-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 193.600,00 €
01/01/2016 31/12/2018 Funciones Apoptóticas y no Apoptóticas de las Caspasas Asesinas en el Sistema Nervioso Central en Condiciones Normales y Patológicas (SAF2015-64171-R) Ministerio de Economía y Competitividad (Nacional) 275.880,00 €
24/12/2015 23/12/2016 Role of Galectin 3 in Parkinson's Disease Pathogenesis (11902) The Michael J. Fox Foundation For Parkinsons Research (Internacional) 51.318,89 €
01/01/2013 31/12/2015 Mecanismos Involucrados en la Recuperación de las Propiedades Fisiológicas de Motoneuronas e Interneuronas Lesionadas Tras el Tratamiento con Factores Neurotróficos y el Impla (BFU2012-33975) Ministerio de Economía y Competitividad (Nacional) 128.700,00 €
01/01/2013 31/12/2015 Sensibilidad al Oxígeno y Neurodegeneración (SAF2012-39343) Ministerio de Economía y Competitividad (Nacional) 468.000,00 €
01/01/2013 31/12/2015 Papel de la Caspasa-8 en el Proceso de Inflamación Cerebral Asociado a la Neurodegeneración (SAF2012-39029) Ministerio de Economía y Competitividad (Nacional) 128.700,00 €
01/01/2012 30/06/2013 Caspace-8 Control of Microglia Activation and Neuroxicity in Parkinson's Disease (CASPASE) Comisión Europea (Europeo) 30.000,00 €
15/03/2011 30/04/2016 Estudio de los Mecanismos Moleculares que Regulan la Inflamación Cerebral y la Longevidad. Diseño de Estrategias Farmacológicas Encaminadas a Minimizar el Daño Neuronal Asociado a la Inflamación Cerebral en Modelos Animales de Enfermedades Neurodegenerativas (P10-CTS-6494) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 294.652,00 €
03/03/2011 03/03/2015 Estudio de los Cambios que Experimentan con el Envejecimiento las Rutas que Promueven la Supervivencia Celular y la Inflamación Cerebral: Modulación de las Mismas para Conseguir un Envejecimiento Saludable y Minimizar la Neurodegeneración (P09-CTS-5244) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 65.000,00 €
01/01/2011 30/11/2014 Papel del Citoesqueleto y de la Mitocondria en la Patogenia de la Atrofia Muscular Espinal (BFU2010-21648) Ministerio de Ciencia e Innovación (Nacional) 196.020,00 €
01/01/2011 31/12/2013 Significado Biológico de la Integración de los distintos Mecanismos de Regulación del Factor de Elongación-2 en Condiciones de Estrés Celular y Envejecimiento (BFU2010-20882) Ministerio de Ciencia e Innovación (Nacional) 114.950,00 €
03/02/2010 02/08/2014 Aprovechamiento de Subproductos de la Industria Olivarera. Síntesis y Evaluación de Nuevos Antioxidantes con Potencial Aplicación en el Tratamiento del Parkinson (P09-AGR-5098) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 261.167,68 €
01/01/2010 31/12/2013 Dependencias tróficas en el sistema oculomotor. Efectos de factores derivados de la diana en la regulación de propiedades funcionales neuronales en modelos de lesión central y periférica. (BFU2009-07121) Ministerio de Ciencia e Innovación (Nacional) 181.500,00 €
01/01/2010 31/12/2012 Implicación del estrés crónico y la actividad DEVDasa en el mecanismo de activación microglial. Relevancia en el proceso de inflamación cerebral (SAF2009-13778) Ministerio de Ciencia e Innovación (Nacional) 84.700,00 €
01/01/2010 31/12/2012 Sensibilidad al oxígeno y neurodegeneración (SAF2009-12409) Ministerio de Ciencia e Innovación (Nacional) 605.000,00 €
01/01/2009 31/12/2011 Estudio de la posible influencia de los procesos inflamatorios periféricos sobre la degeneración del sistema dopaminérgico negro- estriatal (SAF2008-04366) Ministerio de Ciencia e Innovación (Nacional) 96.800,00 €
01/12/2007 30/11/2010 Estudio de la fisiología sináptica en tiempo real: regulación funcional de las zonas activas y modos de endocitosis (BFU2007-61771) Ministerio de Educación y Ciencia (Nacional) 145.200,00 €
01/10/2007 04/10/2011 Estudio del proceso de eliminación de sinapsis: implicación en enfermedades degenerativas, Parkinson y Alzheimer (SAF2007-62425) Ministerio de Educación y Ciencia (Nacional) 219.010,00 €
13/04/2007 31/10/2010 Visualización en tiempo real de la transmisión sináptica (P06-CVI-02392) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico) 214.000,00 €
01/01/2007 31/12/2012 Sensibilidad al oxígeno y neurodegeneración (CONFMB-001/2006) Fundación Marcelino Botín (Nacional) 220.000,00 €
01/10/2006 30/09/2009 Sensibilidad al oxígeno y neurodegeneración (SAF2006-08311) Ministerio de Educación y Ciencia (Nacional) 393.250,00 €
01/10/2006 30/09/2009 Estudio del papel del proteosoma y la barrera hematoencefálica en modelos animales de la enfermedad de parkinson (SAF2006-04119) Ministerio de Educación y Ciencia (Nacional) 133.100,00 €
01/03/2006 28/02/2009 La enfermedad de Parkinson: Diagnostico en estado subclinico (EXC/2005/CTS-1014) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico) 235.000,00 €
13/12/2004 13/12/2007 Estudio de la influencia de la dopamina y el estrés en los procesos inflamatorios y degenerativos inducidos por la inyección de lipopolisacárido en el SNC (SAF2004-06601) Ministerio de Ciencia y Tecnología (Nacional) 154.900,00 €
13/12/2004 13/12/2007 Estudio funcional en un modelo murino de atrofia muscular espinal del papel fisiológico de la proteína de supervivencia neuronal (SNM) en la unión neuromuscular (BFU2004-00350) Ministerio de Ciencia y Tecnología (Nacional) 106.950,00 €
15/11/2003 15/11/2006 Estudio de posibles mecanismos celulares de muerte celular en la enfermedad de Parkinson, búsqueda de terapias neuroprotectoras del sistema dopaminérgico nigro-estriado (SAF2003-01996) Ministerio de Ciencia y Tecnología (Nacional) 104.950,00 €
28/12/2001 27/12/2004 Degeneración del sistema dopaminérgico negro-estriado: marcadores de la velocidad de degeneración (Posible diagnóstico del estadio subclínico de la enfermedad de Parkinson); estudio de los mecanismos de supervivencia producido por GDNF y deprenilo (BFI2001-3600) Ministerio de Ciencia y Tecnología (Nacional) 120.262,51 €

