FAREXCLIN - Prisma - Unidad de Bibliometría

FARMACOLOGÍA EXPERIMENTAL Y FARMACIA CLÍNICA - CTS-259 (FAREXCLIN)

Tipo de colectivo: Grupo de investigación
Estado: Grupo definitivo
Ámbito: Andalucía
Instituciones: Universidad de Sevilla
Fecha de creación: 01/01/1995

Investiga en

Tipo Año Título Fuente
Artículo2024 Daidzein and Equol: Ex Vivo and In Silico Approaches Targeting COX-2, iNOS, and the Canonical Inflammasome Signaling Pathway PHARMACEUTICALS
Artículo2024 Dietary oleacein, a secoiridoid from extra virgin olive oil, prevents collagen-induced arthritis in mice FOOD & FUNCTION
Artículo2024 Functional features of the exopolysaccharide extracts produced by Lactiplantibacillus strains isolated from table olives. FOOD & FUNCTION
Artículo2024 Health-Promoting Properties of Pectin-Polyphenol Complex Extracted from Olive Oil By-Product Alperujo: Antioxidant, Antiproliferative, and Anti-Inflammatory Activities ANTIOXIDANTS
Artículo2024 Immunomodulatory Effects and Regulatory Mechanisms of (R)-6-HITC, an Isothiocyanate from Wasabi (Eutrema japonicum), in an Ex Vivo Mouse Model of LPS-Induced Inflammation JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2024 Isolation and structural determination of cis- and trans-p-coumaroyl-secologanoside (comselogoside) from olive oil waste (alperujo). Photoisomerization with ultraviolet irradiation and antioxidant activities FOOD CHEMISTRY
Artículo2023 (R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved FOOD & FUNCTION
Artículo2023 An Acid-Free Alternative to Pectin Production from the Cell Walls of Olive Oil Waste and Different Fruits Using Choline Chloride FOODS
Artículo2023 Aplicación de actividades colaborativas en los seminarios de Farmacología y Farmacoterapia III y Farmacia Clínica RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2023 Daratumumab-based therapies in transplant-ineligible patients with untreated multiple myeloma and hepatic dysfunction: A systematic review of subgroup analyses Journal of Oncology Pharmacy Practice
Resumen congreso2023 ECOE en las Prácticas Tuteladas del Grado en Farmacia de la Universidad de Sevilla XVI Congreso SEFIG ( 16. 2023. Madrid): Libro de comunicaciones
Artículo2023 Effects of dietary oleacein treatment on endothelial dysfunction and lupus nephritis in Balb/C pristane-induced mice. ANTIOXIDANTS
Artículo2023 Efficacy and safety of different antimicrobial DURATions for the treatment of Infections associated with Osteosynthesis Material implanted after long bone fractures (DURATIOM): protocol for a randomized, pragmatic trial PLOS ONE
Revisión2023 Epigenetic linkage of systemic lupus erythematosus and nutrition NUTRITION RESEARCH REVIEWS
Artículo2023 Extraction of polyphenols associated with pectin from olive waste (alperujo) with choline chloride FOOD CHEMISTRY
Artículo2023 Factors associated with COVID-19 vaccine uptake in a US/Mexico border community: demographics, previous influenza vaccination, and trusted sources of health information Frontiers in Public Health
Artículo2023 FarmaEscape El Retorno: el empleo de una Escape Room como herramienta de aprendizaje en los estudios de la Facultad de Farmacia de la Universidad de Sevilla RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2023 Innovación docente de la asignatura optativa “Fitoterapia” en el Grado en Farmacia RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2023 Oleocanthal Supplemented Diet Improves Renal Damage And Endothelial Dysfunction In Pristane-Induced Systemic Lupus Erythematosus In Mice FOOD RESEARCH INTERNATIONAL
Artículo2022 (−)-methyl-oleocanthal, a new oleocanthal metabolite reduces LPS-induced inflammatory and oxidative response: Molecular signaling pathways and histones epigenetic modulation ANTIOXIDANTS
Artículo2022 Adaptación transcultural a la versión española del cuestionario “Structured HIstory of Medication Use” para la conciliación de la medicación al ingreso MEDICINA CLINICA
Artículo2022 CD4+ and CD8+ T-cell responses in bone marrow to fatty acids in high-fat diets JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Revisión2022 Clinical and pharmacoeconomic impact of subgroup analysis in onco-hematological patients Supportive Care in Cancer
Artículo2022 Effects of Oleacein, a New Epinutraceutical Bioproduct from Extra Virgin Olive Oil, in LPS-Activated Murine Immune Cells. PHARMACEUTICALS
Systematic Review2022 Efficacy of early use of remdesivir: a systematic review of subgroup analysis. Revista Española de Quimioterapia
Artículo2022 Immunomodulatory effects of (R)-sulforaphane on LPS-activated murine immune cells: molecular signaling pathways and epigenetic changes in histone markers PHARMACEUTICALS
Resumen congreso2022 Implementación del servicio de asistencia en nuevos medicamentos (ANM) en pacientes hipertensos en farmacia comunitaria RESCIFAR Revista Española de Ciencias Farmacéuticas
Artículo2022 Ligstroside aglycon, an extra virgin olive oil secoiridoid, prevents inflammation by regulation of MAPKs, JAK/STAT, NF-κB, Nrf2/HO-1, and NLRP3 inflammasome signaling pathways in LPS-stimulated murine peritoneal macrophages FOOD & FUNCTION
Letter2022 Nivolumab Plus Ipilimumab for Previously Treated Stage IV Squamous Cell Lung Cancer JAMA Oncology
Editorial2022 Olive oil antioxidants ANTIOXIDANTS
Artículo2021 A new peracetylated oleuropein derivative ameliorates joint inflammation and destruction in a murine collagen-induced arthritis model via activation of the nrf-2/ho-1 antioxidant pathway and suppression of mapks and nf-κb activation NUTRIENTS
Artículo2021 Amoxicillin and clarithromycin mucoadhesive delivery system for helicobacter pylori infection in a mouse model: characterization, pharmacokinetics, and efficacy PHARMACEUTICS
Letter2021 Clinical Decision-Making about Neoadjuvant Nivolumab plus Ipilimumab JAMA Oncology
Corrección2021 Correction to: d-Pinitol: a cyclitol with versatile biological and pharmacological activities (Phytochemistry Reviews, (2020), 10.1007/s11101-020-09677-6) Phytochemistry Reviews
Revisión2021 d-Pinitol: a cyclitol with versatile biological and pharmacological activities Phytochemistry Reviews
Artículo2021 Dietary oleocanthal supplementation prevents inflammation and oxidative stress in collagen-induced arthritis in mice. ANTIOXIDANTS
Artículo2021 Impact of a multidisciplinary medication reconciliation program on clinical outcomes: a pre-post intervention study in surgical patients Research in Social and Administrative Pharmacy
Artículo2021 MUFAs in high-fat diets protect against obesity-induced bias of hematopoietic cell lineages MOLECULAR NUTRITION & FOOD RESEARCH
Artículo2021 Remdesivir and mortality reduction in COVID-19 patients: a systematized subgroup analysis of clinical trials FARMACIA HOSPITALARIA
Revisión2021 Use of docetaxel in low- and high-burden metastatic hormone-sensitive prostate cancer: a systematic review and assessment of subgroup analyses Journal of Oncology Pharmacy Practice
Artículo2020 An opinion on the regulation of bone marrow adipose tissue by dietary fatty acids GRASAS Y ACEITES
Artículo2020 Checklist for clinical applicability of subgroup analysis JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Capítulo2020 Diarrea por metotrexato Casos prácticos de farmacoterapia para farmacéuticos
