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Javier Avila Roman

Posdoctoral PPIT-FEDER
javieravila@us.es
Área de conocimiento: Farmacología
Departamento: Farmacología
Grupo: GRUPO DE INVESTIGACIÓN EN FARMACOLOGÍA MOLECULAR Y APLICADA - CTS-658 (Universidad de Sevilla)

Investiga en

Tipo Año Título Fuente
Artículo2024 Exploring Metabolic and Gut Microbiome Responses to Paraquat Administration in Male Wistar Rats: Implications for Oxidative Stress. ANTIOXIDANTS
Artículo2024 Functional features of the exopolysaccharide extracts produced by Lactiplantibacillus strains isolated from table olives. FOOD & FUNCTION
Artículo2024 Photoprotective Effects of Two New Morin-Schiff Base Derivatives on UVB-Irradiated HaCaT Cells. ANTIOXIDANTS
Artículo2024 Synthesis and Bioevaluation of New Stable Derivatives of Chrysin-8-C-Glucoside That Modulate the Antioxidant Keap1/Nrf2/HO-1 Pathway in Human Macrophages PHARMACEUTICALS
Artículo2023 9-PAHPA long term intake in DIO and db/db mice ameliorates insulin sensitivity but has few effects on obesity and associated metabolic disorders JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2023 Abrupt Photoperiod Changes Differentially Modulate Hepatic Antioxidant Response in Healthy and Obese Rats: Effects of Grape Seed Proanthocyanidin Extract (GSPE) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2023 Innovación docente de la asignatura optativa “Fitoterapia” en el Grado en Farmacia RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2023 Photoperiod conditions modulate serum oxylipins levels in healthy and obese rats: impact of proanthocyanidins and gut microbiota NUTRIENTS
Artículo2023 Rhythm and ROS: Hepatic Chronotherapeutic Features of Grape Seed Proanthocyanidin Extract Treatment in Cafeteria Diet-Fed Rats. ANTIOXIDANTS
Resumen congreso2023 Transetosomas co-cargados de carotenoides y polifenoles como estrategia de fotoprotección XVI Congreso SEFIG ( 16. 2023. Madrid): Libro de comunicaciones
Artículo2023 Up-Regulation of the Nrf2/HO-1 Antioxidant Pathway in Macrophages by an Extract from a New Halophilic Archaea Isolated in Odiel Saltworks ANTIOXIDANTS
Revisión2022 Cardioprotective Properties of Phenolic Compounds: A Role for Biological Rhythms MOLECULAR NUTRITION & FOOD RESEARCH
Capítulo2022 Microalgal bioactive components as antiinflammatory and antioxidant agents for health promotion Current advances for development of functional foods modulating inflammation and oxidative stress
Artículo2022 Time-of-day circadian modulation of Grape-Seed Procyanidin Extract (GSPE) in hepatic mitochondrial dynamics in cafeteria-diet-induced obese rats NUTRIENTS
Revisión2021 Anti-inflammatory and anticancer effects of microalgal carotenoids MARINE DRUGS
Artículo2021 Anti-inflammatory effects of rosmarinic acid-loaded nanovesicles in acute colitis through modulation of NLRP3 inflammasome BIOMOLECULES
Artículo2021 Blood pressure-lowering effect of wine lees phenolic compounds is mediated by endothelial-derived factors: role of sirtuin 1 ANTIOXIDANTS
Artículo2021 Enzyme-assisted extraction to obtain phenolic-enriched wine lees with enhanced bioactivity in hypertensive rats ANTIOXIDANTS
Artículo2021 Impact of gut microbiota on plasma oxylipins profile under healthy and obesogenic conditions CLINICAL NUTRITION
Capítulo2021 Oils and Oilseeds in the Nutraceutical and Functional Food Industries Oil and Oilseed Processing: Opportunities and Challenges
Revisión2021 Phenolic compounds and biological rhythms: who takes the lead? TRENDS IN FOOD SCIENCE & TECHNOLOGY
Artículo2021 Preparation and in vivo evaluation of rosmarinic acid-loaded transethosomes after percutaneous application on a psoriasis animal model AAPS PHARMSCITECH
Artículo2020 Modulation of food intake by differential TAS2R stimulation in rat NUTRIENTS
Artículo2020 New Eunicellin-Type Diterpenes from the Panamanian Octocoral Briareum Asbestinum MARINE DRUGS
Revisión2019 Chrononutrition and Polyphenols: Roles and Diseases NUTRIENTS