Contratos

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
05/04/2011 04/05/2012 Nuevos genes potencialmente implicados en la emfermedad de Parkinson (1225/0478) Neocodex S.L. (Desconocido)
01/06/2010 31/12/2010 Estudio del potencial efecto neuroprotector in vivo de un compuesto de Noscira. (0798/0321) NOSCIRA, S.A. (Desconocido)
01/01/2010 31/03/2010 Determinación de la eficacia de un compuesto de NOSCIRA tras administración crónica en un modelo murino de muerte neuronal inducida por MPTP (0639/0321) NOSCIRA, S.A. (Desconocido)
01/01/2003 01/01/2004 Trabajo de carácter científico (SI-002/03) Rinat Neuroscience Corporation (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/01/2020 31/12/2020 Ayudas para el uso de los Servicios Generales de Investigación (PPI529/2020) Universidad de Sevilla (Local) 1.372,00 €
03/07/2010 07/07/2010 7th Fens Forum of European Neuroscience (PP2010-06-008) Universidad de Sevilla (Local) 600,00 €

Infraestructura

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/01/2013 31/12/2015 Acceso a la tecnología mesoscale discovery como herramienta analítica en los campos de inflamación, toxicología, neurodegeneración y metabolismo de la Universidad de Sevilla (UNSE13-1E-1995) Ministerio de Economía y Competitividad (Europeo) 36.006,00 €
El colectivo no tiene ningún resultado de investigación asociado