Artículo2020 Dietary oleuropein and its acyl derivative ameliorate inflammatory response in peritoneal macrophages from pristane-induced SLE mice via canonical and noncanonical NLRP3 inflammasomes pathway FOOD & FUNCTION
Capítulo2020 Enfermedad de Crohn.Riesgos infecciosos asociados al tratamiento inmunomodulador. Casos prácticos de farmacoterapia para farmacéuticos
Capítulo2020 Hemorragia digestiva alta con repercusión hemodinámica asociada a lesiones agudas de la mucosa gástrica inducidas por antiinflamatorios no esteroides Casos prácticos de farmacoterapia para farmacéuticos
Capítulo2020 Hiperuricemia y gota: Complicaciones del tratamiento Casos prácticos de farmacoterapia para farmacéuticos
Revisión2020 Impact of medication reconciliation on health outcomes: An overview of systematic reviews Research in Social and Administrative Pharmacy
Capítulo2020 Infección por virus de la hepatitis B y lupus eritematoso sistémico en paciente pediátrica Casos prácticos de farmacoterapia para farmacéuticos
Artículo2020 MicroRNAs as potential predictors of extreme response to tyrosine kinase inhibitors in renal cell cancer Urologic Oncology: Seminars and Original Investigations
Capítulo2020 Oleic acid-the main component of olive oil on postprandial metabolic processes Olives and olive oil in health and disease prevention (Second Edition)
Artículo2020 Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function FOOD & FUNCTION
Capítulo2020 Optimización farmacocinética-farmacodinámica de meropenem en un paciente con fibrosis quística ingresado en un hospitalde tgercer nivel Casos prácticos de farmacoterapia para farmacéuticos
Artículo2020 Osteoarthritis treatment with a novel nutraceutical acetylated ligstroside aglycone, a chemically modified extra-virgin olive oil polyphenol Journal of Tissue Engineering
Capítulo2020 Paciente pluripatológico con intervención quirúrgica programada Casos prácticos de farmacoterapia para farmacéuticos
Artículo2020 Polyphenolic extract (PE) from olive oil exerts a potent immunomodulatory effect and prevents graft-versus-host disease in a mouse model BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
Revisión2020 Potential protective role exerted by secoiridoids from olea europaea l. In cancer, cardiovascular, neurodegenerative, aging-related, and immunoinflammatory diseases ANTIOXIDANTS
Capítulo2020 Somnolencia probablemente ocasionada por interacción entre baclofeno y un antigripal en paciente con insuficiencia renal Casos prácticos de farmacoterapia para farmacéuticos
Artículo2019 Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Ponencia2019 El uso de una escape room como recurso docente en la Facultad de Farmacia IN-RED 2019: V Congreso de Innovación Educativa y Docencia en Red
Artículo2019 Evaluación económica y análisis de impacto presupuestario de mepolizumab en asma eosinofílica refractaria grave FARMACIA HOSPITALARIA
Resumen congreso2019 Implementación de supuestos prácticos y una rúbrica de evaluación para su resolución en las prácticas tuteladas del grado en farmacia Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Ponencia2019 Implementacion de una escape room multidisciplinar como herramienta de aprendizaje en la Facultad de Farmacia: Farmaescape Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Ponencia2019 Instagram como recurso educativo en el aprendizaje de la farmacología Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Resumen congreso2019 Oleocanthal modulates LPS-induced murine peritoneal macrophages activation via regulation of inflammasome and Nrf-2/HO-1 signaling pathways BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2019 Oleocanthal modulates LPS-induced murine peritoneal macrophages activation via regulation of inflammasome, Nrf-2/HO-1, and MAPKs signaling pathways JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2019 Olive secoiridoid oleuropein and its semisynthetic acetyl-derivatives reduce LPS-induced inflammatory response in murine peritoneal macrophages via JAK-STAT and MAPKs signaling pathways JOURNAL OF FUNCTIONAL FOODS
Artículo2019 Olive-Oil-Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF-κB Pathway MOLECULAR NUTRITION & FOOD RESEARCH
Artículo2019 Polyphenolic extract from extra virgin olive oil inhibits the inflammatory response in IL-1 beta-activated synovial fibroblasts BRITISH JOURNAL OF NUTRITION
Artículo2019 Preventive effect of bergenin against the development of TNBS-induced acute colitis in rats is associated with inflammatory mediators inhibition and NLRP3/ASC inflammasome signaling pathways CHEMICO-BIOLOGICAL INTERACTIONS
Artículo2019 Quercus ilex extract ameliorates acute TNBS-induced colitis in rats PLANTA MEDICA
Revisión2019 Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018 NUTRIENTS
Artículo2018 Advanced sporadic renal epithelioid angiomyolipoma: Case report of an extraordinary response to sirolimus linked to TSC2 mutation BMC CANCER
Artículo2018 An Efficient and Practical Method for the Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols ADVANCED SYNTHESIS & CATALYSIS
Capítulo2018 Anemia Aprendizaje y aplicación práctica del modelo CMO de Atención Farmacéutica para alumnos del grado en Farmacia
Capítulo2018 Dislipemias Aprendizaje y aplicación práctica del modelo CMO de Atención Farmacéutica para alumnos del grado en Farmacia
Resumen congreso2018 Inhibitory effects of oleuropein and its peracetylated derivative on human osteoclastogenesis BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Resumen congreso2018 Oleuropein and its new acylated derivatives reduce lps-induced inflammatory response in murine peritoneal macrophages BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2018 Peracetylated hydroxytyrosol, a new hydroxytyrosol derivate, attenuates LPS-induced inflammatory response in murine peritoneal macrophages via regulation of non-canonical inflammasome, Nrf2/HO1 and JAK/STAT signaling pathways JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2018 Virgin olive oil and its phenol fraction modulate monocyte/macrophage functionality: a potential therapeutic strategy in the treatment of systemic lupus erythematosus BRITISH JOURNAL OF NUTRITION
Revisión2017 An update on diet and nutritional factors in systemic lupus erythematosus management NUTRITION RESEARCH REVIEWS
Revisión2017 Biomarkers of response to PD-1/PD-L1 inhibition CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Artículo2017 Dietary hydroxytyrosol and hydroxytyrosyl acetate supplementation prevent pristane-induced systemic lupus erythematous in mice JOURNAL OF FUNCTIONAL FOODS
Artículo2017 Extra-virgin olive oil phenols hydroxytyrosol and hydroxytyrosol acetate, down-regulate the production of mediators involved in joint erosion in human synovial cells JOURNAL OF FUNCTIONAL FOODS
Artículo2017 La caracterización de pacientes como herramienta útil para ofertar servicios profesionales personalizados en farmacia comunitaria FARMACEUTICOS COMUNITARIOS
Artículo2017 Oleuropein down-regulated IL-1 beta-induced inflammation and oxidative stress in human synovial fibroblast cell line SW982 FOOD & FUNCTION
Corrección2017 Oleuropein down-regulated IL-1 beta-induced inflammation and oxidative stress in human synovial fibroblast cell line SW982 (vol 8, pg 1890, 2017) FOOD & FUNCTION