Artículo2019 Fucoxanthin and Rosmarinic Acid Combination Has Anti-Inflammatory Effects through Regulation of NLRP3 Inflammasome in UVB-Exposed HaCaT Keratinocytes MARINE DRUGS
Artículo2018 Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice MARINE DRUGS
Artículo2018 Microalgae-derived oxylipins decrease inflammatory mediators by regulating the subcellular location of NF kappa B and PPAR-gamma PHARMACOLOGICAL RESEARCH
Artículo2018 Topical Application of Glycolipids from Isochrysis galbana Prevents Epidermal Hyperplasia in Mice MARINE DRUGS
Artículo2016 Anti-inflammatory effects of an oxylipin-containing lyophilised biomass from a microalga in a murine recurrent colitis model BRITISH JOURNAL OF NUTRITION
Resumen congreso2016 Biological activity studies on marine natural products as therapeutic strategies in in vitro models of inflammation and colon cancer Biosaia
Artículo2016 Cytotoxic activity of microalgal-derived oxylipins against human cancer cell lines and their impact on ATP levels NATURAL PRODUCT COMMUNICATIONS
Artículo2016 Expression patterns of sirtuin 1-AMPK-autophagy pathway in chronic colitis and inflammation-associated colon neoplasia in IL-10-deficient mice International Immunopharmacology
Artículo2016 Goniothalamin prevents the development of chemically induced and spontaneous colitis in rodents and induces apoptosis in the HT-29 human colon tumor cell line TOXICOLOGY AND APPLIED PHARMACOLOGY
Artículo2016 The Algal Meroterpene 11-Hydroxy-1 '-O-Methylamentadione Ameloriates Dextran Sulfate Sodium-Induced Colitis in Mice MARINE DRUGS
Revisión2015 Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer MARINE DRUGS
Artículo2015 Inhibition of Chronic Ulcerative Colitis-associated Adenocarcinoma Development in Mice by VSL#3 INFLAMMATORY BOWEL DISEASES
Artículo2014 Oxylipins from the microalgae Chlamydomonas debaryana and Nannochloropsis gaditana and their activity as TNF-alpha inhibitors PHYTOCHEMISTRY
Artículo2014 Pharmacological characterization of Solanum cernuum Vell.: 31-norcycloartanones with analgesic and anti-inflammatory properties INFLAMMOPHARMACOLOGY
Artículo2014 Preventive effect of the microalga Chlamydomonas debaryana on the acute phase of experimental colitis in rats BRITISH JOURNAL OF NUTRITION
Artículo2012 Ácidos grasos poliinsaturados de microalgas inhiben la producción de TNF-a en células THP-1 y reducen la inflamación intestinal en un estudio animal: XXXIII Congreso Nacional de la SEF: premio Comunicaciones Orales Actualidad en Farmacología y Terapéutica
Revisión2012 Chemoprevention with Phytonutrients and Microalgae Products in Chronic Inflammation and Colon Cancer CURRENT PHARMACEUTICAL DESIGN
Artículo2011 Absolute Configuration of 7,8-seco-7,8-Oxacassane Diterpenoids from Acacia schaffneri JOURNAL OF NATURAL PRODUCTS
Artículo2011 Absolute configuration of labdanes and ent-clerodanes from Chrormolaena pulchella by vibrational circular dichroism PHYTOCHEMISTRY
Artículo2011 Absolute configuration of podophyllotoxin related lignans from Bursera fagaroides using vibrational circular dichroism PHYTOCHEMISTRY

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2021 31/05/2023 Investigador/a Evaluación del efecto protector de carotenoides, polifenoles y combinaciones de estos, frente al daño inflamatorio cutáneo inducido por la fotopolución. Acrónimo: PICAROPOL (US-1380844) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
30/01/2014 31/07/2018 Investigador/a Interés de los Polifenoles en Inflamación Crónica y Cáncer: Papel en los Sistemas Celulares de Regulación Mitocondrial y del Inflamasoma. Polfanat-II (P12-AGR-430) Consejería de Economía, Innovación y Ciencia (Autonómico)

Ayudas

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
17/07/2012 20/07/2012 Responsable "6th European Congress of Pharmacology, EPHAR 2012". Granada (PP2012-06-025) Universidad de Sevilla (Local)

Patentes

Nº Solicitud Fecha Solicitud Fecha Concesión Nombre
P201200097 01/02/2012 31/03/2014 Uso de oxilipinas y sus derivados como agentes antiinflamatorios
P201100461 26/04/2011 18/06/2013 Uso de compuestos diterpenoides como agentes antiinflamatorios y antitumorales