Resumen congreso2017 Oleuropein exhibited anti-inflammatory and anti-oxidant activities in il-1 beta-stimulated human synovial fibroblasts BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2017 Single nucleotide polymorphisms as prognostic and predictive biomarkers in renal cell carcinoma ONCOTARGET
Artículo2017 The flavonol-enriched Cistus albidus chloroform extract possesses in vivo anti-inflammatory and anti-nociceptive activity JOURNAL OF ETHNOPHARMACOLOGY
Artículo2017 The phenolic fraction of extra virgin olive oil modulates the activation and the inflammatory response of T cells from patients with systemic lupus erythematosus and healthy donors MOLECULAR NUTRITION & FOOD RESEARCH
Revisión2016 An update on dietary phenolic compounds in the prevention and management of rheumatoid arthritis FOOD & FUNCTION
Artículo2016 Apigenin supplementation protects the development of dextran sulfate sodium induced murine experimental colitis by inhibiting canonical and non-canonical inflammasome signaling pathways JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2016 Dietary extra virgin olive oil attenuates kidney injury in pristane-induced SLE model via activation of HO-1/Nrf-2 antioxidant pathway and suppression of JAK/STAT, NF-kappa B and MAPK activation JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2016 Dietary extra-virgin olive oil prevents inflammatory response and cartilage matrix degradation in murine collagen-induced arthritis EUROPEAN JOURNAL OF NUTRITION
Artículo2016 Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation BLOOD
Revisión2016 Extra virgin olive oil: a key functional food for prevention of immune-inflammatory diseases FOOD & FUNCTION
Artículo2016 Extra-virgin olive oil and its phenolic extract prevent inflammatory response and joint damage in murine experimental arthritis GRASAS Y ACEITES
Artículo2016 Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp. NATURAL PRODUCT COMMUNICATIONS
Artículo2016 PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2a phosphorylation in established cell lines and primary human leukemia cells ONCOTARGET
Ponencia2015 Dietary hydroxytyrosol acetate prevents inflammatory response and joint damage in murine experimental arthritis BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2015 Dietary squalene supplementation improves DSS-induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways MOLECULAR NUTRITION & FOOD RESEARCH
Artículo2015 Effects of dietary virgin olive oil polyphenols: hydroxytyrosyl acetate and 3, 4-dihydroxyphenylglycol on DSS-induced acute colitis in mice JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Ponencia2015 Gb12, an isolated molecule from pelthophurum dubium, downregulates lpsinduced inflammatory response through stat3 inhibition in cultured murine peritoneal macrophages BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2015 Naturally Occurring Hydroxytyrosol Derivatives: Hydroxytyrosyl Acetate and 3,4-Dihydroxyphenylglycol Modulate Inflammatory Response in Murine Peritoneal Macrophages. Potential Utility as New Dietary Supplements JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2015 Preventive effects of dietary hydroxytyrosol acetate, an extra virgin olive oil polyphenol in murine collagen-induced arthritis MOLECULAR NUTRITION & FOOD RESEARCH
Resumen congreso2015 Protective effect of a quercus ilex l. mature leaves extract in a murine model of crohn's disease BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2015 Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages JOURNAL OF FUNCTIONAL FOODS
Ponencia2015 The use of blogs as an innovative teaching method for pharmacology and pharmacotherapy iii and clinical pharmacy subject BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2014 Anti-inflammatory and joint protective effects of a polyphenolic extract from extra virgin olive oil in type ii collagen-induced arthritis BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2014 Anti-inflammatory and joint protective effects of extra-virgin olive-oil polyphenol extract in experimental arthritis JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2014 Anti-inflammatory effects of Retama monosperma in acute ulcerative colitis in rats JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
Ponencia2014 Daidzein suppresses macrophage lps-induced inflammatory response via depressing stat-3 and p-38 mapk transcriptional activity BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2014 Experimental study of the efficacy of daptomycin for the treatment of cephalosporin-resistant pneumococcal meningitis JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2014 Experimental study of the efficacy of linezolid alone and in combinations against experimental meningitis due to Staphylococcus aureus strains with decreased susceptibility to beta-lactams and glycopeptides JOURNAL OF INFECTION AND CHEMOTHERAPY
Ponencia2014 Extra virgen olive oil polyphenol derivatives downregulate lps-induced inflammatory response in murine peritoneal macrophages suppressing nf kappa b signalling pathway BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2014 Extra virgin olive oil polyphenolic extracts downregulate inflammatory responses in LPS-activated murine peritoneal macrophages suppressing NF kappa B and MAPK signalling pathways FOOD & FUNCTION
Artículo2014 Melatonin modulates microsomal PGE synthase 1 and NF-E2-related factor-2-regulated antioxidant enzyme expression in LPS-induced murine peritoneal macrophages BRITISH JOURNAL OF PHARMACOLOGY
Revisión2014 Polio eradication initiative in Afghanistan, 1997-2013 JOURNAL OF INFECTIOUS DISEASES
Ponencia2014 Squalene modulates myeloid cells activation through mapk, nrf2, ppar gamma and mmp signalling pathways squalene modulates myeloid cells activation through mapk, nrf2, pparg and mmp signalling pathways BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2014 Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK BLOOD
Artículo2014 The unsaponifiable fraction of extra virgin olive oil promotes apoptosis and attenuates activation and homing properties of T cells from patients with inflammatory bowel disease FOOD CHEMISTRY
Artículo2014 Unsaponifiable fraction from extra virgin olive oil inhibits the inflammatory response in LPS-activated murine macrophages FOOD CHEMISTRY
Artículo2013 Abarema cochliacarpos reduces LPS-induced inflammatory response in murine peritoneal macrophages regulating ROS-MAPK signal pathway JOURNAL OF ETHNOPHARMACOLOGY
Artículo2013 An Up-date of Olive Oil Phenols in Inflammation and Cancer: Molecular Mechanisms and Clinical Implications CURRENT MEDICINAL CHEMISTRY
Artículo2013 Anti-inflammatory intestinal activity of Arctium lappa L. (Asteraceae) in TNBS colitis model JOURNAL OF ETHNOPHARMACOLOGY
Artículo2013 Dietary extra virgin olive oil polyphenols supplementation modulates DSS-induced chronic colitis in mice JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2013 Dietary unsaponifiable fraction from extra virgin olive oil supplementation attenuates acute ulcerative colitis in mice EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Ponencia2013 Extra virgin olive oil polyphenols downregulate lps-inflammatory reponse in murine macrophages suppressing nf kappa b and mapks signaling pathways BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2013 Fitoterapia Jornadas de Fitoterapia (2013).
Artículo2013 Fosfomycin-Daptomycin and Other Fosfomycin Combinations as Alternative Therapies in Experimental Foreign-Body Infection by Methicillin-Resistant Staphylococcus aureus ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2013 Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function BLOOD
Artículo2013 La fracción polifenólica del aceite de oliva virgen extra regula la respuesta inflamatoria inducida por LPS en macrófagos peritoneales de ratón mediante las vías de señalización Actualidad en Farmacología y Terapéutica
Artículo2013 Mechanisms Involved in the Antiproliferative and Proapoptotic Effects of Unsaponifiable Fraction of Extra Virgin Olive Oil on HT-29 Cancer Cells NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
Artículo2013 Oleuropein, a Secoiridoid Derived from Olive Tree, Inhibits the Proliferation of Human Colorectal Cancer Cell Through Downregulation of HIF-1 NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
Ponencia2013 Unsaponifiable frantion of extra virgin olive oil modulates t cell effector functions in patients with inflammatory bowel disease BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2012 Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats PHARMACOLOGICAL RESEARCH
Artículo2012 Efficacy of Daptomycin-Cloxacillin Combination in Experimental Foreign-Body Infection Due to Methicillin-Resistant Staphylococcus aureus ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Capítulo2012 El uso de crucigramas como método de innovación docente en la asignatura de Farmacia Clínica Estrategias para la enseñanza de la farmacología: experiencias docentes implementadas en España e Iberoamérica
Artículo2012 El uso de crucigramas como método de innovación docente en la asignatura de Farmacia Clínica: XXXIII Congreso Nacional de la SEF: premio Comunicaciones Orales Actualidad en Farmacología y Terapéutica
Artículo2012 Influence of extra virgin olive oil diet enriched with hydroxytyrosol in a chronic DSS colitis model EUROPEAN JOURNAL OF NUTRITION
Capítulo2012 Melatonin in cell fate decisions: Mechanistic perspectives and therapeutical potential Natural Compounds as Inducers of Cell Death
Artículo2012 Melatonin inhibits cell proliferation and induces caspase activation and apoptosis in human malignant lymphoid cell lines JOURNAL OF PINEAL RESEARCH
Revisión2012 Melatonin, A Natural Programmed Cell Death Inducer in Cancer CURRENT MEDICINAL CHEMISTRY
Letter2012 RNAIII inhibiting peptide against foreign-body infection by methicillin-resistant Staphylococcus aureus JOURNAL OF INFECTION
Revisión2012 Sirtuin Modulators: Mechanisms and Potential Clinical Implications CURRENT MEDICINAL CHEMISTRY
Editorial2011 An Up-Date of Olive Oil and Bioactive Constituents in Health: Molecular Mechanisms and Clinical Implications CURRENT PHARMACEUTICAL DESIGN
Ponencia2011 Anti-oxidant and anti-inflammatory activities of unsaponifiable fraction of extra virgin olive oil in murine peritoneal macrophages BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2011 Chemopreventive effect of dietary curcumin on inflammation-induced colorectal carcinogenesis in mice MOLECULAR NUTRITION & FOOD RESEARCH
Artículo2011 Chronic administration of Abarema cochliacarpos attenuates colonic inflammation in rats REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
Ponencia2011 Dietary pomegranate extract ameliorates chronic colitis. involvement of mitogen activated protein kinase pathways BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2011 Efficacy of tigecycline alone and with rifampin in foreign-body infection by methicillin-resistant Staphylococcus aureus JOURNAL OF INFECTION
Ponencia2011 Ellagic acid, a natural dietary polyphenol, supresses cox-2 expression in human monocyte thp-1/macrophages through mapk signalling pathway BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Libro2011 Guía del Farmacéutico Tutor de Farmacia Hospitalaria Guía del Farmacéutico Tutor de Farmacia Hospitalaria
Revisión2011 Polyphenols and Human Health: A Prospectus CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
Ponencia2011 Protective effect of an ellagic acid enriched-pomegranate extract, a natural polyphenolicrich fruit, in a murine model of crohn's disease BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2011 Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease BIOCHEMICAL PHARMACOLOGY
Artículo2011 Role of Different Inflammatory and Tumor Biomarkers in the Development of Ulcerative Colitis-associated Carcinogenesis INFLAMMATORY BOWEL DISEASES
Ponencia2011 The use of crosswords puzzles as an innovative teaching method for clinical pharmacy BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2011 Unsaponifiable fraction of extra virgin olive oil inhibits cell growth in ht-29 human colon adenocarcinoma cells: mechanisms and signaling pathways BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2010 Anti-inflammatory intestinal activity of Abarema cochliacarpos (Gomes) Barneby & Grimes in TNBS colitis model JOURNAL OF ETHNOPHARMACOLOGY
Artículo2010 Blocking of melatonin synthesis and MT1 receptor impairs the activation of Jurkat T cells CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2010 Caracterización de biomarcadores asociados con la colitis inflamatoria crónica y su transformación a neoplasia colorectal. Papel de adrenomedulina: XXXI Congreso Nacional de la SEF: comunicación oral premiada Actualidad en Farmacología y Terapéutica
Editorial2010 Commentary on 'Resveratrol commonly displays hormesis: Occurrence and biomedical significance' by Calabrese et al. Human & Experimental Toxicology: An International Journal
Artículo2010 Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2010 Efficacy of Usual and High Doses of Daptomycin in Combination with Rifampin versus Alternative Therapies in Experimental Foreign-Body Infection by Methicillin-Resistant Staphylococcus aureus ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2010 Extra-virgin olive oil-enriched diet modulates DSS-colitis-associated colon carcinogenesis in mice CLINICAL NUTRITION
Revisión2010 Olive oil and health: Summary of the II international conference on olive oil and health consensus report, Jaen and Cordoba (Spain) 2008 NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
Artículo2009 Age-related changes in melatonin synthesis in rat extrapineal tissues EXPERIMENTAL GERONTOLOGY
Artículo2009 Decreased MT1 and MT2 melatonin receptor expression in extrapineal tissues of the rat during physiological aging JOURNAL OF PINEAL RESEARCH
Artículo2009 Efficacy of High Doses of Daptomycin versus Alternative Therapies against Experimental Foreign-Body Infection by Methicillin-Resistant Staphylococcus aureus ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2009 Evidence of immune system melatonin production by two pineal melatonin deficient mice, C57BL/6 and Swiss strains JOURNAL OF PINEAL RESEARCH
Ponencia2009 In Vivo Characterization of Biomarkers Associated with Experimental Chronic Inflammation and Colon Cancer. Participation of Adrenomedullin GASTROENTEROLOGY
Artículo2009 Protective Effect of Curcumin, a Curcuma longa Constituent, in Early Colonic Inflammation in Rats DRUG DEVELOPMENT RESEARCH
Artículo2008 Acute and chronic responses associated with adrenomedullin administration in experimental colitis PEPTIDES
Ponencia2008 Age-related changes in melatonin synthesis in rat extrapineal tissues METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Editorial2008 Curcumin: A promising spice for therapeutics MOLECULAR NUTRITION & FOOD RESEARCH
Corrección2008 Effect of replacing glutamic residues upon the biological activity and stability of the circular enterocin AS-48 (vol 61, pg 1256, 2008) JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Capítulo2008 El aprendizaje tutelado como método de enseñanza en Farmacología y Farmacoterapia Experiencia de innovación universitaria: curso 2005/2006
Artículo2008 Experiencia en la docencia virtual de la asignatura "Prácticas Tuteladas" en la Facultad de Farmacia Revista de Enseñanza Universitaria
Ponencia2008 Extra-virgin olive oil-enriched diets modulate dextran sulphate sodium-induced colitis-associated neoplasia METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Ponencia2008 Influence of extra-virgin olive oil and curcumin-enriched diets on the prevention of experimental colorectal cancer associated with ulcerative colitis METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Ponencia2008 Inhibition of proliferation and induction of apoptosis by melatonin in human leukemia and lymphoma cells METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Revisión2008 Intestinal immunomodulation. Role of regulative peptides and promising pharmacological activities CURRENT PHARMACEUTICAL DESIGN
Artículo2008 Mechanisms of increased gastric protection after nsaid-administration in rats consuming virgin olive oil diets E-Spen
Revisión2008 New mechanisms and therapeutic potential of curcumin for colorectal cancer MOLECULAR NUTRITION & FOOD RESEARCH
Capítulo2008 Variantes metodológicas y adaptación de la función evaluadora en la asignatura de Farmacía Clínica Experiencia de innovación universitaria: curso 2005/2006
Capítulo2008 Zmiany W Obreie Ukladu Immunologicznego Zachodzace Wraz Z Wiekiemeva Aspekty Medyczne Starzenia Się Człowieka
Artículo2007 Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and NOS expression in chronic experimental colitis International Immunopharmacology
Artículo2007 Efecto protector del péptido adrenomedulina en la colitis inflamatoria experimental Actualidad en Farmacología y Terapéutica
Capítulo2007 El aprendizaje basado en los problemas como estrategia docente en los estudios de farmacología de farmacia Experiencia de innovación universitaria: curso 2004-2005
Artículo2007 Melatonin inhibits fatty acid-induced triglyceride accumulation in ROS17/2.8 cells: implications for osteoblast differentiation and osteoporosis American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Artículo2007 PARP inhibition reduces acute colonic inflammation in rats EUROPEAN JOURNAL OF PHARMACOLOGY
Revisión2007 Poly(ADP-ribose) polymerase inhibitors: New pharmacological functions and potential clinical implications CURRENT PHARMACEUTICAL DESIGN
Artículo2007 Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications BIOCHEMICAL SOCIETY TRANSACTIONS
Artículo2007 Rosiglitazone, a PPAR gamma ligand, modulates signal transduction pathways during the development of acute TNBS-induced colitis in rats EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2006 Acutely administered melatonin is beneficial while chronic melatonin treatment aggravates the evolution of TNBS-induced colitis JOURNAL OF PINEAL RESEARCH
Artículo2006 Melatonin and lipid uptake by murine fibroblasts: Clinical implications NEUROENDOCRINOLOGY LETTERS
Revisión2006 Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence JOURNAL OF PHARMACY AND PHARMACOLOGY
Revisión2006 Protective effects of melatonin in experimental free radical-related ocular diseases JOURNAL OF PINEAL RESEARCH
Artículo2006 The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model BRITISH JOURNAL OF PHARMACOLOGY
Artículo2005 COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions International Immunopharmacology
Revisión2005 Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications MOLECULAR NUTRITION & FOOD RESEARCH
Capítulo2005 Resveratrol as an antioxidant Resveratrol in Health and Disease
Artículo2005 Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces chronic colonic inflammation in rats BIOCHEMICAL PHARMACOLOGY
Artículo2005 The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice INFLAMMATION RESEARCH
Artículo2004 Effects of celecoxib on acid-challenged gastric mucosa of rats: Comparison with metamizol and piroxicam DIGESTIVE DISEASES AND SCIENCES
Artículo2004 Mucosal damage induced by preferential COX-1 and COX-2 inhibitors: Role of prostaglandins and inflammatory response LIFE SCIENCES
Revisión2004 New pharmacological perspectives and therapeutic potential of PPAR-gamma agonists CURRENT PHARMACEUTICAL DESIGN
Artículo2004 Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats BIOCHEMICAL PHARMACOLOGY
Artículo2004 Role of L-arginine in ibuprofen-induced oxidative stress and neutrophil infiltration in gastric mucosa FREE RADICAL RESEARCH
Artículo2004 Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, protects against gastric ischemia-reperfusion damage in rats: role of oxygen free radicals generation EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2003 A new flavonoid derivative, dosmalfate, attenuates the development of dextran sulphate sodium-induced colitis in mice International Immunopharmacology
Ponencia2003 Anti-inflammatory PGD(2) production after NSAID administration in a chronic experimenntal model of gastric lesion GASTROENTEROLOGY
Artículo2003 Antiulcer and antidiarrhoeic effect of Baccharis teindalensis PHARMACEUTICAL BIOLOGY
Artículo2003 Effects of dosmalfate, a new cytoprotective agent, on acute and chronic trinitrobenzene sulphonic acid-induced colitis in rats EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2003 Melatonin modulates the effects of gastric injury in rats: Role of prostaglandins and nitric oxide NEUROSIGNALS
Artículo2003 Preventive effect of zaprinast and 3-isobutyl, 1-methylxanthine (phosphodiesterase inhibitors) on gastric injury induced by nonsteroidal antiinflammatory drugs in rats DIGESTIVE DISEASES AND SCIENCES
Artículo2003 The cyclo-oxygenase-2 inhibitor, rofecoxib, attenuates mucosal damage due to colitis induced by trinitrobenzene sulphonic acid in rats EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2002 Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2002 Diurnal variation in the protective effect of melatonin against gastric injury caused by ischemia-reperfusion BIOLOGICAL RHYTHM RESEARCH
Artículo2002 Effects of dipyrone on inflammatory infiltration and oxidative metabolism in gastric mucosa - Comparison with acetaminophen and diclofenac DIGESTIVE DISEASES AND SCIENCES
Artículo2002 Effects of oxicam inhibitors of cyclooxygenase on oxidative stress generation in rat gastric mucosa. A comparative study FREE RADICAL RESEARCH
Artículo2002 Extra-virgin olive oil-enriched diets reduce indomethacin-induced gastric oxidative damage in rats DIGESTIVE DISEASES AND SCIENCES
Artículo2002 Gastric damage induced by subchronic administration of preferential cyclooxygenase-1 and cyclooxygenase-2 inhibitors in rats PHARMACOLOGY
Artículo2002 Gastric toxicity of racemic ketoprofen and its enantiomers in rat: oxygen radical generation and COX-expression INFLAMMATION RESEARCH
Artículo2002 Gastrointestinal tolerability of metamizol, acetaminophen, and diclofenac in subchronic treatment in rats DIGESTIVE DISEASES AND SCIENCES
Artículo2002 Mechanisms involved in protection afforded by L-arginine in Ibuprofen-induced gastric damage - Role of nitric oxide and prostaglandins DIGESTIVE DISEASES AND SCIENCES
Artículo2002 Mechanisms involved in the attenuation of intestinal toxicity induced by (S)-(+)-ketoprofen in re-fed rats DIGESTIVE DISEASES AND SCIENCES
Artículo2002 Role of prostaglandins and nitric oxide in gastric damage induced by metamizol in rats INFLAMMATION RESEARCH
Ponencia2001 Effects of COX-1 and COX-2 inhibitors on chronic gastric ulcer healing FUNDAMENTAL & CLINICAL PHARMACOLOGY
Artículo2001 Effects of food intake and oxidative stress on intestinal lesions caused by meloxicam and piroxicam in rats EUROPEAN JOURNAL OF PHARMACOLOGY
Ponencia2001 Effects of selective and non-selective COX-1 and COX-2 inhibitors on chronic gastric ulcer healing GASTROENTEROLOGY
Artículo2001 Mechanisms involved in gastric protection of melatonin against oxidant stress by ischemia-reperfusion in rats LIFE SCIENCES
Revisión2001 Mediterranean diet and health: Biological importance of olive oil CURRENT PHARMACEUTICAL DESIGN
Revisión2001 New issues about melatonin and its effects on the digestive system CURRENT PHARMACEUTICAL DESIGN
Ponencia2001 Opposite response of melatonin in experimental acute and chronic colitis in rats GASTROENTEROLOGY
Capítulo2000 Antiulcer and gastroprotective activity of flavonic compounds: Mechanisms involved STUDIES IN NATURAL PRODUCTS CHEMISTRY, VOL 53
Artículo2000 Effects of meloxicam on oxygen radical generation in rat gastric mucosa INFLAMMATION RESEARCH
Artículo2000 Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions JOURNAL OF ETHNOPHARMACOLOGY
Artículo2000 Intestinal toxicity of ketoprofen-trometamol vs its enantiomers in rat. Role of oxidative stress INFLAMMATION RESEARCH
Ponencia2000 Mechanisms is involved fv the attenuation of intestinal toxicity induced by S(+)ketoprofen in refed rat GASTROENTEROLOGY
Ponencia2000 Nitric oxide mechanisms in protection afforded by L-arginine in ibuprofen induced gastric toxicity. GASTROENTEROLOGY
Artículo1999 Protective effect of melatonin on indomethacin-induced gastric injury in rats JOURNAL OF PINEAL RESEARCH
Artículo1998 Anti-oxidant mechanisms involved in gastroprotective effects of quercetin ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Artículo1998 Consumo de analgésicos no narcóticos: Niveles de automedicación Farmacia Profesional
Artículo1998 Effects of cinitapride on gastric ulceration and secretion in rats INFLAMMATION RESEARCH
Ponencia1998 Extra virgin olive oil-enriched diets protects the NSAID-induced gastric damage in rats: Role of leukocyte adherence. GASTROENTEROLOGY
Ponencia1998 Lack of biochemical correlation between the protective effect of prostaglandins and nitric oxide pathway on NSAID-induced gastric injury. GASTROENTEROLOGY
Artículo1998 Salicylate consumption in the province of Seville Farmacia Clinica
Artículo1998 Uso racional de antiinflamatorios no esteroides en atención primaria ATENCION PRIMARIA
Artículo1997 Cinitapride protects against ethanol-lnduced gastric mucosal injury in rats: Role of 5-hydroxytryptamine, prostaglandins and sulfhydryl compounds PHARMACOLOGY
Artículo1997 Melatonin protects against gastric ischemia-reperfusion injury in rats JOURNAL OF PINEAL RESEARCH
Ponencia1997 Melatonin protects against NSAID-induced gastric injury in rats GUT
Ponencia1997 Preventive effect of zaprinast on NSAID-induced gastric injury GUT
Artículo1997 Protective effect of L-arginine against ibuprofen-induced gastric injury in rats Pharmaceutical Science & Technology Today
Artículo1997 Role of vascular mechanisms involved in the acute gastric mucosal injury induced by droxicam and piroxicam in rats Pharmaceutical Science & Technology Today
Artículo1997 Ulcer-protecting effects of a flavonoid fraction from Bidens aurea. Role of endogenous prostaglandins and microvascular permeability. PHYTOMEDICINE
Artículo1996 5-HT2 blockade protects against gastric ischaemia-reperfusion injury in rats. Role of oxygen free radicals and lipid peroxidation Pharmaceutical Sciences
Artículo1996 Antiulcer activity in rats by flavonoids of Erica andevalensis Cabezudo-Rivera PHYTOTHERAPY RESEARCH
Artículo1996 Antiulcerogenicity of the flavonoid fraction from Erica andevalensis Cabezudo-Rivera ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Artículo1996 Cytoprotective activity of cisapride on experimental gastric mucosal lesions induced by ethanol. Role of endogenous prostaglandins PROSTAGLANDINS & OTHER LIPID MEDIATORS
Artículo1996 Effects of cisapride on ulcer formation and gastric secretion in rats: Comparison with ranitidine and omeprazol GENERAL PHARMACOLOGY
Ponencia1996 Experimental gastric mucosal injury induced by different NSAID COX(1)/COX(2) inhibitors and protective action of L-arginine. Involvement of nitric oxide and neutrophil activation? GASTROENTEROLOGY
Artículo1996 Healing process induced by a flavonic fraction of Bidens aurea on chronic gastric lesion in rat. Role of angiogenesis and neutrophil inhibition ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Artículo1996 Nuevas perspectivas en el mecanismo de acción de los AINE Jano: Medicina y Humanidades
Artículo1996 Role of endogenous sulphydryls and neutrophil infiltration in the pathogenesis of gastric mucosal injury induced by piroxicam in rats INFLAMMATION RESEARCH
Artículo1996 Role of polymorphonuclear leukocytes and oxygen-derived free radicals in chronic gastric lesion induced by acetic acid in rat GENERAL PHARMACOLOGY
Artículo1996 The role of gastric mucosal sulphydryls in the ulcer-protecting effects of cisapride JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo1995 Aggravating process induced by indomethacin on chronic gastric lesion in rat. Role of polymorphonuclear leucocytes JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo1995 Gastroprotection induced by silymarin, the hepatoprotective principle of Silybum marianum in ischemia-reperfusion mucosal injury: Role of neutrophils PLANTA MEDICA
Ponencia1995 Influence of blood microcirculation on the acute nsaid-induced gastric injury GASTROENTEROLOGY
Artículo1995 Role of Mucus Secretion and Sulfhydryl Groups in Gastroprotection Mediated by a Flaysonoid Fraction of Bidens aurea ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Artículo1994 Antisecretory and gastroprotective effects of aescine in rats GENERAL PHARMACOLOGY
Artículo1994 Antiulcer and gastroprotective effects of quercetin: A gross and histologic study PHARMACOLOGY
Artículo1994 Antiulcerogenicity of the flavonoid fraction from bidens aurea - Comparison with ranitidine and omeprazole JOURNAL OF ETHNOPHARMACOLOGY
Artículo1994 Ulcer-protecting effects of naringenin on gastric-lesions induced by ethanol in rat - Role of endogenous prostaglandins JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo1993 Antiulcerogenic activity of aescine in different experimental-models PHYTOTHERAPY RESEARCH
Libro1993 Bases fisiopatológicas y farmacológicas de la úlcera péptica Bases fisiopatológicas y farmacológicas de la úlcera péptica
Artículo1993 Gastroprotection and prostaglandin-e(2) generation in rats by flavonoids of dittrichia-viscosa PLANTA MEDICA
Artículo1993 Quercetin and naringenin - effects on ulcer formation and gastric-secretion in rats PHYTOTHERAPY RESEARCH
Ponencia1992 Efecto gastroprotector de quercetina. Rol de prostaglandinas endogenas ARS PHARMACEUTICA
Ponencia1992 Efectos de la fracción favónica de Bidens aurea (aiton) sherff sobre la síntesis de moco gástrico en la úlcera por estrés: estudio comparativo con ranitidina y omeprazol ARS PHARMACEUTICA
Nota1992 Effects of naringenin and quercetin on experimental chronic gastric-ulcer in rat - studies on the histological-findings PHYTOTHERAPY RESEARCH
Ponencia1992 Estudio histomorfométrico e histoquímico de las modificaciones inducidas por quercetina sobre mucosa gástrica de rata en un modelo de ulceración provocado por etanol absoluto ARS PHARMACEUTICA
Artículo1992 Gastric anti‐ulcer activity of silymarin, a lipoxygenase inhibitor, in rats JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo1991 Effects of naringenin and silymarin on urinary excretion of water and electrolytes in rats PHYTOTHERAPY RESEARCH
Artículo1991 Esculine, ranitidine and carbenoxolone - different modes of action on gastric-mucosa GENERAL PHARMACOLOGY
Artículo1990 Contribución a la fitoterapia gastro duodenal El Farmaceutico
Artículo1990 Effects of aescine and aesculine on urinary excretion of water and electrolytes in rat Annales Pharmaceutiques Françaises
Artículo1988 Anti-ulcerogenicity of the flavonoid fraction from dittrichia viscosa (l.) w. greuter in rats PHYTOTHERAPY RESEARCH
Artículo1988 Antiinflammatory activity of Dittrichia viscosa (L.) W. Greuter Annales Pharmaceutiques Françaises
Nota1988 Constituents of essential oil of Thymus-carnosus Boiss JOURNAL OF CHROMATOGRAPHY A
Artículo1988 Gastric antiulcerous activity of different extracts of Dittrichia viscosa (L.) W. Greuter Annales Pharmaceutiques Françaises
Artículo1988 Isolation of caffeic and chlorogenic phenolic acids and orcinol from Dittrichia viscosa and study of their antimicrobial activities Plantes Medicinales et Phytotherapie
Artículo1988 Spamolytic activity of the flavonic fraction from Thymus carnosus Boiss Anales de la Real Academia Nacional de Farmacia
Artículo1987 Diuretic activity of several preparations from Thymus carnosus Boiss. Annales Pharmaceutiques Françaises
Artículo1987 Flavones isolated from Thymus carnosus Boiss. Annales Pharmaceutiques Françaises
Artículo1987 Investigation of antibiotic properties of the phenolic acids of Thymus carnosus Boiss. Isolation of caffeic, vanillic, p-coumaric, p-hydroxybenzoic and syringic acids Plantes Medicinales et Phytotherapie
Artículo1987 Trace constituents in the essential oil of Thymus carnosus Boiss. Plantes Medicinales et Phytotherapie
Artículo1986 Spasmolytic activity of essence and saturated water of Thymus carnosus Boiss. Annales Pharmaceutiques Françaises

Proyectos de Investigación

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/09/2023 31/08/2026 Diseño síntesis y aplicaciones terapéuticas de nuevos isotiocianatos derivados de carbohidratos como fármacos multidiana:Un enfoque basado en la polifarmacología (PID2022-138863OB-I00) Ministerio de Ciencia e Innovación (Nacional) 143.750,00 €
02/12/2022 31/12/2025 Funcionalidad del aceite de oliva virgen extra en la prevención de la artritis psoriásica: implicaciones epigenéticas (PROYEXCEL_00547) Junta de Andalucía (Consejería de Transformación Económica, Industria, Conocimiento y Universidades) (Autonómico) 158.179,65 €
01/12/2022 30/06/2025 Compuestos fenólicos de la hoja del olivo como nueva herramienta terapéutica para la espondiloartritis axial (TED2021-130708B-I00) Ministerio de Ciencia e Innovación (Nacional) 161.000,00 €
01/10/2022 30/09/2025 Cultivo sostenible de bayas de Corema album (L.) D. Don en el entorno de Doñana y su impacto en la salud humana (COREBERRY) (PLEC2022-009299) Ministerio de Ciencia e Innovación (Nacional) 259.994,60 €
01/09/2022 31/08/2025 Secoiridoides del olivo en la terapia nutricional del lupus eritematoso sistémico: implicaciones epigenéticas (PID2021-125488OB-I00) Ministerio de Ciencia e Innovación (Nacional) 119.790,00 €
01/01/2022 31/05/2023 Secoiridoides del olivo en la terapia nutricional de la artritis reumatoide: implicaciones epigenéticas y metabolómicas (US-1380592) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 90.000,00 €
05/10/2021 30/06/2023 Fármacos multidiana estructuralmente relacionados con isotiocianatos naturales: diseño, síntesis y aplicaciones terapéuticas (P20_01171) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico) 70.000,00 €
01/06/2020 31/01/2024 Los Carbohidratos y el Azufre como Herramientas Básicas en el Diseño y Síntesis de Nuevos Sistemas Moleculares Privilegiados de Interés Terapéutico y/o Sintético (PID2019-104767RB-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional) 90.750,00 €
01/01/2018 31/12/2021 Uso de formulaciones poliméricas mucoadhesivas para la erradicación de helicobacter pylori (RTC-2017-6643-1) Ministerio de Ciencia, Innovación y Universidades (Nacional) 127.947,00 €
01/01/2018 30/06/2021 Secoiridoides del olivo como nuevos nutracéuticos moduladores epigenéticos de la respuesta inmunoinflamatoria (AGL2017-89342-P) Ministerio de Economía y Competitividad (Nacional) 145.926,00 €
01/01/2015 31/12/2018 Desarrollo de formulaciones innovadoras con nanopartículas mucoadhesivas para el tratamiento de úlceras mucosales (NANOMUC) (RTC-2015-4437-1) Ministerio de Economía y Competitividad (Nacional) 139.697,50 €
01/01/2012 30/09/2015 Estudio Químico Biodirigido y Caracterización Farmacológica del Aceite de Oliva Virgen Extra en el Lupus Eritematoso Sistémico Experimental. (AGL2011-26949) Ministerio de Ciencia e Innovación (Nacional) 108.900,00 €
06/07/2011 31/07/2016 Valoración del Aceite de Oliva Virgen Extra en la Artritis Reumatoide Experimental: Estudio Biodirigido, Caracterización Farmacológica y Desarrollo de Ingredientes Funcionales (P10-AGR-6609) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico) 185.077,00 €
03/02/2010 03/02/2013 Caracterización química y farmacológica de polifenoles vegetales y su acción sobre sirtuínas. Polfanat (P09-AGR-5185) Junta de Andalucía (Consejería de Innovación, Ciencia y Empresas) (Autonómico) 167.133,68 €
01/01/2009 31/12/2011 Funcionalidad de la fracción insaponificable del aceite de oliva virgen extra en la prevención del cáncer colorrectal (AGL2008-02475) Ministerio de Ciencia e Innovación (Nacional) 121.000,00 €
13/04/2007 12/04/2010 Estudios inmunobiológicos y de degeneración neuronal parkinsoniana tras la inactivación génica de la biosíntesis (P06-CTS-01604) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico) 177.999,92 €
31/12/2005 31/12/2008 Influencia de dietas enriquecidas con aceite de oliva virgen extra y curcumina en la prevención de cáncer colorrectal asociado a colits experimental (AGL2005-05132) Ministerio de Educación y Ciencia (Nacional) 83.300,00 €
01/12/2002 01/12/2005 Mecanismos involucrados en la regulación del sistema inmune por melatonina durante el envejecimiento (SAF2002-00939) Ministerio de Ciencia y Tecnología (Nacional) 70.800,00 €

Contratos

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
30/10/2020 30/11/2020 Ensayo de validación del proceso de AM3 mediante la inhibición de la producción de factor de necrosis tumoral (TNF) inducida por endotoxina bacteriana (LPS) en modelo de macrófagos peritoneales murinos (3952/0990) Industrial Farmacéutica Cantabria, S.A. (Desconocido)
01/10/2008 30/06/2009 Estudio de obtención y valorización de biomasa a partir de microalgas (0245/0151) Aurantia 2003, S.L. (Desconocido)
17/10/2000 17/10/2001 Dosmalfato y enfermedad inflamatoria intestinal (OG-120/00) Laboratorios Faes, S.A. (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Denominación Agencia financiadora Importe concedido
01/01/2020 31/12/2020 Ayudas para el uso de los Servicios Generales de Investigación (PPI541/2020) Universidad de Sevilla (Local) 1.130,00 €
01/02/2011 31/08/2011 Estancias de movilidad en el extranjero (JC2010-0005) Ministerio de Educación (Nacional) 5.800,00 €
28/06/2010 30/11/2010 Encuentro grupo de investigación CTS-259 y empresas del sector agroalimentario y biotecnológico para llevar a cabo proyectos coordinados (OTR2010-CT15) Universidad de Sevilla (Oficina de Transferencia de Resultados de Investigación) (Local) 3.000,00 €
17/04/2010 21/04/2010 American Association of Cancer Research 101st Annual Meeting (PP2010-06-015) Universidad de Sevilla (Local) 600,00 €
16/03/2009 16/06/2009 Caracterización química y farmacológica de polifenoles vegetales y su acción sobre sirtuinas (POLFANAT) (OTRI/08-FCIE40) Universidad de Sevilla (Oficina de Transferencia de Resultados de Investigación) (Local) 3.000,00 €

Patentes

Nº Solicitud Fecha Solicitud Fecha Concesión Nombre
P201300916 24/09/2013 29/01/2016 Nuevos antiiflamatorios basados en polifenoles del olivo